sotalol has been researched along with quinidine in 104 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (14.42) | 18.7374 |
| 1990's | 39 (37.50) | 18.2507 |
| 2000's | 28 (26.92) | 29.6817 |
| 2010's | 19 (18.27) | 24.3611 |
| 2020's | 3 (2.88) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Klein, G; Schinz, A; Schnelle, K | 1 |
| Almgren, O; Carlsson, L; Duker, G | 1 |
| Grundke, M; Ravens, U; Wettwer, E | 1 |
| Deiwick, M; Konertz, W; Scheld, HH; Weyand, M | 1 |
| Kanno, M; Komeichi, K; Nakaya, H; Shimizu, M; Tohse, N; Zhu, MY | 1 |
| Crijns, HJ; Gosselink, AM; Hillege, H; Lie, KI; Van Gelder, IC; Van Gilst, WH | 1 |
| Cheymol, G; Chézalviel, F; Davy, JM; Engel, F; Ertzbischoff, O; Lainée, P; Motté, G; Penin, E; Poirier, JM; Weissenburger, J | 1 |
| Feld, GK | 1 |
| Edvardsson, N; Juul-Möller, S; Rehnqvist-Ahlberg, N | 1 |
| Hanyok, JJ; MacNeil, DJ | 1 |
| Bauernfeind, RA; Welch, WJ | 1 |
| Anderson, JL | 1 |
| Roden, DM; Woosley, RL | 1 |
| Huang, SK; Marcus, FI | 1 |
| Constantin, L; Hopson, R; Kienzle, MG; Martins, JB; McCue, ML; Wendt, DJ | 1 |
| Bolli, R; Hill, R; Hohmann, T; Mahmarian, JJ; Pratt, CM; Roberts, R; Thornton, BC; Verani, MS; Young, JB | 1 |
| Allessie, MA; Bonke, FI; Lammers, WJ; Rensma, PL; Schalij, MJ | 1 |
| Gautam, CS; Lal, R; Pandhi, P; Sharma, PL | 1 |
| Feld, GK; Singh, BN; Venkatesh, N | 1 |
| Lawson, JW | 1 |
| Lavender, MK; Parkes, MW | 1 |
| Gettes, LS | 1 |
| Fitzgerald, JD; Wale, J | 1 |
| Lawson, JW; Wojciechowski, NJ | 1 |
| Laakso, M; Pentikäinen, PJ; Rehnberg, S | 1 |
| Baedeker, F; Hohnloser, SH; van de Loo, A | 1 |
| Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L | 1 |
| Campbell, TJ; Wyse, KR; Ye, V | 1 |
| Berman, ND; Dorian, P | 1 |
| Biblo, LA; Carlson, MD; Waldo, AL | 1 |
| Betz, P; Kalusche, D; Roskamm, H; Stockinger, J | 1 |
| Faber, TS; Hohnloser, S; Just, H; Van de Loo, A; Zehender, M | 1 |
| Lüderitz, B; Manz, M | 1 |
| Fromm, BS; Lehmann, MH; Makkar, RR; Meissner, MD; Steinman, RT | 1 |
| Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R | 1 |
| Ishii, K; Taira, N; Yamagishi, T | 1 |
| Berman, N; Dorian, P; Hardy, J; Mitchell, J; Newman, D | 1 |
| Roden, DM | 1 |
| Gautam, CS; Pandhi, P; Sharma, PL | 1 |
| Behboodikhah, M; Sager, PT | 1 |
| Bursill, JA; Campbell, TJ; Wyse, KR | 1 |
| DiMarco, JP; Jung, F | 1 |
| Dorian, P; Ham, M; Lee, SD; Newman, D | 1 |
| Behrens, S; Franz, MR; Hohnloser, SH; Woosley, RL; Zabel, M | 1 |
| Cheymol, G; Chézalviel-Guilbert, F; Davy, JM; Deplanne, V; Poirier, JM; Weissenburger, J; Xia, YZ | 1 |
| de Paola, AA; Veloso, HH | 2 |
| Guo, DL; Hu, CJ; Zeng, FD | 1 |
| Allessie, MA; Dorland, R; Wijffels, MC | 1 |
| Koch, HP; Lüderitz, B; Meinertz, T; Patten, M; Sonntag, F | 1 |
| Breithardt, G; Burschel, G; Engberding, R; Fetsch, T; Koch, HP; Lukl, J; Trappe, HJ; Treese, N | 1 |
| Bauman, J; Southworth, MR; Viana, M; Zarembski, D | 1 |
| Lewalter, T; Lüderitz, B | 1 |
| Dell'Orfano, JT; Luck, JC; Naccarelli, GV; Patel, HM; Wolbrette, DL | 1 |
| Allessie, MA; Dorland, R; Mast, F; Wijffels, MC | 1 |
| Singh, BN | 1 |
| Farkas, A; Leprán, I; Papp, JG | 1 |
| Fetsch, T | 1 |
| Bhatta, L; Hynes, J; Khan, M; Luck, J; Naccarelli, GV; Samii, S; Wolbrette, DL | 1 |
| Bulanova, NA; Kositsyna, IV; Morozova, MN; Tereshchenko, SN; Uteshev, IuA | 1 |
| Antzelevitch, C; Bianchi, F; Borggrefe, M; Brugada, R; Calò, L; Gaita, F; Giustetto, C; Haissaguerre, M; Schimpf, R; Wolpert, C | 1 |
| Borbély, M; Dani, G; Erdej, F; Hajdara, I; Katona, A; Márk, L; Nagy, E; Sziklai, G | 1 |
| Bauer, P; Breithardt, G; Engberding, R; Fetsch, T; Koch, HP; Lukl, J; Meinertz, T; Oeff, M; Seipel, L; Trappe, HJ; Treese, N | 1 |
| Bauer, P; Dluzniewski, M; Hatala, R; Lüderitz, B; Maas, R; Meinertz, T; Müller, HW; Opolski, G; Patten, M; Sonntag, F | 1 |
| Dorian, P; Humphries, KH; Kerr, CR; Steinbuch, M | 1 |
| Antz, M; Kuck, KH; Nitschmann, S | 1 |
| Scharf, C | 1 |
| Borggrefe, M; Breithardt, G; Eckardt, L; Milberg, P; Osada, N; Schimpf, R; Tegelkamp, R; Wolpert, C | 1 |
| Kaufman, ES | 1 |
| Braam, SR; Meyer, T; Mummery, CL; Passier, R; Tertoolen, L; van de Stolpe, A | 1 |
| Bonnemeier, H; Hescheler, J; Liang, H; Matzkies, M; Reppel, M; Schunkert, H; Tang, M | 1 |
| Cox, RH; Fromme, S; Guo, D; Guo, J; Kowey, PR; Patel, C; Quan, XQ; Sun, Y; Yan, GX; Zhang, L; Zhang, P | 1 |
| Dumotier, B; Guérard, N; Jordaan, P | 1 |
| Brugada, J; Brugada, P; Gussak, I | 1 |
| Hinoi, E; Miyawaki, I; Tsubouchi, T; Watanabe, K; Yamada, T | 1 |
| Bai, S; Cao, H; Chen, K; Dong, H; Ma, Y; Pei, J; Tian, L; Zhao, Y | 1 |
| Kawai, T; Kuninishi, Y; Muraki, Y; Nogawa, H | 1 |
| Jiang, M; Li, Z; Lu, W; Wang, S; Wang, X; Wei, Z; Yang, F; Zhang, S | 1 |
16 review(s) available for sotalol and quinidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Atrial fibrillation. Is there a safe and highly effective pharmacological treatment?
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Death, Sudden; Electric Countershock; Humans; Meta-Analysis as Topic; Quinidine; Sotalol | 1990 |
Effectiveness of sotalol for therapy of complex ventricular arrhythmias and comparisons with placebo and class I antiarrhythmic drugs.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Heart Ventricles; Humans; Multicenter Studies as Topic; Procainamide; Quinidine; Randomized Controlled Trials as Topic; Sotalol | 1990 |
Antiarrhythmic drug therapy of ventricular arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil | 1986 |
Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias.
Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Drug Therapy, Combination; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Myocardial Infarction; Oxprenolol; Physical Exertion; Propranolol; Quinidine; Receptors, Adrenergic; Sotalol; Tachycardia, Paroxysmal | 1970 |
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil | 1993 |
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Bepridil; Cardiovascular Agents; Disopyramide; Female; Humans; Male; Middle Aged; Prenylamine; Procainamide; Quinidine; Risk Factors; Sex; Sotalol; Syncope; Tachycardia, Ventricular; Torsades de Pointes | 1993 |
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; Electric Countershock; Flecainide; Humans; Propafenone; Quinidine; Recurrence; Sotalol | 1993 |
Is there a need for new antiarrhythmic drugs?
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Conduction System; Humans; Propafenone; Quinidine; Sotalol; Torsades de Pointes | 1996 |
Antiarrhythmic drug therapy in the treatment of atrial fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Electrophysiology; Flecainide; Humans; Ion Channels; Quinidine; Sotalol; Sulfonamides | 1996 |
Comparison of sotalol versus quinidine for maintenance of normal sinus rhythm in patients with chronic atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Humans; Quinidine; Secondary Prevention; Sotalol | 1999 |
Cost-effective management of acute atrial fibrillation: role of rate control, spontaneous conversion, medical and direct current cardioversion, transesophageal echocardiography, and antiembolic therapy.
Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit Analysis; Echocardiography, Transesophageal; Electric Countershock; Flecainide; Humans; Procainamide; Propafenone; Quinidine; Sotalol; Verapamil | 2000 |
Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Australia; Canada; Controlled Clinical Trials as Topic; Europe; Flecainide; Heart Conduction System; Heart Failure; Humans; Multicenter Studies as Topic; Myocardial Infarction; Phenethylamines; Propafenone; Quinidine; Sotalol; Sulfonamides; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; United States | 2003 |
[Chronic heart failure and atrial fibrilation: aspects of management].
Topics: Acute Disease; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Cardiotonic Agents; Clinical Trials as Topic; Digoxin; Electric Countershock; Heart Failure; Humans; Quinidine; Randomized Controlled Trials as Topic; Sotalol; Sympatholytics; Time Factors; Vasodilator Agents | 2003 |
[Atrial flutter and fibrillation].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Calcium Channel Blockers; Catheter Ablation; Clinical Trials as Topic; Disopyramide; Electric Countershock; Electrocardiography; Emergencies; Flecainide; Heart Rate; Humans; Middle Aged; Pacemaker, Artificial; Propafenone; Quinidine; Recurrence; Sotalol; Sulfonamides; Treatment Outcome; Vasodilator Agents | 2005 |
Quinidine in short QT syndrome: an old drug for a new disease.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Genetic Predisposition to Disease; Humans; Quinidine; Rabbits; Sotalol; Treatment Outcome | 2007 |
17 trial(s) available for sotalol and quinidine
| Article | Year |
|---|---|
Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Death, Sudden; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Heart Rate; Humans; Male; Middle Aged; Prognosis; Quinidine; Recurrence; Sotalol | 1990 |
Sotalol versus class I and II antiarrhythmic agents.
Topics: Arrhythmias, Cardiac; Double-Blind Method; Hemodynamics; Humans; Propranolol; Quinidine; Sotalol | 1990 |
Effectiveness of sotalol for therapy of complex ventricular arrhythmias and comparisons with placebo and class I antiarrhythmic drugs.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Heart Ventricles; Humans; Multicenter Studies as Topic; Procainamide; Quinidine; Randomized Controlled Trials as Topic; Sotalol | 1990 |
Enhanced efficacy of oral sotalol for sustained ventricular tachycardia refractory to type I antiarrhythmic drugs.
Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Drug Evaluation; Electrocardiography; Electrophysiology; Female; Follow-Up Studies; Heart Rate; Heart Ventricles; Humans; Long-Term Care; Male; Middle Aged; Monitoring, Physiologic; Procainamide; Quinidine; Random Allocation; Sotalol; Tachycardia | 1988 |
The hemodynamic effects of sotalol and quinidine: analysis by use of rest and exercise gated radionuclide angiography.
Topics: Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Female; Heart; Hemodynamics; Humans; Male; Middle Aged; Physical Exertion; Quinidine; Radionuclide Imaging; Random Allocation; Sotalol | 1987 |
Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: prospective comparison of sotalol versus quinidine.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Drug Administration Schedule; Electrocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Risk Factors; Sotalol; Time Factors | 1995 |
Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).
Topics: Acute Disease; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Quinidine; Sotalol; Tachycardia; Time Factors | 1995 |
Insights into the Electrophysiology Study Versus Electrocardiographic Monitoring Trial: its programmed stimulation protocol may introduce bias when assessing long-term antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Bias; Cardiac Pacing, Artificial; Drug Combinations; Electrocardiography, Ambulatory; Electrophysiology; Follow-Up Studies; Humans; Mexiletine; Procainamide; Quinidine; Research Design; Retrospective Studies; Sotalol; Tachycardia, Ventricular | 1995 |
[Sotalol and quinidine/verapamil (Cordichin) in chronic atrial fibrillation--conversion and 12-month follow-up--a randomized comparison].
Topics: Aged; Atrial Fibrillation; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Electric Countershock; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Long-Term Care; Male; Middle Aged; Quinidine; Sotalol; Verapamil | 1994 |
Sotalol and type IA drugs in combination prevent recurrence of sustained ventricular tachycardia.
Topics: Aged; Cardiac Pacing, Artificial; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Procainamide; Prospective Studies; Quinidine; Recurrence; Sotalol; Tachycardia, Ventricular; Treatment Outcome | 1993 |
[Analysis of atrial fibrillation recurrence during therapy with sotalol or quinidine. Researchers of +SOCESP].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Quinidine; Recurrence; Sotalol | 1998 |
[Medicamentous prevention of symptomatic paroxysmal atrial fibrillation/flutter onset. Goals and design of the SOPAT Study. Executive committee of the investigators representing trial physicians].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Electric Countershock; Electrocardiography, Ambulatory; Germany; Humans; Prospective Studies; Quinidine; Recurrence; Sotalol; Tachycardia, Paroxysmal; Telemetry; Treatment Outcome; Verapamil | 1999 |
[Medicamentous prevention after electric cardioversion of chronic atrial fibrillation. Goals and design of the PAFAC Study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Czech Republic; Double-Blind Method; Drug Combinations; Electric Countershock; Electrocardiography, Ambulatory; Female; Germany; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Sotalol; Telemetry; Verapamil | 1999 |
Efficacy and safety of sotalol versus quinidine for the maintenance of sinus rhythm after conversion of atrial fibrillation. SOCESP Investigators. The Cardiology Society of São Paulo.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Female; Heart Rate; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Recurrence; Sotalol; Treatment Outcome | 1999 |
Short QT syndrome: pharmacological treatment.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Female; Flecainide; Humans; Male; Quinidine; Sotalol; Syndrome; Treatment Outcome | 2004 |
Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Drug Therapy, Combination; Electric Countershock; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Secondary Prevention; Sotalol; Survival Analysis; Treatment Outcome; Verapamil | 2004 |
Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electrocardiography; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Sotalol; Survival Analysis; Tachycardia; Treatment Outcome; Verapamil | 2004 |
72 other study(ies) available for sotalol and quinidine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship | 1993 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Proceedings: Value of plasma level determinations of cardioactive drugs during therapy].
Topics: Digoxin; Drug Therapy; Humans; Quinidine; Sotalol | 1975 |
Electrophysiologic and hemodynamic effects of H 234/09 (almokalant), quinidine, and (+)-sotalol in the anesthetized dog.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Hemodynamics; Male; Myocardial Contraction; Propanolamines; Quinidine; Sotalol | 1992 |
Differential effects of the new class III antiarrhythmic agents almokalant, E-4031 and D-sotalol, and of quinidine, on delayed rectifier currents in guinea pig ventricular myocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; In Vitro Techniques; Muscles; Piperidines; Potassium; Potassium Channels; Propanolamines; Pyridines; Quinidine; Sotalol; Time Factors | 1992 |
Is pretransplant antiarrhythmic drug therapy a risk factor?
Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Cause of Death; Child; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; Mexiletine; Middle Aged; Postoperative Complications; Premedication; Propafenone; Quinidine; Sotalol; Survival Rate; Transplantation, Heterotopic | 1992 |
Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes.
Topics: Acecainide; Action Potentials; Animals; Electric Stimulation; Female; Guinea Pigs; Heart; Ion Channels; Male; Membranes; Myocardium; Papillary Muscles; Potassium Channels; Quinidine; Sotalol | 1990 |
Serial antiarrhythmic drug treatment to maintain sinus rhythm after electrical cardioversion for chronic atrial fibrillation or atrial flutter.
Topics: Actuarial Analysis; Aged; Amiodarone; Analysis of Variance; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Drug Administration Schedule; Electric Countershock; Female; Flecainide; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Quinidine; Recurrence; Sotalol | 1991 |
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, Ambulatory; Electrolytes; Electrophysiology; Female; Flecainide; Heart Block; Hypocalcemia; Lidocaine; Male; Propranolol; Quinidine; Sotalol | 1991 |
New hope in atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Quinidine; Sotalol | 1990 |
QT prolongation and arrhythmia suppression.
Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Deafness; Death, Sudden; Electrocardiography; Heart Atria; Heart Ventricles; Humans; Quinidine; Sotalol; Systole; Tachycardia | 1985 |
Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs.
Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Dogs; Female; Heart Conduction System; Lidocaine; Male; Neural Conduction; Ouabain; Physical Exertion; Propafenone; Quinidine; Refractory Period, Electrophysiological; Sotalol | 1988 |
Differential effect of some antiarrhythmic drugs in right- or left-sided aconitine-induced experimental atrial arrhythmias.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dogs; Female; Male; Propranolol; Quinidine; Sotalol; Verapamil | 1987 |
Pharmacologic conversion and suppression of experimental canine atrial flutter: differing effects of d-sotalol, quinidine, and lidocaine and significance of changes in refractoriness and conduction.
Topics: Animals; Atrial Flutter; Cardiac Pacing, Artificial; Dogs; Drug Evaluation; Electrocardiography; Electrophysiology; Heart Conduction System; Lidocaine; Neural Conduction; Quinidine; Refractory Period, Electrophysiological; Sotalol; Time Factors | 1986 |
Inhibition of quinidine-propranolol elevation of the ventricular fibrillation threshold by bilateral stellectomy+vagotomy in the anesthetized dog.
Topics: Anesthesia; Animals; Denervation; Dogs; Electric Stimulation; Female; Heart; Male; Propranolol; Quinidine; Sotalol; Stellate Ganglion; Vagotomy; Ventricular Fibrillation | 1986 |
The activity of beta-adrenoceptor blocking agents in protecting mice from the cardiotoxic effects of ouabain.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Anti-Arrhythmia Agents; Diazepam; Dose-Response Relationship, Drug; Electrocardiography; Ethanolamines; Lidocaine; Male; Mice; Mice, Inbred Strains; Nitrobenzenes; Ouabain; Phenethylamines; Propranolol; Propylamines; Quinidine; Sotalol | 1973 |
The effects of -blocking drugs on atrioventricular conduction and contractility.
Topics: Adrenergic beta-Antagonists; Animals; Dogs; Heart; Heart Conduction System; Oxprenolol; Propranolol; Quinidine; Sotalol; Sympatholytics | 1971 |
Comparative antiarrhythmic activity of quinidine combined with propranolol and with sotalol.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Dogs; Drug Interactions; Female; Heart Rate; Male; Propranolol; Quinidine; Sotalol; Ventricular Fibrillation | 1981 |
Sotalol-induced prolongation of the Q-T interval and attacks of unconsciousness.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Heart Ventricles; Humans; Middle Aged; Quinidine; Sotalol; Unconsciousness | 1984 |
Action potential prolongation exhibits simple dose-dependence for sotalol, but reverse dose-dependence for quinidine and disopyramide: implications for proarrhythmia due to triggered activity.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cesium; Disopyramide; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Microelectrodes; Purkinje Fibers; Quinidine; Sotalol | 1993 |
Cellular mechanism underlying the efficacy of the sotalol-quinidine combination.
Topics: Action Potentials; Animals; Drug Combinations; Electric Stimulation; Guinea Pigs; Muscle, Smooth, Vascular; Papillary Muscles; Quinidine; Sotalol; Tachycardia, Ventricular | 1993 |
Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Dilated; Drug Combinations; Female; Humans; Male; Middle Aged; Quinidine; Sotalol; Tachycardia; Torsades de Pointes; Ventricular Fibrillation | 1994 |
Absence of effects of class III antiarrhythmic agents on cloned cardiac K channels.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Cloning, Molecular; Electrophysiology; Myocardium; Oocytes; Piperidines; Potassium Channels; Pyridines; Pyrimidinones; Quinidine; Sotalol; Xenopus laevis | 1993 |
Differential effect of selected antiarrhythmic drugs on coronary artery ligation-induced ventricular arrhythmias on the right or left sides.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Disease Models, Animal; Dogs; Female; Ligation; Male; Propranolol; Quinidine; Sotalol; Tachycardia, Ventricular; Verapamil | 1995 |
Frequency-dependent electrophysiologic effects of d,l-sotalol and quinidine and modulation by beta-adrenergic stimulation.
Topics: Action Potentials; Administration, Oral; Adrenergic beta-Agonists; Analysis of Variance; Anti-Arrhythmia Agents; Autonomic Nervous System; Blood Pressure; Electrocardiography; Humans; Isoproterenol; Middle Aged; Prospective Studies; Quinidine; Sotalol; Tachycardia, Ventricular | 1996 |
Differential effects of antiarrhythmic agents on post-pause repolarization in cardiac Purkinje fibres.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Dose-Response Relationship, Drug; Phenethylamines; Potassium Channels; Purkinje Fibers; Quaternary Ammonium Compounds; Quinidine; Sodium Channels; Sotalol; Sulfonamides | 1996 |
Electrophysiologic mechanisms of antiarrhythmic efficacy of a sotalol and class Ia drug combination: elimination of reverse use dependence.
Topics: Action Potentials; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Procainamide; Quinidine; Sotalol; Tachycardia, Ventricular | 1997 |
Differential effects of D-sotalol, quinidine, and amiodarone on dispersion of ventricular repolarization in the isolated rabbit heart.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Heart Ventricles; In Vitro Techniques; Quinidine; Rabbits; Sotalol; Ventricular Function | 1997 |
Combination of sotalol and quinidine in a canine model of torsades de pointes: no increase in the QT-related proarrhythmic action of sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Therapy, Combination; Electrophysiology; Infusions, Intravenous; Quinidine; Sodium Chloride; Sotalol; Torsades de Pointes | 1998 |
Effects of dauricine, quinidine, and sotalol on action potential duration of papillary muscles in vitro.
Topics: Action Potentials; Alkaloids; Animals; Anti-Arrhythmia Agents; Benzylisoquinolines; Female; Guinea Pigs; In Vitro Techniques; Isoquinolines; Male; Papillary Muscles; Quinidine; Sotalol; Tetrahydroisoquinolines | 1997 |
Pharmacologic cardioversion of chronic atrial fibrillation in the goat by class IA, IC, and III drugs: a comparison between hydroquinidine, cibenzoline, flecainide, and d-sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Disease Models, Animal; Electrocardiography; Flecainide; Follow-Up Studies; Goats; Heart Conduction System; Imidazoles; Injections, Intravenous; Quinidine; Secondary Prevention; Sotalol; Treatment Outcome | 1999 |
[Paroxysmal atrial fibrillation].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Electric Countershock; Female; Humans; Middle Aged; Monitoring, Physiologic; Pacemaker, Artificial; Prognosis; Quinidine; Recurrence; Risk Factors; Sotalol; Thromboembolism; Vasodilator Agents | 2000 |
Widening of the excitable gap during pharmacological cardioversion of atrial fibrillation in the goat: effects of cibenzoline, hydroquinidine, flecainide, and d-sotalol.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Goats; Heart Conduction System; Imidazoles; Quinidine; Sotalol | 2000 |
CIBIS, MERIT-HF, and COPERNICUS trial outcomes: do they complete the chapter on beta-adrenergic blockers as antiarrhythmic and antifibrillatory drugs?
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Lidocaine; Quinidine; Sotalol; Survival Rate; Treatment Outcome | 2001 |
Proarrhythmic effects of intravenous quinidine, amiodarone, D-sotalol, and almokalant in the anesthetized rabbit model of torsade de pointes.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Electrocardiography; Heart Rate; Infusions, Intravenous; Male; Phenylephrine; Propanolamines; Quinidine; Rabbits; Sotalol; Torsades de Pointes | 2002 |
[Atrial fibrillation successfully converted. A new standard in the prevention of recurrence?].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Humans; Placebos; Quinidine; Randomized Controlled Trials as Topic; Recurrence; Sotalol; Time Factors; Verapamil | 2001 |
Atrial fibrillation: rate control often better than rhythm control.
Topics: Adult; Aged; Amiodarone; Anticoagulants; Arrhythmia, Sinus; Atrial Fibrillation; Canada; Disopyramide; Electric Countershock; Flecainide; Heart Rate; Humans; Netherlands; Platelet Aggregation Inhibitors; Propafenone; Quinidine; Sotalol; United States | 2004 |
[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiology Service, Hospital; Electric Countershock; Female; Follow-Up Studies; Hospital Departments; Humans; Hungary; Male; Middle Aged; Prajmaline; Propafenone; Quinidine; Retrospective Studies; Sotalol | 2004 |
Limitations to antiarrhythmic drug use in patients with atrial fibrillation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Contraindications; Female; Flecainide; Humans; Male; Middle Aged; Propafenone; Quinidine; Registries; Sotalol | 2004 |
[PAFAC Study. Secondary prevention of atrial fibrillation after cardioversion].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therapy, Combination; Electric Countershock; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Secondary Prevention; Sotalol; Survival Analysis; Treatment Outcome; Verapamil | 2005 |
Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Heart Conduction System; In Vitro Techniques; Pinacidil; Quinidine; Rabbits; Random Allocation; Refractory Period, Electrophysiological; Sotalol; Vasodilator Agents | 2007 |
Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes.
Topics: Animals; Cell Line; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Electrophysiology; Embryonic Stem Cells; Humans; Lidocaine; Long QT Syndrome; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Quinidine; Sotalol | 2010 |
Human and murine embryonic stem cell-derived cardiomyocytes serve together as a valuable model for drug safety screening.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Embryonic Stem Cells; Humans; Mice; Myocytes, Cardiac; Quinidine; Sotalol; Verapamil | 2010 |
A novel mutation in the KCNH2 gene associated with short QT syndrome.
Topics: Adolescent; Adult; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Genetic Testing; HEK293 Cells; Humans; Male; Middle Aged; Models, Molecular; Mutation; Pedigree; Phenotype; Quinidine; Sequence Analysis, DNA; Sotalol; Young Adult | 2011 |
Analysis of unipolar electrograms in rabbit heart demonstrated the key role of ventricular apicobasal dispersion in arrhythmogenicity.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Chromans; Electrophysiologic Techniques, Cardiac; Endocardium; Pericardium; Quinidine; Rabbits; Sotalol; Sulfonamides; Torsades de Pointes | 2014 |
Short QT syndrome: a predictable story.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Electrocardiography; Female; Humans; Male; Mutation; Quinidine; Risk Factors; Sotalol | 2014 |
Telemetered common marmosets is useful for the assessment of electrocardiogram parameters changes induced by multiple cardiac ion channel inhibitors.
Topics: Animals; Astemizole; Body Temperature; Calcium Channel Blockers; Callithrix; Electrocardiography; Flecainide; Male; Models, Animal; Quinidine; Risk Assessment; Sotalol; Telemetry; Terfenadine; Verapamil; Voltage-Gated Sodium Channel Blockers | 2019 |
Assessment of Drug Proarrhythmic Potential in Electrically Paced Human Induced Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes Using Multielectrode Array.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cations, Divalent; Cell Differentiation; Humans; Induced Pluripotent Stem Cells; Ion Transport; Microelectrodes; Models, Biological; Myocardial Contraction; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Phenethylamines; Primary Cell Culture; Quinidine; Sotalol; Sulfonamides; Tetrodotoxin; Verapamil | 2021 |
Pharmacological characterisation of electrocardiogram J-T
Topics: Animals; DNA-Binding Proteins; Electrocardiography; Flecainide; Guinea Pigs; Long QT Syndrome; Nifedipine; Quinidine; Quinine; Ranolazine; Sotalol; Torsades de Pointes; Verapamil | 2022 |
Computational analysis of arrhythmogenesis in KCNH2 T618I mutation-associated short QT syndrome and the pharmacological effects of quinidine and sotalol.
Topics: Action Potentials; Anti-Arrhythmia Agents; ERG1 Potassium Channel; Humans; Mutation; Quinidine; Sotalol | 2022 |