sotalol has been researched along with propranolol in 298 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 223 (74.83) | 18.7374 |
| 1990's | 26 (8.72) | 18.2507 |
| 2000's | 22 (7.38) | 29.6817 |
| 2010's | 20 (6.71) | 24.3611 |
| 2020's | 7 (2.35) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, K; Kasuya, Y; Obase, H; Shigenobu, K; Tatsuno, H | 1 |
| Davey, DD; Gomez, RP; Lind, JM; Lis, R; Marisca, AJ; Morgan, TK; Phillips, GB; Sullivan, ME | 1 |
| Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Baker, JG | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J | 1 |
| Bischoff-Kont, I; Chaikuad, A; Faudone, G; Fürst, R; Heering, J; Kaiser, A; Knapp, S; Merk, D; Rachor, L; Willems, S; Zhubi, R | 1 |
| Pfeifer, S; Zimmer, C | 1 |
| Hoffman, BF; Rosen, MR; Wit, AL | 1 |
| Salimi, M | 1 |
| Podolec, Z; Szczeklik, A | 1 |
| Donker, PJ; van der Sluis, C | 1 |
| Ramsay, I | 1 |
| O'Dea, RF; Zatz, M | 1 |
| Levy, JV | 1 |
| Brown, HC; Carruthers, SG; McDevitt, DG; Shanks, RG | 1 |
| Roch, P; Salamin, A | 1 |
| Meier, J | 1 |
| Levy, B; Sadagopa Ramanujam, VM; Trieff, NM; Venkatasubramanian, N; Young, TR | 1 |
| Frohlich, ED; Lohmöller, G; Lydtin, H | 1 |
| Clements, JA; Oyarzun, MJ | 1 |
| Day, MD; Roach, AG | 2 |
| Kiechel, JR; Meier, J | 1 |
| Sandrew, BB; Sharma, JN; Wang, SC | 1 |
| Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S | 1 |
| Abiko, Y; Ichihara, K; Ichihara, M | 1 |
| Gupta, RS; Jariwala, NU; Joshi, NJ; Kelkar, VV | 1 |
| Goshima, K | 2 |
| Navarro, G; Richardson, R; Zuban, AT | 1 |
| Diamond, BI; Havdala, HS; May, J; Sabelli, HC | 1 |
| Bylund, DB; Charness, ME; Snyder, SH | 1 |
| Kittel, E; Philippu, A | 1 |
| Abe, Y; Okahara, T; Yamamoto, K | 1 |
| Alpern, HP; Jackson, SJ | 1 |
| Buckner, CK; Muñoz-Ramírez, H; Ryan, CF | 1 |
| Baker, I; Das Gupta, DS; Sowton, E | 1 |
| Boissier, JR; Giudicelli, JF; Lhoste, F | 1 |
| Dubach, UC | 1 |
| Berglund, G | 1 |
| Nicholson, AN; Wright, CM | 1 |
| Davidheiser, S; Haugaard, ES; Haugaard, N | 1 |
| Anttila, M; Järvensivu, P; Pelkonen, RO; Sotaniemi, EA; Sundquist, H | 1 |
| Jefferson, D; Jenner, P; Marsden, CD | 1 |
| Brown, GJ; Cull, RE; Forfar, JC | 1 |
| Leahey, WJ; Neill, JD; Shanks, RG; Varma, MP | 2 |
| Anderson, R | 1 |
| Chopra, SC; Nag, DP; Sharma, PL | 1 |
| Larsen, A | 1 |
| Mathison, HJ; Mears, GJ; Van Petten, GR | 1 |
| Prichard, BN | 3 |
| Berger, HJ; Howe, BB; Mills, B; Winbury, MM; Winsor, T | 1 |
| Schorderet, MO; Schoredert-Slatkine, S | 1 |
| Kirsten, EB; Sharma, JN | 1 |
| Delini-Stula, A; Meier, M | 1 |
| Adolphson, RL; Townley, RG | 1 |
| Aramendía, P; Márquez, MT; Puntoni de Mikulic, LE | 1 |
| Desaulles, E; Imbs, JL; Kraetz, J; Schmidt, M; Schwartz, J | 1 |
| Toda, N | 2 |
| Cooling, MJ; Day, MD | 1 |
| Ferguson, HC; McKinney, GR; Perhach, JL | 1 |
| Garvey, HL; Ram, N | 1 |
| Arntzen, FC; Baksaas, I; Briseid, K; Korbu, A | 1 |
| Collste, P | 1 |
| Frierson, JL; Honig, CR | 1 |
| Allavena, A; Brambilla, G; Gazzaniga, GM; Martelli, A; Mazzei, M; Robbiano, L | 1 |
| Gitter, S; Gordon, I; Rehavi, M; Speiser, Z | 1 |
| Cheymol, G; Chézalviel, F; Davy, JM; Engel, F; Ertzbischoff, O; Lainée, P; Motté, G; Penin, E; Poirier, JM; Weissenburger, J | 1 |
| Barré, J; Cheymol, G; Cohen, A; Hugues, FC; Le Jeunne, C; Poirier, JM | 1 |
| Cheymol, G | 1 |
| Funck-Brentano, C; Roden, DM; Silberstein, DJ; Wood, AJ; Woosley, RL | 1 |
| Adan, AJ; Defauw, JA; Ernst, SM; Kingma, JH; Koomen, EM; Suttorp, MJ; Tjon Joe Gin, RM; van Hemel, NM | 1 |
| Hanyok, JJ; MacNeil, DJ | 1 |
| Bandyopadhyay, S; Klaunig, JE; Somani, P | 1 |
| Gomi, Y; Inagaki, O; Kasuya, Y; Ono, K; Suzuki, N | 1 |
| Abiko, Y; Ichihara, K; Sakai, K | 1 |
| Gelband, H; McCormack, J; Pickoff, AS; Stolfi, A; Villafane, J; Xu, H | 1 |
| Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR | 1 |
| Billette, J; Couture, R; Gendreau, R; Zhao, J | 1 |
| Abernethy, DR; Arendt, RM; Greenblatt, DJ | 1 |
| Chiba, S; Kobayashi, M; Shimotori, M | 1 |
| Fink, M; Lemmer, B; Ohm, T; Winkler, H | 1 |
| Allely, MC; Ungar, A | 1 |
| Brownlee, WC; Durrington, PN; Large, DM | 1 |
| Arendt, RM; Greenblatt, DJ; Mutschler, E; Ochs, HR; Schäfer-Korting, M | 1 |
| de Groot, G; de Wildt, D; Langemeijer, J; Sangster, B | 3 |
| Fishbein, L; Jackson, CD | 1 |
| Campeau, N; De Champlain, J; Godin, D; Lamontagne, D; Nadeau, R; Yamaguchi, N | 1 |
| Abila, B; Marshall, RW; Richens, A; Wilson, JF | 1 |
| Albengres, E; Duche, JC; Riant, P; Tillement, JP; Urien, S | 1 |
| de Champlain, J; Lamontagne, D; Nadeau, R; Naud, M; Yamaguchi, N | 1 |
| Alkondon, M; Ray, A; Sen, P | 1 |
| Hallberg, H | 1 |
| Catteau, J; Dumon, JP; Dupuis, B; Libert, C; Petit, H | 1 |
| Bouquet, S; Courtois, P; Fourtillan, JB; Joire, JE; Quehen, S; Saux, MC | 1 |
| Kasamatsu, T; Shirokawa, T | 1 |
| Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M | 1 |
| Kinlough-Rathbone, RL; Lalau Keraly, C; Mustard, JF; Vickers, JD | 1 |
| Grace, M; Klinke, WP; Kubac, G | 1 |
| Carlier, J; Deflandre, J; el Allaf, D; Gillard, V; Pirotte, J | 1 |
| Camm, AJ; Creamer, JE; Nathan, AW; Shennan, A | 1 |
| Gautam, CS; Lal, R; Pandhi, P; Sharma, PL | 1 |
| de Groot, G; de Wildt, DJ; Langemeijer, JJ; Sangster, B | 1 |
| Lawson, JW | 1 |
| Donaldson, R; Sutton, P; Taggart, P | 1 |
| Yamaguchi, N | 1 |
| Turner, P | 1 |
| Cheymol, G; Laubie, M; Mouillé, P; Schmitt, H | 2 |
| Bak, IJ; Grobecker, H; Hellenbrecht, D; Lemmer, B; Wiethold, G | 1 |
| Goldstein, RE | 1 |
| Górka, Z | 1 |
| Bonta, IL; Hall, DW | 1 |
| Endoh, M; Hashimoto, K; Kimura, T; Taira, N | 1 |
| Chiba, S; Hashimoto, K; Kubota, K; Taira, N | 1 |
| Grobecker, H; Hellenbrecht, D; Lemmer, B; Wiethold, G | 1 |
| Commarato, MA; Kaplan, HR | 1 |
| Frankl, WS; Lawrence, T | 1 |
| Truelove, JF; van Petten, GR; Willes, RF | 1 |
| Mylecharane, EJ; Raper, C | 2 |
| Bergamaschi, M; Caravaggi, AM; Mandelli, V; Shanks, RG | 1 |
| Lavender, MK; Parkes, MW | 1 |
| Hamilton, JT; Khan, MI; Manning, GW | 2 |
| Manninen, V | 1 |
| Hellenbrecht, D; Lemmer, B; Palm, D; Wiethold, G | 1 |
| Garteiz, DA; Walle, T | 1 |
| Daly, JW; Schultz, J | 1 |
| Epstein, SE; Goldstein, RE; Hall, CA | 1 |
| Ludden, CT; Minsker, DH; Scriabine, A; Stavorski, JM; Stone, CA; Torchiana, ML | 1 |
| Boakes, AJ; Boeree, BH | 1 |
| Braunwald, E; Gomoll, AW | 1 |
| Alter, WA; Priola, DV; Weiss, GK | 1 |
| Gettes, LS | 1 |
| Cheymol, G; Mouillé, P | 1 |
| Hodgins, DS; Kuo, JF; Kuo, WN | 1 |
| Afonso, S; Rowe, GG | 1 |
| Simpson, FO | 1 |
| Hasselbach, W; Makinose, M; Temple, DM | 1 |
| Janis, RA; Triggle, DJ | 1 |
| Jindal, MN; Kelkar, VV; Patel, VK; Shah, UH | 1 |
| Horii, D; Imai, S; Kawada, T; Takeda, K | 1 |
| Price, J; Whitlock, FA | 1 |
| Walle, T | 1 |
| Bauer, EW; DaVanzo, JP; Hahn, DW; Heilman, RD | 1 |
| Brann, EG; Maya, WE; Newman, DJ; Pendleton, RG; Sherman, SS | 1 |
| Austin, M; Fitzgerald, JD; Wale, JL | 1 |
| Bonorris, G; Chuck, L; Katz, JP; Parmley, WW; Rabinowitz, B | 1 |
| Blackburn, KJ; Burges, RA | 1 |
| Diamond, L | 1 |
| Elharrar, V; Nadeau, RA | 1 |
| Bourne, RK; Davis, WG | 1 |
| Advenier, C; Boissier, JR; Giudicelli, JF | 1 |
| Fitzgerald, JD; Wale, J | 1 |
| Roba, J | 1 |
| Leibowitz, SF | 1 |
| Bauer, EW; DaVanzo, JP; Heilman, RD | 1 |
| Cocchi, D; Mantegazza, P; Müller, EE | 1 |
| Saameli, K | 1 |
| Byon, KY; Fleckenstein, A; Grün, G; Kaufmann, R | 1 |
| De Schaepdryver, AF; Lambelin, G; Roba, J | 1 |
| Afonso, S; Berndt, TB; O'Brien, GS; Rowe, GG | 1 |
| Baum, T; Dinish, J; Eckfeld, DK; Metz, N; Peters, JR; Shropshire, AT; Varner, LL | 1 |
| Singh, BN | 1 |
| Diekema, A; Veninga, T | 1 |
| Duckles, SP; Nadel, JA; Rayner, MD | 1 |
| Ellis, S; Gothelf, B | 1 |
| Anton, AH; Goldberg, LI; Tjandramaga, TB; Toda, N | 1 |
| Awad, SA; Bruce, AW; Carro-Ciampi, G; Downie, JW; Lin, M; Marks, GS | 1 |
| Chiba, S; Hashimoto, K; Kubota, K; Tamura, K | 1 |
| Baile, CA; Krabill, LF; Martin, FH; Simpson, CW | 1 |
| Horn, ME; Prichard, BN | 1 |
| Share, NN | 1 |
| Burks, TF | 1 |
| De Champlain, J; Nadeau, RA; Tremblay, GM | 1 |
| Hanson, KM | 1 |
| Lockwood, RH; Lum, BK | 1 |
| Aviado, DM; Belej, MA | 1 |
| Buckner, CK; Christopherson, RC | 1 |
| Lefkowitz, RJ; Vatner, DE | 1 |
| Davis, LD; Koerpel, BJ | 1 |
| Green, KL | 1 |
| Lader, MH; Tyrer, PJ | 1 |
| Boucher, RC; Bromberg, PA; Gatzy, JT | 1 |
| Campbell, DG; Heyma, P; Larkins, RG | 1 |
| Jounela, AJ; Juustila, H; Lilja, M; Mattila, MJ | 1 |
| Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C | 1 |
| Garvey, HL; Woodhouse, BL | 1 |
| Giorgetti, F; Re, L; Rossini, L | 1 |
| Amess, J; Cole, P; Roberts, M; Taylor, EA; Trembath, PW; Turner, P | 1 |
| Lawson, JW; Wojciechowski, NJ | 1 |
| Alkondon, M; Bhatia, S; Sen, P; Sivam, SP | 1 |
| Buck, JD; Gross, GJ; Hardman, HF; Warltier, DC | 1 |
| Fish, A; Perucca, E; Pickles, H; Richens, A | 1 |
| Kudo, Y; Sokabe, H; Zehr, JE | 1 |
| Lessem, J | 1 |
| Brambach, U; Eibs, HG; Oberdisse, U | 1 |
| Gerstenbrand, F; Klingler, D; Poewe, W | 1 |
| Berte, LE; Clusin, WT; Echt, DS; Harrison, DC; Mason, JW; Samuelsson, RG | 1 |
| Amery, A; Bulpitt, C; Cattaert, A; Fagard, R; Staessen, J; Vanhees, L | 1 |
| Grey, AC; Henderson, AH; Lewis, MJ | 1 |
| Christensen, LK; Hansen, JM; Perrild, H; Skovsted, L | 1 |
| Merkle, W | 1 |
| Weisswange, A | 1 |
| Goldstein, S | 1 |
| Friedewald, WT; Frishman, WH; Furberg, CD | 2 |
| Lucchesi, BR; Patterson, E | 1 |
| Tomov, I | 1 |
| Arnold, JM; McDevitt, DG | 1 |
| Abed, J; Donaldson, R; Nashat, F; Taggart, P | 1 |
| Kanno, M; Kimura, S; Nakao, Y; Nakaya, H | 1 |
| Abernethy, DR; Arendt, RM; Bonin, JD; deJong, RH; Greenblatt, DJ | 1 |
| Battersby, LA; Cruickshank, JM; Prichard, BN | 1 |
| Black, JW; Jenkinson, DH; Kenakin, TP | 1 |
| Auclair, MC; Larno, S; Lechat, P; Lhoste, F | 1 |
| Alper, RH; Ganong, WF | 1 |
| Boukis, MA; Karaiskos, KS; Kitsopanides, J; Koutras, DA; Piperingos, GD; Souvatzoglou, A | 1 |
| Agnoletto, V; Casiglia, E; Dal Palu, C; Gava, R; Hlede, M; Locatelli, C; Morandin, F; Pessina, AC | 1 |
| Gross, GJ; Hardman, HF; Lamping, KG; Warltier, DC | 1 |
| Orme, ML | 1 |
| Boucek, RJ; Simpson, CF | 1 |
| Dahlöf, C; Engberg, G; Hallberg, H; Svensson, TH | 1 |
| Atkinson, JE; Diamond, L; Gillespie, MN; Turbek, JA | 1 |
| Anttila, M; Erkkola, R; Lammintausta, R; Liukko, P | 1 |
| Anttila, M; Aro, A; Korhonen, T; Sundquist, H | 1 |
| Anttila, M; Järvensivu, P; Rautio, A; Saukko, P; Sotaniemi, EA; Stengård, J | 1 |
| Blümchen, G; Esche, HH | 1 |
| Anttila, M; Pelkonen, RO; Pirttiaho, HI; Pitkänen, U; Sotaniemi, EA; Sundqvist, H | 1 |
| Schultz, HD; Zehr, JE | 1 |
| Fraedrich, G; Hasenfuss, G; Holubarsch, C; Just, H; Pieske, B; Posival, H; Ruf, T; Schneider, R | 1 |
| Andre, P; d'Ascanio, P; Manzoni, D; Pompeiano, O | 1 |
| McCollam, PL; Nappi, JM | 1 |
| Adamson, PB; Foreman, RD; Hull, SS; Schwartz, PJ; Vanoli, E | 1 |
| Buckley, NA; Dawson, AH; Epid, D; Reith, DM; Sayer, GP; Whyte, IM | 1 |
| Calders, P; Kint, J; Matthys, D; Pannier, JL | 1 |
| Gautam, CS; Pandhi, P; Sharma, PL | 1 |
| Schwartz, PJ | 1 |
| Carrupt, PA; Cheymol, G; Levron, JC; Poirier, JM; Snoeck, E; Testa, B; Weissenburger, J | 1 |
| Al Bunni, M; Ferrari, M; Gusella, M; Magnolfi, G; Maiolino, P; Padrini, R; Piovan, D; Zordan, R | 1 |
| Chang, MS; Chen, SA; Ding, YA; Feng, AN; Kuo, BI; Lee, SH; Tai, CT; Yu, WC | 1 |
| Hirvonen, J; Kontturi, K; Murtomäki, L | 1 |
| Kiesvaara, J; Kirjavainen, M; Mönkkönen, J; Urtti, A; Valjakka-Koskela, R | 1 |
| Cronhjort, M; Jacobsson, H; Jonsson, C | 1 |
| Akerman, S; Järvinen, K; Karhu, M; Paronen, P; Savolainen, J; Svarfvar, B; Tarvainen, T | 1 |
| Antzelevitch, C; Shimizu, W | 1 |
| Chang, MS; Chen, SA; Chen, YJ; Lin, CI | 1 |
| Suttorp, MJ; Tahapary, GJ | 1 |
| Cacciafesta, M; Di Giuseppe, V; Lionetti, M; Marigliano, V; Moisè, A; Naso, C; Nocco, M; Piccirillo, G | 1 |
| Banga, AK; Betageri, GV; Chaturvedula, A; Conjeevaram, R; Sunkara, G | 1 |
| Ali Shaik, A; Kamal, A; Sandbhor, M | 1 |
| Iwasaki, S; Kano, M; Kato, M; Ota, T; Shimizu, M; Toyoshi, T | 1 |
| Juvonen, R; Korhonen, LE; Pelkonen, O; Raunio, H; Tolonen, A; Turpeinen, M; Uusitalo, J | 1 |
| Ito, S; Kimura, K; Nakamura, M; Tabo, M | 1 |
| Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C | 1 |
| Alder, AC; Escher, BI; Maurer, M; Richle, P; Schaffner, C | 1 |
| Hara, T; Kimura, K; Kobayashi, K; Kuramoto, S; Nakano, K; Onodera, H; Shishido, N; Sone, S; Tabo, M | 1 |
| Mueller, D; Quirk, GJ; Rodriguez-Romaguera, J; Sotres-Bayon, F | 1 |
| Ma, M; Ouyang, L; Su, X; Xie, Q; Yao, S; Zhang, C; Zhang, L | 1 |
| Goodman, IS; Lu, CJ | 1 |
| Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y | 1 |
| Araujo Júnior, E; Bravo-Valenzuela, NJ; Peixoto, AB; Tonni, G | 1 |
| Chen, C; Ding, W; Du, Y; Ma, X; Sun, X; Tao, Y | 1 |
| Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B | 1 |
| Chen, YW; Hsu, CW; Huang, KY; Lin, CH; Lin, PY; Matsuoka, YJ; Stubbs, B; Su, KP; Tseng, PT; Tu, YK; Wu, YC | 1 |
| Bare, DJ; Bers, DM; Bossuyt, J; Dodge-Kafka, KL; Ginsburg, KS; Huynh, TN; Raofi, S; Shannon, TR; Van Dijk, S; Xiang, YK | 1 |
| He, Y; Lu, Y; Ruan, Y; Sun, H; Xu, J; Zhang, Y; Zhu, H | 1 |
| Guillon, E; Sayen, S; Smith, RM | 1 |
| Sun, H; Wang, Y; Xu, J; Zhang, W | 1 |
22 review(s) available for sotalol and propranolol
| Article | Year |
|---|---|
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Biotransformation and pharmacokinetics of beta-receptor blockaders].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Biotransformation; Ethanolamines; Humans; Isoproterenol; Kinetics; Levobunolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Sotalol | 1975 |
Electrophysiology and pharmacology of cardiac arrhythmias. IX. Cardiac electrophysiologic effects of beta adrenergic receptro stimulation and blockade. Part C.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Node; Dogs; Electrophysiology; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Membrane Potentials; Norepinephrine; Propranolol; Purkinje Fibers; Sinoatrial Node; Sotalol | 1975 |
[Comparative pharmacokinetics of beta-blockers].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol | 1978 |
Propranolol in the treatment of angina: a review.
Topics: Alprenolol; Angina Pectoris; Dose-Response Relationship, Drug; Heart Rate; Humans; Isosorbide; Practolol; Propranolol; Sotalol | 1976 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
Beta-adrenergic receptor blocking drugs in hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Alprenolol; Antithyroid Agents; Ethanolamines; Humans; Hyperthyroidism; Iodine Radioisotopes; Oxprenolol; Pindolol; Practolol; Premedication; Propranolol; Sotalol; Sympathomimetics; Thyroidectomy | 1974 |
A comparison of beta-blocking agents.
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Dogs; Dose-Response Relationship, Drug; Ethanolamines; Heart; Heart Rate; Humans; Oxprenolol; Propranolol; Propylamines; Sotalol | 1973 |
Beta-adrenergic receptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Aortic Aneurysm; Aortic Valve; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Coronary Circulation; Heart Diseases; Humans; Hypertension; Migraine Disorders; Neurasthenia; Nitroglycerin; Oxprenolol; Pheochromocytoma; Propranolol; Receptors, Adrenergic; Sotalol; Tetralogy of Fallot | 1973 |
Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias.
Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Drug Therapy, Combination; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Myocardial Infarction; Oxprenolol; Physical Exertion; Propranolol; Quinidine; Receptors, Adrenergic; Sotalol; Tachycardia, Paroxysmal | 1970 |
Beta-adrenergic receptor blocking drugs in angina pectoris.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Ethanolamines; Exercise Test; Heart Rate; Humans; Oxprenolol; Oxygen Consumption; Physical Exertion; Pindolol; Practolol; Propranolol; Sotalol | 1974 |
Beta-adrenergic receptor blocking drugs in hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Antidepressive Agents; Antihypertensive Agents; Asthma; Diuretics; Drug Evaluation; Drug Therapy, Combination; Ganglionic Blockers; Heart Failure; Humans; Hypertension; Libido; Oxprenolol; Pindolol; Practolol; Propranolol; Psychopharmacology; Regional Blood Flow; Sotalol; Vasodilator Agents | 1974 |
Use of beta-adrenergic receptor blocking drugs in psychiatry.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Anxiety; Chlordiazepoxide; Diazepam; Humans; Hyperventilation; Mental Disorders; Oxprenolol; Propranolol; Schizophrenia; Sotalol; Substance Withdrawal Syndrome; Substance-Related Disorders; Sympathetic Nervous System; Tremor | 1974 |
-Receptor antagonists in angina pectoris.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Heart Rate; Humans; Placebos; Propranolol; Sotalol; Sympatholytics | 1971 |
Anti-arrhythmic actions of -adrenergic receptor antagonists: review of fundamental aspects.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Digitalis Glycosides; Heart Conduction System; Humans; Indoles; Membrane Potentials; Myocardial Infarction; Propranolol; Refractory Period, Electrophysiological; Sotalol | 1972 |
Beta-adrenergic blockade for survivors of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
Overdosage with beta-adrenergic blocking agents.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Atropine; Blood Glucose; Cardiovascular System; Central Nervous System; Drug Tolerance; Heart Rate; Humans; Kinetics; Oxprenolol; Pindolol; Propranolol; Respiration; Sotalol | 1984 |
Sotalol: a breakthrough antiarrhythmic?
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrophysiology; Half-Life; Hemodynamics; Humans; Propranolol; Sotalol; Stereoisomerism; Tachycardia, Supraventricular | 1993 |
Do beta-adrenergic blocking agents increase asthma exacerbation? A network meta-analysis of randomized controlled trials.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Cardiovascular Diseases; Celiprolol; Disease Progression; Female; Humans; Incidence; Infusions, Intravenous; Male; Practolol; Propranolol; Randomized Controlled Trials as Topic; Risk; Sotalol; Status Asthmaticus; Timolol | 2021 |
34 trial(s) available for sotalol and propranolol
| Article | Year |
|---|---|
Comparative effects of beta adrenergic blocking drugs.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Oxprenolol; Pindolol; Placebos; Practolol; Propranolol; Sotalol | 1975 |
Antihypertensive effect of sotalol and propranolol a double-blind crossover study.
Topics: Blood Pressure; Clinical Trials as Topic; Heart Rate; Humans; Hypertension; Male; Middle Aged; Propranolol; Sotalol | 1977 |
beta-Adrenoreceptor antagonists in essential tremor.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Placebos; Propanolamines; Propranolol; Pulse; Sotalol; Tremor | 1979 |
Observations on some properties of a long-acting preparation of propranolol.
Topics: Adult; Delayed-Action Preparations; Half-Life; Heart Rate; Humans; Oxprenolol; Physical Exertion; Propranolol; Sotalol | 1979 |
Comparison of propranolol and sotalol pharmacokinetics in obese subjects.
Topics: Adult; Blood Pressure; Cardiac Output; Chromatography, High Pressure Liquid; Creatinine; Female; Heart Rate; Humans; Male; Middle Aged; Obesity; Orosomucoid; Propranolol; Sotalol | 1990 |
A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism.
Topics: Adult; Atenolol; Blood Pressure; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Male; Propranolol; Random Allocation; Receptors, Adrenergic, beta; Sotalol; Stereoisomerism | 1990 |
Efficacy and safety of low- and high-dose sotalol versus propranolol in the prevention of supraventricular tachyarrhythmias early after coronary artery bypass operations.
Topics: Administration, Oral; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Propranolol; Prospective Studies; Sotalol; Tachycardia, Supraventricular; Time Factors | 1990 |
Sotalol versus class I and II antiarrhythmic agents.
Topics: Arrhythmias, Cardiac; Double-Blind Method; Hemodynamics; Humans; Propranolol; Quinidine; Sotalol | 1990 |
Short-term effects of beta-adrenoceptor blocking drugs with and without cardioselectivity and intrinsic sympathomimetic activity on lipoprotein metabolism in hypertriglyceridaemic patients and in normal men.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Cholesterol; Cholesterol, HDL; Female; Half-Life; Heart Rate; Humans; Hyperlipoproteinemias; Lipoproteins; Lipoproteins, VLDL; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Sotalol; Triglycerides | 1985 |
Exercise-induced hand tremor: a possible test for beta 2-adrenoceptor selectivity in man?
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Hand; Heart Rate; Humans; Male; Physical Exertion; Propranolol; Receptors, Adrenergic, beta; Sotalol; Tremor | 1986 |
Comparison of propranolol, sotalol, and betaxolol in the treatment of neuroleptic-induced akathisia.
Topics: Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Betaxolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Propanolamines; Propranolol; Psychomotor Agitation; Sotalol | 1987 |
Randomized double blind trial comparing sotalol and propranolol in chronic ventricular arrhythmia.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Heart Ventricles; Humans; Male; Middle Aged; Propranolol; Random Allocation; Sotalol | 1988 |
Acute and chronic effects of sotalol and propranolol on ventricular repolarization using constant-rate pacing.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Pacemaker, Artificial; Propranolol; Random Allocation; Sotalol | 1986 |
-Receptor antagonists in angina pectoris.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Heart Rate; Humans; Placebos; Propranolol; Sotalol; Sympatholytics | 1971 |
Variable dose comparative trial of propranolol and sotalol in angina pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Humans; Propranolol; Sotalol | 1973 |
Central and peripheral effects of propranolol and sotalol in normal human subjects.
Topics: Adult; Electroencephalography; Female; Humans; Male; Noise; Placebos; Propranolol; Psychological Tests; Pulse; Self Concept; Skull; Sotalol; Sweating; Temporal Bone; Time Factors | 1972 |
Interaction of clonidine and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol | 1980 |
Duration of action of beta blockers.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol | 1980 |
The haemoglobin-oxygen dissociation curve: in vivo and in vitro effects of five beta-adrenoceptor antagonists and lignocaine.
Topics: Adrenergic beta-Antagonists; Adult; Erythrocytes; Hemoglobins; Humans; Lidocaine; Oxygen; Propranolol; Sotalol; Time Factors | 1981 |
Propranolol and sotalol as antagonists of isoproterenol-enhanced physiologic tremor.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Muscles; Propranolol; Sotalol; Tachycardia; Tremor | 1981 |
Beta-blocker therapy evaluated by radionuclide angiography: a study in chronic stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Cardiac Volume; Chronic Disease; Echocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propranolol; Radionuclide Imaging; Sotalol; Stroke Volume | 1982 |
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Oxprenolol; Practolol; Propranolol; Recurrence; Sotalol; Timolol | 1982 |
[Results with new beta receptor blockaders in the therapy of glaucoma].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Glaucoma; Humans; Levobunolol; Metipranolol; Penbutolol; Propranolol; Random Allocation; Sotalol | 1983 |
[Improved prognosis using beta blockers after myocardial infarct?].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Prognosis; Propranolol; Sotalol; Timolol | 1984 |
The Beta-Blocker Heart Attack Trial in perspective.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; Double-Blind Method; Female; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Norway; Placebos; Propranolol; Recurrence; Sotalol; Timolol | 1983 |
Beta-adrenergic blockade for survivors of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
Pharmacokinetics of propranolol and sotalol in hyperthyroidism.
Topics: Adult; Aged; Biological Availability; Female; Humans; Hyperthyroidism; Kinetics; Male; Middle Aged; Propranolol; Sotalol | 1982 |
Roles of hepatic blood flow and enzyme activity in the kinetics of propranolol and sotalol.
Topics: Adult; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Liver; Liver Circulation; Male; Middle Aged; Organ Size; Propranolol; Sotalol | 1980 |
[Prevention of sudden death in myocardial infarct: do experimental results help to understand the clinical reality? The case of the clinical trial SWORD (Survival With ORal D-sotalol)].
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Drug Therapy, Combination; Female; Humans; Isoproterenol; Male; Myocardial Infarction; Myocardial Ischemia; Propranolol; Sotalol; Survival Rate; Ventricular Fibrillation | 1996 |
Pharmacokinetics of beta-adrenoceptor blockers in obese and normal volunteers.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adult; Area Under Curve; Benzopyrans; Binding Sites; Bisoprolol; Blood Chemical Analysis; Blood Pressure; Cardiac Output; Chromatography, High Pressure Liquid; Ethanolamines; Female; Heart Rate; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Labetalol; Male; Nebivolol; Obesity; Propranolol; Regression Analysis; Sotalol; Stereoisomerism; Tissue Distribution | 1997 |
Tolerance to the repolarization effects of rac-sotalol during long-term treatment.
Topics: Action Potentials; Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Administration Schedule; Electrocardiography; Female; Heart; Heart Rate; Humans; Linear Models; Male; Middle Aged; Propranolol; Sotalol; Stereoisomerism | 1997 |
Tachycardia-induced change of atrial refractory period in humans: rate dependency and effects of antiarrhythmic drugs.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Electrophysiology; Female; Humans; Male; Middle Aged; Pacemaker, Artificial; Procainamide; Propafenone; Propranolol; Sotalol; Tachycardia, Supraventricular; Verapamil | 1998 |
246 other study(ies) available for sotalol and propranolol
| Article | Year |
|---|---|
Synthesis and adrenergic beta-blocking activity of some 1,3-benzodioxole derivatives.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxoles; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Methods; Myocardial Contraction; Rats | 1977 |
Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Chemical Phenomena; Chemistry, Physical; Dogs; Drug Design; Epinephrine; Heart Rate; In Vitro Techniques; Propanolamines; Purkinje Fibers; Receptors, Adrenergic, beta | 1990 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioblastoma; HEK293 Cells; Humans; Molecular Structure; Orphan Nuclear Receptors; Propranolol; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship | 2021 |
Comparison of beta-adrenoceptor blocking properties of sotalol, oxprenolol, propranolol and pindolol on rabbit intestinal smooth muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Oxprenolol; Pindolol; Propranolol; Rabbits; Sotalol | 1975 |
Central regulation of blood eosinophilia by the beta-adrenergic system in rats.
Topics: Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Cell Count; Blood-Brain Barrier; Eosinophilia; Eosinophils; Female; Hypophysectomy; Isoproterenol; Male; Practolol; Propranolol; Rats; Sotalol | 1976 |
Action of beta-adrenergic blocking agents on the urethral pressure profile.
Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Male; Middle Aged; Phentolamine; Pressure; Propranolol; Sotalol; Urethra | 1976 |
Adrenergic beta-receptor blockade in hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Humans; Hyperthyroidism; Propranolol; Sotalol | 1975 |
Catecholamine-stimulated cyclic GMP accumulation in the rat pineal: apparent presynaptic site of action.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Kinetics; Male; Melatonin; Norepinephrine; Ouabain; Pineal Gland; Potassium; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sotalol; Stereoisomerism; Synaptic Membranes | 1976 |
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors | 1976 |
Influence of intrinsic sympathomimetic activity and cardioselectivity on beta adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Humans; Male; Oxprenolol; Physical Exertion; Practolol; Propranolol; Sotalol; Sympathomimetics; Time Factors | 1977 |
Effect of beta-adrenergic drugs on adenosine 3', 5'-monophosphate in rabbit vagus nerve.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Brain; Cattle; Cyclic AMP; Epinephrine; Ganglia, Autonomic; Guinea Pigs; In Vitro Techniques; Isoproterenol; Organ Specificity; Propranolol; Rabbits; Sotalol; Theophylline; Vagus Nerve | 1977 |
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol | 1977 |
Structure-activity relationships of some selected beta-adrenergic blocking agents--oxidation with N-bromosuccinimide.
Topics: Adrenergic beta-Antagonists; Bromosuccinimide; Butoxamine; Dose-Response Relationship, Drug; Ethanolamines; Kinetics; Molecular Conformation; Pindolol; Practolol; Propranolol; Sotalol; Structure-Activity Relationship; Succinimides | 1976 |
[Antihypertensive and hemodynamic effects of beta-receptor blockaders with various action spectra].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Hemodynamics; Humans; Hypertension; Pindolol; Placebos; Practolol; Propranolol; Sotalol | 1976 |
Control of lung surfactant by ventilation, adrenergic mediators, and prostaglandins in the rabbit.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Indomethacin; Isoproterenol; Male; Meclofenamic Acid; Phenoxybenzamine; Phosphatidylcholines; Propranolol; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins H; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits; Respiration; Sotalol; Terbutaline | 1978 |
The brain as a possible site for the cardiovascular effects of beta-adrenoceptor blocking agents in cats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Blood Pressure; Brain; Cats; Female; Heart Rate; Injections, Intraventricular; Male; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol | 1975 |
CNS site of beta-adrenergic blocker-induced hypotension in the cat: a microiontophoretic study of bulbar cardiovascular neurones.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular System; Cats; Female; Iontophoresis; Male; Medulla Oblongata; Neurons; Propranolol; Sotalol; Time Factors | 1979 |
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol | 1979 |
Involvement of beta adrenergic receptors in decrease of myocardial pH during ischemia.
Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Female; Hydrogen-Ion Concentration; Isoproterenol; Male; Myocardium; Phentolamine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reserpine; Sotalol; Stereoisomerism; Sympathomimetics | 1979 |
Antagonism by some beta-adrenoceptor-blocking agents to cholinergic stimulation of skeletal muscle in vitro.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Anura; Ethanolamines; Guinea Pigs; Mesylates; Muscle Contraction; Muscles; Neuromuscular Junction; Nitriles; Practolol; Propranolol; Rana pipiens; Receptors, Cholinergic; Sotalol; Synaptic Transmission | 1979 |
Antagonistic influences of dibutyryl cyclic AMP and dibutyryl cyclic GMP on the beating rate of cultured mouse myocardial cells.
Topics: Bucladesine; Butyrates; Carbachol; Cells, Cultured; Cyclic GMP; Myocardial Contraction; Myocardium; Norepinephrine; Propranolol; Sotalol | 1976 |
Propranolol and morphine.
Topics: Animals; Lethal Dose 50; Male; Mice; Morphine; Propranolol; Receptors, Adrenergic, beta; Seizures; Sotalol | 1976 |
Differential interactions of phenobarbital and pentobarbital with beta-adrenergic mechanisms in vitro and in vivo.
Topics: Action Potentials; Animals; Anura; Bucladesine; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; In Vitro Techniques; Isoproterenol; Mice; Pentobarbital; Phenobarbital; Phentolamine; Propranolol; Rana pipiens; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sciatic Nerve; Seizures; Sotalol | 1977 |
Beta adrenergic receptor labeling in intact animals with 125I-hydroxybenzylpindolol.
Topics: Animals; Binding Sites; Brain Chemistry; Iodine Radioisotopes; Liver; Lung; Methods; Mice; Myocardium; Phentolamine; Pindolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol | 1977 |
Presence of beta-adrenoreceptors in the hypothalamus; their importance for the pressor response to hypothalamic stimulation.
Topics: Animals; Blood Pressure; Catheterization; Cats; Drug Interactions; Electric Stimulation; Female; Hypothalamus; Isoproterenol; Male; Metoprolol; Practolol; Procaine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol; Stereoisomerism; Tolazoline | 1977 |
Effects of dibutyryl cyclic AMP and propranolol on renin secretion in dogs.
Topics: Animals; Bucladesine; Cyclic AMP; Diuresis; Dogs; Glomerular Filtration Rate; Kidney; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Regional Blood Flow; Renin; Sotalol | 1977 |
Short-term memory: a neuropharmacologically distinct process.
Topics: Animals; Atropine; Ditiocarb; Male; Memory, Short-Term; Mice; Mice, Inbred C57BL; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Serotonin; Reversal Learning; Scopolamine; Sotalol | 1978 |
Studies on the temperature-dependent sensitivity of mouse atria to adrenergic drugs.
Topics: Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Synergism; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Mice; Nylidrin; Propranolol; Sotalol; Temperature | 1975 |
Beta-adrenergic blockade and atrio--ventricular conduction impairment.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atrioventricular Node; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Pindolol; Practolol; Propranolol; Refractory Period, Electrophysiological; Sotalol; Stereoisomerism | 1975 |
[Editorial: Importance of cardioselectivity and sympaticomimetric potential of beta-blockers (author's transl)].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Vessels; Ethanolamines; Heart; Humans; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Sympathomimetics | 1975 |
Behavioural studies in the monkey (Macaca mulatta) with sotalol and with (+)-, (+/-)- and (-)-propranolol [proceedings].
Topics: Animals; Behavior, Animal; Haplorhini; Macaca mulatta; Male; Propranolol; Sotalol; Stereoisomerism | 1977 |
Effects of epinephrine and the cyclic AMP phosphodiesterase inhibitor SQ 20009 on glucose and glycogen metabolism in skeletal muscle.
Topics: Animals; Calcium; Epinephrine; Etazolate; Glucose; Glucosephosphates; Glycogen; In Vitro Techniques; Male; Muscles; Nicotinic Acids; Phentolamine; Propranolol; Rats; Sotalol; Time Factors | 1979 |
Plasma clearance of propranolol and sotalol and hepatic drug-metabolizing enzyme activity.
Topics: Adult; Aged; Angina Pectoris; Antipyrine; Cytochrome P-450 Enzyme System; Female; Half-Life; Humans; Hypertension; Liver; Male; Middle Aged; Propranolol; Sotalol | 1979 |
Proximal myopathy during beta-blockade.
Topics: Aged; Angina Pectoris; Female; Humans; Muscular Diseases; Propranolol; Sotalol | 1979 |
Stimulation of normal and abnormal neutrophil motility in vitro by dexpropranolol, metoprolol and sotalol.
Topics: Adult; Cell Movement; Chemotaxis, Leukocyte; Female; Humans; In Vitro Techniques; Male; Metoprolol; Neutrophils; Propanolamines; Propranolol; Sotalol | 1979 |
Comparative study of propranolol, sotalol and INPEA in ouabain-induced cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Dogs; Ethanolamines; Female; Guinea Pigs; Male; Ouabain; Propranolol; Sotalol | 1977 |
Effects of pindolol, sotalol and the optical isomers of propranolol on muscle action potentials and depolarization-secretion coupling in the rat.
Topics: Action Potentials; Animals; Motor Endplate; Muscles; Neuromuscular Junction; Pindolol; Propranolol; Rats; Sotalol | 1978 |
Transfer of beta blocking drugs from the amniotic fluid to the fetal and maternal circulation.
Topics: Amniotic Fluid; Animals; Female; Fetal Heart; Fetus; Gestational Age; Heart Rate; Isoproterenol; Maternal-Fetal Exchange; Pregnancy; Propranolol; Sheep; Sotalol | 1978 |
Intramyocardial diversion of coronary blood flow: effects of isoproterenol-induced subendocardial ischemia.
Topics: Adult; Aged; Animals; Child; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Electrocardiography; Endocardium; Female; Humans; Ischemia; Isoproterenol; Isosorbide Dinitrate; Male; Middle Aged; Myocardium; Nitroglycerin; Oxygen; Propranolol; Rats; Regional Blood Flow; Retrospective Studies; Sotalol | 1975 |
[In vitro maturation of the ovocyte of Xenopus laevis under the effect of pharmacological agents related to propranolol].
Topics: Animals; Calcium; Cell Membrane; Female; Oocytes; Ovum; Progesterone; Propranolol; Sotalol; Xenopus | 1976 |
Characteristicas and response differences to iontophoretically applied norepinephrine, D-amphetamine and acetylcholine on neurons in the medial and lateral vestibular nuclei of the cat.
Topics: Acetylcholine; Action Potentials; Animals; Cats; Dextroamphetamine; Iontophoresis; Motion; Neural Inhibition; Neurons; Norepinephrine; Phentolamine; Propranolol; Reaction Time; Receptors, Adrenergic; Rotation; Sotalol; Vestibular Nuclei; Vestibular Nucleus, Lateral | 1976 |
Inhibitory effects of propranolol and oxprenolol on excitation induced by a MAO inhibitor and reserpine in the mouse.
Topics: Amphetamines; Animals; Male; Mice; Monoamine Oxidase Inhibitors; Motor Activity; Oxprenolol; Pargyline; Pindolol; Propranolol; Reserpine; Sotalol; Time Factors | 1976 |
A comparison of the beta-blocking activities of practolol, sotalol, and propranolol in human and guinea pig tracheal smooth muscle.
Topics: Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Humans; Isoproterenol; Mice; Muscle, Smooth; Practolol; Propranolol; Sotalol; Trachea | 1976 |
Metabolic responses to catecholamines.
Topics: Animals; Catecholamines; Dogs; Drug Interactions; Epinephrine; Hyperglycemia; Hyperkalemia; Hypokalemia; Isoproterenol; Metabolic Diseases; Muscles; Propranolol; Rats; Sotalol | 1976 |
beta-blocking drugs and renin secretion in the anaesthetized dog.
Topics: Animals; Aorta; Dogs; Electric Stimulation; Hemorrhage; Ischemia; Kidney; Propranolol; Renin; Sotalol | 1975 |
Nicotine-induced relaxation in isolated canine cerebral arteries.
Topics: Animals; Atropine; Bretylium Compounds; Cerebral Arteries; Cocaine; Dogs; Electric Stimulation; Female; Hexamethonium Compounds; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Nicotine; Ouabain; Potassium; Propranolol; Prostaglandins F; Sotalol; Sympathetic Nervous System | 1975 |
Drinking behaviour in the cat induced by renin, angiotensin I, II and isoprenaline.
Topics: Angiotensin II; Animals; Atropine; Bethanidine; Cats; Cerebral Ventricles; Drinking Behavior; Hexamethonium Compounds; Infusions, Parenteral; Isoproterenol; Pempidine; Phenoxybenzamine; Phentolamine; Practolol; Propranolol; Renin; Sotalol; Stimulation, Chemical; Tolazoline | 1975 |
Evaluation of antihypertensive agents in the stress-induced hypertensive rat.
Topics: Animals; Antihypertensive Agents; Chlorisondamine; Disease Models, Animal; Drug Evaluation, Preclinical; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Phentolamine; Propranolol; Rats; Sotalol; Stress, Physiological | 1975 |
Comparative antihypertensive effects and tissue distribution of beta adrenergic blocking drugs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Brain Chemistry; Female; Heart Rate; Injections, Subcutaneous; Liver; Lung; Male; Myocardium; Pindolol; Propranolol; Rats; Sotalol | 1975 |
Potentiation by beta-adrenoceptor blocking agents of the inhibitory effect of adrenaline on carrageenin-induced rat paw oedema.
Topics: Animals; Carrageenan; Catecholamines; Depression, Chemical; Drug Synergism; Edema; Epinephrine; Female; Male; Practolol; Propranolol; Rats; Sotalol; Stimulation, Chemical | 1975 |
Responses of isolated canine cerebral and peripheral arteries to nicotine.
Topics: Animals; Arteries; Bretylium Compounds; Cerebral Arteries; Cocaine; Dogs; Hexamethonium Compounds; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicotine; Phentolamine; Propranolol; Sotalol | 1975 |
[Dosage spacing in hypertension].
Topics: Humans; Hypertension; Pindolol; Practolol; Propranolol; Sotalol | 1976 |
Neurons intrinsic to arterioles initiate postcontraction vasodilation.
Topics: Animals; Arteries; Atropine; Blood Pressure; Denervation; Dipyridamole; Dogs; Gallamine Triethiodide; Hexamethonium Compounds; Lidocaine; Muscle Contraction; Neurons; Oxygen; Oxygen Consumption; Procaine; Propantheline; Propranolol; Regional Blood Flow; Sotalol; Vascular Resistance | 1976 |
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cell Survival; DNA; DNA Damage; DNA Repair; Humans; Liver; Male; Metoprolol; Nadolol; Nitrosamines; Nitrosation; Oxprenolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Nitrite; Sotalol | 1991 |
Behavioral and biochemical studies in rats following prenatal treatment with beta-adrenoceptor antagonists.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atenolol; Avoidance Learning; Birth Weight; Body Weight; Brain; Female; Gestational Age; Heart Rate; Male; Motor Activity; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sotalol | 1991 |
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, Ambulatory; Electrolytes; Electrophysiology; Female; Flecainide; Heart Block; Hypocalcemia; Lidocaine; Male; Propranolol; Quinidine; Sotalol | 1991 |
[Comparison of beta-blocking agents pharmacokinetics in obese and non-obese subjects].
Topics: Adrenergic beta-Antagonists; Adult; Bisoprolol; Female; Humans; Male; Obesity; Propanolamines; Propranolol; Sotalol | 1990 |
Cytotoxic interactions of cardioactive cationic amphiphilic compounds in primary rat hepatocytes in culture.
Topics: Amiodarone; Animals; Atenolol; Biomarkers; Cardiotonic Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Procainamide; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Verapamil | 1990 |
Propranolol blocks cocaine-induced potentiation of the contraction in the smooth muscle of the rat vas deferens.
Topics: Animals; Cocaine; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Vas Deferens | 1990 |
Effects of nicorandil and other antianginal drugs on myocardial pH in the ischemic dog heart.
Topics: Acidosis; Animals; Coronary Disease; Diltiazem; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Propranolol; Sotalol; Vasodilator Agents | 1987 |
Comparisons of the electrophysiological effects of intravenous sotalol and propranolol on the immature mammalian heart.
Topics: Analysis of Variance; Animals; Animals, Newborn; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Heart; Injections, Intravenous; Neural Conduction; Propranolol; Refractory Period, Electrophysiological; Sotalol | 1989 |
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure; Humans; Infant; Isoproterenol; Metoprolol; Mitral Valve Stenosis; Myocardium; Propranolol; Receptors, Adrenergic, beta; Sotalol; Tetralogy of Fallot | 1989 |
Intrinsic origin of atrioventricular nodal functional properties in rabbits.
Topics: Animals; Atrioventricular Node; Atropine; Autonomic Nervous System; Heart Conduction System; In Vitro Techniques; Propranolol; Rabbits; Sotalol | 1989 |
Pharmacologic properties of acebutolol: relationship of hydrophilicity to central nervous system penetration.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood-Brain Barrier; Cats; Cell Membrane; Dogs; Guinea Pigs; Hypertension; Lipid Metabolism; Propranolol; Solubility; Sotalol | 1985 |
Comparative study of five beta-adrenoceptor blocking agents on sinoatrial conduction time in isolated blood-perfused canine atria.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Carteolol; Dogs; In Vitro Techniques; Oxprenolol; Propranolol; Sinoatrial Node; Sotalol | 1985 |
Chronopharmacokinetics of beta-receptor blocking drugs of different lipophilicity (propranolol, metoprolol, sotalol, atenolol) in plasma and tissues after single and multiple dosing in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Chemical Phenomena; Chemistry, Physical; Half-Life; Heart Rate; Kinetics; Male; Metoprolol; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Structure-Activity Relationship; Time Factors; Tissue Distribution | 1985 |
Interactions of beta-adrenoceptor antagonists and thyroid hormones in the control of heart rate in the dog.
Topics: Adrenergic beta-Antagonists; Animals; Carbimazole; Dogs; Drug Interactions; Electrocardiography; Heart Conduction System; Heart Rate; Isoproterenol; Male; Nadolol; Propanolamines; Propranolol; Sotalol; Thyroid Hormones; Triiodothyronine | 1985 |
Single-dose kinetics of oral propranolol, metoprolol, atenolol, and sotalol: relation to lipophilicity.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Half-Life; Humans; Kinetics; Lipids; Male; Metoprolol; Propranolol; Solubility; Sotalol | 1985 |
Respiratory arrest as main determinant of toxicity due to overdose with different beta-blockers in rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Gas Analysis; Blood Pressure; Electrocardiography; Hemodynamics; Male; Propranolol; Rats; Rats, Inbred Strains; Respiratory Insufficiency; Sotalol; Timolol | 1985 |
Effects of sotalol, (-)-propranolol and prazosin on reperfusion-induced arrhythmias and increased cardiac norepinephrine release.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Catecholamines; Coronary Circulation; Creatine Kinase; Dogs; Female; Heart; Hemodynamics; Isoproterenol; Lactates; Male; Myocardium; Norepinephrine; Prazosin; Propranolol; Sotalol | 1986 |
Calcium interferes with the cardiodepressive effects of beta-blocker overdose in isolated rat hearts.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Catecholamines; Coronary Circulation; Electric Stimulation; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Timolol | 1986 |
High plasma protein binding as a parameter in the selection of betablockers for lactating women.
Topics: Acebutolol; Adrenergic beta-Antagonists; Blood Proteins; Female; Humans; Hypertension; Lactation; Milk, Human; Pindolol; Pregnancy; Propanolamines; Propranolol; Protein Binding; Sotalol | 1986 |
Presynaptic inhibitory effects of sotalol, propranolol, and acebutolol on noradrenaline release upon cardiac sympathetic nerve stimulation in anesthetized dogs.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Postganglionic; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart; Hemodynamics; Norepinephrine; Propranolol; Sotalol; Stellate Ganglion | 1986 |
Tissue cholinesterase inhibition by propranolol and related drugs.
Topics: Animals; Brain; Cholinesterase Inhibitors; Female; Male; Myocardium; Parasympathetic Nervous System; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Timolol | 1986 |
Blockade of central beta-adrenoceptors attenuates tremor induced by 5-hydroxytryptamine (5-HT)-receptor activation in rats.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Male; Methoxydimethyltryptamines; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sotalol; Tremor | 1987 |
[Tissue distribution of 3 beta-blockers in dogs].
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Dogs; Male; Propranolol; Sotalol; Tissue Distribution | 1987 |
Involvement of beta-adrenoreceptors in the shift of ocular dominance after monocular deprivation.
Topics: Anesthesia, Local; Animals; Brain Chemistry; Cats; Neuronal Plasticity; Propranolol; Receptors, Adrenergic, beta; Sensory Deprivation; Sotalol; Vision, Ocular; Visual Cortex | 1985 |
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Disease; Cyclic AMP; Electrocardiography; Female; Heart Rate; Lactates; Male; Metoprolol; Phosphates; Phosphocreatine; Propranolol; Sotalol; Swine; Time Factors; Ventricular Fibrillation | 1986 |
Involvement of phosphoinositide metabolism in potentiation by adrenaline of ADP-induced aggregation of rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Synergism; Epinephrine; Glycerol; In Vitro Techniques; Inositol Phosphates; Phentolamine; Phosphatidylinositols; Platelet Aggregation; Propranolol; Rabbits; Sotalol | 1987 |
[Effects of sotalol on blocked suprahepatic pressure in cirrhotic patients].
Topics: Aged; Blood Pressure; Cardiac Output; Cough; Female; Hepatic Veins; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Propranolol; Sotalol | 1987 |
Differential effect of some antiarrhythmic drugs in right- or left-sided aconitine-induced experimental atrial arrhythmias.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dogs; Female; Male; Propranolol; Quinidine; Sotalol; Verapamil | 1987 |
Central origin of respiratory arrest in beta-blocker intoxication in rats.
Topics: Animals; Blood-Brain Barrier; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Propranolol; Rats; Respiration; Respiratory Insufficiency; Sotalol; Tidal Volume; Timolol | 1987 |
Inhibition of quinidine-propranolol elevation of the ventricular fibrillation threshold by bilateral stellectomy+vagotomy in the anesthetized dog.
Topics: Anesthesia; Animals; Denervation; Dogs; Electric Stimulation; Female; Heart; Male; Propranolol; Quinidine; Sotalol; Stellate Ganglion; Vagotomy; Ventricular Fibrillation | 1986 |
d-Sotalol: a new potent class III anti-arrhythmic agent.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Endocardium; Female; Heart Block; Heart Rate; Male; Pericardium; Propranolol; Sotalol; Stereoisomerism | 1985 |
Effects of (+/-)-sotalol, (+/-)-propranolol, and (-)-propranolol on norepinephrine release upon hepatic nerve stimulation in the dog liver in vivo.
Topics: Animals; Blood Pressure; Dogs; Electric Stimulation; Isoproterenol; Liver; Liver Circulation; Male; Norepinephrine; Propranolol; Sotalol; Stereoisomerism | 1985 |
[Comparative study of chronotropic and inotropic effects of different beta adrenolytic drugs].
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Bradycardia; Dogs; Drug Antagonism; Female; Guinea Pigs; Heart; Heart Atria; Heart Conduction System; Heart Rate; Injections, Intramuscular; Injections, Intravenous; Male; Pindolol; Propranolol; Propylamines; Reserpine; Sotalol | 1972 |
Human blood platelets as cellular models for investigation of membrane active drugs: beta-adrenergic blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Biological Transport; Blood Platelets; Carbon Isotopes; Cell Membrane Permeability; Humans; Kinetics; Microscopy, Electron; Models, Biological; Oxprenolol; Pindolol; Propranolol; Serotonin; Serotonin Antagonists; Sotalol; Tritium | 1972 |
Analysis of the hemodynamic action of beta-adrenolytics in narcotized cats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cats; Chemical Phenomena; Chemistry; Female; Hemodynamics; Male; Oxprenolol; Pindolol; Propranolol; Sotalol | 1973 |
Effects of adrenergic blockers on the relaxation of the guinea-pig ileum by bradykinin and adrenaline.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bradykinin; Catecholamines; Drug Interactions; Drug Synergism; Duodenum; Epinephrine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Phentolamine; Propranolol; Rats; Sotalol | 1973 |
Comparison of new -andrenergic blockers, C-3, Kö1366, Y-6124 and YB-2, with pindolol and propranolol in the blood perfused canine papillary muscle preparation.
Topics: Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Dogs; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Norepinephrine; Papillary Muscles; Propranolol; Sotalol | 1972 |
Comparison of -adrenergic blocking activity of eight blockers in the excised and blood-perfused canine sino-atrial node preparation.
Topics: Adrenergic beta-Antagonists; Amino Alcohols; Animals; Coumarins; Dogs; Heart Rate; In Vitro Techniques; Nitriles; Norepinephrine; Propranolol; Sinoatrial Node; Sotalol | 1972 |
Measurement of hydrophobicity, surface activity, local anaesthesia, and myocardial conduction velocity as quantitative parameters of the non-specific membrane affinity of nine -adrenergic blocking agents.
Topics: 1-Propanol; Absorption; Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Anesthetics, Local; Animals; Anura; Butylamines; Cresols; Ethanolamines; Heart Conduction System; In Vitro Techniques; Membranes; Nitrobenzenes; Oxprenolol; Phenethylamines; Phenols; Pindolol; Propranolol; Propylamines; Sotalol; Structure-Activity Relationship; Surface Tension; Surface-Active Agents; Water | 1973 |
Relative beta adrenergic receptor blocking activity in dogs after intravenous and intraportal vein administration: bunolol, propranolol, their levo isomers and sotalol.
Topics: Adrenergic beta-Antagonists; Animals; Carbon Tetrachloride Poisoning; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Heart Rate; Injections, Intravenous; Levobunolol; Microsomes, Liver; Portal Vein; Proadifen; Propranolol; Sotalol; Stereoisomerism | 1973 |
Action of several -adrenoceptor blocking drugs in the pregnant sheep and foetus.
Topics: Acetals; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Ethanolamines; Female; Fetus; Heart Rate; Indenes; Isoproterenol; Levobunolol; Maternal-Fetal Exchange; Oxprenolol; Pregnancy; Propranolol; Sheep; Solubility; Sotalol; Time Factors | 1973 |
Further studies on the adrenergic neuron blocking activity of some -adrenoceptor antagonists and guanethidine.
Topics: Adrenergic beta-Antagonists; Amphetamine; Animals; Drug Interactions; Electric Stimulation; Guanethidine; Guinea Pigs; In Vitro Techniques; Isomerism; Male; Muscle Contraction; Neurons; Norepinephrine; Osmolar Concentration; Propranolol; Sotalol; Sympathetic Nervous System; Vas Deferens | 1973 |
The role of beta adrenoceptors in the coronary and systemic hemodynamic responses to emotional stress in conscious dogs.
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Acids; Anesthesia, Intravenous; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Catheterization; Coronary Circulation; Dogs; Electrocardiography; Emotions; Halothane; Heart Rate; Hemodynamics; Humans; Propranolol; Propylamines; Receptors, Adrenergic; Respiration, Artificial; Sotalol; Stress, Psychological; Thiopental | 1973 |
The activity of beta-adrenoceptor blocking agents in protecting mice from the cardiotoxic effects of ouabain.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Anti-Arrhythmia Agents; Diazepam; Dose-Response Relationship, Drug; Electrocardiography; Ethanolamines; Lidocaine; Male; Mice; Mice, Inbred Strains; Nitrobenzenes; Ouabain; Phenethylamines; Propranolol; Propylamines; Quinidine; Sotalol | 1973 |
Early arrhythmias following experimental coronary occlusion in conscious dogs and their modification by beta-adrenoceptor blocking drugs.
Topics: Acetanilides; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Consciousness; Coronary Disease; Coronary Vessels; Dogs; Electrocardiography; Heart Block; Heart Rate; Ligation; Propranolol; Propylamines; Sotalol; Tachycardia; Time Factors; Ventricular Fibrillation | 1973 |
Modified erythrocyte cation permeability.
Topics: Alprenolol; Butylamines; Cell Membrane Permeability; Erythrocytes; Ethanolamines; Humans; Kinetics; Naphthalenes; Nitrobenzenes; Phenethylamines; Potassium; Potassium Isotopes; Propranolol; Sodium; Sodium Isotopes; Sotalol; Stereoisomerism | 1972 |
Membrane effects of beta-adrenergic blocking agents: investigations with the fluorescence probe 1-anilino-8-naphthalene sulfonate (ANS) and antihemolytic activities.
Topics: Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Aniline Compounds; Binding Sites; Blood Proteins; Dose-Response Relationship, Drug; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Membranes; Naphthalenes; Pindolol; Propranolol; Sotalol; Spectrometry, Fluorescence; Sulfonic Acids | 1973 |
Electron impact fragmentation studies of beta-blocking drugs and their metabolites by GC-mass spectroscopy.
Topics: Acetates; Adrenergic beta-Antagonists; Alprenolol; Chemical Phenomena; Chemistry; Chromatography, Gas; Dealkylation; Fluorine; Isoproterenol; Mass Spectrometry; Oxprenolol; Propranolol; Sotalol; Structure-Activity Relationship | 1972 |
Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effects of alpha- and beta-adrenergic agents, histamine, serotonin and adenosine.
Topics: Adenosine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Cyclic AMP; Diphenhydramine; Epinephrine; Ergotamine; Guinea Pigs; Histamine; In Vitro Techniques; Isomerism; Male; Methysergide; Norepinephrine; Pheniramine; Phenoxybenzamine; Phentolamine; Propranolol; Serotonin; Sotalol; Xanthines | 1973 |
Comparison of relative inotropic and chronotropic effects of propranolol, practolol, and sotalol.
Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; Heart Rate; Isoproterenol; Male; Methods; Practolol; Propranolol; Receptors, Adrenergic; Reserpine; Sotalol; Stimulation, Chemical | 1973 |
[Inotropic effects of several adrenergic beta blockers in a dog subjected to electrosystolic cardiac impulse].
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Butylamines; Depression, Chemical; Dogs; Female; Heart Rate; Male; Nitriles; Pacemaker, Artificial; Pindolol; Practolol; Propanolamines; Propranolol; Sotalol; Stimulation, Chemical; Sulfides | 1973 |
Some cardiovascular effects of timolol a new beta-adrenergic blocking agent.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cats; Coronary Vessels; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Epinephrine; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Isoproterenol; Ligation; Male; Morpholines; Papillary Muscles; Propanolamines; Propranolol; Sclerosing Solutions; Sotalol; Thiadiazoles; Time Factors; Vascular Resistance | 1973 |
Letter: Suicidal attempts with beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Heart Rate; Humans; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Suicide | 1973 |
Comparative effects of sotalol and propranolol on myocardial contractility.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Chloride; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Extracorporeal Circulation; Heart; Heart Rate; Isoproterenol; Morphine; Propranolol; Reserpine; Sotalol | 1973 |
Vagally induced tachycardia in atropinized dogs: effect of beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Bretylium Compounds; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hexamethonium Compounds; Pentolinium Tartrate; Practolol; Propranolol; Sotalol; Stimulation, Chemical; Tachycardia; Vagus Nerve | 1973 |
[Action of various beta adrenolytic agents on the alpha blocking properties of yohimbine in the dog].
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Blood Pressure; Butylamines; Dogs; Epinephrine; Female; Heart Rate; Male; Nitriles; Pindolol; Propanolamines; Propranolol; Sotalol; Sulfides; Yohimbine | 1973 |
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium | 1974 |
Systemic and coronary hemodynamic effects of intracoronary administration of prostaglandins E1 and E2.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Coronary Circulation; Coronary Vessels; Hemodynamics; Injections, Intra-Arterial; Myocardium; Oxygen Consumption; Propranolol; Prostaglandins; Sotalol; Vascular Resistance; Vasodilator Agents | 1974 |
The inhibition by beta-adrenoceptor blocking agents of calcium uptake into and efflux from isolated sarcoplasmic vesicles.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Benzofurans; Biological Transport, Active; Calcium; Cytosine Nucleotides; Ethanolamines; Guanine Nucleotides; Hydrolysis; In Vitro Techniques; Inosine Nucleotides; Kinetics; Muscles; Oxprenolol; Practolol; Propranolol; Propylamines; Rabbits; Sarcoplasmic Reticulum; Sotalol; Uracil Nucleotides | 1974 |
On the reversal by (plus) and (minus)-propranolol of irreversible alpha-adrenoceptor blockade in rabbit aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding Sites; Bromine; Carboxylic Acids; Dimethylamines; Ethyl Ethers; In Vitro Techniques; Isomerism; Isoquinolines; Methylamines; Muscle Contraction; Mustard Compounds; Naphthalenes; Norepinephrine; Phenethylamines; Phenoxybenzamine; Propranolol; Rabbits; Sotalol | 1974 |
Central actions of some beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Animals; Body Temperature; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Ethanolamines; Ethers; Indenes; Isoproterenol; Mice; Morphine; Nicotine; Nitrobenzenes; Pentobarbital; Pentylenetetrazole; Phenethylamines; Practolol; Propanolamines; Propranolol; Rats; Reaction Time; Sotalol; Strychnine | 1974 |
Comparison of beta-adrenergic blocking activities of propranolol, isopropylmethoxamine, sotalol, practolol, alprenolol, pindolol, oxprenolol and D-32 in the atria and trachea of the guinea-pig.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Butylamines; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Oxprenolol; Phenyl Ethers; Pindolol; Practolol; Propanolamines; Propranolol; Receptors, Drug; Sotalol; Trachea | 1974 |
Nitrilophenoxypropanolamines: influence of ring substitution on beta-receptor blockade.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Rate; Isoproterenol; Male; Nitriles; Phenyl Ethers; Propanolamines; Propranolol; Rats; Receptors, Adrenergic; Sotalol; Stimulation, Chemical; Structure-Activity Relationship; Trachea | 1974 |
GLC determination of propranolol, other beta-blocking drugs, and metabolites in biological fluids and tissues.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Body Fluids; Chromatography, Gas; Ethanolamines; Fluoroacetates; Humans; Isoproterenol; Mass Spectrometry; Myocardium; Oxprenolol; Practolol; Propranolol; Rats; Sotalol | 1974 |
A comparison of cardiovascular and oviduct beta adrenergic receptors.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carotid Arteries; Drug Antagonism; Fallopian Tubes; Female; Isoproterenol; Perfusion; Phentolamine; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Drug; Sotalol; Stimulation, Chemical | 1972 |
Effect of propranolol upon the hemoglobin-oxygen dissociation curve.
Topics: 1-Propanol; Adenosine Triphosphate; Adrenergic beta-Antagonists; Adult; Amino Alcohols; Cresols; Erythrocytes; Female; Glycerophosphates; Hemoglobins; Humans; Male; Nitrobenzenes; Oxygen Consumption; Phenethylamines; Phenols; Propranolol; Propylamines; Protein Binding; Sotalol; Stereoisomerism; Structure-Activity Relationship | 1972 |
The haemodynamic effects of ( )-propranolol, dexpropranolol, oxprenolol, practolol and sotalol in anaesthetised dogs.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Blood Pressure; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; Hemodynamics; Male; Oxprenolol; Propranolol; Propylamines; Reserpine; Sotalol; Stereoisomerism; Sulfonamides; Sympatholytics | 1972 |
Comparative effects of sotalol and propranolol on contractility of papillary muscles and adenyl cyclase activity of myocardial extracts of cat.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Cats; Chromatography, Paper; Drug Interactions; Electric Stimulation; In Vitro Techniques; Isoproterenol; Muscle Contraction; Myocardium; Norepinephrine; Osmolar Concentration; Papillary Muscles; Propranolol; Reserpine; Sotalol; Sympatholytics | 1972 |
Adenyl cyclase and the differentiation of -adrenoreceptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Duodenum; Enzyme Activation; Epinephrine; Guinea Pigs; Isoproterenol; Lung; Male; Myocardium; Norepinephrine; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Receptors, Drug; Sotalol; Trachea | 1972 |
Potentiation of bronchomotor responses by beta adrenergic antagonists.
Topics: Acetanilides; Adrenergic beta-Antagonists; Airway Resistance; Amino Alcohols; Animals; Blood Pressure; Bronchi; Bronchial Spasm; Dogs; Drug Synergism; Female; Guanethidine; Guinea Pigs; Heart Rate; Histamine; Male; Nitrobenzenes; Oxprenolol; Phenethylamines; Propranolol; Propylamines; Respiratory Function Tests; Sotalol; Spirometry; Sympathectomy; Sympatholytics | 1972 |
Evaluation of -adrenergic blocking agents in presence of adrenergic tone.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Autonomic Fibers, Postganglionic; Biological Transport; Blood Pressure; Coronary Vessels; Dogs; Heart Rate; Injections, Intra-Arterial; Norepinephrine; Oxprenolol; Propranolol; Propylamines; Sinoatrial Node; Sotalol; Stellate Ganglion; Sympatholytics | 1972 |
The effects of corticosteroids on the reduction of -adrenoceptor blockade produced by -adrenoceptor blocking agents.
Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Blood Pressure; Cortisone; Desoxycorticosterone; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Sotalol; Sympatholytics | 1972 |
Comparative study of six -adrenoceptive antagonists on airway resistance and heart rate in the guinea-pig.
Topics: Acetanilides; Adrenergic beta-Antagonists; Airway Resistance; Alcohols; Animals; Bradycardia; Bronchi; Guinea Pigs; Heart Rate; Male; Muscles; Propranolol; Sotalol; Sympatholytics | 1972 |
The effects of -blocking drugs on atrioventricular conduction and contractility.
Topics: Adrenergic beta-Antagonists; Animals; Dogs; Heart; Heart Conduction System; Oxprenolol; Propranolol; Quinidine; Sotalol; Sympatholytics | 1971 |
Cardiac toxicity of -lytic drugs.
Topics: 1-Propanol; Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Cresols; Ethanolamines; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Indoles; Muscle Contraction; Nitrobenzenes; Oxprenolol; Papaverine; Phenethylamines; Prenylamine; Propranolol; Propylamines; Sotalol; Sympatholytics; Verapamil | 1972 |
Central adrenergic receptors and the regulation of hunger and thirst.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amphetamine; Animals; Anorexia Nervosa; Chlorpromazine; Drinking Behavior; Epinephrine; Feeding Behavior; Fenfluramine; Humans; Hunger; Hypothalamus; Isoproterenol; Motivation; Norepinephrine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Drug; Sotalol; Thirst | 1972 |
Effect of polyethylene glycol on the cardiovascular response of the dog to autonomic agents.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Autonomic Agents; Blood Pressure; Carotid Arteries; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Ganglionic Blockers; Glycols; Hindlimb; Histamine; Isoproterenol; Norepinephrine; Perfusion; Phenylephrine; Piperazines; Polyethylenes; Propranolol; Sotalol | 1972 |
Brain adrenergic system in the feeding response induced by 2-deoxy-D-glucose.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antimetabolites; Autonomic Fibers, Postganglionic; Brain; Cerebral Ventricles; Drug Combinations; Feeding Behavior; Female; Glucose; Hydroxydopamines; Injections; Phentolamine; Propranolol; Rats; Sotalol; Sympathectomy; Tyrosine | 1972 |
Pharmacological characterisation of -receptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cats; Ethanolamines; Guinea Pigs; Heart Rate; Isoproterenol; Pindolol; Propranolol; Sotalol | 1972 |
Protective effect of beta adrenoceptor blockade in experimental coronary occlusion in conscious dogs.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Coronary Disease; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Isoproterenol; Ligation; Membranes; Propranolol; Propylamines; Sotalol; Tachycardia; Ventricular Fibrillation | 1972 |
[Differentiation between beta adrenergic and Ca 2+ antagonistic influencing components of beta receptor blockaders in the myocardium and in smooth muscles with special reference to Trasicor].
Topics: Adrenergic beta-Antagonists; Allyl Compounds; Amino Alcohols; Animals; Calcium; Cats; Chick Embryo; Female; Guinea Pigs; Heart; Muscle Contraction; Muscle, Smooth; Papillary Muscles; Pindolol; Potassium; Prenylamine; Propranolol; Propylamines; Rabbits; Rats; Sotalol; Uterus; Verapamil | 1972 |
Antihypertensive activity of four blocking agents in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Disease Models, Animal; Heart Rate; Hydralazine; Hypertension; Male; Propranolol; Rats; Sotalol | 1972 |
Systemic and coronary hemodynamic effects of pronethalol practolol, sotalol and D-propranolol.
Topics: Acetanilides; Amino Alcohols; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Ethanolamines; Heart Rate; Hemodynamics; Indicator Dilution Techniques; Oxygen Consumption; Propranolol; Propylamines; Sotalol | 1972 |
Elevation of ventricular fibrillatory threshold by beta-adrenergic blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Anti-Arrhythmia Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Ethanolamines; Levobunolol; Male; Propranolol; Sotalol; Ventricular Fibrillation | 1972 |
Elevation of body temperature in rabbits by x-irradiation of the trunk.
Topics: Adrenal Glands; Adrenalectomy; Animals; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Radiation; Ergotamine; Hypothalamus; Leukocytes; Phentolamine; Propranolol; Rabbits; Radiation Effects; Sotalol; Theophylline; Time Factors | 1974 |
Effects of CO2 and pH on drug-induced contractions of airway smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Bethanechol Compounds; Bronchi; Calcium; Carbachol; Carbon Dioxide; Cats; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Methacholine Compounds; Methysergide; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Physostigmine; Potassium; Propranolol; Serotonin; Serotonin Antagonists; Sotalol; Tetrodotoxin | 1974 |
Effects of propanolol and sotalol on epinephrine-induced hyperglycemia and glycogen depletion of liver and muscle in the rat.
Topics: Animals; Blood Glucose; Epinephrine; Fasting; Female; Glycogen; Hyperglycemia; Injections, Intraperitoneal; Liver Glycogen; Muscles; Propranolol; Rats; Sotalol | 1974 |
Continuing studies of the peripheral vascular actions of dopamine.
Topics: Animals; Barium; Basilar Artery; Constriction; Coronary Vessels; Dilatation; Dogs; Dopamine; Femoral Artery; Heart; Levodopa; Mesenteric Arteries; Phenoxybenzamine; Propranolol; Prostaglandin Antagonists; Receptors, Drug; Renal Artery; Sotalol; Structure-Activity Relationship; Vasodilator Agents; Vasopressins | 1974 |
Distribution of alpha- and beta-adrenoceptors in human urinary bladder.
Topics: Acetylcholine; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phenylephrine; Propranolol; Receptors, Adrenergic; Sotalol; Sympathomimetics; Urinary Bladder | 1974 |
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors | 1974 |
Pharmacologic analysis of nicotine and dimethylphenylpiperazinium on pacemaker activity of the SA node in the dog.
Topics: Animals; Atropine; Blood Pressure; Depression, Chemical; Dimethylphenylpiperazinium Iodide; Dogs; Female; Ganglionic Stimulants; Heart Rate; Hexamethonium Compounds; Male; Nicotine; Perfusion; Piperazines; Propranolol; Sinoatrial Node; Sotalol; Stimulation, Chemical; Tetrodotoxin | 1972 |
Adrenergic agonists and antagonists and feeding in sheep and cattle.
Topics: Animals; Cattle; Cerebral Ventricles; Dose-Response Relationship, Drug; Feeding Behavior; Hypothalamus; Isoproterenol; Norepinephrine; Phenoxybenzamine; Propranolol; Sheep; Sotalol; Stereoisomerism; Stereotaxic Techniques; Structure-Activity Relationship | 1972 |
"Alpha" and "beta" adrenergic receptors in the medullary vasomotor center of the cat.
Topics: Animals; Blood Pressure; Cats; Electric Stimulation; Epinephrine; Ergoloid Mesylates; Female; Heart Rate; Male; Medulla Oblongata; Piperidines; Propranolol; Reticular Formation; Sotalol; Sympatholytics; Time Factors; Ulnar Nerve | 1973 |
Central alpha adrenergic receptors in thermoregulation.
Topics: Animals; Body Temperature Regulation; Cats; Cerebral Ventricles; Injections; Norepinephrine; Phentolamine; Practolol; Propranolol; Receptors, Adrenergic; Sotalol; Time Factors | 1972 |
Effects of d,l-propranolol, d-propranolol, l-propranolol, and sotalol on myocardial contractility and coronary resistance.
Topics: Animals; Blood Pressure; Coronary Vessels; Dose-Response Relationship, Drug; Electrodes, Implanted; Heart; Heart Ventricles; In Vitro Techniques; Isomerism; Perfusion; Propranolol; Rats; Sotalol; Vascular Resistance | 1973 |
Response of intrahepatic vasculature to isoproterenol and epinephrine influsions.
Topics: Animals; Blood Pressure; Catecholamines; Dilatation; Dogs; Epinephrine; Femoral Vein; Hepatic Artery; Infusions, Parenteral; Isoproterenol; Liver; Liver Circulation; Portal Vein; Propranolol; Regional Blood Flow; Sotalol; Time Factors; Vascular Resistance | 1973 |
Initiation of beating in quiescent myocardial cells by norepinephrine, by contact with beating cells and by electrical stimulation of adjacent FL cells.
Topics: Animals; Cell Separation; Cells, Cultured; Chick Embryo; Electric Stimulation; Electrophysiology; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Mice; Myocardium; Norepinephrine; Propranolol; Sotalol; Stimulation, Chemical | 1974 |
Effects of adrenergic agonists and antagonists on potassium metabolism.
Topics: Albuterol; Animals; Blood Glucose; Blood Pressure; Butoxamine; Cats; Epinephrine; Ethanolamines; Heart Rate; Hyperkalemia; Isoproterenol; Norepinephrine; Pancreas; Phenethylamines; Phenoxybenzamine; Phenylephrine; Potassium; Potassium Chloride; Practolol; Propanolamines; Propranolol; Propylamines; Sotalol; Sulfonamides; Sympatholytics; Sympathomimetics; Thiazoles; Time Factors; Toluene | 1974 |
Toxicity of aerosol propellants on the respiratory and circulatory systems. I. Cardiac arrhythmia in the mouse.
Topics: Aerosol Propellants; Aerosols; Animals; Arrhythmias, Cardiac; Atropine; Electrocardiography; Heart Block; Hydrocarbons, Chlorinated; Hydrocarbons, Fluorinated; Male; Mice; Propranolol; Sotalol; Vinyl Compounds | 1974 |
Adrenergic receptors of rat esophageal smooth muscle.
Topics: Animals; Carbachol; Cocaine; Dose-Response Relationship, Drug; Esophagus; Female; Isoproterenol; Muscle, Smooth; Phentolamine; Phenylephrine; Practolol; Propranolol; Rabbits; Receptors, Adrenergic; Sotalol | 1974 |
(3H)-Propranolol binding sites in myocardial membranes: nonidentity with beta adrenergic receptors.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Butoxamine; Catecholamines; Chlorpromazine; Dogs; Enzyme Activation; Haloperidol; In Vitro Techniques; Isoproterenol; Membranes; Myocardium; Nylidrin; Parasympathomimetics; Phentolamine; Phosphorus Radioisotopes; Propranolol; Receptors, Adrenergic; Sotalol; Structure-Activity Relationship; Time Factors; Tritium | 1974 |
Effects of lidocaine, propranolol, and sotalol on ouabain-induced changes in transmembrane potential of canine Purkinje fibers.
Topics: Action Potentials; Amino Alcohols; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Dogs; Heart Conduction System; In Vitro Techniques; Lidocaine; Membrane Potentials; Ouabain; Papillary Muscles; Propranolol; Sotalol; Sympatholytics | 1972 |
The anti-inflammatory effect of catecholamines in the peritoneal cavity and hind paw of the mouse.
Topics: Adrenalectomy; Amino Alcohols; Animals; Anti-Inflammatory Agents; Blood Glucose; Bradykinin; Capillary Permeability; Catecholamines; Dihydroxyphenylalanine; Dopamine; Edema; Epinephrine; Hindlimb; Histamine; Hydrocortisone; Insulin; Isoproterenol; Mice; Nitrobenzenes; Norepinephrine; Peritoneal Cavity; Phenoxybenzamine; Propranolol; Sotalol; Sympatholytics | 1972 |
Airway transepithelial electric potential in vivo: species and regional differences.
Topics: Acetylcholine; Amphotericin B; Animals; Atropine; Dogs; Electrophysiology; Epinephrine; Epithelium; Female; Guinea Pigs; Histamine; Isoproterenol; Male; Neurotransmitter Agents; Phentolamine; Phenylephrine; Propranolol; Rabbits; Sotalol; Species Specificity; Trachea | 1980 |
Inhibition by propranolol of 3,5,3'-triiodothyronine formation from thyroxine in isolated rat renal tubules: an effect independent of beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Kidney Tubules; Propranolol; Rats; Sotalol; Thyroxine; Triiodothyronine | 1980 |
Reversal of clonidine-induced hypotension by beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Female; Heart Rate; Hypertension; Male; Propranolol; Rabbits; Rats; Sotalol; Time Factors | 1980 |
[Cholinergic antagonism by beta-blockers. I. Spectrum of interactions].
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Ileum; Isoproterenol; Labetalol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Receptors, Cholinergic; Sotalol | 1980 |
Comparative antiarrhythmic activity of quinidine combined with propranolol and with sotalol.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Dogs; Drug Interactions; Female; Heart Rate; Male; Propranolol; Quinidine; Sotalol; Ventricular Fibrillation | 1981 |
Anticholinesterase effect of sotalol.
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinesterase Inhibitors; In Vitro Techniques; Metoprolol; Muscle Contraction; Physostigmine; Practolol; Propranolol; Ranidae; Sotalol | 1981 |
Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Male; Metoprolol; Propranolol; Sotalol; Vascular Resistance | 1981 |
A simple method to determine the ratio of cardiac to vascular beta-receptor blockade in the rat in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cardiovascular System; Female; Heart Rate; Isoproterenol; Pindolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Sotalol | 1981 |
[Intoxication by beta-blockers in children and adolescents (author's transl)].
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Child, Preschool; Female; Glucagon; Humans; Hypoglycemia; Propranolol; Shock; Sotalol; Suicide, Attempted | 1982 |
[Therapy of essential tremor with special reference to the use of beta-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bupranolol; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Pindolol; Prognosis; Propranolol; Sotalol; Tremor | 1982 |
Prolongation of the human cardiac monophasic action potential by sotalol.
Topics: Action Potentials; Adrenergic beta-Antagonists; Adult; Aged; Cardiac Catheterization; Double-Blind Method; Electrocardiography; Heart; Heart Conduction System; Humans; Middle Aged; Myocardial Contraction; Propranolol; Sotalol; Time Factors | 1982 |
Inotropic beta-blocking potency (pA2) and partial agonist activity of propranolol, practolol, sotalol and acebutolol.
Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Papillary Muscles; Practolol; Propranolol; Reserpine; Sotalol | 1982 |
Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Humans; Hyperthyroidism; Metoprolol; Middle Aged; Propranolol; Sotalol; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Antifibrillatory properties of the beta-adrenergic receptor antagonists, nadolol, sotalol, atenolol and propranolol, in the anesthetized dog.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atenolol; Dogs; Dose-Response Relationship, Drug; Heart Conduction System; Male; Nadolol; Propanolamines; Propranolol; Sotalol; Ventricular Fibrillation | 1984 |
Enhancement of physiological finger tremor by intravenous isoprenaline infusions in man: evaluation of its role in the assessment of beta-adrenoceptor antagonists.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Female; Fingers; Heart Rate; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Isoproterenol; Male; Practolol; Propranolol; Sotalol; Tremor | 1984 |
Class III action of beta-blocking agents.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Female; Heart; Heart Ventricles; Male; Nadolol; Oxprenolol; Pindolol; Propanolamines; Propranolol; Sotalol; Timolol | 1984 |
Effects of nipradilol (K-351) on the electrophysiological properties of canine cardiac tissues: comparison with propranolol and sotalol.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Dogs; Female; Heart; In Vitro Techniques; Male; Propanolamines; Propranolol; Purkinje Fibers; Refractory Period, Electrophysiological; Sotalol | 1984 |
Pharmacokinetics, central nervous system uptake, and lipid solubility of propranolol, acebutolol, and sotalol.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Brain; Buffers; Cats; Chromatography, High Pressure Liquid; Kinetics; Lipids; Male; Propranolol; Solubility; Sotalol | 1984 |
Antagonism of an indirectly acting agonist: block by propranolol and sotalol of the action of tyramine on rat heart.
Topics: Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Models, Theoretical; Myocardial Contraction; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic, beta; Sotalol; Tyramine | 1980 |
Interaction between parathyroid hormone and the beta-adrenoceptor system in cultured rat myocardial cells.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Isoproterenol; Myocardium; Parathyroid Hormone; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol | 1980 |
Pharmacological evidence that the sympathetic nervous system mediates the increase in secretion of renin produced by p-chloroamphetamine.
Topics: Amphetamines; Animals; Blood Pressure; Chlorisondamine; Isoproterenol; Male; p-Chloroamphetamine; Propranolol; Rats; Rats, Inbred Strains; Renin; Sotalol; Sympathetic Nervous System | 1984 |
Different toxicological profiles for various beta-blocking agents on cardiac function in isolated rat hearts.
Topics: Animals; Coronary Circulation; Depression, Chemical; Electric Stimulation; Heart Rate; Male; Myocardial Contraction; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Time Factors; Timolol | 1984 |
The treatment of nontoxic goitre with thyroxine and beta-blockers.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Goiter; Humans; Male; Middle Aged; Propranolol; Sotalol; Thyroxine | 1984 |
Comparison of sotalol and propranolol in mild to moderate essential hypertension.
Topics: Adult; Blood Pressure; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Propranolol; Sotalol; Time Factors | 1983 |
Effects of three bradycardiac drugs on regional myocardial blood flow and function in areas distal to a total or partial coronary occlusion in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Collateral Circulation; Coronary Circulation; Coronary Disease; Depression, Chemical; Dogs; Female; Heart Rate; Male; Metoprolol; Propranolol; Sotalol | 1984 |
Social drinking and drugs.
Topics: Alcohol Drinking; Drug Interactions; Ethanol; Humans; Propranolol; Sotalol | 1981 |
The B-aminopropionitrile-fed turkey: a model for detecting potential drug action on arterial tissue.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Disease Models, Animal; Hemodynamics; Hydralazine; Male; Phenelzine; Practolol; Propranolol; Reserpine; Sotalol; Tensile Strength; Turkeys | 1983 |
Central pre- and postsynaptic monoamine receptors in antidepressant therapy.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Catecholamines; Iontophoresis; Male; Metoprolol; Neurons; Propranolol; Rats; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Sotalol; Synapses | 1981 |
Propranolol and sotalol augment the coronary vasodilatory action of prostacyclin (PGI2) in rabbit isolated hearts.
Topics: Animals; Drug Synergism; Epoprostenol; Heart; Hypertension; In Vitro Techniques; Perfusion; Propranolol; Prostaglandins; Rabbits; Sotalol; Vasodilation | 1981 |
Transfer of propranolol and sotalol across the human placenta. Their effect on maternal and fetal plasma renin activity.
Topics: Adult; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Placenta; Pregnancy; Propranolol; Renin; Sotalol | 1982 |
Propranolol and sotalol metabolism after a drinking party.
Topics: Adult; Alcohol Drinking; Alcoholic Beverages; Blood Pressure; Female; Heart Rate; Humans; Liver; Male; Metabolic Clearance Rate; Propranolol; Sotalol | 1981 |
[Chronic administration of beta blocking agents: left ventricular hemodynamics in myocardial infarctions during exercise (author's transl)].
Topics: Adult; Angina Pectoris; Cardiac Catheterization; Electrocardiography; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Infarction; Physical Exertion; Propranolol; Sotalol | 1981 |
Comparison of the activity and plasma levels of oxprenolol, slow release oxprenolol, long acting propranolol and sotalol.
Topics: Adult; Delayed-Action Preparations; Female; Half-Life; Heart Rate; Humans; Male; Oxprenolol; Physical Exertion; Propranolol; Sotalol; Tachycardia; Time Factors | 1980 |
Alteration of the baroreceptor reflex by an effect of propranolol on the isolated carotid sinus.
Topics: Animals; Carotid Sinus; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; In Vitro Techniques; Male; Pressoreceptors; Procaine; Propranolol; Reflex; Sotalol | 1981 |
Positive and negative inotropic effects of DL-sotalol and D-sotalol in failing and nonfailing human myocardium under physiological experimental conditions.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Depression, Chemical; Dose-Response Relationship, Drug; Heart; Heart Failure; Heart Rate; Humans; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Propranolol; Sotalol; Stereoisomerism; Stimulation, Chemical | 1995 |
Injections of beta-noradrenergic substances in the cerebellar anterior vermis of cats affect adaptation of the vestibulospinal reflex gain.
Topics: Adaptation, Physiological; Animals; Cats; Cerebellum; Decerebrate State; Electromyography; Forelimb; Isoproterenol; Locus Coeruleus; Microinjections; Models, Neurological; Neck; Neuronal Plasticity; Norepinephrine; Posture; Propranolol; Proprioception; Purkinje Cells; Reflex; Rotation; Sotalol; Vestibular Nerve | 1994 |
K+ channel blockade in the prevention of ventricular fibrillation in dogs with acute ischemia and enhanced sympathetic activity.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dogs; Electrocardiography; Heart Rate; Myocardial Ischemia; Potassium Channel Blockers; Propranolol; Sotalol; Stereoisomerism; Sympathetic Nervous System; Ventricular Fibrillation | 1995 |
Relative toxicity of beta blockers in overdose.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child, Preschool; Databases, Factual; Drug Overdose; Female; Humans; Infant; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Prospective Studies; Seizures; Sotalol | 1996 |
Effects of acute cardioselective and non-selective beta-adrenergic blockade on plasma ammonia levels in exercising dogs.
Topics: Adrenergic beta-Antagonists; Ammonia; Animals; Anti-Arrhythmia Agents; Atenolol; Dogs; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Heart Rate; Infusions, Intravenous; Male; Physical Conditioning, Animal; Propranolol; Sotalol | 1996 |
Differential effect of selected antiarrhythmic drugs on coronary artery ligation-induced ventricular arrhythmias on the right or left sides.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Disease Models, Animal; Dogs; Female; Ligation; Male; Propranolol; Quinidine; Sotalol; Tachycardia, Ventricular; Verapamil | 1995 |
Experimental verification of the mechanistic model for transdermal transport including iontophoresis.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Biological Transport; Humans; Iontophoresis; Kinetics; Mathematical Computing; Models, Biological; Propranolol; Reproducibility of Results; Skin Absorption; Sotalol; Timolol | 1998 |
Liposome-skin interactions and their effects on the skin permeation of drugs.
Topics: Adrenergic beta-Antagonists; Chromatography, High Pressure Liquid; Diffusion; Drug Carriers; Energy Transfer; Fluoresceins; Fluorescent Dyes; Humans; In Vitro Techniques; Liposomes; Microscopy, Confocal; Pharmaceutical Preparations; Phospholipids; Propranolol; Skin Absorption; Sotalol | 1999 |
Sympathotropic drugs and the distribution of 99mTc-hydroxymethylene diphosphonate. Experimental studies in the mouse.
Topics: Adrenergic beta-Antagonists; Animals; Bone and Bones; Contrast Media; Ephedrine; Male; Metoprolol; Mice; Mice, Inbred Strains; Propranolol; Radionuclide Imaging; Sotalol; Sympathomimetics; Technetium Tc 99m Medronate; Terbutaline; Tissue Distribution | 1999 |
Drug release from a porous ion-exchange membrane in vitro.
Topics: Acrylic Resins; Adsorption; Atenolol; Biocompatible Materials; Cations; Dexmedetomidine; Diazepam; Drug Delivery Systems; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Membranes, Artificial; Polyvinyls; Propranolol; Sotalol; Surface Properties; Timolol | 1999 |
Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Chromans; Cnidarian Venoms; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; Heart Ventricles; Isoproterenol; Long QT Syndrome; Neurotoxins; Potassium Channel Blockers; Propranolol; Sotalol; Sulfonamides; Sympathetic Nervous System; Treatment Outcome | 2000 |
Arrhythmogenic activity of cardiac muscle in pulmonary veins of the dog: implication for the genesis of atrial fibrillation.
Topics: Acetylcholine; Action Potentials; Adenosine; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium Channel Blockers; Cardiac Pacing, Artificial; Dogs; Isoproterenol; Muscle, Smooth, Vascular; Myocardium; Potassium Channel Blockers; Propranolol; Pulmonary Veins; Sodium Channels; Sotalol; Tetrodotoxin | 2000 |
Oral amiodarone and atrial fibrillation.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Humans; Patient Selection; Propranolol; Sotalol; Tachycardia, Supraventricular; Treatment Outcome | 2001 |
Influence of age, the autonomic nervous system and anxiety on QT-interval variability.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Analysis of Variance; Anti-Arrhythmia Agents; Anxiety; Autonomic Nervous System; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Propranolol; Signal Processing, Computer-Assisted; Sotalol | 2001 |
Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Animals; Biological Transport; Chromatography, High Pressure Liquid; Drug Carriers; Injections, Intravenous; Iontophoresis; Irritants; Liposomes; Metoprolol; Oxprenolol; Propranolol; Rats; Skin; Skin Absorption; Sotalol; Stereoisomerism; Timolol | 2003 |
Chemoenzymatic synthesis of (S) and (R)-propranolol and sotalol employing one-pot lipase resolution protocol.
Topics: Lipase; Propranolol; Sotalol; Stereoisomerism | 2004 |
QT PRODACT: usability of miniature pigs in safety pharmacology studies: assessment for drug-induced QT interval prolongation.
Topics: Animals; Blood Pressure; Databases, Factual; Electrocardiography; Haloperidol; Heart Rate; Long QT Syndrome; Male; Models, Animal; Propranolol; Sotalol; Swine; Swine, Miniature; Telemetry | 2005 |
Cytochrome P450 (CYP) inhibition screening: comparison of three tests.
Topics: Citalopram; Cytochrome P-450 Enzyme Inhibitors; Diazepam; Enzyme Inhibitors; Fluoxetine; Humans; Oxazepam; Propranolol; Sotalol | 2006 |
QT-RR relationships and suitable QT correction formulas for halothane-anesthetized dogs.
Topics: Analysis of Variance; Anesthesia; Animals; Astemizole; Dogs; Electrocardiography; Halothane; Male; Propranolol; Sotalol | 2006 |
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil | 2007 |
Elimination of beta-blockers in sewage treatment plants.
Topics: Adrenergic beta-Antagonists; Adsorption; Atenolol; Chromatography, High Pressure Liquid; Kinetics; Metoprolol; Molecular Structure; Propranolol; Sotalol; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2007 |
Prediction of drug-induced QT interval prolongation in telemetered common marmosets.
Topics: Animals; Astemizole; Callithrix; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Heart Rate; Humans; Linear Models; Male; Nifedipine; Propranolol; Sotalol | 2008 |
Systemic propranolol acts centrally to reduce conditioned fear in rats without impairing extinction.
Topics: Action Potentials; Animals; Conditioning, Classical; Conditioning, Operant; Electroshock; Extinction, Psychological; Fear; Heart Rate; Injections, Intraperitoneal; Male; Motor Activity; Neurons; Prefrontal Cortex; Propranolol; Rats; Rats, Sprague-Dawley; Sotalol | 2009 |
Extraction and preconcentration of beta-blockers in human urine for analysis with high performance liquid chromatography by means of carrier-mediated liquid phase microextraction.
Topics: Adrenergic beta-1 Receptor Antagonists; Bisoprolol; Carteolol; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Propranolol; Reproducibility of Results; Sotalol | 2010 |
Intraosseous infusion is unreliable for adenosine delivery in the treatment of supraventricular tachycardia.
Topics: Adenosine; Amiodarone; Catheterization, Central Venous; Combined Modality Therapy; Drug Therapy, Combination; Emergencies; Humans; Infant; Infusions, Intraosseous; Infusions, Intravenous; Male; Procainamide; Propranolol; Recurrence; Sotalol; Tachycardia, Supraventricular; Treatment Failure; Vagus Nerve Stimulation | 2012 |
Pharmacophore modeling for hERG channel facilitation.
Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis | 2012 |
Fetal supraventricular tachycardia at 12 weeks of gestation: diagnosis and follow up. A case report.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Echocardiography; Female; Fetal Heart; Follow-Up Studies; Humans; Infant, Newborn; Male; Pregnancy; Propranolol; Sotalol; Tachycardia, Supraventricular; Ultrasonography, Prenatal; Young Adult | 2019 |
Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metal-Organic Frameworks; Metoprolol; Propanolamines; Propranolol; Sotalol; Stereoisomerism | 2019 |
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS.
Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil | 2019 |
Subcellular Propagation of Cardiomyocyte β-Adrenergic Activation of Calcium Uptake Involves Internal β-Receptors and AKAP7.
Topics: Adaptor Proteins, Signal Transducing; Adrenergic Agents; Animals; Calcium; Calcium Signaling; Calcium, Dietary; Isoproterenol; Myocytes, Cardiac; Propranolol; Rabbits; Receptors, Adrenergic, beta; Sotalol | 2022 |
Evaluating phospholipid- and protein-water partitioning of two groups of chemicals of emerging concern: Diastereo- and enantioselectivity.
Topics: Liposomes; Metoprolol; Molecular Docking Simulation; Phospholipids; Propranolol; Serum Albumin, Bovine; Sotalol; Water | 2022 |
Adsorption of Individual and Mixtures of β-Blockers and Copper in Soils and Sediments.
Topics: Adrenergic beta-Antagonists; Adsorption; Coordination Complexes; Copper; Pharmaceutical Preparations; Propranolol; Soil; Sotalol; Trace Elements; Water; Water Pollutants, Chemical | 2022 |
Adsorption and leaching of β-blockers in fluvo-aquic and black soil: Behavior characteristic and enantiomer selectivity.
Topics: Adsorption; Atenolol; Propranolol; Soil; Soil Pollutants; Sotalol | 2022 |