spa-s-132 and steffimycin

spa-s-132 has been researched along with steffimycin* in 1 studies

Other Studies

1 other study(ies) available for spa-s-132 and steffimycin

Article	Year
Screening of antibiotics preferentially active against ras oncogene-expressed cells. The Journal of antibiotics, 1990, Volume: 43, Issue:11 During the course of in vitro screening of agents which are preferentially active against ras oncogene-expressed cells, a new anthracycline (identified as 2-demethylsteffimycin D) and a heptaene (possibly a new member of partricins) were isolated from microbial fermentation broths. Among known compounds tested, 5-fluorouracil, 5-fluorodeoxyuridine and oxanosine showed high selectivity towards ras oncogene-expressed cells. Topics: Animals; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cell Line; Cell Line, Transformed; Chromatography, High Pressure Liquid; Gene Expression Regulation, Neoplastic; Genes, ras; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Polyenes; Streptomyces	1990

Article

Year

Screening of antibiotics preferentially active against ras oncogene-expressed cells.

The Journal of antibiotics, 1990, Volume: 43, Issue:11

During the course of in vitro screening of agents which are preferentially active against ras oncogene-expressed cells, a new anthracycline (identified as 2-demethylsteffimycin D) and a heptaene (possibly a new member of partricins) were isolated from microbial fermentation broths. Among known compounds tested, 5-fluorouracil, 5-fluorodeoxyuridine and oxanosine showed high selectivity towards ras oncogene-expressed cells.

Topics: Animals; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cell Line; Cell Line, Transformed; Chromatography, High Pressure Liquid; Gene Expression Regulation, Neoplastic; Genes, ras; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Polyenes; Streptomyces

1990