Page last updated: 2024-08-16

sotalol and prazosin

sotalol has been researched along with prazosin in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199012 (38.71)18.7374
1990's2 (6.45)18.2507
2000's8 (25.81)29.6817
2010's9 (29.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Harron, DW1
Giesen-Crouse, E; Imbs, JL; Schmidt, M1
Kasuya, Y; Nakazawa, K; Shigenobu, K1
Aloyo, VJ; Walker, RF1
Campeau, N; De Champlain, J; Godin, D; Lamontagne, D; Nadeau, R; Yamaguchi, N1
Ohno, Y; Sasa, M; Takaori, S; Yoshida, O; Yoshimura, N1
Jounela, AJ; Juustila, H; Lilja, M; Mattila, MJ1
Cocco, F; Dessì Fulgheri, P; Dettori, S; Fiori, C; Glorioso, N; Madeddu, P; Rappelli, A; Sanna, G1
Burvenich, C; Peeters, G; Vandeputte-Van Messom, G1
Downie, JW; Slack, BE1
Aärynen, M; Hämeenaho, P; Mäkelä, M; Mattila, MJ1
Sundin, LI1
Alper, RH; Zink, MH1
Axelsson, M; Conlon, JM; Jensen, J; Wang, T1
Canario, AV; Dinis, MT; Power, DM; Rotllant, J; Ruane, NM1
Bícego, KC; Gargaglioni, LH; Zena, LA1

Reviews

1 review(s) available for sotalol and prazosin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for sotalol and prazosin

ArticleYear
Interaction of clonidine and beta-blockers.
    Acta medica Scandinavica, 1980, Volume: 207, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol

1980
Prazosin enhances the antihypertensive effects of beta-blockers during isometric and dynamic exercise.
    Annals of clinical research, 1981, Volume: 13, Issue:2

    Topics: Adult; Atenolol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Prazosin; Propanolamines; Quinazolines; Sotalol

1981

Other Studies

28 other study(ies) available for sotalol and prazosin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Experimental evidence for the antiarrhythmic action of indoramin.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Coronary Vessels; Electrocardiography; Guinea Pigs; Heart; Heart Rate; Indoles; Indoramin; Mexiletine; Myocardial Contraction; Prazosin; Rats; Sotalol

1986
Renal and iliac vascular effects of dopamine in the anaesthetized rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:4

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Butaclamol; Dopamine; Drug Interactions; Iliac Artery; Indomethacin; Male; Methiothepin; Prazosin; Rats; Regional Blood Flow; Renal Circulation; Reserpine; Sotalol; Vascular Resistance; Yohimbine

1987
Are alpha-adrenoceptors involved in positive inotropic effects of phenylephrine in chick ventricles?
    Japanese journal of pharmacology, 1987, Volume: 45, Issue:1

    Topics: Animals; Calcium; Chick Embryo; Chickens; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Myocardium; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sotalol; Stimulation, Chemical

1987
Molecular mechanisms controlling norepinephrine-mediated release of serotonin from rat pineal glands.
    Advances in experimental medicine and biology, 1987, Volume: 221

    Topics: Animals; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Serotonin; Sotalol; Tetradecanoylphorbol Acetate

1987
Effects of sotalol, (-)-propranolol and prazosin on reperfusion-induced arrhythmias and increased cardiac norepinephrine release.
    European journal of pharmacology, 1986, Apr-09, Volume: 123, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Catecholamines; Coronary Circulation; Creatine Kinase; Dogs; Female; Heart; Hemodynamics; Isoproterenol; Lactates; Male; Myocardium; Norepinephrine; Prazosin; Propranolol; Sotalol

1986
Contraction of urinary bladder by central norepinephrine originating in the locus coeruleus.
    The Journal of urology, 1988, Volume: 139, Issue:2

    Topics: Animals; Cats; Electric Stimulation; Hypogastric Plexus; Levodopa; Locus Coeruleus; Muscle Contraction; Norepinephrine; Phentolamine; Prazosin; Pressure; Reserpine; Sotalol; Urinary Bladder; Yohimbine

1988
[Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension (author's transl)].
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Metoprolol; Middle Aged; Prazosin; Renin; Sotalol; Spironolactone

1981
Action of epinephrine on the function of the teat sphincter in the lactating cow.
    American journal of veterinary research, 1984, Volume: 45, Issue:10

    Topics: Animals; Cattle; Drug Interactions; Epinephrine; Female; Injections, Intra-Arterial; Lactation; Mammary Glands, Animal; Milk Ejection; Muscle Contraction; Muscle, Smooth; Prazosin; Pregnancy; Sotalol

1984
Pharmacological analysis of the responses of the feline urethra to autonomic nerve stimulation.
    Journal of the autonomic nervous system, 1983, Volume: 8, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Cats; Hexamethonium Compounds; Hypogastric Plexus; Male; Muscle, Smooth; Parasympathetic Nervous System; Prazosin; Sotalol; Sympathetic Nervous System; Urethra

1983
Responses of the branchial circulation to hypoxia in the Atlantic cod, Gadus morhua.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Animals; Blood Circulation; Blood Pressure; Cardiac Output; Epinephrine; Female; Fishes; Gills; Hypoxia; Male; Methysergide; Models, Biological; Prazosin; Receptors, Adrenergic, beta; Serotonin; Sotalol; Vascular Resistance; Vasoconstriction

1995
Adrenergic and nonadrenergic regulation of hindlimb blood flow during stress in rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Animals; Blood Pressure; Epinephrine; Heart Rate; Hemodynamics; Hindlimb; Ilium; Male; Muscles; Neurotransmitter Agents; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Regional Blood Flow; Sotalol; Stress, Physiological; Vascular Resistance; Vasodilation

1994
Cardiovascular actions of python bradykinin and substance P in the anesthetized python, Python regius.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alligators and Crocodiles; Animals; Boidae; Bradykinin; Cardiovascular System; Epinephrine; Female; Male; Norepinephrine; Prazosin; Sotalol; Substance P; Turtles

2000
Intra-adrenal interactions in fish: catecholamine stimulated cortisol release in sea bass (Dicentrarchus labrax L.).
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2006, Volume: 143, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bass; Epinephrine; Hydrocortisone; Inositol; Interrenal Gland; Norepinephrine; Prazosin; Second Messenger Systems; Sotalol

2006
Role of brain nitric oxide in the cardiovascular control of bullfrogs.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2013, Volume: 165, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Body Temperature; Brain; Enzyme Inhibitors; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Nitric Oxide; omega-N-Methylarginine; Prazosin; Rana catesbeiana; Skin; Sotalol

2013