sparfloxacin has been researched along with carbostyril in 313 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 289 (92.33) | 18.2507 |
| 2000's | 21 (6.71) | 29.6817 |
| 2010's | 3 (0.96) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hibi, H; Horiba, M; Naide, Y; Shinoda, M; Suzuki, K | 1 |
| Cobbs, CG; Smith, KR | 1 |
| Barrett, MS; Erwin, ME; Jones, RN; Koontz, FP | 1 |
| Arakawa, S; Fujii, A; Kamidono, S; Maeda, H; Nakata, K; Umezu, K | 1 |
| Finegold, SM; Molitoris, E; Wexler, HM | 1 |
| Almodovar, E; Burns, JJ; Qadri, SM; Rabea, N; Ueno, Y | 1 |
| Akaniro, JC; Arguedas, AG; Stutman, HR; Vargas, OM | 1 |
| Feistauer, SM; Georgopoulos, A; Georgopoulos, M; Graninger, W; Pfleger, S | 1 |
| Bergogne-Bérézin, E; Joly-Guillou, ML | 1 |
| Cantón, E; Gobernado, M; Jimenez, MT; Pemán, J; Ramón, MS | 1 |
| Hammerschlag, MR; Hyman, CL; Roblin, PM | 1 |
| Morrissey, I; Smith, JT | 1 |
| Gidoh, M; Tsutsumi, S | 1 |
| Bollet, C; de Lamballerie, X; de Micco, P; Gevaudan, MJ; Mallet, MN; Sambuc, R | 1 |
| Bebear, C; Renaudin, H | 1 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK | 2 |
| García, I; Guzman, MC; Pascual, A; Perea, EJ | 1 |
| Citron, DM; Goldstein, EJ | 2 |
| Iwagaki, A; Kobayashi, S; Matsumoto, K; Nagatake, T; Oishi, K; Sonoda, F | 1 |
| Kumazawa, J; Matsumoto, T; Nagayama, A; Tanaka, M | 1 |
| Giamarellou, H; Voutsinas, D; Xirouchaki, E | 1 |
| Kamisaka, K; Kawahara, S; Kibata, M; Konishi, H; Matsuyama, T; Mishima, Y; Shiomi, K; Tada, A; Takeuchi, M; Yoshimoto, S | 1 |
| Cars, O; Löwdin, E; Odenholt-Tornqvist, I | 1 |
| Borner, E; Borner, K; Lode, H | 1 |
| Fukuda, M; Sasaki, K | 3 |
| Azoulay-Dupuis, E; Bauchet, J; Bedos, JP; Pocidalo, JJ; Vallee, E; Veber, B | 1 |
| Cohen, Y; Grosset, J; Perronne, C; Pocidalo, JJ; Truffot-Pernot, C; Vildé, JL | 1 |
| Andrews, JM; Cooper, MA; Johnson, JH; Wise, R | 1 |
| Gelber, RH; Iranmanesh, A; Murray, L; Siu, P; Tsang, M | 1 |
| Kumamoto, Y | 1 |
| Lewin, CS; Morrissey, I; Smith, JT | 1 |
| Iwamoto, K; Katagiri, Y; Naora, K; Sekine, Y; Tanaka, K; Yamaguchi, T | 1 |
| Bauriaud, R; Escaffre, MC; Gaubert, E; Lareng, MB; Lefèvre, JC | 1 |
| Gutmann, L; Richard, P | 1 |
| Grosset, JH | 1 |
| Hirose, T; Miyake, M; Miyamoto, S; Miyao, N; Sato, T; Takatsuka, K; Tanaka, N; Umehara, T; Yokoo, A; Yoshiaki, K | 1 |
| Bouzard, D; Di Cesare, P; Fung-Tomc, J; Hoffmann, P; Kessler, R | 1 |
| Grosset, JH; Ji, B; Perani, EG; Petinon, C | 1 |
| Forstall, GJ; Knapp, CC; Washington, JA | 1 |
| Baltch, AL; Louie, A; Ritz, WJ; Smith, RP | 2 |
| Andrews, JM; Cooper, MA; Wise, R | 1 |
| Saito, H; Sato, K; Tomioka, H | 2 |
| Furet, YX; Michéa-Hamzehpour, M; Pechère, JC | 1 |
| Nitta, Y; Sagara, H; Tsunoda, T | 1 |
| Grosset, J; Ji, B; Truffot-Pernot, C | 1 |
| Chiba, K; Kagemoto, A; Kataoka, M; Nakao, M; Negoro, T; Ochi, T; Sekine, Y | 1 |
| Furukawa, H; Hashimoto, M; Matsunaga, Y; Miyazaki, H; Nambu, K; Oh-e, Y; Yoshida, K | 1 |
| Hashimoto, M; Matsunaga, Y; Miyazaki, H; Nomura, N | 1 |
| Ishibashi, Y; Nogita, T | 1 |
| Hibi, H; Horiba, M; Nagakubo, I; Naide, Y; Okishio, N; Shinoda, M; Suzuki, K; Yanagioka, M | 1 |
| Azoulay-Dupuis, E; Bergogne-Bérézin, E; Pocidalo, JJ; Vallée, E | 1 |
| Nishino, T; Okamoto, S; Okuda, J; Takahata, M | 1 |
| Piddock, LJ; Zhu, M | 1 |
| De Sousa, JP; Goh, KS; Labrousse, V; Rastogi, N | 1 |
| Cartwright, FD; Kenny, GE | 4 |
| Kamisaka, K; Kawahara, S; Kibata, M; Matsuyama, T; Mishima, Y; Nagare, J; Nakada, H; Tada, A; Yoshimoto, S | 1 |
| Andrews, JM; Ashby, JP; Cooper, MA; Matthews, RS; Wise, R | 1 |
| Aoki, N; Kouda, Y; Usuda, Y; Yoshikawa, H | 1 |
| Cagni, A; Chuard, C; Lew, DP; Schrenzel, J; Vaudaux, PE | 1 |
| Khac, SB; Moreau, NJ | 1 |
| Blanchard, A; Clavel, F; Grau, O; Montagnier, L; Quillent, C | 1 |
| Aoki, N; Arakawa, M; Usuda, Y; Wada, K; Yoshikawa, H | 1 |
| Iwamoto, Y; Miyake, Y; Okuda, K; Suginaka, H; Tsuruda, K | 1 |
| Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C | 1 |
| Gensberg, K; Jin, YF; Piddock, LJ | 1 |
| Carbon, C; Cochereau, I; Marrakchi-Benjaafar, S; Pocidalo, JJ | 1 |
| Chehl, SK; Gelber, RH; Murray, LP; Richard, V; Siu, P; Tsang, M | 1 |
| Bauernfeind, A | 1 |
| Citron, DM; Goldstein, EJ; Nesbit, CA | 1 |
| Braveny, I; Milatovic, D; Voss, A; Wallrauch, C | 1 |
| Blatter, M; Entenza, JM; Glauser, MP; Moreillon, P | 1 |
| Baron, MH; Chenon, MT; Coupry, C; Lecomte, S; Moreau, NJ | 1 |
| Carbon, C; Dautrey, S; Farinoti, R; Ramon, J; Rubinstein, E; St Julien, L | 1 |
| Jones, RN; Sutton, LD | 1 |
| Cantón, E; Pastor, A; Pemán, J | 1 |
| Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H | 1 |
| Kaatz, GW; Larsson, AJ; Moody, JA; Rotschafer, JC; Walker, KJ; Zabinski, RA | 1 |
| Gidoh, M; Hidaka, T; Matsuki, G; Nakamura, S; Tsutsumi, S | 1 |
| Avril, JL; Donnio, PY; Gastine, C; Travert, MF | 1 |
| Cooper, B; Freeman, C; Mazens-Sullivan, M; Nightingale, C; Quintiliani, R; Robinson, A | 1 |
| Cormican, MG; Jones, RN; Marshall, SA | 1 |
| Appelbaum, PC; Jacobs, MR; Pankuch, GA | 1 |
| Fujioka, H; Nakamura, Y; Shirai, Y; Sogo, K | 1 |
| Aoki, M; Goldstein, E; Kunii, O; Ono, Y | 1 |
| Chan, CY; Cheng, AF; Cheung, SW; Lyon, DJ | 1 |
| Cid, D; de la Fuente, R; Garcia, S; Piriz, S; Ruiz-Santa-Quiteria, JA; Vadillo, S; Valle, J | 1 |
| el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF | 1 |
| Anderson, MR; Brighty, KE; Castaldi, MJ; Gootz, TD; Haskell, SL; McGuirk, PR; Schmieder, BJ; Sutcliffe, JA | 1 |
| Cherubin, CE; Stratton, CW | 1 |
| Chin, NX; Neu, HC | 1 |
| Jones, RN; Rhomberg, PR | 1 |
| Bruno, R; Chassard, D; Ebmeier, M; Frydman, A; Guimart, C; Le Roux, Y; Montay, G; Thebault, JJ; Vergniol, JC | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Fresnadillo, MJ; García García, MI; García Sánchez, E; García Sánchez, JE; García-Rodríguez, JA; Trujillano, I | 1 |
| Cynamon, MH; Klemens, SP; Rogge, MC; Sharpe, CA | 1 |
| Aldridge, KE | 1 |
| Hattori, H; Nakamura, S; Nakata, K; Okazaki, Y | 1 |
| Boyce, ST; Holder, IA | 1 |
| Kamisaka, K; Kawahara, S; Kibata, M; Mishima, Y; Nagare, H; Okada, C; Soda, R; Tada, A; Takahashi, K; Takeuchi, M | 1 |
| Bruno, R; Dhib, M; Etienne, I; Fillastre, JP; Gay, G; Guimart, C; Le Roux, Y; Montay, G; Schott, D; Vivier, N | 1 |
| Irifune, K; Ishida, K; Kaku, M; Mizukane, R; Suyama, N; Takemura, H; Tanaka, H; Tomono, K; Usui, T; Yoshida, R | 1 |
| Acar, J; Baquero, F; Bergan, T; Degener, J; Forsgren, A; Phillips, I; Schito, GC; Wiedemann, B | 1 |
| Desnottes, JF; Diallo, N | 1 |
| Blanco, MT; Gómez-García, AC; Hurtado, C; Morán, FJ; Pérez-Giraldo, C; Rodríguez-Benito, A | 1 |
| Bermudez, LE; Inderlied, CB; Young, LS | 1 |
| Charter, M; Davey, PG; Freeman, A; Jacobson, I; Kelly, S; Lambert, J; Precious, E; Varma, TR | 1 |
| Hammerschlag, MR; Montalban, G; Roblin, PM | 1 |
| Martínez-Martínez, L; Ortega, MC; Perea, EJ; Suárez, AI | 1 |
| Borobio, MV; Conejo, M; Perea, EJ; Ramirez, E; Suarez, AI | 1 |
| Donabedian, SA; Perri, MB; Thal, LA; Vazquez, J; Zervos, MJ | 1 |
| Bron, AM; Garcher, CP; Guyonnet, GA; Kazmierczak, AM; Lecoeur, H; Pechinot, AP; Schott, DA | 1 |
| Chan, GP; Chavez, VE; Franzblau, SG; Garcia-Ignacio, BY; Jimenez, CL; Livelo, JB; Parrilla, ML | 1 |
| Banerjee, DK; McDermott-Lancaster, RD | 1 |
| Borner, K; Fassbender, M; Koeppe, P; Lode, H; Nord, CE; Ritz, M | 1 |
| Phillips, I; Power, EG | 1 |
| Akieda, Y; Itokawa, K; Kawaguchi, H; Kawamura, H; Nakayama, I; Suzuki, T; Watanabe, T; Yamaji, E | 1 |
| Croizé, J; Le Noc, D; Le Noc, P | 1 |
| Courdil, M; Escaffre, MC; Lareng, MB; Lefèvre, JC | 1 |
| Gillespie, SH; Kennedy, N | 1 |
| Denis, A; Moreau, NJ | 1 |
| Ishibashi, Y; Nogita, T; Shimada, J | 1 |
| Ahlén, S; Malmborg, AS | 1 |
| Andrews, JM; Brenwald, N; Wise, R | 1 |
| Iwagaki, A; Matsumoto, K; Nagatake, T; Oishi, K; Pollack, M; Ponglertnapagorn, P; Siadak, A; Sonoda, F; Watanabe, K | 1 |
| Grosset, J; Ji, B; Lalande, V; Paccaly-Moulin, A; Truffot-Pernot, C | 1 |
| Bauchet, J; Cochereau-Massin, I; Faurisson, F; Marrakchi-Benjaafar, S; Pocidalo, JJ; Saleh-Mghir, A; Vallee, E; Vallois, JM | 1 |
| Mitsuhashi, S; Yoshida, T | 1 |
| Beumer, H; Hoepelman, AI; Rozenberg-Arska, M; Verhoef, J; Visser, MR | 1 |
| Brumfitt, W; Hamilton-Miller, JM | 1 |
| Chan, GP; Franzblau, SG; Parrilla, ML | 1 |
| Amsterdam, D; Beam, TR; Gorzynski, EA; Mandell, LA; Rotstein, C | 1 |
| Fujioka, H; Kojima, K; Makita, H; Nakamura, Y; Shirai, Y; Sogo, K; Yamamoto, K | 1 |
| Barry, AL; Fuchs, PC; Pfaller, MA | 1 |
| Allen, SD; Baker, CN; Barry, AL; Fuchs, PC; Hardy, DJ; Jorgensen, JH; Murray, PR; Tenover, FC | 1 |
| García, I; Pascual, A; Perea, EJ; Ramirez de Arellano, E | 1 |
| Cormican, MG; Jones, RN | 1 |
| Hayashi, S; Horii, A; Iwai, Y; Kawano, M; Kishimoto, T; Nishisaka, N; Tsujino, T; Yasumoto, R | 1 |
| Dalhoff, A | 1 |
| Berche, P; Gaillot, O | 1 |
| Delidou, K; Grigoriadou, A; Pangalis, A; Paradelis, AG; Salpigides, G | 1 |
| Gaja, M; Saito, A | 1 |
| Chongchitmate, A; Rojnpisarnvong, V; Siristonpun, Y; Srimuang, S; Tanphaichitra, D | 1 |
| Verbist, L; Verhaegen, J | 1 |
| Argyriou, A; Kouvelas, D; Pangalis, A; Paradelis, AG; Salpigides, G | 1 |
| Barlier, AM; Carbon, C; Cormet, E; Farinotti, R; Huneau, JF; Rubinstein, E; Tomé, D | 1 |
| Hori, S; Kanemitsu, K; Shimada, J; Yanagawa, A | 1 |
| Barlow, D; Gianotti, B; Jean, C; Moi, H; Morel, P; Phillips, I | 2 |
| Brumpt, I; Grassi, GG | 1 |
| Hara, K; Ishida, K; Kaku, M; Koga, H; Kohno, S; Usui, T | 1 |
| Nakabayashi, M; Niki, Y; Soejima, R; Tamada, S | 1 |
| Asaoka, T; Imamori, K; Maebashi, K; Matsuda, H; Matsumoto, M; Tahara, Y | 1 |
| Angrisani, M; Cazzola, M; Contaldi, C; Loffreda, A; Losasso, C; Rossi, F | 1 |
| Blázquez, R; Bouza, E; Cercenado, E; Cotarelo, M; Sánchez-Carrillo, C; Vicente, T | 1 |
| Appelbaum, PC; Jacobs, MR; Visalli, MA | 1 |
| Iakovlev, SV; Iakovlev, VP; Izotova, GN | 1 |
| Garau, J; Grassi, C; Hosie, J; Huchon, G; Legakis, N; Lode, H; Segev, S; Wijnands, G | 1 |
| Blandino, G; Caccamo, F; Nicolosi, VM; Siracusa, V; Speciale, A | 1 |
| Alvarez, MP; Azanza, JR; Gries, JM; Honorato, J; Sadaba, B; Singlas, E; Taburet, AM | 1 |
| Bobin, P; Grosset, J; Ji, B; Lienhardt, C; Traore, I | 1 |
| Ibuki, E; Masuda, N; Miyoshi, H; Nishino, T; Otsuki, M; Takahashi, Y | 1 |
| Anzalone, G; Ouadrhiri, Y; Scorneaux, B; Tulkens, PM | 1 |
| Braun, S; Juliet, C; Nina, A; Prado, V; Salamanca, L; Trucco, O | 1 |
| Baquero, F; Cantón, R | 1 |
| Aznar, J; Garcia-Iglesias, MC; Pascual, A; Perea, EJ | 1 |
| Montay, G | 1 |
| Fujiwara, I; Mizuki, Y; Yamaguchi, T | 1 |
| Honeybourne, D; Wise, R | 1 |
| Caillon, R; Genevois, E; Lelouer, V; Vercken, JB | 1 |
| Aubier, M; Gialdroni-Grassi, G; Hosie, J; Huchon, G; Legakis, N; Lode, H; Regamey, C; Segev, S; Tolstuchow, N; Vester, R; Wijnands, WJ | 1 |
| May, T; Portier, H; Proust, A | 1 |
| Allegra, L; Guyen, JN; Hosie, J; Konietzko, N; Leophonte, P; Pauwels, R; Petitpretz, P | 1 |
| Berche, P; Gehanno, P | 1 |
| Barlow, D; Dimian, C; Moi, H; Perea, E; Phillips, I; Stolz, E; Weidner, W | 1 |
| di Silverio, F; Geddes, A; Guibert, J; Naber, KG | 1 |
| Rubinstein, E | 1 |
| Brumpt, I; Jaillon, P; Morganroth, J; Talbot, G | 1 |
| Iwamoto, Y; Mizutani, K; Takigawa, M; Tokura, Y | 1 |
| Cluzel, M; Dabernat, H; Derlot, E; Exmelin, L; Kitzis, MD; Le Noc, P; Muller-Serieys, C; Reverdy, ME; Scheftel, JM; Soussy, CJ; Thabaut, A | 1 |
| Dupont, H; Gachot, B; Regnier, B; Souweine, B; Timsit, JF; Wolff, M | 1 |
| Charransol, A; Demolis, JL; Funck-Brentano, C; Jaillon, P | 1 |
| Appelbaum, PC; Jacobs, MR; Lichtenberger, C; Pankuch, GA | 1 |
| Chilima, BZ; Okazawa, Y; Tanno, K; Tosaka, M; Yamane, N | 1 |
| Hayakawa, I; Hohmura, M; Hoshino, K; Ishida, H; Kitamura, A; Nishino, T; Sato, K; Tanaka, M | 1 |
| Belton, CM; Cartwright, FD; Fatherazi, S; Izutsu, KT; Kenny, GE; Oda, D | 1 |
| Chambers, HF; Hackbarth, CJ; Kocagöz, T; Nikaido, H; Rosenberg, EY; Unsal, I | 1 |
| Herrera-Insúa, I; Jacques-Palaz, K; Murray, BE; Rakita, RM | 2 |
| Borner, K; Koeppe, P; Ruhnke, M; Trautmann, M; Wagner, J | 1 |
| Belmatoug, N; Bleton, R; Carbon, C; Crémieux, AC; Garry, L; Manteau, M; Massias, L; Mazière, B; Mghir, AS; Sales, N | 1 |
| Cohen, MA; Talbot, GH; Yoder, SL | 1 |
| Aoun, M; Crokaert, F; Duchateau, V; Grenier, P; Klastersky, J; Vandermies, A | 1 |
| Breilh, D; Celerier, C; Dorian, M; Grellet, J; Leng, B; Pellegrin, JL; Rispal, P; Saux, MC | 1 |
| Rojnapisarnvong, V; Siristonpun, Y; Srimuang, S; Tanphaichitra, D | 1 |
| Düzgüneş, N; Flasher, D; Gangadharam, PR; Luna-Herrera, J; Reddy, MV | 1 |
| Ishii, N; Nakajima, H; Suga, C; Sugita, Y | 1 |
| Hecht, DW; Wexler, HM | 1 |
| Goldstein, EJ | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ; Salvador, J | 1 |
| Arvieux, C; Avril, JL; Cartier, F; Jacquelinet, C; Michelet, C; Vu, N | 1 |
| Cars, O; Jean, C; Ortqvist, A; Saikku, P; Valtonen, M; Wahl, M | 1 |
| Kato, M; Nomura, M; Shimoda, K | 1 |
| Bouras, M; Carbon, C; Cormet, E; Huneau, JF; Rubinstein, E; Tomé, D | 1 |
| Fisher, LM; Pan, XS | 1 |
| Bergogne-Bérézin, E; Houot, S; Joly-Guillou, ML; Moreau, NJ | 1 |
| Bourgeois, P; Cambau, E; Desplaces, N; Dion, E; Dubourg, G; Koeger, AC; Robin, H; Roche, B; Rozenberg, S; Vergeron, H | 1 |
| Davies, BI; Dirks-Go, SI; Hoogkamp-Korstanje, JA; Kabel, P; Manson, WL; Stobberingh, EE; Vreede, RW | 1 |
| Bryson, HM; Goa, KL; Markham, A | 1 |
| Mandell, GL; Townsend, GC | 1 |
| Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K | 1 |
| Bernard, FX; Bisch, D; Blanche, F; Cameron, B; Crouzet, J; Ferrero, L; Goniot, A; Lecoq, C; Manse, B; Maton, L; Ratet, N | 1 |
| Gutmann, L; Janoir, C; Kitzis, MD; Moreau, NJ; Zeller, V | 1 |
| Andrews, JM; Boswell, F; Brenwald, NP; Wise, R | 1 |
| Choi, EC; Choi, KH; Hong, JS; Kim, SK; Lee, DK; Yoon, SJ | 1 |
| Barry, AL; Brown, SD; Fuchs, PC | 1 |
| Citron, DM; Goldstein, EJ; Hudspeth, M; Hunt Gerardo, S; Merriam, CV | 1 |
| Barrett, MS; Jones, RN | 1 |
| Kawano, M; Kishimoto, T; Kyo, M; Nishisaka, N; Senju, M; Yasumoto, R | 1 |
| Borner, K; Koeppe, P; Lode, H; Schaberg, T; Schüler, P; Zemper, K | 1 |
| Barbeau, P; Lapeyre, C; Leng, B; Maugein, J; Pellegrin, I; Pellegrin, JL | 1 |
| Ambrose, PG; Nightingale, CH; Owens, RC; Quintiliani, R | 1 |
| George, J; Morrissey, I | 1 |
| Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H | 1 |
| Borner, K; Geerdes-Fenge, HF; Koeppe, P; Lode, H; Rau, M; Vöckler, J; Zix, JA | 1 |
| Cimbro, M; Dos Santos, C; Ferrara, A; Gialdroni Grassi, G | 1 |
| Charet, JC; Watine, J | 1 |
| Ishii, N; Nakajima, H; Sato, I; Sugita, Y | 1 |
| Igarashi, H; Kawahara, M; Matsubara, N; Matsunaga, T; Narita, H; Oishi, Y; Onodera, S; Takahata, M; Watanabe, Y; Yonezawa, M | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Deguchi, T; Ishihara, S; Kawada, Y; Nagata, O; Okezaki, E; Saito, I; Takahashi, Y; Yasuda, M | 1 |
| Dasgupta, MK; Larabie, M; Micetich, RG; Salama, S; Shishido, H; Singh, R | 1 |
| Cars, O; Löwdin, E; Odenholt, I | 1 |
| Kumar, D; Srivastava, BS; Srivastava, R | 1 |
| Ballow, CH; Deinhart, JA; Johnson, DM; Jones, RN; Schentag, JJ | 2 |
| Jones, RN; Pfaller, MA | 1 |
| Kim, S; Kim, SJ | 1 |
| Hayashi, Y; Ito, G; Takeyama, S | 1 |
| Adamantidis, MM; Bordet, R; Caron, JF; Dumotier, BM | 1 |
| Chuck, SK; Jung, R; Martin, SJ; Messick, CR; Meyer, JM; Pendland, SL | 1 |
| Aguado, AG; Marre, R; Mattina, R; Richard, MP | 1 |
| Choi, EC; Choi, KH; Kim, BK; Kim, JH; Kim, JW; Lee, JH | 1 |
| Domon, H; Miyazaki, S; Yamaguchi, K; Yoshizumi, S | 1 |
| Brookings, E; Gray, B; Nix, S; Robinson, A; Swiatlo, E; Waites, K | 1 |
| Engler, M; Holzgrabe, U; Rüsing, G; Sörgel, F | 1 |
| Drusano, G; Liu, QF; Liu, W; Louie, A; Madu, A; Mayers, M; Mian, U; Miller, MH; Perkins, R | 1 |
| Borner, K; Förster, C; Merker, HJ; Schwabe, R; Shakibaei, M; Stahlmann, R; Zippel, U | 1 |
| Kato, M; Shimoda, K | 1 |
| Hamanaka, H; Mizutani, H; Shimizu, M | 1 |
| Hoban, DJ; Karlowsky, JA; Zhanel, GG | 1 |
| Aubier, M; Geslin, P; Regamey, C; Vercken, JB; Verster, R | 1 |
| Young, LS | 1 |
| Azoulay-Dupuis, E; Bédos, JP; Moine, P; Muffat-Joly, M; Pocidalo, JJ; Vallée, E; Veber, B | 1 |
| Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D | 1 |
| Hirano, T; Iseki, K; Kobayashi, M; Miyazaki, K; Miyazaki, S; Sugawara, M; Takada, M; Tsuji, K | 1 |
| Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J | 1 |
| Bergmann, JS; Woods, GL | 1 |
| Dorian, M; Grellet, J; Saux, MC | 1 |
| Kusano, N; Taba, H | 1 |
| Dorr, MB; Ellison, W; Henry, D; Magner, DJ; Mansfield, DL; Sullivan, J; Talbot, GH | 1 |
| Bébéar, C; Bébéar, CM; Charron, A; de Barbeyrac, B; Dessus-Babus, S | 1 |
| Boyaka, PN; Carbon, C; Cormet-Boyaka, E; Huneau, JF; Mordrelle, A; Rubinstein, E; Tomé, D | 1 |
| Horgen, L; Legrand, E; Rastogi, N | 1 |
| Gandhi, TP; Modi, IA; Modi, RI; Mody, VD; Pandya, KK; Satia, MC | 1 |
| Kumon, H; Monden, K; Nasu, Y; Ohmori, H; Tsugawa, M | 1 |
| Blanco, MT; García, C; Gómez-García, AC; Hurtado, C; Morán, FJ; Pérez-Giraldo, C | 1 |
| Haraoka, M; Kobayashi, I; Nagafuji, T; Nakayama, H; Saika, T; Tanaka, M | 1 |
| Giamarellos-Bourboulis, EJ; Giamarellou, H; Grecka, P; Sambatakou, H | 1 |
| Biedenbach, DJ; Croco, MA; Doern, GV; Jones, RN; Pfaller, MA | 1 |
| Kamberi, M; Kotegawa, T; Nakamura, K; Nakano, S; Tsutsumi, K | 1 |
| Hirayama, F; Ikeda, Y; Kawakita, T; Kuroda, T; Moriguchi, A; Sakurai, N; Sano, M; Uemori, S; Yamamoto, K | 1 |
| Beach, ML; Doern, GV; Jones, RN; Pfaller, MA | 1 |
| Ohkubo, T; Sawada, Y; Suno, M; Urushidate, S; Yokoi, K; Yotsuyanagi, T | 1 |
| Biavasco, F; Mingoia, M; Montanari, MP; Prenna, M; Ripa, S; Varaldo, PE | 1 |
| Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR | 1 |
| Ramirez, J; Talbot, GH; Townsend, L; Unowsky, J; Zhang, H | 1 |
| Dorr, MB; Lipsky, BA; Magner, DJ; Talbot, GH | 1 |
| Akaki, T; Kajitani, H; Sato, K; Shishido, S; Tomioka, H | 1 |
| Ikeda, T; Kato, M; Okawara, S; Shimoda, K | 1 |
| Ahmed, S; Belal, F; El-Enany, NM; Ibrahim, F; Rizk, M | 1 |
| Ahr, HJ; Blotz, A; Blümel, J; Dubertret, L; Michel, L; Moysan, A; Vohr, HW | 1 |
| Andrews, JM; Boswell, FJ; Wise, R | 1 |
| Drexler, HG; Meyer, C; Uphoff, CC | 1 |
| Alovero, FL; Fisher, LM; Hamlyn, PJ; Manzo, RH; Pan, XS; Talens-Visconti, R | 1 |
| Hayakawa, H; Kawamura, Y; Miyazaki, M; Nagasawa, M; Nakamura, S; Nojima, Y | 1 |
| Fukuda, H; Kawamura, Y | 1 |
| Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T | 2 |
| Ameyama, S; Shinmura, Y; Takahata, M | 1 |
| Ono, C; Tanaka, M | 1 |
| Bao, L; Long, Y; Wu, YH; Xie, YX; Zeng, XW; Zhang, HD; Zhao, MC | 1 |
| Murakawa, GJ; Sable, D | 1 |
| Paramasivan, CN; Rahman, F; Sulochana, S | 1 |
| Abdel Ghani, NT; El Ries, MA; El-Shall, MA; Wassel, AA | 1 |
| Efthimiadou, EK; Karaliota, A; Katsaros, N; Psomas, G; Raptopoulou, CP; Sanakis, Y | 1 |
| Jain, M; Jayadev, S; Mishra, B; Patel, PR; Solanki, M; Soni, R; Srivastava, BK; Valani, D | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Baeyens, WR; Fei, G; He, L; Huang, C; Ouyang, J; Wang, Y | 1 |
| Efthimiadou, EK; Karaliota, A; Psomas, G | 1 |
| Kessissoglou, DP; Papadopoulos, AN; Perdih, F; Psomas, G; Skyrianou, KC; Turel, I | 1 |
| Kessissoglou, DP; Kljun, J; Polatoglou, E; Psomas, G; Tarushi, A; Turel, I | 1 |
17 review(s) available for sparfloxacin and carbostyril
| Article | Year |
|---|---|
Sparfloxacin and other new fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Enterobacteriaceae; Fluoroquinolones; Gram-Positive Bacteria; Humans; Mycoplasma; Quinolones | 1992 |
Treatment of tuberculosis in HIV infection.
Topics: AIDS-Related Opportunistic Infections; Animals; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Fluoroquinolones; Humans; Mice; Quinolones; Tuberculosis | 1992 |
[Significant role of newer quinolone antimicrobials in respiratory tract infection: focused on sparfloxacin].
Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Photosensitivity Disorders; Quinolones; Respiratory Tract Infections | 1994 |
Clinical pharmacokinetics of sparfloxacin.
Topics: Aging; Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Humans; Japan; Kidney Diseases; Quinolones | 1993 |
Sparfloxacin empirical therapy in community-acquired pneumonia. Results of a meta-analysis of 2 comparative studies.
Topics: Adult; Anti-Infective Agents; Community-Acquired Infections; Fluoroquinolones; Humans; Pneumonia, Bacterial; Pneumonia, Pneumococcal; Quinolones; Treatment Outcome | 1995 |
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; Renal Insufficiency | 1995 |
In-vitro activity of sparfloxacin in comparison with currently available antimicrobials against respiratory tract pathogens.
Topics: Anti-Infective Agents; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae | 1996 |
Pharmacokinetics of sparfloxacin in healthy volunteers and patients: a review.
Topics: Aged; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Humans; Liver Cirrhosis; Male; Quinolones; Reference Values; Renal Insufficiency; Tissue Distribution | 1996 |
Pharmacokinetic interactions related to the chemical structures of fluoroquinolones.
Topics: Aluminum Hydroxide; Animals; Anti-Infective Agents; Caffeine; Drug Interactions; Fluoroquinolones; Humans; Molecular Structure; Quinolones; Rats; Structure-Activity Relationship; Theophylline | 1996 |
A review of the penetration of sparfloxacin into the lower respiratory tract and sinuses.
Topics: Anti-Infective Agents; Female; Fluoroquinolones; Humans; Male; Paranasal Sinuses; Quinolones; Respiratory System | 1996 |
Overview of electrocardiographic and cardiovascular safety data for sparfloxacin. Sparfloxacin Safety Group.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cardiovascular System; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Electrocardiography; Female; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Randomized Controlled Trials as Topic | 1996 |
Sparfloxacin worldwide in vitro literature: isolate data available through 1994.
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1996 |
Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Safety; Syndrome | 1996 |
Sparfloxacin. A review of its antibacterial activity, pharmacokinetic properties, clinical efficacy and tolerability in lower respiratory tract infections.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Humans; Quinolones; Respiratory Tract Infections | 1997 |
New generations of quinolones: with particular attention to levofloxacin.
Topics: Anti-Infective Agents; Community-Acquired Infections; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Pneumonia; Quinolones | 1997 |
Levofloxacin and sparfloxacin: new quinolone antibiotics.
Topics: Absorption; Anti-Infective Agents; Bronchitis; Drug Interactions; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Pneumonia; Quinolones; Sinusitis; Skin Diseases; Urinary Tract Infections | 1998 |
Quinolones in dermatology.
Topics: Anti-Infective Agents; Area Under Curve; Bacterial Infections; Biological Availability; Ciprofloxacin; Fluoroquinolones; Humans; Intestinal Absorption; Microbial Sensitivity Tests; Nalidixic Acid; Quinolones; Skin Diseases; Structure-Activity Relationship | 2004 |
36 trial(s) available for sparfloxacin and carbostyril
| Article | Year |
|---|---|
Sparfloxacin in the treatment of males with urethritis.
Topics: Anti-Infective Agents; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Quinolones; Urethritis | 1992 |
Single-dose treatment of female acute uncomplicated cystitis.
Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Cefixime; Cefotaxime; Clinical Protocols; Colony Count, Microbial; Cystitis; Fluoroquinolones; Ofloxacin; Quinolones; Recurrence; Treatment Outcome; Urine | 1992 |
[Dose finding study of sparfloxacin in single-dose therapy for female acute uncomplicated cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Cystitis; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Middle Aged; Quinolones | 1992 |
[A trial of clinical application of sparfloxacin for treating mycobacterial infections].
Topics: Aged; Aged, 80 and over; Female; Fluoroquinolones; Humans; Male; Middle Aged; Mycobacterium Infections; Quinolones | 1995 |
Pharmacokinetics of sparfloxacin in humans after single oral administration at doses of 200, 400, 600, and 800 mg.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Fluoroquinolones; Humans; Male; Quinolones | 1994 |
The ocular penetration of oral sparfloxacin in humans.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Cataract Extraction; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Quinolones; Vitrectomy; Vitreous Body | 1994 |
Clinical trial of sparfloxacin for lepromatous leprosy.
Topics: Adolescent; Adult; Animals; Anti-Infective Agents; Antigens, Bacterial; Female; Fluoroquinolones; Foot; Glycolipids; Humans; Leprosy, Lepromatous; Male; Mice; Middle Aged; Mycobacterium leprae; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Quinolones; Spirometry | 1994 |
Multiple-dose pharmacokinetics of sparfloxacin and its influence on fecal flora.
Topics: Adult; Anti-Infective Agents; Biological Assay; Biological Availability; Blood Proteins; Chromatography, High Pressure Liquid; Double-Blind Method; Feces; Fluoroquinolones; Half-Life; Humans; Intestines; Male; Models, Biological; Protein Binding; Quinolones | 1994 |
[The dose-response study of sparfloxacin against skin and soft tissue structure infections in the field of surgery].
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Bacterial Infections; Connective Tissue Diseases; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Female; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Skin Diseases, Infectious | 1993 |
[Seminal plasma cytokines in nonbacterial prostatitis: changes following sparfloxacin treatment].
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Cytokines; Fluoroquinolones; Humans; Interleukin-1; Interleukin-6; Male; Middle Aged; Prostatitis; Quinolones; Semen; Tumor Necrosis Factor-alpha | 1995 |
Effect of ferrous sulfate on the absorption of sparfloxacin in healthy volunteers and rats.
Topics: Adult; Animals; Anti-Infective Agents; Cross-Over Studies; Double-Blind Method; Ferrous Compounds; Fluoroquinolones; Glucuronates; Half-Life; Humans; Male; Quinolones; Rats; Rats, Sprague-Dawley | 1995 |
Efficacy and safety of single oral dose sparfloxacin vs ciprofloxacin in acute gonococcal urethritis in males. A multicentre international study.
Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Fluoroquinolones; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Quinolones; Urethritis | 1995 |
Experimental and clinical studies of sparfloxacin in Mycoplasma pneumoniae infection.
Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Lung; Male; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1995 |
Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin.
Topics: Adolescent; Adult; Aged; Amoxicillin; Clavulanic Acids; Community-Acquired Infections; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Erythromycin; Female; Fluoroquinolones; Gastrointestinal Diseases; Humans; Male; Middle Aged; Pneumonia, Bacterial; Quinolones; Treatment Failure | 1995 |
Cimetidine does not alter sparfloxacin pharmacokinetics.
Topics: Adult; Anti-Infective Agents; Cimetidine; Cross-Over Studies; Double-Blind Method; Drug Interactions; Fluoroquinolones; Histamine H2 Antagonists; Humans; Male; Quinolones | 1995 |
Sparfloxacin for the treatment of community-acquired pneumonia: a pooled data analysis of two studies.
Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Clavulanic Acids; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Penicillins; Pneumonia, Bacterial; Quinolones; Streptococcus pneumoniae | 1996 |
Comparative efficacy of sparfloxacin in comparison with amoxycillin plus ofloxacin in the treatment of community-acquired pneumonia. French Study Group.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Penicillins; Pneumonia, Bacterial; Quinolones | 1996 |
Comparative safety and efficacy of sparfloxacin in the treatment of acute exacerbations of chronic obstructive pulmonary disease: a double-blind, randomised, parallel, multicentre study.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Clavulanic Acids; Double-Blind Method; Drug Therapy, Combination; Fluoroquinolones; Haemophilus influenzae; Humans; Lung Diseases, Obstructive; Middle Aged; Moraxella catarrhalis; Quinolones; Streptococcus pneumoniae | 1996 |
Sparfloxacin versus cefuroxime axetil in the treatment of acute purulent sinusitis. Sinusitis Study Group.
Topics: Acute Disease; Adult; Anti-Infective Agents; Cefuroxime; Cephalosporins; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Prodrugs; Quinolones; Sinusitis | 1996 |
Comparative efficacy and safety of single oral doses of sparfloxacin versus ciprofloxacin in the treatment of acute gonococcal urethritis in men.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Fluoroquinolones; Gonorrhea; Humans; International Cooperation; Male; Middle Aged; Quinolones; Urethritis | 1996 |
A comparative study of two different regimens of sparfloxacin versus doxycycline in the treatment of non-gonococcal urethritis in men.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Double-Blind Method; Doxycycline; Drug Administration Schedule; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Ureaplasma Infections; Ureaplasma urealyticum; Urethritis | 1996 |
Comparative efficacy of sparfloxacin versus ciprofloxacin in the treatment of complicated urinary tract infection.
Topics: Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Escherichia coli Infections; Female; Fluoroquinolones; Humans; International Cooperation; Male; Middle Aged; Quinolones; Urinary Tract Infections | 1996 |
Safety profile of sparfloxacin in the treatment of respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Clinical Trials, Phase III as Topic; Community-Acquired Infections; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pneumonia, Bacterial; Quinolones; Randomized Controlled Trials as Topic; Respiratory Tract Infections | 1996 |
Effects of a single oral dose of sparfloxacin on ventricular repolarization in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Double-Blind Method; Electrocardiography; Exercise Test; Fluoroquinolones; Heart Rate; Humans; Male; Quinolones; Ventricular Function | 1996 |
Pharmacokinetics of sparfloxacin and serum bactericidal activity against pneumococci.
Topics: Adult; Anti-Infective Agents; Female; Fluoroquinolones; Glucuronates; Half-Life; Humans; Male; Middle Aged; Penicillin Resistance; Quinolones; Serum Bactericidal Test; Streptococcus pneumoniae | 1996 |
Oral empiric treatment of community-acquired pneumonia. A multicenter, double-blind, randomized study comparing sparfloxacin with roxithromycin. The Scandinavian Sparfloxacin Study Group.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Pneumonia, Bacterial; Quinolones; Roxithromycin | 1996 |
[Urinary interleukin-6 and interleukin-8 in females with urethral syndrome].
Topics: Anti-Infective Agents; Female; Fluoroquinolones; Humans; Interleukin-6; Interleukin-8; Matched-Pair Analysis; Quinolones; Syndrome; Urethritis | 1997 |
Penetration of sparfloxacin and ciprofloxacin into alveolar macrophages, epithelial lining fluid, and polymorphonuclear leucocytes.
Topics: Anti-Infective Agents; Blood; Bronchoalveolar Lavage Fluid; Ciprofloxacin; Epithelium; Female; Fluoroquinolones; Humans; Leukocytes, Mononuclear; Lung; Macrophages, Alveolar; Male; Microbial Sensitivity Tests; Quinolones | 1997 |
Pharmacokinetics of sparfloxacin and interaction with cisapride and sucralfate.
Topics: Adult; Anti-Infective Agents; Anti-Ulcer Agents; Cisapride; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Fluoroquinolones; Humans; Male; Piperidines; Quinolones; Sucralfate | 1997 |
Sparfloxacin in the treatment of leprosy patients.
Topics: Adult; Anti-Infective Agents; Biopsy; Fluoroquinolones; Follow-Up Studies; Humans; Leprosy; Male; Quinolones; Retrospective Studies; Skin; Treatment Outcome | 1997 |
Once-daily sparfloxacin versus high-dosage amoxicillin in the treatment of community-acquired, suspected pneumococcal pneumonia in adults. Sparfloxacin European Study Group.
Topics: Adult; Amoxicillin; Anti-Infective Agents; Community-Acquired Infections; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Penicillins; Pneumonia, Pneumococcal; Quinolones; Streptococcus pneumoniae | 1998 |
Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chlamydia Infections; Chlamydophila pneumoniae; Chronic Disease; Cough; Double-Blind Method; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Moraxella catarrhalis; Neisseriaceae Infections; Ofloxacin; Placebos; Pneumococcal Infections; Quinolones; Sputum; Staphylococcal Infections; Treatment Outcome | 1998 |
Treatment of community-acquired acute uncomplicated urinary tract infection with sparfloxacin versus ofloxacin. The Sparfloxacin Multi Center UUTI Study Group.
Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Community-Acquired Infections; Female; Fluoroquinolones; Humans; Middle Aged; Ofloxacin; Quinolones; Recurrence; Treatment Outcome; Urinary Tract Infections | 1998 |
Prospective randomized comparative study of antibiotic prophylaxis in urethrocystoscopy and urethrocystography.
Topics: Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Cystoscopy; Female; Fleroxacin; Fluoroquinolones; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Urinary Tract Infections; Urography | 1998 |
Sparfloxacin pharmacokinetics in healthy volunteers: the influence of acidification and alkalinization.
Topics: Administration, Oral; Adult; Ammonium Chloride; Anti-Infective Agents; Antitubercular Agents; Chromatography, High Pressure Liquid; Fasting; Fluoroquinolones; Humans; Male; Oxidation-Reduction; Quinolones; Sodium Bicarbonate | 1998 |
Sparfloxacin versus clarithromycin in the treatment of community-acquired pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Community-Acquired Infections; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Pneumonia, Bacterial; Quinolones | 1999 |
260 other study(ies) available for sparfloxacin and carbostyril
| Article | Year |
|---|---|
[Clinical and bacteriological study of sparfloxacin on bacterial prostatitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacteria; Bacterial Infections; Drug Evaluation; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Prostatitis; Quinolones | 1992 |
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
CI-960 (PD127391 or AM-1091), sparfloxacin, WIN 57273, and isepamicin activity against clinical isolates of Mycobacterium avium-intracellularae complex, M. chelonae, and M. fortuitum.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gentamicins; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium chelonae; Nontuberculous Mycobacteria; Quinolones | 1992 |
In vitro and in vivo activities of sparfloxacin, other quinolones, and tetracyclines against Chlamydia trachomatis.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Quinolones; Tetracyclines | 1992 |
In vitro activities of three of the newer quinolones against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1992 |
In vitro activity of sparfloxacin (CI-978), a new broad-spectrum fluoroquinolone.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Norfloxacin; Quinolones | 1992 |
In vitro activity of sparfloxacin (AT-4140), a new quinolone agent, against invasive isolates from pediatric patients.
Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Infant; Infant, Newborn; Microbial Sensitivity Tests; Mutation; Quinolones | 1992 |
Antibacterial activity of sparfloxacin against experimental renal infections in mice.
Topics: Abscess; Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Fleroxacin; Fluoroquinolones; Half-Life; Kidney Diseases; Methicillin Resistance; Mice; Quinolones; Staphylococcal Infections | 1992 |
In-vitro activity of sparfloxacin, pefloxacin, ciprofloxacin and temafloxacin against clinical isolates of Acinetobacter spp.
Topics: Acinetobacter; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Pefloxacin; Quinolones | 1992 |
In vitro activity of sparfloxacin compared with those of five other quinolones.
Topics: Anti-Infective Agents; Fluoroquinolones; Hydrogen-Ion Concentration; Magnesium; Microbial Sensitivity Tests; Quinolones | 1992 |
In vitro activities of five quinolones against Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
Absence of bactericidal activity of sparfloxacin and ciprofloxacin under anaerobic conditions.
Topics: Anaerobiosis; Anti-Infective Agents; Ciprofloxacin; Clostridium; Fluoroquinolones; Pseudomonas; Quinolones | 1992 |
Activity of sparfloxacin against Mycobacterium leprae inoculated into footpads of nude mice.
Topics: Animals; Anti-Infective Agents; Female; Fluoroquinolones; Foot; Mice; Mice, Inbred BALB C; Mice, Nude; Mycobacterium leprae; Quinolones | 1992 |
[Extracellular and intracellular activity of sparfloxacin against Mycobacterium avium complex and Mycobacterium xenopi].
Topics: Acquired Immunodeficiency Syndrome; Antitubercular Agents; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; In Vitro Techniques; Mycobacterium; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Opportunistic Infections; Quinolones; Rifabutin; Rifamycins | 1992 |
[In vitro activity of sparfloxacin against mycoplasmas].
Topics: Culture Media; Dose-Response Relationship, Drug; Doxycycline; Drug Resistance, Microbial; Erythromycin; Fluoroquinolones; In Vitro Techniques; Mycoplasma; Mycoplasma fermentans; Mycoplasma pneumoniae; Ofloxacin; Quinolones; Ureaplasma urealyticum | 1992 |
Susceptibilities of penicillin-susceptible and -resistant strains of Streptococcus pneumoniae to RP 59500, vancomycin, erythromycin, PD 131628, sparfloxacin, temafloxacin, win 57273, ofloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Quinolones; Streptococcus pneumoniae; Vancomycin; Virginiamycin | 1992 |
Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells.
Topics: Anti-Infective Agents; Cells, Cultured; Fluoroquinolones; Humans; Neutrophils; Quinolones; Staphylococcus aureus | 1992 |
Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1992 |
Effects of the combination of lipopolysaccharide-specific monoclonal antibodies and sparfloxacin against Pseudomonas aeruginosa pneumonia in neutropenic mice.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Antibodies, Monoclonal; Cyclophosphamide; Drug Therapy, Combination; Female; Fluoroquinolones; Immunoglobulin G; Injections, Intravenous; Lipopolysaccharides; Lung; Mice; Mice, Inbred ICR; Neutropenia; Pneumonia; Pseudomonas Infections; Quinolones | 1992 |
Comparative in vitro activity of sparfloxacin (AT 4140, RP 64206--SPFX) against 275 multiresistant clinical isolates.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Lactams; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Staphylococcus | 1992 |
[A case of pulmonary atypical mycobacteriosis complicated with aplastic anemia, treated with surgical resection and postoperative sparfloxacin].
Topics: Anemia, Aplastic; Anti-Infective Agents; Antitubercular Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluoroquinolones; Humans; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Pneumonectomy; Quinolones; Tuberculosis, Pulmonary | 1992 |
Postantibiotic sub-MIC effects of vancomycin, roxithromycin, sparfloxacin, and amikacin.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolones; Roxithromycin; Streptococcus pneumoniae; Streptococcus pyogenes; Vancomycin | 1992 |
Determination of sparfloxacin in serum and urine by high-performance liquid chromatography.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Ofloxacin; Quinolones; Spectrometry, Fluorescence | 1992 |
[The dynamics of melanin-affinitive and non-affinitive antibacterial agents in the iris-ciliary body of rabbit eyes--comparative studies in pigmented and albino rabbits].
Topics: Animals; Anti-Infective Agents; Cefmenoxime; Ciliary Body; Female; Fluoroquinolones; Iris; Male; Melanins; Pigmentation; Quinolones; Rabbits | 1992 |
In vivo efficacy of a new fluoroquinolone, sparfloxacin, against penicillin-susceptible and -resistant and multiresistant strains of Streptococcus pneumoniae in a mouse model of pneumonia.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Female; Fluoroquinolones; Leukopenia; Lung; Mice; Mice, Inbred C57BL; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Species Specificity; Streptococcus pneumoniae | 1992 |
Sparfloxacin, ethambutol, and cortisol receptor inhibitor RU-40 555 treatment for disseminated Mycobacterium avium complex infection of normal C57BL/6 mice.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Feasibility Studies; Female; Fluoroquinolones; Glucocorticoids; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mifepristone; Mycobacterium avium; Quinolones; Receptors, Glucocorticoid; Spleen; Time Factors; Tuberculosis | 1992 |
Pharmacokinetics and inflammatory fluid penetration of sparfloxacin.
Topics: Administration, Oral; Adult; Blister; Exudates and Transudates; Fluoroquinolones; Humans; Inflammation; Intestinal Absorption; Male; Quinolones | 1992 |
Activities of various quinolone antibiotics against Mycobacterium leprae in infected mice.
Topics: Animals; Anti-Infective Agents; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Pefloxacin; Quinolones | 1992 |
The bactericidal activity of sparfloxacin.
Topics: Anti-Infective Agents; Escherichia coli; Fluoroquinolones; Oxygen; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
Effect of fenbufen on the pharmacokinetics of sparfloxacin in rats.
Topics: Algorithms; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Interactions; Fluoroquinolones; Injections, Intravenous; Male; Phenylbutyrates; Quinolones; Rats; Rats, Wistar | 1992 |
In vitro activity of sparfloxacin and other antimicrobial agents against genital pathogens.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Chlamydia trachomatis; Fluoroquinolones; Gardnerella vaginalis; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Quinolones; Species Specificity; Ureaplasma urealyticum | 1992 |
In vitro and in vivo evaluation of BMY 45243, a new 5-amino-naphthyridone derivative.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolones; Solubility | 1992 |
Bactericidal activities of single or multiple doses of various combinations of new antileprosy drugs and/or rifampin against M. leprae in mice.
Topics: Animals; Clarithromycin; Disease Models, Animal; Female; Fluoroquinolones; Foot; Hindlimb; Immunocompetence; Leprostatic Agents; Leprosy; Mice; Microbial Sensitivity Tests; Minocycline; Mycobacterium leprae; Ofloxacin; Quinolones; Rifampin | 1992 |
Activity of new quinolones against ciprofloxacin-resistant staphylococci.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus | 1991 |
Comparative in-vitro susceptibilities of Pseudomonas aeruginosa, Xanthomonas maltophilia, and Pseudomonas spp. to sparfloxacin (CI-978, AT-4140, PD131501) and reference antimicrobial agents.
Topics: Anti-Bacterial Agents; Drug Evaluation, Preclinical; Fluoroquinolones; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas aeruginosa; Quinolones; Xanthomonas | 1991 |
Bactericidal activity of sparfloxacin and ciprofloxacin under anaerobic conditions.
Topics: Anaerobiosis; Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1991 |
[Antimycobacterial activities of a new quinolone, sparfloxacin].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Microbial; Fluoroquinolones; Mice; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Quinolones; Tuberculosis | 1991 |
Role of protein D2 and lipopolysaccharide in diffusion of quinolones through the outer membrane of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Diffusion; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Fluoroquinolones; Imipenem; Immunoblotting; Lipopolysaccharides; Lysine; Protein Binding; Pseudomonas aeruginosa; Quinolones; Sugar Acids | 1991 |
[Effect of sparfloxacin on fecal microflora and its fecal concentration in patients with bacillary dysentery].
Topics: Adult; Anti-Infective Agents; Bacteria; Drug Evaluation; Dysentery, Bacillary; Feces; Female; Fluoroquinolones; Humans; Male; Quinolones | 1991 |
In vitro and in vivo activities of sparfloxacin (AT-4140) against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Tuberculosis | 1991 |
Synthesis of [carbonyl-14C]sparfloxacin.
Topics: Chromatography, Thin Layer; Fluoroquinolones; Hydrolysis; Indicators and Reagents; Isotope Labeling; Quinolones | 1991 |
Disposition and metabolism of [14C]sparfloxacin in the rat.
Topics: Animals; Autoradiography; Bile; Biotransformation; Enterohepatic Circulation; Feces; Female; Fluoroquinolones; Intestinal Absorption; Male; Milk; Pregnancy; Protein Binding; Quinolones; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
Disposition and metabolism of [14C]sparfloxacin after repeated administration in the rat.
Topics: Animals; Autoradiography; Bile; Feces; Fluoroquinolones; Glucuronates; Half-Life; Male; Quinolones; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
The penetration of sparfloxacin into human plasma and skin tissues.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Female; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Skin | 1991 |
[Clinical study of sparfloxacin, a new quinolone derivative, on urinary tract infection].
Topics: Adult; Anti-Infective Agents; Bacteria; Cystitis; Female; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Quinolones; Urinary Tract Infections | 1991 |
Pharmacokinetics of four fluoroquinolones in an animal model of infected lung.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Lung Diseases; Mice; Mice, Inbred Strains; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcus pneumoniae | 1991 |
In vitro activity of sparfloxacin and six reference antibiotics against gram-positive bacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacteria; Humans; Quinolones | 1991 |
Inhibitory effects of ciprofloxacin and sparfloxacin on DNA gyrase purified from fluoroquinolone-resistant strains of methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Superhelical; Drug Resistance, Microbial; Fluoroquinolones; Methicillin Resistance; Microbial Sensitivity Tests; Novobiocin; Quinolones; Staphylococcus aureus; Topoisomerase II Inhibitors | 1991 |
Mechanism of action of sparfloxacin against and mechanism of resistance in gram-negative and gram-positive bacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Probes; DNA, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mutation; Phenotype; Pseudomonas aeruginosa; Quinolones | 1991 |
Antimycobacterial spectrum of sparfloxacin and its activities alone and in association with other drugs against Mycobacterium avium complex growing extracellularly and intracellularly in murine and human macrophages.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Cells, Cultured; Drug Combinations; Fluoroquinolones; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Mycobacterium avium; Quinolones | 1991 |
Susceptibility of Mycoplasma pneumoniae to several new quinolones, tetracycline, and erythromycin.
Topics: Anti-Infective Agents; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Quinolones; Tetracycline | 1991 |
Susceptibilities of Mycoplasma hominis and Ureaplasma urealyticum to two new quinolones, sparfloxacin and WIN 57273.
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Ofloxacin; Quinolones; Tetracycline; Ureaplasma | 1991 |
[In vitro activities of newly developed quinolones, fleroxacin, lomefloxacin and sparfloxacin against Mycobacterium tuberculosis].
Topics: Anti-Infective Agents; Antitubercular Agents; Fleroxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1991 |
In-vitro activity of sparfloxacin, a new quinolone antimicrobial agent.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Blood Proteins; Ciprofloxacin; Fluoroquinolones; Humans; Lactams; Microbial Sensitivity Tests; Protein Binding; Quinolones | 1990 |
[Pharmacokinetic study of sparfloxacin in patients receiving regular hemodialysis].
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Fluoroquinolones; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Quinolones; Renal Dialysis | 1995 |
Comparison of sparfloxacin, temafloxacin, and ciprofloxacin for prophylaxis and treatment of experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Foreign Bodies; Guinea Pigs; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Rats; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 1995 |
Interactions between fluoroquinolones, Mg2+, DNA and DNA gyrase, studied by phase partitioning in an aqueous two-phase system and by affinity chromatography.
Topics: Animals; Anti-Infective Agents; Bacteria; Cattle; Chemical Phenomena; Chemistry, Physical; Chromatography, Affinity; Ciprofloxacin; Dextrans; DNA; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Fluoroquinolones; Magnesium; Polyethylene Glycols; Quinolones; Topoisomerase II Inhibitors; Water | 1994 |
Inhibition of HIV type 1 reverse transcriptase assay by nucleases produced by contaminating mycoplasmas.
Topics: Cell Line; Culture Techniques; Deoxyribonucleases; DNA Primers; DNA, Bacterial; Equipment Contamination; Fluoroquinolones; HIV Reverse Transcriptase; HIV-1; Humans; Mycoplasma; Mycoplasma fermentans; Polymerase Chain Reaction; Quinolones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Substrate Specificity; T-Lymphocytes | 1994 |
In vitro activity of tetracyclines, macrolides, quinolones, clindamycin and metronidazole against periodontopathic bacteria.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Clindamycin; Erythromycin; Fluoroquinolones; Metronidazole; Microbial Sensitivity Tests; Minocycline; Miocamycin; Naphthyridines; Ofloxacin; Porphyromonas gingivalis; Prevotella intermedia; Quinolones; Tetracycline | 1995 |
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis | 1995 |
A novel gyrB mutation in a fluoroquinolone-resistant clinical isolate of Salmonella typhimurium.
Topics: Anti-Infective Agents; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nalidixic Acid; Quinolones; Salmonella typhimurium | 1995 |
Systemic prophylaxis of experimental staphylococcal endophthalmitis: comparative efficacy of sparfloxacin, pefloxacin, imipenem, vancomycin, and amikacin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Eye; Eye Infections, Bacterial; Female; Fluoroquinolones; Imipenem; Pefloxacin; Quinolones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 1995 |
Activity of combinations of dapsone, rifampin, minocycline, clarithromycin, and sparfloxacin against M. leprae-infected mice.
Topics: Animals; Anti-Infective Agents; Clarithromycin; Dapsone; Drug Therapy, Combination; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Minocycline; Quinolones; Rifampin | 1995 |
Comparative in-vitro activities of the new quinolone, Bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, CI-960 and CI-990.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1993 |
Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Bites, Human; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Wound Infection | 1995 |
[In vitro activity of sparfloxacin against methicillin-resistant staphylococci].
Topics: Anti-Infective Agents; Fluoroquinolones; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Staphylococcal Infections; Staphylococcus | 1995 |
Parenteral sparfloxacin compared with ceftriaxone in treatment of experimental endocarditis due to penicillin-susceptible and -resistant streptococci.
Topics: Animals; Anti-Infective Agents; Ceftriaxone; Endocarditis, Bacterial; Female; Fluoroquinolones; Microbial Sensitivity Tests; Penicillin Resistance; Quinolones; Rats; Rats, Wistar; Streptococcal Infections | 1994 |
Effect of magnesium complexation by fluoroquinolones on their antibacterial properties.
Topics: Anti-Infective Agents; Bacteria; Fluoroquinolones; Magnesium; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pefloxacin; Quinolones | 1994 |
Intestinal elimination of sparfloxacin, fleroxacin, and ciprofloxacin in rats.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Ileum; Jejunum; Male; Quinolones; Rats; Rats, Sprague-Dawley | 1995 |
Suggested modifications for disk diffusion susceptibility testing criteria for levofloxacin and sparfloxacin following tests with a predictor panel of ciprofloxacin-resistant clinical isolates.
Topics: Ciprofloxacin; Diffusion; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Reproducibility of Results | 1995 |
In-vitro postantibiotic effect of sparfloxacin and ciprofloxacin against Pseudomonas aeruginosa and Enterococcus faecalis.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterococcus faecalis; Fluoroquinolones; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolones; Time Factors | 1994 |
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin | 1995 |
Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones.
Topics: Anaerobiosis; Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus aureus | 1995 |
Inhibition of the multiplication of Mycobacterium leprae in nude mice by intermittent administration of a new rifamycin derivative, 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin (KRM-1648) combined with sparfloxacin.
Topics: Administration, Oral; Animals; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Leprostatic Agents; Leprosy; Mice; Mice, Inbred BALB C; Mice, Nude; Mycobacterium leprae; Quinolones; Rifamycins | 1995 |
[Bactericidal activity of ciprofloxacin and sparfloxacin. Comparison with others active antibiotics against Pasteurella multocida].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cefpodoxime; Ceftizoxime; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; In Vitro Techniques; Pasteurella multocida; Quinolones | 1995 |
In vitro antimicrobial susceptibility of glycopeptide-resistant enterococci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Depsipeptides; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Fusidic Acid; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Novobiocin; Peptides, Cyclic; Quinolones; Teicoplanin; Vancomycin; Virginiamycin | 1995 |
Cross-resistance analysis for DU-6859a, a new fluoroquinolone, compared to six structurally similar compounds (ciprofloxacin, clinafloxacin, fleroxacin, levofloxacin, ofloxacin, and sparfloxacin).
Topics: Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fleroxacin; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
Study of comparative antipneumococcal activities of penicillin G, RP 59500, erythromycin, sparfloxacin, ciprofloxacin, and vancomycin by using time-kill methodology.
Topics: Anti-Infective Agents; Ciprofloxacin; Erythromycin; Fluoroquinolones; Kinetics; Microbial Sensitivity Tests; Penicillin G; Quinolones; Streptococcus pneumoniae; Time Factors; Vancomycin; Virginiamycin | 1994 |
Role of low-substituted hydroxypropylcellulose in dissolution and bioavailability of novel fine granule system for masking bitter taste.
Topics: Animals; Anti-Infective Agents; Biological Availability; Calorimetry, Differential Scanning; Cellulose; Excipients; Fluoroquinolones; Injections, Intravenous; Male; Powders; Quinolones; Rats; Rats, Wistar; Solubility; Taste | 1994 |
Effect of newer quinolones on the extra- and intra-cellular chemiluminescence response of human polymorphonuclear leucocytes.
Topics: Anti-Infective Agents; Ciprofloxacin; Extracellular Space; Fluoroquinolones; Humans; Luminescent Measurements; Neutrophils; Ofloxacin; Quinolones; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Rapid HPLC assay of clinafloxacin, fleroxacin, levofloxacin, sparfloxacin and tosufloxacin.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Fleroxacin; Fluoroquinolones; Humans; Naphthyridines; Quinolones; Reproducibility of Results | 1994 |
In vitro activities of enoxacin, enrofloxacin, sparfloxacin, and ciprofloxacin against Escherichia coli strains isolated from diarrheic lambs and kids.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diarrhea; Diarrhea, Infantile; Enoxacin; Enrofloxacin; Escherichia coli; Fluoroquinolones; Humans; Infant, Newborn; Microbial Sensitivity Tests; Quinolones; Sheep; Sheep Diseases | 1994 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
In vitro activity of CP-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1994 |
Assessment of the bactericidal activity of sparfloxacin, ofloxacin, levofloxacin, and other fluoroquinolones compared with selected agents of proven efficacy against Listeria monocytogenes.
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Listeria monocytogenes; Listeriosis; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination | 1994 |
In vitro activity of the new fluoroquinolone CP-99,219.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1994 |
Evaluations of the Etest for antimicrobial susceptibility testing of Legionella pneumophila, including validation of the imipenem and sparfloxacin strips.
Topics: Colony Count, Microbial; Evaluation Studies as Topic; Fluoroquinolones; Imipenem; Legionella pneumophila; Microbial Sensitivity Tests; Quinolones | 1994 |
Effects of antimicrobial and antineoplastic drugs on the uptake of sparfloxacin by human neutrophils.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Cells, Cultured; Drug Interactions; Fluoroquinolones; Humans; Neutrophils; Quinolones | 1994 |
In-vitro activity of four new fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones | 1994 |
Activity of levofloxacin in a murine model of tuberculosis.
Topics: Animals; Antitubercular Agents; Culture Media; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Stereoisomerism; Tuberculosis, Pulmonary | 1994 |
Increased activity of a new chlorofluoroquinolone, BAY y 3118, compared with activities of ciprofloxacin, sparfloxacin, and other antimicrobial agents against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1994 |
Protective effects of sparfloxacin in experimental pneumonia caused by Chlamydia pneumoniae in leukopenic mice.
Topics: Animals; Anti-Infective Agents; Chlamydia Infections; Chlamydophila pneumoniae; Female; Fluoroquinolones; Leukopenia; Lung; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pneumonia, Bacterial; Quinolones | 1994 |
Agar well diffusion assay testing of bacterial susceptibility to various antimicrobials in concentrations non-toxic for human cells in culture.
Topics: Anti-Infective Agents; Burns; Cells, Cultured; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mupirocin; Polymyxin B; Pseudomonas aeruginosa; Quinolones | 1994 |
[Therapeutic potential of sparfloxacin for preventing mycobacterial infections].
Topics: Anti-Infective Agents; Antitubercular Agents; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium Infections; Quinolones | 1994 |
Pharmacokinetics of sparfloxacin in patients with renal impairment.
Topics: Adult; Aged; Anti-Infective Agents; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Half-Life; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Quinolones; Spectrophotometry, Ultraviolet | 1994 |
In vitro and in vivo activities of sparfloxacin against Mycoplasma pneumoniae.
Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Levofloxacin; Lung; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1994 |
European Study Group on Antibiotic Breakpoints. Breakpoint determination: sparfloxacin.
Topics: Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Quinolones | 1994 |
Effect of sparfloxacin on Staphylococcus aureus adhesiveness and phagocytosis.
Topics: Animals; Anti-Infective Agents; Bacterial Adhesion; Fluoroquinolones; Guinea Pigs; Humans; In Vitro Techniques; Macrophages, Peritoneal; Microscopy, Electron, Scanning; Mouth Mucosa; Phagocytosis; Quinolones; Staphylococcal Infections; Staphylococcus aureus | 1994 |
In-vitro slime production by Staphylococcus epidermidis in presence of subinhibitory concentrations of ciprofloxacin, ofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus epidermidis | 1994 |
Rifabutin and sparfloxacin but not azithromycin inhibit binding of Mycobacterium avium complex to HT-29 intestinal mucosal cells.
Topics: Anti-Infective Agents; Azithromycin; Bacterial Adhesion; Fluoroquinolones; Humans; Intestinal Mucosa; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Quinolones; Rifabutin; Tumor Cells, Cultured | 1994 |
Different iris coloration and uptake of a fluoroquinolone agent into the iris ciliary body of rabbit eyes.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Ciliary Body; Eye Color; Female; Fluoroquinolones; Iris; Male; Melanins; Ophthalmic Solutions; Quinolones; Rabbits | 1994 |
Ciprofloxacin and sparfloxacin penetration into human brain tissue and their activity as antagonists of GABAA receptor of rat vagus nerve.
Topics: Animals; Anti-Infective Agents; Brain; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; GABA-A Receptor Antagonists; Male; Phenylacetates; Quinolones; Rats; Rats, Sprague-Dawley; Vagus Nerve | 1994 |
In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones | 1994 |
Comparative in vitro activities of new quinolones against coryneform bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Comparative activities of eight quinolones against members of the Bacteroides fragilis group.
Topics: Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Sparfloxacin and clinafloxacin alone or in combination with gentamicin for therapy of experimental ampicillin-resistant enterococcal endocarditis in rabbits.
Topics: Ampicillin Resistance; Animals; Anti-Infective Agents; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gentamicins; Gram-Positive Bacterial Infections; Quinolones; Rabbits; Random Allocation | 1993 |
Activity of sparfloxacin against Mycobacterium leprae measured by the proportional bactericidal test.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Fluoroquinolones; Leprosy; Mice; Mice, Nude; Microbial Sensitivity Tests; Mycobacterium leprae; Ofloxacin; Quinolones | 1993 |
Susceptibilities of Mycoplasma hominis, Mycoplasma pneumoniae, and Ureaplasma urealyticum to a new quinolone, OPC 17116.
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum | 1993 |
Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA-Directed DNA Polymerase; Enoxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Mutagenicity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolones; Salmonella typhimurium; SOS Response, Genetics; Species Specificity | 1993 |
[Compared antibacterial activity of a new fluoroquinolone, sparfloxacin (AT 4140, RP 64206) and four other fluoroquinolones against 332 strains of enteropathogen bacteria].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Helicobacter pylori; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1993 |
In vitro evaluation of activities of azithromycin, clarithromycin and sparfloxacin against Chlamydia trachomatis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Chlamydia trachomatis; Clarithromycin; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; In Vitro Techniques; Quinolones | 1993 |
Treatment of tuberculosis in HIV infection.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Fluoroquinolones; Humans; Quinolones; Tuberculosis | 1993 |
Mechanisms of quinolone resistance in clinical isolates: accumulation of sparfloxacin and of fluoroquinolones of various hydrophobicity, and analysis of membrane composition.
Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Bacterial Outer Membrane Proteins; Cell Membrane; Chemical Phenomena; Chemistry, Physical; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Magnesium; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus | 1993 |
In vitro activity of sparfloxacin compared with ciprofloxacin and ofloxacin against respiratory tract pathogens.
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1993 |
The in-vitro activity of Bay y 3118, a new chlorofluoroquinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Chlamydia; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Lactams; Microbial Sensitivity Tests; Quinolones; Species Specificity; Staphylococcus | 1993 |
Therapeutic effects of a human antiflagella monoclonal antibody in a neutropenic murine model of Pseudomonas aeruginosa pneumonia.
Topics: Animals; Anti-Infective Agents; Antibodies, Monoclonal; Bacteremia; Cell Movement; Female; Flagella; Fluoroquinolones; Humans; Lipopolysaccharides; Lung; Mice; Mice, Inbred ICR; Neutropenia; Opsonin Proteins; Phagocytosis; Pneumonia; Pseudomonas Infections; Quinolones; Serotyping | 1993 |
Powerful bactericidal activity of sparfloxacin (AT-4140) against Mycobacterium tuberculosis in mice.
Topics: Animals; Antitubercular Agents; Colony Count, Microbial; Drug Therapy, Combination; Female; Fluoroquinolones; Lung; Mice; Mycobacterium tuberculosis; Quinolones; Spleen; Tuberculosis, Pulmonary | 1993 |
Efficacy and ocular penetration of sparfloxacin in experimental streptococcal endophthalmitis.
Topics: Animals; Anti-Infective Agents; Endophthalmitis; Eye; Fluoroquinolones; Half-Life; Injections; Injections, Intramuscular; Pefloxacin; Quinolones; Rabbits; Staphylococcal Infections; Vitreous Body | 1993 |
Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Dioxolanes; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Topoisomerase II Inhibitors | 1993 |
Changes in adherence of respiratory pathogens to HEp-2 cells induced by subinhibitory concentrations of sparfloxacin, ciprofloxacin, and trimethoprim.
Topics: Anti-Infective Agents; Bacteria; Bacterial Adhesion; Carcinoma; Ciprofloxacin; Fluoroquinolones; Humans; Laryngeal Neoplasms; Quinolones; Respiratory Tract Infections; Trimethoprim; Tumor Cells, Cultured | 1993 |
Incomplete cross-resistance between ciprofloxacin and sparfloxacin in staphylococci, with a note on selection pressure due to clinical use of ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Methicillin Resistance; Microbial Sensitivity Tests; Phenotype; Quinolones; Staphylococcus aureus | 1993 |
Comparative susceptibilities of 173 aerobic and anaerobic bite wound isolates to sparfloxacin, temafloxacin, clarithromycin, and older agents.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Clarithromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Quinolones; Wound Infection | 1993 |
Sparfloxacin is more bactericidal than ofloxacin against Mycobacterium leprae in mice.
Topics: Animals; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Ofloxacin; Quinolones | 1993 |
Comparative antimycobacterial activities of the newly synthesized quinolone AM-1155, sparfloxacin, and ofloxacin.
Topics: Animals; Anti-Infective Agents; Female; Fluoroquinolones; Gatifloxacin; Intracellular Fluid; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium chelonae; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Piperazines; Quinolones | 1993 |
In vitro activity of sparfloxacin, ciprofloxacin, ofloxacin, and other antibiotics against bloodstream isolates of gram-positive cocci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
A novel fine granule system for masking bitter taste.
Topics: Animals; Anti-Infective Agents; Biological Availability; Capsules; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Dogs; Excipients; Fluoroquinolones; Humans; Male; Particle Size; Quinolones; Solubility; Tablets; Taste | 1993 |
Tentative interpretive criteria for disk diffusion susceptibility testing of sparfloxacin.
Topics: Anti-Infective Agents; Bacteria; Diffusion; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1993 |
Tentative criteria for confirming the in vitro susceptibilities of Haemophilus influenzae and Neisseria gonorrhoeae to two fluoroquinolones (sparfloxacin and levofloxacin), including quality control parameters.
Topics: Anti-Infective Agents; Fluoroquinolones; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quality Control; Quinolones | 1993 |
Activity of sparfloxacin on Staphylococcus epidermidis attached to plastic catheters.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Biocompatible Materials; Biofilms; Catheterization; Drug Therapy, Combination; Fluoroquinolones; Microbial Sensitivity Tests; Plastics; Polytetrafluoroethylene; Polyurethanes; Quinolones; Rifampin; Staphylococcus epidermidis | 1995 |
Cross-resistance analysis for clinafloxacin compared with ciprofloxacin, fleroxacin, ofloxacin, and sparfloxacin using a predictor panel of ciprofloxacin-resistant bacteria.
Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Activities of ciprofloxacin and sparfloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Streptococcus pneumoniae | 1995 |
In vitro susceptibility to ciprofloxacin of bacterial strains isolated from chronic otitis media and chronic sinusitis.
Topics: Adult; Anti-Infective Agents; Bacteria; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Otitis Media; Quinolones; Sinusitis | 1995 |
The antimicrobial activity of sparfloxacin, a new quinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones | 1995 |
In vitro and in vivo activities of sparfloxacin in Legionella infections.
Topics: Adult; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Erythromycin; Fluoroquinolones; Guinea Pigs; Humans; In Vitro Techniques; Legionella pneumophila; Legionnaires' Disease; Male; Microbial Sensitivity Tests; Neutrophils; Quinolones; Survival | 1995 |
In vitro activity of sparfloxacin against selected gram-negative blood culture isolates.
Topics: Anti-Infective Agents; Bacteremia; Culture Media; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillins; Quinolones | 1995 |
Comparative in vitro activity of BAY Y 3118 against selected species.
Topics: Anti-Infective Agents; Bacteria; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Absence of neuromuscular blocking activity of sparfloxacin.
Topics: Animals; Anti-Infective Agents; Diaphragm; Electric Stimulation; Fluoroquinolones; In Vitro Techniques; Male; Neuromuscular Blocking Agents; Phrenic Nerve; Quinolones; Rabbits; Rats; Rats, Wistar | 1995 |
Sparfloxacin secretion across Caco-2 cells involves a multidrug resistance-like mechanism.
Topics: Anti-Infective Agents; Caco-2 Cells; Cell Membrane Permeability; Drug Resistance, Multiple; Fluoroquinolones; Humans; Quinolones; Time Factors | 1995 |
Differences between albino and pigmented rabbit eyes in the intraocular pharmacokinetics of sparfloxacin.
Topics: Administration, Topical; Albinism, Ocular; Animals; Anti-Infective Agents; Ciliary Body; Eye; Eye Color; Female; Fluoroquinolones; Iris; Male; Melanins; Quinolones; Rabbits | 1995 |
Sparfloxacin, a new generation fluoroquinolone against S. pneumoniae respiratory infections.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pneumococcal Infections; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae; Survival | 1995 |
In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
Topics: Anti-Infective Agents; Azepines; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Effects of lomefloxacin and sparfloxacin on human platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Aged; Anti-Infective Agents; Collagen; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinolones; Reference Values | 1995 |
Comparative in-vitro activity of sparfloxacin and eight other antimicrobial agents against clinical isolates of non-tuberculous mycobacteria.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium; Quinolones | 1996 |
Activity of CP 99,219 (trovafloxacin) compared with ciprofloxacin, sparfloxacin, clinafloxacin, lomefloxacin and cefuroxime against ten penicillin-susceptible and penicillin-resistant pneumococci by time-kill methodology.
Topics: Anti-Infective Agents; Cefuroxime; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Penicillin Resistance; Quinolones; Streptococcus pneumoniae | 1996 |
Bactericidal kinetics and postantibiotic effect of sparfloxacin against selected species of respiratory pathogens.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Haemophilus influenzae; Humans; In Vitro Techniques; Klebsiella pneumoniae; Moraxella catarrhalis; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae | 1995 |
Determination of the minimal effective dosages of ofloxacin and sparfloxacin against M. leprae in the mouse foot pad system.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Foot; Mice; Mycobacterium leprae; Ofloxacin; Quinolones | 1996 |
In vitro and in vivo antibacterial activities of CS-940, a new 6-fluoro-8-difluoromethoxy quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Mice; Naphthyridines; Piperazines; Pneumonia, Bacterial; Quinolones | 1996 |
Effect of recombinant human gamma interferon on intracellular activities of antibiotics against Listeria monocytogenes in the human macrophage cell line THP-1.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cell Line; Fluoroquinolones; Humans; Interferon-gamma; Listeria monocytogenes; Macrophage Activation; Macrophages; Quinolones; Recombinant Proteins; Tetradecanoylphorbol Acetate; Virulence | 1996 |
[In vitro comparative activity (E test) of sparfloxacin and other 8 antimicrobial agents against bacteria isolated from patients with respiratory infections acquired in the community].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Quinolones; Respiratory Tract Infections | 1995 |
Comparative in-vitro activity of sparfloxacin against genital pathogens.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Female; Fluoroquinolones; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Quinolones; Ureaplasma urealyticum | 1996 |
Study design, methodology and statistical analyses in the clinical development of sparfloxacin.
Topics: Anti-Infective Agents; Double-Blind Method; Fluoroquinolones; Humans; International Cooperation; Multicenter Studies as Topic; Quinolones; Randomized Controlled Trials as Topic; Statistics as Topic | 1996 |
Sparfloxacin phototoxicity: potential photoaugmentation by ultraviolet A and B sources.
Topics: Animals; Anti-Infective Agents; Dermatitis, Phototoxic; DNA Damage; DNA, Single-Stranded; Fluoroquinolones; Male; Mice; Mice, Inbred BALB C; Quinolones; Ultraviolet Rays | 1996 |
[In vitro antibacterial activity of a new fluoroquinolone, sparfloxacin, against nosocomial bacteria, and concordance curve].
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Cross Infection; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Quinolones; Regression Analysis | 1996 |
Torsades de pointe probably related to sparfloxacin.
Topics: Anti-Infective Agents; Female; Fluoroquinolones; Humans; Mastoiditis; Middle Aged; Otitis Media; Pneumococcal Infections; Quinolones; Torsades de Pointes | 1996 |
Antipneumococcal activities of RP 59500 (quinupristin-dalfopristin), penicillin G, erythromycin, and sparfloxacin determined by MIC and rapid time-kill methodologies.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Penicillin G; Penicillin Resistance; Penicillins; Quinolones; Streptococcus pneumoniae; Time Factors; Virginiamycin | 1996 |
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media].
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolones | 1996 |
Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Media; Culture Media, Serum-Free; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Metals; Microbial Sensitivity Tests; Microscopy, Electron; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Urine | 1996 |
Mycoplasma orale infection affects K+ and Cl- currents in the HSG salivary gland cell line.
Topics: Antitubercular Agents; Calcium; Cell Line; Chloride Channels; Cytosol; Electric Conductivity; Fluoroquinolones; Humans; Hypotonic Solutions; Ionomycin; Mycoplasma Infections; Potassium Channels; Quinolones; Submandibular Gland | 1996 |
Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra.
Topics: Anti-Infective Agents; Antitubercular Agents; Base Sequence; Cell Wall; Cephaloridine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Permeability; Quinolones | 1996 |
Susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to a new quinolone, trovafloxacin (CP-99,219).
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Naphthyridines; Ofloxacin; Quinolones; Ureaplasma urealyticum | 1996 |
Intracellular activities of RP 59500 (quinupristin-dalfopristin) and sparfloxacin against Enterococcus faecium.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Enterococcus faecium; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Neutrophils; Quinolones; Vancomycin; Virginiamycin | 1996 |
Efficacy of sparfloxacin and autoradiographic diffusion pattern of [14C]Sparfloxacin in experimental Staphylococcus aureus joint prosthesis infection.
Topics: Animals; Anti-Infective Agents; Autoradiography; Bone and Bones; Diffusion; Fluoroquinolones; Joint Prosthesis; Microbial Sensitivity Tests; Pefloxacin; Prosthesis-Related Infections; Quinolones; Rabbits; Staphylococcal Infections | 1996 |
In vitro activity of trovafloxacin (CP-99,219), sparfloxacin, ciprofloxacin, and fleroxacin against respiratory pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Naphthyridines; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae | 1996 |
Comparative uptake of sparfloxacin and ciprofloxacin into human THP 1 monocytic cells.
Topics: Anti-Infective Agents; Cell Line; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Hypolipidemic Agents; Monocytes; Quinolones | 1996 |
In vitro activity of sparfloxacin against selected enterobacteriaceae and pseudomonaceae including Ps. pseudomallei (melioidosis).
Topics: Anti-Infective Agents; Burkholderia pseudomallei; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Pseudomonadaceae; Quinolones | 1995 |
Treatment of intracellular Mycobacterium avium complex infection by free and liposome-encapsulated sparfloxacin.
Topics: Animals; Anti-Infective Agents; Cell Line; Cell Survival; Fluoroquinolones; Humans; Indicators and Reagents; Liposomes; Macrophages; Mice; Mice, Inbred Strains; Mycobacterium avium-intracellulare Infection; Quinolones | 1996 |
A case of relapsed leprosy successfully treated with sparfloxacin.
Topics: Adult; Anti-Infective Agents; Fluoroquinolones; Humans; Leprosy, Lepromatous; Male; Quinolones; Recurrence; Remission Induction | 1996 |
In vitro susceptibility of anaerobes to quinolones in the United States.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial; Evaluation Studies as Topic; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Quinolones; United States | 1996 |
Effect of paclitaxel alone or in combination on the intracellular penetration and activity of quinolones in human neutrophils.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cisplatin; Doxorubicin; Fluoroquinolones; Humans; Levofloxacin; Neutrophils; Ofloxacin; Paclitaxel; Quinolones; Staphylococcus aureus | 1996 |
Comparative activities of new fluoroquinolones, alone or in combination with amoxicillin, trimethoprim-sulfamethoxazole, or rifampin, against intracellular Listeria monocytogenes.
Topics: Amoxicillin; Anti-Infective Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Fluoroquinolones; HeLa Cells; Humans; Levofloxacin; Listeria monocytogenes; Ofloxacin; Quinolones; Rifampin; Sulfamethoxazole; Trimethoprim | 1997 |
Effect of antioxidants, anti-inflammatory drugs, and histamine antagonists on sparfloxacin-induced phototoxicity in mice.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonic Acid; Dermatitis, Phototoxic; Female; Fluoroquinolones; Histamine Antagonists; Histamine Release; Mast Cells; Mice; Mice, Inbred BALB C; Photosensitivity Disorders; Quinolones; Reactive Oxygen Species; Retinal Degeneration; Skin; Ultraviolet Rays | 1996 |
Evidence for a passive diffusion mechanism for sparfloxacin uptake at the brush-border membrane of the human intestinal cell-line Caco-2.
Topics: Anti-Infective Agents; Caco-2 Cells; Diffusion; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Microvilli; Quinolones | 1997 |
Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Mutation; Polymerase Chain Reaction; Quinolones; Streptococcus pneumoniae | 1997 |
Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones.
Topics: Acinetobacter; Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Pefloxacin; Quinolones | 1996 |
Efficacy of combined clarithromycin and sparfloxacin therapy in a patient with discitis: due to Mycobacterium xenopi.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Discitis; Drug Therapy, Combination; Fluoroquinolones; Humans; Lumbar Vertebrae; Male; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Quinolones; Sacrum | 1997 |
Multicentre in-vitro evaluation of the susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis to ciprofloxacin, clarithromycin, co-amoxiclav and sparfloxacin.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Clavulanic Acids; Drug Evaluation; Drug Therapy, Combination; Fluoroquinolones; Haemophilus influenzae; Microbial Sensitivity Tests; Moraxella catarrhalis; Quinolones; Streptococcus pneumoniae | 1997 |
The new antibiotics, 1997.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Erythromycin; Fluoroquinolones; Humans; Macrolides; Meropenem; Penicillins; Piperacillin; Quinolones; Thienamycins | 1997 |
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones.
Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation | 1997 |
Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Fluoroquinolones; Novobiocin; Ofloxacin; Quinolones; Staphylococcus aureus; Substrate Specificity; Topoisomerase II Inhibitors | 1996 |
High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA.
Topics: 4-Quinolones; Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Mutation; Pefloxacin; Quinolones; Sequence Analysis, DNA; Streptococcus pneumoniae; Transformation, Genetic | 1996 |
Sparfloxacin and levofloxacin.
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Drug Eruptions; Fluoroquinolones; Gastrointestinal Diseases; Humans; Levofloxacin; Ofloxacin; Photosensitivity Disorders; Pneumonia; Quinolones | 1997 |
The activity of the methylpiperazinyl fluoroquinolone CG 5501: a comparison with other fluoroquinolones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteroides fragilis; Chlamydia; Ciprofloxacin; Clarithromycin; Doxycycline; Enterobacter; Erythromycin; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Haemophilus influenzae; Microbial Sensitivity Tests; Naphthyridines; Piperazines; Pseudomonas aeruginosa; Quinolones; Streptococcus pneumoniae | 1997 |
In-vitro and in-vivo activities of DW-116, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Enterococcus faecalis; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methicillin Resistance; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus | 1997 |
Is Escherichia coli ATCC 25922 useful for monitoring broth microdilution tests of fluoroquinolones?
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Reproducibility of Results | 1997 |
Comparative in vitro activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against 387 aerobic and anaerobic bite wound isolates.
Topics: Animals; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Cats; Ciprofloxacin; Dogs; Fluoroquinolones; Haplorhini; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Swine; Wound Infection | 1997 |
Antimicrobial activity and spectrum of sparfloxacin tested against erythromycin-resistant Streptococcus pneumoniae isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Streptococcus pneumoniae | 1996 |
Activity of rifabutin, clarithromycin, ethambutol, sparfloxacin and amikacin, alone and in combination, against Mycobacterium avium complex in human macrophages.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Quinolones; Rifabutin | 1996 |
The bactericidal activity of levofloxacin compared with ofloxacin, D-ofloxacin, ciprofloxacin, sparfloxacin and cefotaxime against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Cefotaxime; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1997 |
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Time-kill study of the activity of trovafloxacin compared with ciprofloxacin, sparfloxacin, metronidazole, cefoxitin, piperacillin and piperacillin/tazobactam against six anaerobes.
Topics: Anti-Infective Agents; Bacteroides; Bacteroides fragilis; Cefoxitin; Ciprofloxacin; Clostridium perfringens; Fluoroquinolones; Fusobacterium; Gram-Negative Anaerobic Bacteria; Metronidazole; Microbial Sensitivity Tests; Naphthyridines; Penicillanic Acid; Peptostreptococcus; Piperacillin; Prevotella melaninogenica; Quinolones; Tazobactam | 1997 |
Effect of different combinations of sparfloxacin, oxacillin, and fosfomycin against methicillin-resistant staphylococci.
Topics: Anti-Infective Agents; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Fosfomycin; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Quinolones; Staphylococcus | 1997 |
[Bactericidal activity of quinolones (including sparfloxacin) against Enterococcus; in vitro antagonisms with gentamicin].
Topics: Anti-Infective Agents; Drug Antagonism; Drug Therapy, Combination; Enterococcus; Fluoroquinolones; Gentamicins; In Vitro Techniques; Microbial Sensitivity Tests; Phenotype; Quinolones | 1997 |
Antibacterial activity of quinolones against coagulase-negative staphylococci and the quinolone resistance-determining region of the gyrA genes from six species.
Topics: Anti-Infective Agents; Base Sequence; Coagulase; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Naphthyridines; Polymerase Chain Reaction; Quinolones; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Staphylococcus; Staphylococcus epidermidis | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
In-vitro antimicrobial activity of HSR-903, a new fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae with quinolone resistance-associated alterations in GyrA and ParC.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Quinolones; Urethritis | 1997 |
The effects of macrolide and quinolone antibiotics in methicillin-resistant Staphylococcus aureus biofilm growth.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Catheterization; Ciprofloxacin; Erythromycin; Fluoroquinolones; Methicillin Resistance; Quinolones; Staphylococcus aureus | 1997 |
Studies of the killing kinetics of benzylpenicillin, cefuroxime, azithromycin, and sparfloxacin on bacteria in the postantibiotic phase.
Topics: Anti-Bacterial Agents; Azithromycin; Cefuroxime; Drug Administration Schedule; Drug Resistance, Microbial; Fluoroquinolones; Haemophilus influenzae; Kinetics; Microbial Sensitivity Tests; Penicillin G; Quinolones; Streptococcus pyogenes | 1997 |
Recombinant Mycobacterium aurum expressing Escherichia coli beta-galactosidase in high throughput screening of antituberculosis drugs.
Topics: Antitubercular Agents; beta-Galactosidase; DNA, Recombinant; Drug Evaluation, Preclinical; Escherichia coli; Fluoroquinolones; Lac Operon; Microbial Sensitivity Tests; Mycobacterium; Quinolones; Recombinant Proteins | 1997 |
Comparative in vitro assessment of sparfloxacin activity and spectrum using results from over 14,000 pathogens isolated at 190 medical centers in the USA. SPAR Study Group.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Haemophilus; Humans; In Vitro Techniques; Klebsiella; Moraxella catarrhalis; Oxacillin; Quinolones; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae; United States | 1997 |
Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcal Infections; Streptococcus; Streptococcus pneumoniae | 1997 |
Abnormal proteins enhance stress-induced cell death.
Topics: Anti-Infective Agents; Bacterial Proteins; Chaperonins; Enzyme Stability; Escherichia coli; Fluoroquinolones; Methionine-tRNA Ligase; Models, Molecular; Mutation; Ofloxacin; Peptide Fragments; Protein Conformation; Quinolones | 1998 |
[Clinical study on sparfloxacin (SPFX) in the treatment of mycoplasmal pneumonia and penetration of SPFX to the pneumonic lesion].
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Bacterial Translocation; Bronchoalveolar Lavage Fluid; Female; Fluoroquinolones; Humans; Male; Middle Aged; Mycoplasma; Pneumonia, Mycoplasma; Quinolones | 1998 |
The effect of antibiotic exposure on adherence to neutrophils of Enterococcus faecium resistant to phagocytosis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Adhesion; Drug Resistance, Microbial; Enterococcus faecium; Fluoroquinolones; Humans; Neutrophils; Phagocytosis; Quinolones; Virginiamycin | 1997 |
Sparfloxacin but not levofloxacin or ofloxacin prolongs cardiac repolarization in rabbit Purkinje fibers.
Topics: Action Potentials; Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Male; Ofloxacin; Purkinje Fibers; Quinolones; Rabbits; Stereoisomerism | 1998 |
Sensitivity to sparfloxacin and other antibiotics, of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis strains isolated from adult patients with community-acquired lower respiratory tract infections: a European multicentre study.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Microbial; Europe; Fluoroquinolones; Haemophilus influenzae; Humans; Moraxella catarrhalis; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae | 1998 |
In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1998 |
[Sparfloxacin].
Topics: Anti-Infective Agents; Antitubercular Agents; Fluoroquinolones; Quinolones | 1998 |
In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections; Streptococcal Infections; Streptococcus pneumoniae | 1998 |
Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by Etest.
Topics: Anti-Infective Agents; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1998 |
Defluorinated sparfloxacin as a new photoproduct identified by liquid chromatography coupled with UV detection and tandem mass spectrometry.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Fluoroquinolones; Mass Spectrometry; Photochemistry; Quinolones | 1998 |
In vitro evaluation of sparfloxacin activity and spectrum against 24,940 pathogens isolated in the United States and Canada, the final analysis.
Topics: Anti-Infective Agents; Canada; Drug Evaluation, Preclinical; Enterobacteriaceae; Fluoroquinolones; Haemophilus; Humans; Klebsiella; Microbial Sensitivity Tests; Moraxella catarrhalis; Penicillin Resistance; Penicillins; Quinolones; Staphylococcus aureus; United States | 1998 |
Pharmacokinetics of sparfloxacin in the serum and vitreous humor of rabbits: physicochemical properties that regulate penetration of quinolone antimicrobials.
Topics: Animals; Anti-Infective Agents; Eye; Fluoroquinolones; Male; Probenecid; Quinolones; Rabbits; Renal Agents; Vitreous Body | 1998 |
Chondrotoxicity and toxicokinetics of sparfloxacin in juvenile rats.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Immunohistochemistry; Knee Joint; Quinolones; Rats; Rats, Wistar | 1998 |
Involvement of reactive oxygen species, protein kinase C, and tyrosine kinase in prostaglandin E2 production in Balb/c 3T3 mouse fibroblast cells by quinolone phototoxicity.
Topics: 3T3 Cells; Animals; Anti-Infective Agents; Cell Membrane; Dinoprostone; Fluoroquinolones; Interleukin-1; Mice; Mice, Inbred BALB C; Photosensitizing Agents; Protein Kinase C; Protein-Tyrosine Kinases; Quinolones; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 1998 |
Sparfloxacin-induced photosensitivity and the occurrence of a lichenoid tissue reaction after prolonged exposure.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Drug Eruptions; Female; Fluoroquinolones; HLA-DR Antigens; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lichenoid Eruptions; Male; Middle Aged; Photosensitivity Disorders; Quinolones; Skin | 1998 |
In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Vancomycin | 1998 |
A new fluoroquinolone for community-acquired pneumonia.
Topics: Anti-Infective Agents; Community-Acquired Infections; Fluoroquinolones; Humans; Pneumonia, Pneumococcal; Quinolones | 1998 |
Pharmacodynamic activities of ciprofloxacin and sparfloxacin in a murine pneumococcal pneumonia model: relevance for drug efficacy.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Quinolones; Streptococcus pneumoniae | 1998 |
Ionic-diffusion potential-dependent transport of a new quinolone, sparfloxacin, across rat intestinal brush-border membrane.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Hydrogen-Ion Concentration; Intestinal Absorption; Ion Transport; Male; Membrane Potentials; Microvilli; Quinolones; Rats; Rats, Wistar | 1998 |
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones | 1998 |
In vitro activity of antimicrobial combinations against clinical isolates of susceptible and resistant Mycobacterium tuberculosis.
Topics: Amoxicillin; Antitubercular Agents; Clavulanic Acid; Drug Combinations; Drug Interactions; Evaluation Studies as Topic; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinolones; Rifabutin | 1998 |
Uptake of fluoroquinolones in human monocytes isolated from peripheral blood.
Topics: Anti-Infective Agents; Cell Adhesion; Cell Separation; Ciprofloxacin; Flow Cytometry; Fluoroquinolones; Humans; Monocytes; Ofloxacin; Quinolones | 1998 |
Sparfloxacin resistance in clinical isolates of Streptococcus pneumoniae: involvement of multiple mutations in gyrA and parC genes.
Topics: Amino Acid Sequence; Anti-Infective Agents; Base Sequence; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Fluoroquinolones; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Quinolones; Streptococcus pneumoniae | 1998 |
Sequencing of gyrase and topoisomerase IV quinolone-resistance-determining regions of Chlamydia trachomatis and characterization of quinolone-resistant mutants obtained In vitro.
Topics: Amino Acid Sequence; Anti-Infective Agents; Base Sequence; Chlamydia trachomatis; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Molecular Sequence Data; Mutation; Ofloxacin; Quinolones | 1998 |
Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors.
Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Fluoroquinolones; Humans; Intestinal Mucosa; Quinolones; Rats; Vinblastine | 1998 |
Postantibiotic effect of amikacin, rifampin, sparfloxacin, clofazimine and clarithromycin against Mycobacterium avium.
Topics: Amikacin; Anti-Bacterial Agents; Bacteriological Techniques; Clarithromycin; Clofazimine; Colony Count, Microbial; Fluoroquinolones; Humans; Mycobacterium avium Complex; Quinolones; Rifampin; Serum Bactericidal Test | 1997 |
High performance thin-layer chromatographic method for the determination of sparfloxacin in human plasma and its use in pharmacokinetic studies.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Antitubercular Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Male; Quinolones | 1998 |
Phagocytosis and killing of slime-producing Staphylococcus epidermidis bypolymorphonuclear leukocytes. Effects of sparfloxacin.
Topics: Aerobiosis; Anti-Infective Agents; Bacterial Adhesion; Biofilms; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Neutrophils; Phagocytosis; Quinolones; Staphylococcus epidermidis | 1998 |
Analysis of quinolone resistance mechanisms in a sparfloxacin-resistant clinical isolate of Neisseria gonorrhoeae.
Topics: Adult; Anti-Infective Agents; Drug Resistance, Microbial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Polymerase Chain Reaction; Quinolones; Treatment Failure | 1998 |
In vitro activity of quinupristin/dalfopristin and newer quinolones combined with gentamicin against resistant isolates of Enterococcus faecalis and Enterococcus faecium.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gentamicins; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Virginiamycin | 1998 |
In-vitro activities of gatifloxacin, sparfloxacin and trovafloxacin against 103 strains of Legionella spp.
Topics: Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Humans; Legionella; Legionella pneumophila; Legionellosis; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1998 |
Synthesis and structure-activity relationships of 7-(2-aminoalkyl)morpholinoquinolones as anti-Helicobacter pylori agents.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Drug Stability; Fluoroquinolones; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Indicators and Reagents; Microbial Sensitivity Tests; Molecular Structure; Naphthyridines; Ofloxacin; Quinolones; Solutions; Structure-Activity Relationship; Ultraviolet Rays | 1998 |
Antimicrobial activity of gatifloxacin tested against 1676 strains of ciprofloxacin-resistant gram-positive cocci isolated from patient infections in North and South America.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteriological Techniques; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Naphthyridines; North America; Quinolones; South America | 1998 |
A study of the concentration of orally administered sparfloxacin found in exudates from suture wounds beneath occlusive dressings.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Infective Agents; Chromatography, High Pressure Liquid; Dermatologic Surgical Procedures; Exudates and Transudates; Female; Fluoroquinolones; Follow-Up Studies; Humans; Male; Middle Aged; Occlusive Dressings; Quinolones; Skin; Surgical Wound Infection; Sutures | 1998 |
Antistaphylococcal and antistreptococcal killing kinetics of ciprofloxacin, ofloxacin, sparfloxacin, and trovafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pneumoniae; Streptococcus pyogenes | 1998 |
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin | 1999 |
Safety profile of sparfloxacin, a new fluoroquinolone antibiotic.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Bronchitis; Clinical Trials, Phase III as Topic; Community-Acquired Infections; Data Interpretation, Statistical; Female; Fluoroquinolones; Heart Rate; Humans; Male; Middle Aged; Photosensitivity Disorders; Pneumonia, Bacterial; Quinolones; Sinusitis; Skin Diseases, Bacterial | 1999 |
Comparative antimicrobial activities of the newly synthesized quinolone WQ-3034, levofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: 4-Quinolones; Aminopyridines; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Rifamycins | 2000 |
Possible relationship between phototoxicity and photodegradation of sitafloxacin, a quinolone antibacterial agent, in the auricular skin of albino mice.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Photolysis; Quinolones; Time Factors; Ultraviolet Rays | 2000 |
Voltammetric analysis of certain 4-quinolones in pharmaceuticals and biological fluids.
Topics: Anti-Infective Agents; Electrochemistry; Enrofloxacin; Fleroxacin; Fluoroquinolones; Oxidation-Reduction; Quinolones | 2000 |
Analyses of cutaneous fluoroquinolones photoreactivity using the integrated model for the differentiation of skin reactions.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents; Biomarkers; Cell Membrane; Enoxacin; Female; Fluoroquinolones; Irritants; Mice; Models, Biological; Ofloxacin; Phenotype; Photosensitizing Agents; Quinolones; Skin | 2000 |
Comparison of the in vitro activities of BMS-284756 and four fluoroquinolones against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Moxifloxacin; Norfloxacin; Quinolines; Quinolones; Streptococcus pneumoniae | 2001 |
Elimination of mycoplasma from leukemia-lymphoma cell lines using antibiotics.
Topics: Algorithms; Anti-Bacterial Agents; Anti-Infective Agents; Cell Culture Techniques; Ciprofloxacin; Culture Media; Diterpenes; Drug Resistance; Drug Resistance, Multiple, Bacterial; Enrofloxacin; Fluoroquinolones; Humans; Leukemia; Lymphoma; Minocycline; Mycoplasma; Quinolones; Suspensions; Tumor Cells, Cultured | 2002 |
Small-colony mutants of Staphylococcus aureus allow selection of gyrase-mediated resistance to dual-target fluoroquinolones.
Topics: Anti-Infective Agents; Coagulase; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Microbial; Fluoroquinolones; Hemin; Microbial Sensitivity Tests; Mutation; Phenotype; Quinolones; Staphylococcus aureus; Thymidine; Vitamin K 3 | 2002 |
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Female; Fluoroquinolones; Guinea Pigs; Nalidixic Acid; Ofloxacin; Oxazines; Quinolones; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 2002 |
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins | 2002 |
Reliability of phototoxic tests of fluoroquinolones in vitro.
Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Micronucleus Tests; Norfloxacin; Quinolones; Rats; Rats, Wistar; Ultraviolet Rays | 2003 |
Inhibitory activities of quinolones against DNA gyrase of Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Chlamydophila pneumoniae; DNA Gyrase; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Indoles; Levofloxacin; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Topoisomerase II Inhibitors | 2003 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays | 2004 |
[Study on the gene mutation of quinolone-resistant Mycobacterium tuberculosis isolated from Sichuan Province].
Topics: Antibiotics, Antitubercular; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Mutation; Mycobacterium tuberculosis; Ofloxacin; Polymorphism, Single-Stranded Conformational; Quinolones | 2004 |
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Quinolones; Sampling Studies; Sensitivity and Specificity | 2005 |
Electrochemical adsorptive behavior of some fluoroquinolones at carbon paste electrode.
Topics: Adsorption; Anti-Infective Agents; Carbon; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Fluoroquinolones; Gatifloxacin; Quinolones | 2005 |
Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin.
Topics: Anti-Bacterial Agents; Copper; Crystallography, X-Ray; DNA; Fluoroquinolones; Molecular Structure; Organometallic Compounds; Quinolones; Spectrophotometry | 2006 |
Synthesis and antibacterial activity of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Microbial Sensitivity Tests; Models, Chemical; Molecular Conformation; Pyridines; Quinolones | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive.
Topics: Buffers; Electrophoresis, Capillary; Fleroxacin; Fluoroquinolones; Gatifloxacin; Nanoparticles; Ofloxacin; Oxazines; Quinolones; Silicon Dioxide | 2009 |
Metal complexes of the third-generation quinolone antimicrobial drug sparfloxacin: Structure and biological evaluation.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cattle; DNA; Electrochemical Techniques; Ethidium; Fluorescent Dyes; Fluoroquinolones; Humans; Isomerism; Metals; Microbial Sensitivity Tests; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Quinolones; Serum Albumin | 2010 |
Nickel-quinolones interaction. Part 5-Biological evaluation of nickel(II) complexes with first-, second- and third-generation quinolones.
Topics: Animals; Cattle; DNA; Fluoroquinolones; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Nickel; Oxolinic Acid; Quinolones; Serum Albumin; Serum Albumin, Bovine | 2011 |
Interaction of Zn(II) with quinolone drugs: structure and biological evaluation.
Topics: Animals; Anti-Bacterial Agents; Cattle; Coordination Complexes; Crystallography, X-Ray; DNA; Fluoroquinolones; Humans; Levofloxacin; Models, Molecular; Ofloxacin; Protein Binding; Quinolones; Serum Albumin; Serum Albumin, Bovine; Zinc | 2011 |