Page last updated: 2024-08-16

sotalol and phenoxybenzamine

sotalol has been researched along with phenoxybenzamine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199030 (83.33)18.7374
1990's2 (5.56)18.2507
2000's1 (2.78)29.6817
2010's3 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Green, K; Kim, K1
Clements, JA; Oyarzun, MJ1
Edström, A; Kanje, M; Löfgren, P; Walum, E1
Daly, JW; Skolnick, P1
de Champlain, J; Nadeau, RA; Yamaguchi, N1
Bigger, JF; Bowman, K; Green, K; Kim, K1
Cooling, MJ; Day, MD1
Dhawan, BN; Kumar, A; Raghubir, R2
Giesen-Crouse, EM; Imbs, JL; Krieger, JP; Schmidt, M1
Aou, S; Lénárd, L; Nishino, H; Oomura, Y1
Goldberg, LI; Toda, N1
Daly, JW; Schultz, J1
Hodgins, DS; Kuo, JF; Kuo, WN1
Abel, P; Buckner, CK1
Janis, RA; Triggle, DJ1
Emerson, TE1
Greengard, P; Kalix, P; McAfee, DA; Schorderet, M1
Canessa de Scarnati, O; Lapetina, EG1
Bourne, RK; Davis, WG1
Anton, AH; Goldberg, LI; Tjandramaga, TB; Toda, N1
Awad, SA; Bruce, AW; Carro-Ciampi, G; Downie, JW; Lin, M; Marks, GS1
Baile, CA; Krabill, LF; Martin, FH; Simpson, CW1
Lockwood, RH; Lum, BK1
Ohkawa, H; Prosser, CL1
Bose, D; Innes, IR1
Green, KL1
Cleophas, TJ; Faaber, P; Fennis, JF; van Lier, HJ; van't Laar, A1
Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S1
Kandasamy, SB; Williams, BA1
Elijah, D; Green, K1

Reviews

1 review(s) available for sotalol and phenoxybenzamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for sotalol and phenoxybenzamine

ArticleYear
Therapeutic efficacy of alpha-adrenoceptor blockade in primary and secondary Raynaud's syndrome.
    Angiology, 1984, Volume: 35, Issue:11

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Autoimmune Diseases; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Phenoxybenzamine; Random Allocation; Raynaud Disease; Sotalol

1984

Other Studies

34 other study(ies) available for sotalol and phenoxybenzamine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye.
    Investigative ophthalmology, 1976, Volume: 15, Issue:2

    Topics: 1-Propanol; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cannabis; Dronabinol; Drug Interactions; Eye; Intraocular Pressure; Phenoxybenzamine; Phentolamine; Prostaglandins; Rabbits; Sotalol

1976
Control of lung surfactant by ventilation, adrenergic mediators, and prostaglandins in the rabbit.
    The American review of respiratory disease, 1978, Volume: 117, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Indomethacin; Isoproterenol; Male; Meclofenamic Acid; Phenoxybenzamine; Phosphatidylcholines; Propranolol; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins H; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits; Respiration; Sotalol; Terbutaline

1978
Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells.
    Experimental cell research, 1975, Oct-15, Volume: 95, Issue:2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Catecholamines; Cell Line; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Epinephrine; Glioma; Isoproterenol; Neurons; Papaverine; Phenoxybenzamine; Prostaglandins E; Sotalol; Zeatin

1975
Interaction of clonidine with pre- and post-synaptic adrenergic receptors of rat brain: effects on cyclic AMP-generating systems.
    European journal of pharmacology, 1976, Volume: 39, Issue:1

    Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Clonidine; Cyclic AMP; Drug Interactions; Drug Synergism; Hydroxydopamines; Isoproterenol; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred F344; Sotalol

1976
Regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors.
    Circulation research, 1977, Volume: 41, Issue:1

    Topics: Adrenergic Fibers; Animals; Catecholamines; Clonidine; Desipramine; Dogs; Electric Stimulation; Heart; Hemodynamics; Isoproterenol; Norepinephrine; Phenoxybenzamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sotalol

1977
Cannabinoid action on the eye as mediated through the central nervous system and local adrenergic activity.
    Experimental eye research, 1977, Volume: 24, Issue:2

    Topics: Animals; Brain; Cannabinoids; Dronabinol; Eye; Ganglia, Autonomic; Intraocular Pressure; Phenoxybenzamine; Rabbits; Sotalol

1977
Drinking behaviour in the cat induced by renin, angiotensin I, II and isoprenaline.
    The Journal of physiology, 1975, Volume: 244, Issue:2

    Topics: Angiotensin II; Animals; Atropine; Bethanidine; Cats; Cerebral Ventricles; Drinking Behavior; Hexamethonium Compounds; Infusions, Parenteral; Isoproterenol; Pempidine; Phenoxybenzamine; Phentolamine; Practolol; Propranolol; Renin; Sotalol; Stimulation, Chemical; Tolazoline

1975
Involvement of adrenergic & cholinergic mechanisms in analgesia electrically induced from pretectal nucleus of rat.
    The Indian journal of medical research, 1991, Volume: 94

    Topics: Analgesia; Animals; Atropine; Electric Stimulation; Haloperidol; Male; Neurotransmitter Agents; Phenoxybenzamine; Rats; Sotalol; Tail; Tectum Mesencephali

1991
Effect of monoamine antagonists on pretectal evoked analgesia in rat.
    Indian journal of experimental biology, 1991, Volume: 29, Issue:1

    Topics: Analgesia; Animals; Biogenic Monoamines; Electric Stimulation; Haloperidol; Ketanserin; Methysergide; Phenoxybenzamine; Rats; Serotonin Antagonists; Sotalol

1991
Vascular effects of selective dopamine receptor agonists and antagonists in the rat kidney.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 286, Issue:2

    Topics: Animals; Benzazepines; Dopamine Antagonists; Ergolines; Male; Phenoxybenzamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Renal Circulation; Sotalol; Sulpiride

1987
Catecholaminergic mechanisms of feeding-related lateral hypothalamic activity in the monkey.
    Brain research, 1987, Mar-03, Volume: 405, Issue:1

    Topics: Animals; Brain Mapping; Conditioning, Operant; Dopamine; Feeding Behavior; Hypothalamic Area, Lateral; Macaca mulatta; Norepinephrine; Phenoxybenzamine; Sotalol

1987
Dopamine-induced relaxation of isolated arterial strips.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:7

    Topics: Animals; Dogs; Dopamine; Femoral Artery; Guinea Pigs; Haplorhini; In Vitro Techniques; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Norepinephrine; Papaverine; Phenoxybenzamine; Rabbits; Receptors, Drug; Renal Artery; Sotalol

1973
Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effects of alpha- and beta-adrenergic agents, histamine, serotonin and adenosine.
    Journal of neurochemistry, 1973, Volume: 21, Issue:3

    Topics: Adenosine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Cyclic AMP; Diphenhydramine; Epinephrine; Ergotamine; Guinea Pigs; Histamine; In Vitro Techniques; Isomerism; Male; Methysergide; Norepinephrine; Pheniramine; Phenoxybenzamine; Phentolamine; Propranolol; Serotonin; Sotalol; Xanthines

1973
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
    Biochemical pharmacology, 1974, May-01, Volume: 23, Issue:9

    Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium

1974
Studies on the effects of enantiomers of soterenol, trimetoquinol and salbutamol on beta adrenergic receptors of isolated guinea-pig atria and trachea.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Anilides; Animals; Benzyl Compounds; Dose-Response Relationship, Drug; Ethanolamines; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Isomerism; Isoproterenol; Isoquinolines; Muscle Contraction; Phenethylamines; Phenoxybenzamine; Phentolamine; Receptors, Adrenergic; Sotalol; Sulfonamides; Trachea

1974
On the reversal by (plus) and (minus)-propranolol of irreversible alpha-adrenoceptor blockade in rabbit aorta.
    Pharmacological research communications, 1974, Volume: 6, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding Sites; Bromine; Carboxylic Acids; Dimethylamines; Ethyl Ethers; In Vitro Techniques; Isomerism; Isoquinolines; Methylamines; Muscle Contraction; Mustard Compounds; Naphthalenes; Norepinephrine; Phenethylamines; Phenoxybenzamine; Propranolol; Rabbits; Sotalol

1974
Changes of venous return and other hemodynamic parameters during bradykinin infusion.
    The American journal of physiology, 1967, Volume: 212, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Body Weight; Bradykinin; Cardiac Output; Coronary Circulation; Dogs; Female; Heart Rate; Hematocrit; Hemodynamics; Hydrogen-Ion Concentration; Injections, Intravenous; Male; Phenoxybenzamine; Sotalol

1967
Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:3

    Topics: Adenosine; Animals; Atropine; Benzyl Compounds; Bethanechol Compounds; Calcium; Carbachol; Cyclic AMP; Electric Stimulation; Ethers; Ganglia, Spinal; Hexamethonium Compounds; Imidazoles; In Vitro Techniques; Moxisylyte; Parasympatholytics; Phenoxybenzamine; Phentolamine; Phosphodiesterase Inhibitors; Rabbits; Sotalol; Sympatholytics; Synapses; Theophylline; Time Factors

1974
Adrenergic stimulation of phosphatidylinositol labelling in rat vas deferens.
    Biochimica et biophysica acta, 1974, Sep-19, Volume: 360, Issue:3

    Topics: Animals; Chromatography, Thin Layer; Isoproterenol; Kinetics; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphorus Radioisotopes; Rats; Receptors, Adrenergic; Sotalol; Time Factors; Vas Deferens

1974
The effects of corticosteroids on the reduction of -adrenoceptor blockade produced by -adrenoceptor blocking agents.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Blood Pressure; Cortisone; Desoxycorticosterone; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Sotalol; Sympatholytics

1972
Continuing studies of the peripheral vascular actions of dopamine.
    Advances in neurology, 1974, Volume: 5

    Topics: Animals; Barium; Basilar Artery; Constriction; Coronary Vessels; Dilatation; Dogs; Dopamine; Femoral Artery; Heart; Levodopa; Mesenteric Arteries; Phenoxybenzamine; Propranolol; Prostaglandin Antagonists; Receptors, Drug; Renal Artery; Sotalol; Structure-Activity Relationship; Vasodilator Agents; Vasopressins

1974
Distribution of alpha- and beta-adrenoceptors in human urinary bladder.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: Acetylcholine; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phenylephrine; Propranolol; Receptors, Adrenergic; Sotalol; Sympathomimetics; Urinary Bladder

1974
Adrenergic agonists and antagonists and feeding in sheep and cattle.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jul-15, Volume: 11, Issue:14

    Topics: Animals; Cattle; Cerebral Ventricles; Dose-Response Relationship, Drug; Feeding Behavior; Hypothalamus; Isoproterenol; Norepinephrine; Phenoxybenzamine; Propranolol; Sheep; Sotalol; Stereoisomerism; Stereotaxic Techniques; Structure-Activity Relationship

1972
Effects of adrenergic agonists and antagonists on potassium metabolism.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:1

    Topics: Albuterol; Animals; Blood Glucose; Blood Pressure; Butoxamine; Cats; Epinephrine; Ethanolamines; Heart Rate; Hyperkalemia; Isoproterenol; Norepinephrine; Pancreas; Phenethylamines; Phenoxybenzamine; Phenylephrine; Potassium; Potassium Chloride; Practolol; Propanolamines; Propranolol; Propylamines; Sotalol; Sulfonamides; Sympatholytics; Sympathomimetics; Thiazoles; Time Factors; Toluene

1974
Functions of neurons in enteric plexuses of cat intestine.
    The American journal of physiology, 1972, Volume: 222, Issue:6

    Topics: Acetylcholine; Animals; Atropine; Cats; Electrophysiology; Epinephrine; Hexamethonium Compounds; In Vitro Techniques; Intestine, Small; Lidocaine; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; Nicotine; Norepinephrine; Phenoxybenzamine; Serotonin; Sotalol; Submucous Plexus; Tetrodotoxin; Tubocurarine

1972
Isoprenaline-induced relaxation of smooth muscle not due to electrogenic sodium pumping.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:4

    Topics: Animals; Biological Transport; Carotid Arteries; Cats; Cell Membrane Permeability; Depression, Chemical; Female; In Vitro Techniques; Isoproterenol; Lithium; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Phenoxybenzamine; Potassium Chloride; Receptors, Adrenergic; Sodium; Sotalol; Stimulation, Chemical

1972
The anti-inflammatory effect of catecholamines in the peritoneal cavity and hind paw of the mouse.
    British journal of pharmacology, 1972, Volume: 45, Issue:2

    Topics: Adrenalectomy; Amino Alcohols; Animals; Anti-Inflammatory Agents; Blood Glucose; Bradykinin; Capillary Permeability; Catecholamines; Dihydroxyphenylalanine; Dopamine; Edema; Epinephrine; Hindlimb; Histamine; Hydrocortisone; Insulin; Isoproterenol; Mice; Nitrobenzenes; Norepinephrine; Peritoneal Cavity; Phenoxybenzamine; Propranolol; Sotalol; Sympatholytics

1972
Effects of electroconvulsive shock on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:2

    Topics: Aggression; Animals; Behavior, Animal; Electroconvulsive Therapy; Electroencephalography; Emotions; Humans; Male; Motor Activity; Norepinephrine; Olfactory Bulb; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sotalol

1981
Central effects of dibutyryl cyclic AMP and GMP on the temperature in conscious rabbits.
    Brain research, 1983, Oct-31, Volume: 277, Issue:2

    Topics: Animals; Anisomycin; Atropine; Body Temperature Regulation; Brain; Bucladesine; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Indomethacin; Injections, Intraventricular; Male; Naloxone; Phenoxybenzamine; Phosphodiesterase Inhibitors; Prostaglandins E; Rabbits; Receptors, Neurotransmitter; Sotalol; Tubocurarine

1983
Drug effects on aqueous humor formation and pseudofacility in normal rabbit eyes.
    Experimental eye research, 1981, Volume: 33, Issue:3

    Topics: Animals; Aqueous Humor; Atropine; Bradykinin; Dexamethasone; Dopamine; Intraocular Pressure; Melanocyte-Stimulating Hormones; Ouabain; Phenoxybenzamine; Prednisolone; Rabbits; Sotalol; Timolol

1981