sotalol has been researched along with theophylline in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (37.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Roch, P; Salamin, A | 1 |
| Holzmann, S; Kukovetz, WR; Pöch, G; Rinner, I; Wurm, A | 1 |
| Hodgins, DS; Kuo, JF; Kuo, WN | 1 |
| Andersson, R; Lundholm, L; Mohme-Lundholm, E; Nilsson, K | 1 |
| Gilman, AG | 1 |
| Greengard, P; Kalix, P; McAfee, DA; Schorderet, M | 1 |
| Diekema, A; Veninga, T | 1 |
| St-Louis, J | 1 |
| Benjamin, AR; Stephens, RH; Walters, DV | 1 |
1 review(s) available for sotalol and theophylline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
23 other study(ies) available for sotalol and theophylline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effect of beta-adrenergic drugs on adenosine 3', 5'-monophosphate in rabbit vagus nerve.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Brain; Cattle; Cyclic AMP; Epinephrine; Ganglia, Autonomic; Guinea Pigs; In Vitro Techniques; Isoproterenol; Organ Specificity; Propranolol; Rabbits; Sotalol; Theophylline; Vagus Nerve | 1977 |
Role of cyclic nucleotides in adenosine-mediated regulation of coronary flow.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cattle; Coronary Circulation; Coronary Vessels; Digitonin; Drug Interactions; In Vitro Techniques; Isoproterenol; Nucleotides, Cyclic; Papaverine; Phosphatidylserines; Sodium Fluoride; Sotalol; Theophylline; Time Factors | 1978 |
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium | 1974 |
Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.
Topics: Adenosine Triphosphate; Animals; Barium; Calcium; Calcium Isotopes; Carbachol; Colon; Corticosterone; Cyclic AMP; Dibenzylchlorethamine; Glucosyltransferases; Hexosephosphates; Isoproterenol; Lactates; Muscle Contraction; Muscle, Smooth; Phenylephrine; Phosphocreatine; Potassium; Rabbits; Receptors, Adrenergic; Sotalol; Theophylline | 1972 |
Regulation of cyclic AMP metabolism in cultured cells of the nervous system.
Topics: Adenosine; Aminobutyrates; Animals; Brain; Carbachol; Catecholamines; Cell Division; Cells, Cultured; Cyclic AMP; Dopamine; Fetus; Histamine; Isoproterenol; Mice; Neuroblastoma; Neuroglia; Neurons; Phentolamine; Prostaglandins; Rats; Serotonin; Sotalol; Theophylline; Time Factors | 1972 |
Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.
Topics: Adenosine; Animals; Atropine; Benzyl Compounds; Bethanechol Compounds; Calcium; Carbachol; Cyclic AMP; Electric Stimulation; Ethers; Ganglia, Spinal; Hexamethonium Compounds; Imidazoles; In Vitro Techniques; Moxisylyte; Parasympatholytics; Phenoxybenzamine; Phentolamine; Phosphodiesterase Inhibitors; Rabbits; Sotalol; Sympatholytics; Synapses; Theophylline; Time Factors | 1974 |
Elevation of body temperature in rabbits by x-irradiation of the trunk.
Topics: Adrenal Glands; Adrenalectomy; Animals; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Radiation; Ergotamine; Hypothalamus; Leukocytes; Phentolamine; Propranolol; Rabbits; Radiation Effects; Sotalol; Theophylline; Time Factors | 1974 |
Pharmacological studies on the action of relaxin upon KCl-contracted rat uterus.
Topics: Animals; Drug Interactions; Female; Histamine; In Vitro Techniques; Isoproterenol; Muscle, Smooth; Potassium Chloride; Rats; Relaxin; Sotalol; Theophylline; Uterine Contraction | 1982 |
The regulation of lung liquid absorption by endogenous cAMP in postnatal sheep lungs perfused in situ.
Topics: Absorption; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Bucladesine; Cyclic AMP; Lung; Osmotic Pressure; Perfusion; Phosphodiesterase Inhibitors; Purinergic Antagonists; Pyrrolidinones; Rolipram; Sheep; Sotalol; Theophylline | 1998 |