Page last updated: 2024-09-03

soyasaponin bb and oleanolic acid

soyasaponin bb has been researched along with oleanolic acid in 54 studies

Compound Research Comparison

Studies (soyasaponin bb)	Trials (soyasaponin bb)	Recent Studies (post-2010) (soyasaponin bb)	Studies (oleanolic acid)	Trials (oleanolic acid)	Recent Studies (post-2010) (oleanolic acid)
65	1	28	4,169	31	2,404

Protein Interaction Comparison

Protein	Taxonomy	oleanolic acid (IC50)
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	2.045
Phospholipase A2	Homo sapiens (human)	3
DNA polymerase beta	Homo sapiens (human)	6.8667
DNA polymerase beta	Rattus norvegicus (Norway rat)	5.6
Receptor-type tyrosine-protein phosphatase C	Homo sapiens (human)	1
Receptor-type tyrosine-protein phosphatase F	Homo sapiens (human)	3.065
Tissue factor	Homo sapiens (human)	0.005
Tyrosine-protein phosphatase non-receptor type 2	Homo sapiens (human)	4.38
Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)	2.8444
Liver carboxylesterase 1	Homo sapiens (human)	0.1
Tyrosine-protein phosphatase non-receptor type 6	Homo sapiens (human)	3.065
M-phase inducer phosphatase 2	Homo sapiens (human)	0.98
Dual specificity protein phosphatase 3	Homo sapiens (human)	5.4
Transcription factor p65	Homo sapiens (human)	2.4
Tyrosine-protein phosphatase non-receptor type 11	Homo sapiens (human)	3.065
Protease	Human immunodeficiency virus 1	8

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.85)	18.7374
1990's	11 (20.37)	18.2507
2000's	19 (35.19)	29.6817
2010's	18 (33.33)	24.3611
2020's	5 (9.26)	2.80

Authors

Authors	Studies
Iwashima, A; Kokumai, M; Konoshima, T; Kozuka, M; Nishino, H; Tokuda, H	1
Hashimoto, T; Takagi, T; Tsurumi, S	1
Fairweather-Tait, SJ; Fenwick, GR; Price, KR; Southon, S; Wright, AJ	1
Addy, ME; Burka, JF; Feigenbaum, P; Garcia, ML; Giangiacomo, KM; Harris, GH; Kaczorowski, GJ; McManus, OB; Reuben, JP	1
Frøkiaer, H; Møller, P; Sørensen, H; Sørensen, S	1
Jiang, Y; Ma, XY; Qi, H; Zhong, GG	1
Frøkiaer, H; Sørensen, H; Sørensen, JC; Sørensen, S	1
Fenwick, GR; Price, KR; Rhodes, MJ; Ruiz, RG	1
Chen, LF; Chou, CH; Kim, D; Lee, JS; Lee, MR; Liou, RM; Su, CH; Waller, GR; Wu, SC; Yang, CF; Young, CC	1
Lee, JS; Lee, MR; Waller, GR; Wang, JC	1
Jurzysta, M; Lee, MK; Ling, YC; Waller, GR	1
Arao, T; Kinjo, J; Miyao, H; Nohara, T; Udayama, M	1
Hirakawa, T; Kinjo, J; Nohara, T; Shii, Y; Uyeda, M; Yokomizo, K	1
Chen, ST; Hsu, CC; Tsai, YC; Wu, CY	1
Ebizuka, Y; Hayashi, H; Hiraoka, N; Huang, P; Ikeshiro, Y; Inoue, K; Kirakosyan, A; Kushiro, T; Shibuya, M	1
Hendrich, S; Hu, J; Lee, SO; Murphy, PA	1
Akiyama, H; Goda, Y; Kinjo, J; Nohara, T; Suyama, E; Takahashi, S; Toyoda, M	1
Hayashi, H; Huang, P; Inoue, K	1
Doi, S; Suzuki, K; Uyeda, M; Yahara, S	1
Hendrich, S; Hu, J; Hyde, W; Murphy, PA; Zheng, YL	1
Hendrich, S; Hu, J; Murphy, PA; Reddy, MB	1
Chang, WW; Hsu, CC; Lin, TW; Lo, WH; Tsai, YC; Wang, PH; Wu, CY	1
Fields, PG; Sutherland, DH; Taylor, WG	1
Murakami, T; Sumida, N; Watanabe, M; Yanai, K	1
Chang, WW; Lin, TW; Tsai, YC; Wang, PH; Yu, CY	1
Gurfinkel, DM; Rao, AV; Reynolds, WF	1
Chen, HB; Hai, LQ; Liang, H; Wang, B; Wang, W; Zhao, YY	1
Gotoh, T; Hiwatashi, K; Hori, K; Shinbo, M; Takahashi, S; Yamada, S	1
Popovich, DG; Teng, SP; Zhang, W	1
Popovich, DG; Tang, FY; Yeo, MC; Zhang, W	1
Caprioli, G; Cristalli, G; Giardinà, D; Maggi, F; Molin, L; Ricciutelli, M; Sagratini, G; Traldi, P; Vittori, S; Zuo, Y	1
Popovich, DG; Zhang, W	1
Ebizuka, Y; Nishimura, K; Shibuya, M; Yasuyama, N	1
Gotoh, T; Hokari, M; Hori, K; Sugiyama, T; Takahashi, S	1
Han, MJ; Kim, DH; Lee, IA; Park, YJ; Yeo, HK	1
Chu, XW; Deng, H; Lu, XC; Luo, HJ; Mao, LM; Sun, SX; Ye, JF; Zha, LY	1
Caprioli, G; Font, G; Giardinà, D; Maggi, F; Mañes, J; Meca, G; Ricciutelli, M; Sagratini, G; Sirocchi, V; Torregiani, E; Vittori, S	1
Kano, Y; Lu, J; Sun, JH; Tan, Y; Yuan, D	1
Han, M; Heo, H; Hong, SW; Kim, DH; Kwon, YK; Yang, JH	1
Cai, J; Cao, W; Chen, J; Chu, X; Deng, H; Li, X; Liu, Z; Mao, L; Sun, S; Zha, L	1
Fernández-Blanco, C; Font, G; Ruiz, MJ; Sagratini, G; Vila-Donat, P	1
Beermann, C; Fußbroich, D; Schneider, P; Schubert, R; Zielen, S	1
Cao, W; Guo, Z; Han, B; Han, Z; Zhao, S	1
Ranjbar, B; Taghdir, M; Tavassoli, Z	1
Chou, YT; Hsieh, SL; Lee, OK; Sung, PL; Wang, PH; Wen, KC; Wu, CW	1
Hanashima, S; Malabed, R; Murata, M; Sakurai, K	1
Sallam, SM; Shawky, E	1
Chang, CM; Chen, YJ; Horng, HC; Lee, WL; Sung, PL; Wang, PH; Wen, KC	1
MacDonell, EC; Rajcan, I	1
Elwakeel, A; Kalra, RS; Kaul, SC; Omar, A; Putri, J; Wadhwa, R	1
Akasaka, T; Jiang, Z; Katakura, Y; Nakamura, Y; Sato, M; Shirouchi, B; Tanaka, Y; Tsai, WT; Yuan, X	1
Huang, R; Lin, Q; Liu, Z; Xia, X; Yang, J; Zeng, J; Zhao, N	1
Cheng, Y; Wang, Y; Wu, Y; Xiang, Z; Yu, X	1
Li, L; Li, SG; Li, W; Li, X; Li, ZS; Xiong, Y; Xiong, YY; Yang, LJ; Ye, AY; Zhang, Y	1

Trials

1 trial(s) available for soyasaponin bb and oleanolic acid

Article	Year
Soyasaponin I and sapongenol B have limited absorption by Caco-2 intestinal cells and limited bioavailability in women. The Journal of nutrition, 2004, Volume: 134, Issue:8 Topics: Administration, Oral; Adult; Biological Availability; Caco-2 Cells; Female; Humans; Intestinal Absorption; Oleanolic Acid; Saponins	2004

Other Studies

53 other study(ies) available for soyasaponin bb and oleanolic acid

Article	Year
Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys. Journal of natural products, 1992, Volume: 55, Issue:12 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Isoflavones; Lung Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate	1992
A gamma-pyronyl-triterpenoid saponin from Pisum sativum. Phytochemistry, 1992, Volume: 31, Issue:7 Topics: Carbohydrate Sequence; Fabaceae; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Saponins	1992
The effect of three types of saponin on iron and zinc absorption from a single meal in the rat. The British journal of nutrition, 1988, Volume: 59, Issue:3 Topics: Absorption; Animals; Dietary Carbohydrates; Iron; Male; Medicago sativa; Oleanolic Acid; Rats; Rats, Inbred Strains; Saponins; Zinc	1988
An activator of calcium-dependent potassium channels isolated from a medicinal herb. Biochemistry, 1993, Jun-22, Volume: 32, Issue:24 Topics: Animals; Calcium; Cattle; Charybdotoxin; In Vitro Techniques; Ion Channel Gating; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle, Smooth; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Potassium Channels; Saponins; Scorpion Venoms; Structure-Activity Relationship; Triterpenes	1993
High-performance capillary electrophoresis for characterization of hapten-protein conjugates used for production of antibodies against soyasaponin I. Journal of chromatography. A, 1994, Oct-07, Volume: 680, Issue:2 Topics: Animals; Antibody Formation; Capillary Action; Electrophoresis; Haptens; Immunization; Micelles; Nitrophenylgalactosides; Oleanolic Acid; Pisum sativum; Rabbits; Saponins; Serum Albumin, Bovine; Trypsin Inhibitor, Kunitz Soybean	1994
[Antioxidative action of soyasaponin monomers I, A1, A2, and their inhibitory effects on action potential and beating of myocardiocytes in culture]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:3 Topics: Action Potentials; Animals; Antioxidants; Calcium Channel Blockers; Cells, Cultured; Free Radicals; Myocardium; Oleanolic Acid; Rats; Rats, Wistar; Saponins; Xanthine Oxidase; Xanthines	1993
Optimization of hapten-protein conjugation by high-performance capillary electrophoresis. Journal of chromatography. A, 1995, Nov-24, Volume: 717, Issue:1-2 Topics: Electrophoresis, Capillary; Haptens; Kinetics; Nitrophenylgalactosides; Oleanolic Acid; Oxidation-Reduction; Periodic Acid; Saponins; Trypsin Inhibitor, Kunitz Soybean	1995
Effect of processing on saponin content and composition of chickpeas. Biochemical Society transactions, 1996, Volume: 24, Issue:3 Topics: Carbohydrate Sequence; Cooking; Fabaceae; Molecular Sequence Data; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Saponins; Time Factors	1996
Can soyasaponin I and mono- and bi-desmosides isolated from mungbeans serve as growth enhancers in mungbeans and lettuce? Advances in experimental medicine and biology, 1996, Volume: 405 Topics: Chromatography, Thin Layer; Fabaceae; Lactuca; Molecular Structure; Oleanolic Acid; Plant Leaves; Plant Roots; Plants, Medicinal; Saponins	1996
Structural determination of saponins from mungbean sprouts by tandem mass spectrometry. Advances in experimental medicine and biology, 1996, Volume: 405 Topics: Carbohydrate Sequence; Fabaceae; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Saponins; Spectrometry, Mass, Fast Atom Bombardment	1996
Saponins from alfalfa, clover, and mungbeans analyzed by electrospray ionization-mass spectrometry as compared with positive and negative FAB-mass spectrometry. Advances in experimental medicine and biology, 1996, Volume: 405 Topics: Fabaceae; Mass Spectrometry; Medicago sativa; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Saponins; Seeds; Spectrometry, Mass, Fast Atom Bombardment	1996
Kaikasaponin III and soyasaponin I, major triterpene saponins of Abrus cantoniensis, act on GOT and GPT: influence on transaminase elevation of rat liver cells concomitantly exposed to CCl4 for one hour. Planta medica, 1998, Volume: 64, Issue:1 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbohydrate Sequence; Carbon Tetrachloride; Liver; Male; Medicine, Chinese Traditional; Molecular Sequence Data; Oleanolic Acid; Plants, Medicinal; Rats; Rats, Wistar; Saponins	1998
Anti-herpes virus activity of fabaceous triterpenoidal saponins'). Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:7 Topics: Animals; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Herpesvirus 1, Human; Microbial Sensitivity Tests; Oleanolic Acid; Rosales; Saponins; Structure-Activity Relationship; Triterpenes; Vero Cells	2000
Soyasaponin I, a potent and specific sialyltransferase inhibitor. Biochemical and biophysical research communications, 2001, Jun-08, Volume: 284, Issue:2 Topics: Animals; beta-Galactoside alpha-2,3-Sialyltransferase; Binding, Competitive; Brain; COS Cells; Cytidine Monophosphate N-Acetylneuraminic Acid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Fucosyltransferases; Galactosyltransferases; Mice; Oleanolic Acid; Saponins; Sialyltransferases; Substrate Specificity	2001
Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice. Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:8 Topics: Amino Acid Sequence; Blotting, Northern; Blotting, Southern; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Glycyrrhiza; Glycyrrhizic Acid; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; RNA, Messenger; Saccharomyces cerevisiae; Saponins	2001
Quantification of the group B soyasaponins by high-performance liquid chromatography. Journal of agricultural and food chemistry, 2002, Apr-24, Volume: 50, Issue:9 Topics: Chromatography, High Pressure Liquid; Drug Stability; Food Analysis; Food Handling; Glycine max; Hot Temperature; Isoflavones; Oleanolic Acid; Saponins; Soybean Proteins	2002
[Comparison of soyasaponin and isoflavone contents between genetically modified (GM) and non-GM soybeans]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2002, Volume: 43, Issue:6 Topics: Food, Genetically Modified; Glycine max; Isoflavones; Oleanolic Acid; Saponins	2002
Up-regulation of soyasaponin biosynthesis by methyl jasmonate in cultured cells of Glycyrrhiza glabra. Plant & cell physiology, 2003, Volume: 44, Issue:4 Topics: Acetates; Cells, Cultured; Cyclopentanes; Farnesyl-Diphosphate Farnesyltransferase; Glucuronosyltransferase; Glycyrrhiza; Intramolecular Transferases; Oleanolic Acid; Oxylipins; RNA, Messenger; Saponins	2003
2070-DTI, a topoisomerase inhibitor produced by Streptomyces sp. strain No. 2070. Journal of enzyme inhibition and medicinal chemistry, 2003, Volume: 18, Issue:6 Topics: Animals; Camptothecin; Carbohydrate Sequence; Cattle; Cell Cycle; Chlorocebus aethiops; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; Mice; Molecular Sequence Data; NIH 3T3 Cells; Oleanolic Acid; Saponins; Streptomyces; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Vero Cells	2003
Human fecal metabolism of soyasaponin I. Journal of agricultural and food chemistry, 2004, May-05, Volume: 52, Issue:9 Topics: Adolescent; Adult; Anaerobiosis; Feces; Female; Humans; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Middle Aged; Oleanolic Acid; Saponins; Spectrometry, Mass, Electrospray Ionization	2004
Soyasaponin-I-modified invasive behavior of cancer by changing cell surface sialic acids. Gynecologic oncology, 2005, Volume: 96, Issue:2 Topics: beta-Galactoside alpha-2,3-Sialyltransferase; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Matrix; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Oleanolic Acid; Saponins; Sialic Acids; Sialyltransferases	2005
Insecticidal components from field pea extracts: soyasaponins and lysolecithins. Journal of agricultural and food chemistry, 2004, Dec-15, Volume: 52, Issue:25 Topics: Animals; Glycine max; Insecticides; Lysophosphatidylcholines; Oleanolic Acid; Pisum sativum; Plant Extracts; Saponins; Weevils	2004
Cloning and characterization of saponin hydrolases from Aspergillus oryzae and Eupenicillium brefeldianum. Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:11 Topics: Amino Acid Sequence; Aspergillus oryzae; Cloning, Molecular; Glycoproteins; Hydrolases; Molecular Weight; Oleanolic Acid; Saponins; Sequence Homology; Substrate Specificity; Trioses	2005
Soyasaponin I decreases the expression of alpha2,3-linked sialic acid on the cell surface and suppresses the metastatic potential of B16F10 melanoma cells. Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2 Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Movement; Extracellular Matrix; Flow Cytometry; Glycine max; Glycosylation; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; N-Acetylneuraminic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; NIH 3T3 Cells; Oleanolic Acid; Saponins; Sialic Acids	2006
The isolation of soyasaponins by fractional precipitation, solid phase extraction, and low pressure liquid chromatography. International journal of food sciences and nutrition, 2005, Volume: 56, Issue:7 Topics: Chromatography, Liquid; Fractional Precipitation; Glycine max; Oleanolic Acid; Saponins	2005
[Saponins from roots of Hedysarum multijugum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:4 Topics: Fabaceae; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Saponins	2007
Isolation of human renin inhibitor from soybean: soyasaponin I is the novel human renin inhibitor in soybean. Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:12 Topics: Amino Acid Sequence; Animals; Blood Pressure; Enzyme Inhibitors; Glycine max; Humans; Hypertension; Inhibitory Concentration 50; Kinetics; Male; Oleanolic Acid; Rats; Renin; Saponins	2008
Generation of group B soyasaponins I and III by hydrolysis. Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9 Topics: Chromatography, High Pressure Liquid; Glycine max; Hydrogen-Ion Concentration; Hydrolysis; Isoflavones; Mass Spectrometry; Methanol; Oleanolic Acid; Saponins; Soy Foods; Spectrometry, Mass, Electrospray Ionization	2009
Bioactive responses of Hep-G2 cells to soyasaponin extracts differs with respect to extraction conditions. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:9 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Hepatocytes; Humans; Liver Neoplasms; Oleanolic Acid; Plant Extracts; Saponins; Soybean Proteins; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles	2009
Quantification of soyasaponins I and betag in Italian lentil seeds by solid-phase extraction (SPE) and high-performance liquid chromatography-mass spectrometry (HPLC-MS). Journal of agricultural and food chemistry, 2009, Dec-09, Volume: 57, Issue:23 Topics: Chromatography, High Pressure Liquid; Italy; Lens Plant; Mass Spectrometry; Oleanolic Acid; Plant Extracts; Saponins; Seeds; Solid Phase Extraction	2009
Group B oleanane triterpenoid extract containing soyasaponins I and III from soy flour induces apoptosis in Hep-G2 cells. Journal of agricultural and food chemistry, 2010, May-12, Volume: 58, Issue:9 Topics: Cell Line, Tumor; Chromatography, High Pressure Liquid; Flour; Flow Cytometry; Glycine max; Humans; In Situ Nick-End Labeling; Oleanolic Acid; Plant Extracts; Saponins; Triterpenes	2010
Identification and characterization of glycosyltransferases involved in the biosynthesis of soyasaponin I in Glycine max. FEBS letters, 2010, Jun-03, Volume: 584, Issue:11 Topics: Glycine max; Glycosyltransferases; Oleanolic Acid; Saponins; Triterpenes	2010
Inhibition of human renin activity by saponins. Biomedical research (Tokyo, Japan), 2010, Volume: 31, Issue:2 Topics: Fruit; Glycine max; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Oleanolic Acid; Renin; Saponins	2010
Soyasaponin I attenuates TNBS-Induced colitis in mice by inhibiting NF-κB pathway. Journal of agricultural and food chemistry, 2010, Oct-27, Volume: 58, Issue:20 Topics: Animals; Colitis; Cyclooxygenase 2; Glycine max; Humans; Interleukin-1; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; NF-kappa B; Oleanolic Acid; Plant Extracts; Saponins; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2010
Anti-inflammatory effect of soyasaponins through suppressing nitric oxide production in LPS-stimulated RAW 264.7 cells by attenuation of NF-κB-mediated nitric oxide synthase expression. Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8 Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Saponins; Tumor Necrosis Factor-alpha	2011
Determination of soyasaponins I and βg in raw and cooked legumes by solid phase extraction (SPE) coupled to liquid chromatography (LC)-mass spectrometry (MS) and assessment of their bioaccessibility by an in vitro digestion model. Journal of agricultural and food chemistry, 2013, Feb-27, Volume: 61, Issue:8 Topics: Biological Availability; Chromatography, High Pressure Liquid; Digestion; Fabaceae; Humans; Mass Spectrometry; Oleanolic Acid; Saponins; Solid Phase Extraction	2013
New triterpenoid saponins from the flowers of Pueraria thomsonii. Journal of Asian natural products research, 2013, Volume: 15, Issue:10 Topics: Drugs, Chinese Herbal; Flowers; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pueraria; Saponins	2013
Soyasaponin I improved neuroprotection and regeneration in memory deficient model rats. PloS one, 2013, Volume: 8, Issue:12 Topics: Animals; Behavior, Animal; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Hippocampus; Ibotenic Acid; Male; Memory; Memory Disorders; Microglia; Nerve Regeneration; Neural Stem Cells; Neurons; Neuroprotective Agents; Oleanolic Acid; Pregnancy; Rats; Rats, Sprague-Dawley; Saponins	2013
Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway. PloS one, 2014, Volume: 9, Issue:9 Topics: Animals; Cell Line; Chromones; Cyclooxygenase 2; Dinoprostone; Glycine max; I-kappa B Kinase; Inflammation; Lipopolysaccharides; Macrophages; Malondialdehyde; Mice; Morpholines; Nitriles; Oleanolic Acid; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Saponins; Signal Transduction; Sulfones; Superoxide Dismutase; Transcription Factor RelA	2014
Effects of soyasaponin I and soyasaponins-rich extract on the alternariol-induced cytotoxicity on Caco-2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 77 Topics: Alternaria; Antioxidants; Caco-2 Cells; Cell Proliferation; Cell Survival; Cytoprotection; DNA Damage; Drug Synergism; Humans; Lactones; Lens Plant; Mycotoxins; Oleanolic Acid; Plant Extracts; Saponins	2015
Impact of soyasaponin I on TLR2 and TLR4 induced inflammation in the MUTZ-3-cell model. Food & function, 2015, Volume: 6, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; B7-2 Antigen; Cell Line, Tumor; Cell Proliferation; Cell Shape; Chemokines; Cytokines; Endotoxins; Humans; Immunologic Factors; Leukemia, Myeloid, Acute; Monocytes; Neoplasm Proteins; Oleanolic Acid; Osmolar Concentration; Saponins; Toll-Like Receptor 2; Toll-Like Receptor 4	2015
Protection against 1-methyl-4-phenyl pyridinium-induced neurotoxicity in human neuroblastoma SH-SY5Y cells by Soyasaponin I by the activation of the phosphoinositide 3-kinase/AKT/GSK3β pathway. Neuroreport, 2016, 07-06, Volume: 27, Issue:10 Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Humans; Neuroprotective Agents; Oleanolic Acid; Parkinson Disease; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Saponins; Signal Transduction	2016
Renin inhibition by soyasaponin I: a potent native anti-hypertensive compound. Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:1 Topics: Antihypertensive Agents; Catalytic Domain; Humans; Hypertension; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Oleanolic Acid; Protein Binding; Renin; Renin-Angiotensin System; Saponins; Thermodynamics	2018
α2,3-sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells. Oncotarget, 2017, Apr-25, Volume: 8, Issue:17 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; beta-Galactoside alpha-2,3-Sialyltransferase; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Drug Synergism; ErbB Receptors; Female; Humans; Immunohistochemistry; Immunoprecipitation; Kaplan-Meier Estimate; Mice; Mice, Inbred C57BL; Microarray Analysis; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Oleanolic Acid; Ovarian Neoplasms; Ovary; Peritoneal Neoplasms; Peritoneum; Prognosis; Protein Kinase Inhibitors; Saponins; Sialyltransferases; Signal Transduction; Survival Rate	2017
Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins. Biochimica et biophysica acta. Biomembranes, 2017, Volume: 1859, Issue:12 Topics: Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Biological Transport; Cholestenones; Cholesterol; Digitonin; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Fluoresceins; Glycyrrhizic Acid; Hemolysis; Humans; Membrane Lipids; Oleanolic Acid; Ornithogalum; Phosphatidylcholines; Saponins; Unilamellar Liposomes	2017
Simultaneous Determination of Soyasaponins and Isoflavones in Soy (Glycine max L.) Products by HPTLC-densitometry-Multiple Detection. Journal of chromatographic science, 2017, Nov-01, Volume: 55, Issue:10 Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Glycine max; Isoflavones; Limit of Detection; Linear Models; Oleanolic Acid; Reproducibility of Results; Saponins	2017
The role of α2,3-linked sialylation on clear cell type epithelial ovarian cancer. Taiwanese journal of obstetrics & gynecology, 2018, Volume: 57, Issue:2 Topics: Adenocarcinoma, Clear Cell; Animals; beta-Galactoside alpha-2,3-Sialyltransferase; Cadherins; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cystadenocarcinoma, Serous; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms, Glandular and Epithelial; Oleanolic Acid; Ovarian Neoplasms; Saponins; Sialyltransferases	2018
Identification of quantitative trait loci associated with soyasaponin I concentration in soybean seed. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2018, Volume: 131, Issue:10 Topics: Chromosome Mapping; Glycine max; Oleanolic Acid; Ontario; Phenotype; Quantitative Trait Loci; Saponins; Seeds	2018
Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells. Scientific reports, 2020, 04-14, Volume: 10, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Oleanolic Acid; RNA-Binding Proteins; Saponins; Signal Transduction; Transcriptional Activation; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2020
Soyasaponin ameliorates obesity and reduces hepatic triacylglycerol accumulation by suppressing lipogenesis in high-fat diet-fed mice. Journal of food science, 2021, Volume: 86, Issue:5 Topics: 3T3-L1 Cells; Adipogenesis; Adipose Tissue; Animals; Anti-Obesity Agents; Cell Differentiation; Diet, High-Fat; Lipid Metabolism; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Oleanolic Acid; Saponins; Triglycerides	2021
Anti-Colon Cancer Activity of Dietary Phytochemical Soyasaponin I and the Induction of Metabolic Shifts in HCT116. Molecules (Basel, Switzerland), 2022, Jul-08, Volume: 27, Issue:14 Topics: Colonic Neoplasms; Humans; Molecular Docking Simulation; Oleanolic Acid; Phytochemicals; Saponins	2022
Metabolic profiling of soyasaponin Bb in rat plasma, urine, bile, and feces after intragastric administration. Biomedical chromatography : BMC, 2022, Volume: 36, Issue:11 Topics: Administration, Oral; Animals; Antioxidants; Bile; Chromatography, High Pressure Liquid; Feces; Oleanolic Acid; Rats; Saponins	2022
Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system. Clinical and experimental hypertension (New York, N.Y. : 1993), 2023, Dec-31, Volume: 45, Issue:1 Topics: Animals; Intracranial Hemorrhage, Hypertensive; Oleanolic Acid; Rats; Renin-Angiotensin System; Saponins	2023