Page last updated: 2024-08-16

sotalol and sematilide

sotalol has been researched along with sematilide in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's10 (62.50)18.2507
2000's3 (18.75)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Argentieri, TM; Davey, DD; DeVita, RJ; Gomez, RP; Jain, VK; Lumma, WC; Marisca, AJ; Morgan, TK; Reiser, HJ; Wohl, RA1
Kaiho, T; Kamiya, J; Katakami, T; Kawauchi, N; Miyamoto, M; Mori, H; Nobori, T; San-nohe, K; Yokoyama, T1
Davey, DD; Gomez, RP; Lind, JM; Lis, R; Marisca, AJ; Morgan, TK; Phillips, GB; Sullivan, ME1
Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Brockmöller, J; Dücker, C; Jensen, O1
Honerjäger, P; Schmidt, G1
Blackburn, KJ; Burges, RA; Gwilt, M; Higgins, AJ; Milne, AA; Solca, AM1
Krafte, DS; Volberg, WA1
Cui, G; Sager, P; Sen, L; Singh, BN; Uppal, P1
Imaizumi, Y; Ishii, Y; Kurihara, A; Muraki, K; Watanabe, M1
Baskin, EP; Guinosso, PJ; Hamill, T; Lynch, JJ; Nutt, EM; Salata, JJ; Woods, CM1
Lee, EW; Lee, KS; Tsai, TD1
Al-Khalidi, H; Brooks, RR; Drexler, AP; Kostreva, DR; Maynard, AE1

Reviews

1 review(s) available for sotalol and sematilide

ArticleYear
[New anti-arrhythmia agents].
    Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Phenethylamines; Procainamide; Propanolamines; Sotalol; Sulfonamides; Survival Rate; Tachycardia

1992

Trials

1 trial(s) available for sotalol and sematilide

ArticleYear
Effects of amiodarone, sematilide, and sotalol on QT dispersion.
    The American journal of cardiology, 1994, Nov-01, Volume: 74, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Follow-Up Studies; Heart Conduction System; Humans; Male; Middle Aged; Procainamide; Retrospective Studies; Sotalol; Tachycardia, Ventricular; Time Factors

1994

Other Studies

14 other study(ies) available for sotalol and sematilide

ArticleYear
Rational design of 4-[(methylsulfonyl)amino]benzamides as class III antiarrhythmic agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzamides; Chemical Phenomena; Chemistry; Dogs; Electric Conductivity; Kinetics; Purkinje Fibers; Structure-Activity Relationship; Sulfonamides

1987
Synthesis and pharmacological studies of N-substituted 6-[(2-aminoethyl)amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinediones, novel class III antiarrhythmic agents.
    Journal of medicinal chemistry, 1992, Sep-04, Volume: 35, Issue:18

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Female; In Vitro Techniques; Male; Pyrimidinones; Structure-Activity Relationship

1992
Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:10

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Chemical Phenomena; Chemistry, Physical; Dogs; Drug Design; Epinephrine; Heart Rate; In Vitro Techniques; Propanolamines; Purkinje Fibers; Receptors, Adrenergic, beta

1990
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents.
    Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship

1993
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Identification of Novel High-Affinity Substrates of OCT1 Using Machine Learning-Guided Virtual Screening and Experimental Validation.
    Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5

    Topics: Databases, Chemical; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Machine Learning; Octamer Transcription Factor-1; Organic Chemicals

2021
Electropharmacology of dofetilide, a new class III agent, in anaesthetised dogs.
    European journal of pharmacology, 1992, May-14, Volume: 215, Issue:2-3

    Topics: Action Potentials; Anesthesia; Animals; Anti-Arrhythmia Agents; Dogs; Heart; Heart Ventricles; Hemodynamics; Phenethylamines; Potassium Channels; Procainamide; Refractory Period, Electrophysiological; Sotalol; Sulfonamides; Ventricular Fibrillation

1992
Voltage dependence of cardiac delayed rectifier block by methanesulfonamide class III antiarrhythmic agents.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Phenethylamines; Piperidines; Procainamide; Pyridines; Sotalol; Stereoisomerism; Sulfonamides; Ventricular Function

1994
Effects of sematilide, a novel class III antiarrhythmic agent, on action potential in guinea pig atrium.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electric Stimulation; Electrophysiology; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Myocardium; Procainamide; Refractory Period, Electrophysiological; Sotalol

1995
Comparison of binding to rapidly activating delayed rectifier K+ channel, IKr, and effects on myocardial refractoriness for class III antiarrhythmic agents.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Binding, Competitive; Chromans; Electrophysiology; Guinea Pigs; Heart Ventricles; Papillary Muscles; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels; Procainamide; Pyridines; Sotalol; Structure-Activity Relationship; Sulfonamides; Tritium

1995
Membrane activity of class III antiarrhythmic compounds; a comparison between ibutilide, d-sotalol, E-4031, sematilide and dofetilide.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Phenethylamines; Piperidines; Potassium Channels; Procainamide; Pyridines; Sotalol; Sulfonamides

1993
Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 223, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Male; Methoxamine; Phenethylamines; Piperazines; Procainamide; Quaternary Ammonium Compounds; Rabbits; Sotalol; Sulfonamides

2000