soyasapogenol a has been researched along with oleanolic acid in 20 studies
| Studies (soyasapogenol a) | Trials (soyasapogenol a) | Recent Studies (post-2010) (soyasapogenol a) | Studies (oleanolic acid) | Trials (oleanolic acid) | Recent Studies (post-2010) (oleanolic acid) |
|---|---|---|---|---|---|
| 22 | 0 | 11 | 4,169 | 31 | 2,404 |
| Protein | Taxonomy | soyasapogenol a (IC50) | oleanolic acid (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 2.045 | |
| Phospholipase A2 | Homo sapiens (human) | 3 | |
| DNA polymerase beta | Homo sapiens (human) | 6.8667 | |
| DNA polymerase beta | Rattus norvegicus (Norway rat) | 5.6 | |
| Receptor-type tyrosine-protein phosphatase C | Homo sapiens (human) | 1 | |
| Receptor-type tyrosine-protein phosphatase F | Homo sapiens (human) | 3.065 | |
| Tissue factor | Homo sapiens (human) | 0.005 | |
| Tyrosine-protein phosphatase non-receptor type 2 | Homo sapiens (human) | 4.38 | |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 2.8444 | |
| Liver carboxylesterase 1 | Homo sapiens (human) | 0.1 | |
| Tyrosine-protein phosphatase non-receptor type 6 | Homo sapiens (human) | 3.065 | |
| M-phase inducer phosphatase 2 | Homo sapiens (human) | 0.98 | |
| Dual specificity protein phosphatase 3 | Homo sapiens (human) | 5.4 | |
| Transcription factor p65 | Homo sapiens (human) | 2.4 | |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | 3.065 | |
| Protease | Human immunodeficiency virus 1 | 8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuzuhara, H; Minowa, N; Nishiyama, S; Omoto, S; Sasaki, K | 2 |
| Kurosawa, Y; Shiraiwa, M; Takahara, H | 1 |
| Badger, TM; Berhow, MA; Rowlands, JC | 1 |
| Gu, L; Gu, W; Prior, RL; Tao, G | 1 |
| Heinrich, PC; Klein, C; Manns, MP; Streetz, KL; Trautwein, C; Wüstefeld, T | 1 |
| Bewley, JD; Di Berardo, C; Jackson, CJ; Jenkinson, J; Poysa, V; Rupasinghe, HP | 1 |
| Gurfinkel, DM; Rao, AV | 1 |
| Gurfinkel, DM; Rao, AV; Reynolds, WF | 1 |
| Popovich, DG; Zhang, W | 1 |
| Chu, XW; Deng, H; Lu, XC; Luo, HJ; Mao, LM; Sun, SX; Ye, JF; Zha, LY | 1 |
| Chung, IM; Kim, EH; Kim, HS; Kim, SL; Ro, HM | 1 |
| Ishimoto, M; Kato, S; Kikuchi, A; Sasama, H; Sayama, T; Takada, Y; Tsukamoto, C | 1 |
| Kamo, S; Sato, T; Suzuki, S | 1 |
| Chung, IM; Kim, SH; Yu, BR | 1 |
| Anai, T; Ishimoto, M; Kaga, A; Mukaiyama, K; Ohyama, K; Saito, K; Sawai, S; Sayama, T; Takada, Y; Takagi, K; Tsukamoto, C; Yano, R | 1 |
| Androutsopoulos, VP; Chung, G; Le, B; Shin, TS; Tsatsakis, AM; Tsukamoto, C; Yang, SH | 1 |
| Dronamraju, SVL; Rajarathinam, G | 1 |
| Elwakeel, A; Kalra, RS; Kaul, SC; Omar, A; Putri, J; Wadhwa, R | 1 |
| Pan, C; Yan, Y; Zhao, D | 1 |
20 other study(ies) available for soyasapogenol a and oleanolic acid
| Article | Year |
|---|---|
Derivatization of soyasapogenol A and their hepatoprotective activities.
Topics: Cells, Cultured; Glycine max; Humans; Liver; Models, Chemical; Models, Molecular; Oleanolic Acid; Plant Extracts; Structure-Activity Relationship | 1998 |
Protective effects of soyasapogenol A on liver injury mediated by immune response in a concanavalin A-induced hepatitis model.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Concanavalin A; Cytokines; Hepatitis, Animal; Liver; Liver Function Tests; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid | 2000 |
UDP-glucuronic acid:soyasapogenol glucuronosyltransferase involved in saponin biosynthesis in germinating soybean seeds.
Topics: Carbon Radioisotopes; Cations; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Activation; Germination; Glucuronosyltransferase; Glycine max; Hydrogen-Ion Concentration; Kinetics; Magnesium; Microsomes; Oleanolic Acid; Saponins; Seeds; Solubility; Substrate Specificity; Temperature; Uridine Diphosphate Glucuronic Acid | 2002 |
Estrogenic and antiproliferative properties of soy sapogenols in human breast cancer cells in vitro.
Topics: Blotting, Northern; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Estrogens, Non-Steroidal; Female; Fulvestrant; Gene Expression; Glycine max; Humans; Isoflavones; Oleanolic Acid; Phytoestrogens; Plant Extracts; Plant Preparations; Receptors, Estrogen; RNA, Messenger; Saponins; Tumor Cells, Cultured | 2002 |
Determination of soyasaponins in soy with LC-MS following structural unification by partial alkaline degradation.
Topics: Chromatography, High Pressure Liquid; Glycine max; Hydrogen-Ion Concentration; Oleanolic Acid; Saponins; Spectrometry, Mass, Electrospray Ionization | 2002 |
ME3738 protects from concanavalin A-induced liver failure via an IL-6-dependent mechanism.
Topics: Acute-Phase Reaction; Animals; Concanavalin A; DNA-Binding Proteins; Gene Expression; Immunosuppressive Agents; Interleukin-6; Liver Failure; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; NF-kappa B; Oleanolic Acid; STAT3 Transcription Factor; Trans-Activators; Tumor Necrosis Factor-alpha | 2003 |
Soyasapogenol A and B distribution in soybean (Glycine max L. Merr.) in relation to seed physiology, genetic variability, and growing location.
Topics: Germination; Glycine max; Isoflavones; Oleanolic Acid; Saponins; Seedlings; Seeds; Water | 2003 |
Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity.
Topics: Acetylation; Anticarcinogenic Agents; Cell Division; Colonic Neoplasms; Fabaceae; Fermentation; Humans; Molecular Structure; Oleanolic Acid; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
The isolation of soyasaponins by fractional precipitation, solid phase extraction, and low pressure liquid chromatography.
Topics: Chromatography, Liquid; Fractional Precipitation; Glycine max; Oleanolic Acid; Saponins | 2005 |
Effect of soyasapogenol A and soyasapogenol B concentrated extracts on HEP-G2 cell proliferation and apoptosis.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Mass Spectrometry; Oleanolic Acid; Plant Extracts; Saponins | 2008 |
Anti-inflammatory effect of soyasaponins through suppressing nitric oxide production in LPS-stimulated RAW 264.7 cells by attenuation of NF-κB-mediated nitric oxide synthase expression.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Saponins; Tumor Necrosis Factor-alpha | 2011 |
Analysis of isoflavone, phenolic, soyasapogenol, and tocopherol compounds in soybean [ Glycine max (L.) Merrill] germplasms of different seed weights and origins.
Topics: Antioxidants; China; Glycine max; Isoflavones; Oleanolic Acid; Phenols; Republic of Korea; Saponins; Seeds; Tocopherols; United States | 2012 |
Genetic and chemical analysis of a key biosynthetic step for soyasapogenol A, an aglycone of group A saponins that influence soymilk flavor.
Topics: Alleles; Chromosome Mapping; Chromosomes, Plant; Gene Deletion; Genes, Recessive; Genetic Loci; Glycine max; Microsatellite Repeats; Oleanolic Acid; Saponins; Soy Milk; Taste | 2013 |
Comparison of bioavailability (I) between soyasaponins and soyasapogenols, and (II) between group A and B soyasaponins.
Topics: Animals; Caco-2 Cells; Humans; Intestinal Absorption; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins | 2014 |
Changes in the contents and profiles of selected phenolics, soyasapogenols, tocopherols, and amino acids during soybean-rice mixture cooking: Electric rice cooker vs electric pressure rice cooker.
Topics: Amino Acids; Cooking; Glycine max; Isoflavones; Oleanolic Acid; Oryza; Phenols; Tocopherols | 2015 |
Metabolic switching of astringent and beneficial triterpenoid saponins in soybean is achieved by a loss-of-function mutation in cytochrome P450 72A69.
Topics: Base Sequence; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Variation; Glycine max; Mixed Function Oxygenases; Molecular Structure; Mutation; Oleanolic Acid; Phylogeny; Plant Proteins; Saponins; Triterpenes | 2017 |
Anti-inflammatory effects of soyasapogenol I-αa via downregulation of the MAPK signaling pathway in LPS-induced RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Down-Regulation; Glycine max; Interleukin-1beta; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Plant Extracts; RAW 264.7 Cells; Tumor Necrosis Factor-alpha | 2018 |
Anti-inflammatory activity of dimethyl octenol and oleanene tetrol isolated from Trianthema decandra L.
Topics: Aizoaceae; Animals; Anti-Inflammatory Agents; Arthritis; Cyclooxygenase 2; Disease Models, Animal; Inflammation; Macrophages; Male; Mice; Molecular Docking Simulation; Nitric Oxide; Octanols; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Leaves; RAW 264.7 Cells; Tumor Necrosis Factor-alpha | 2018 |
Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Oleanolic Acid; RNA-Binding Proteins; Saponins; Signal Transduction; Transcriptional Activation; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2020 |
The Fate and Intermediary Metabolism of Soyasapogenol in the Rat.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Liver; Oleanolic Acid; Rats; Tandem Mass Spectrometry | 2022 |