Page last updated: 2024-08-16

sotalol and metoprolol

sotalol has been researched along with metoprolol in 103 studies

Research

Studies (103)

Timeframe	Studies, this research(%)	All Research%
pre-1990	45 (43.69)	18.7374
1990's	14 (13.59)	18.2507
2000's	22 (21.36)	29.6817
2010's	18 (17.48)	24.3611
2020's	4 (3.88)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Baker, JG	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J	1
Levy, JV	1
Meier, J	1
Kiechel, JR; Meier, J	1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S	1
Kittel, E; Philippu, A	1
Anderson, R	1
Allavena, A; Brambilla, G; Gazzaniga, GM; Martelli, A; Mazzei, M; Robbiano, L	1
Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR	1
Beudin, P; Ducher, JL; Gibert, J; Kantelip, JP; Lauxerois, M; Pechadre, JC; Sabot, C; Trolese, JF	1
Carrageta, MO; Raftery, EB	1
Fink, M; Lemmer, B; Ohm, T; Winkler, H	1
Timmermans, PB; van Zwieten, PA	1
Brownlee, WC; Durrington, PN; Large, DM	1
Arendt, RM; Greenblatt, DJ; Mutschler, E; Ochs, HR; Schäfer-Korting, M	1
Fishbein, L; Jackson, CD	1
Brunninkhuis, L; Harink, J; Janssen, J; Kootstra, G; Loomans, L; Taams, M; van der Starre, P	1
Alexopoulos, D; Cobbe, SM; Manley, BS; Robinson, GJ	1
Hallberg, H	1
Komar, K; Tarnow, J	1
Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M	1
Blomström-Lundqvist, C; Dohnal, M; Edvardsson, N; Hirsch, I; Hjalmarson, A; Lindblad, A; Olsson, SB	1
Gülker, H; Haverkamp, W; Hindricks, G; Thale, J	1
Gao, TL; Rizos, I; Senges, J	1
Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C	1
Giorgetti, F; Re, L; Rossini, L	1
Jefferson, D; Leigh, PN; Marsden, CD; Twomey, A	2
Alkondon, M; Bhatia, S; Sen, P; Sivam, SP	1
Buck, JD; Gross, GJ; Hardman, HF; Warltier, DC	1
Lessem, J	1
Cocco, F; Dessì Fulgheri, P; Dettori, S; Fiori, C; Glorioso, N; Madeddu, P; Rappelli, A; Sanna, G	1
Gerstenbrand, F; Klingler, D; Poewe, W	1
Amery, A; Bulpitt, C; Cattaert, A; Fagard, R; Staessen, J; Vanhees, L	1
Christensen, LK; Hansen, JM; Perrild, H; Skovsted, L	1
Weisswange, A	1
Friedewald, WT; Frishman, WH; Furberg, CD	1
Tomov, I	1
Anderson, R; Grabow, G	1
Brachmann, J; Cobbe, SM; Hoffman, E; Kübler, W; Ritzenhoff, A; Senges, J	1
Gross, GJ; Hardman, HF; Lamping, KG; Warltier, DC	1
Brachmann, J; Czygan, E; Jauernig, R; Kübler, W; Lengfelder, W; Rizos, I; Senges, J	1
Dahlöf, C; Engberg, G; Hallberg, H; Svensson, TH	1
Andersson, O; Berglund, G; Descamps, R; Thomis, J	1
Balnave, K; Harron, DW; Kinney, CD; Russell, CJ; Shanks, RG; Wilson, R	1
Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C	1
De Clerck, F; Lu, HR; Remeysen, P	1
Raza, A	1
Horowitz, JD; Ritchie, RH; Zhang, YI	1
Antz, M; Cappato, R; Kuck, KH	1
Buckley, NA; Dawson, AH; Epid, D; Reith, DM; Sayer, GP; Whyte, IM	1
Dorian, P; Greene, M; Nanthakumar, K; Newman, D; Paquette, M; Rakovich, G	1
Heikkilä, L; Järvinen, A; Parikka, H; Toivonen, L; Virtanen, K	1
Horowitz, JD; Morgan, DJ; Ritchie, RH	1
Hauer, B; Schwick, NG; Seidl, K; Senges, J; Zahn, R	1
Cronhjort, M; Jacobsson, H; Jonsson, C	1
O'Brien, E; Owens, P	1
Aurier, E; Bartoletti, A; Caponi, D; Carboni, A; Contini, S; Favaro, L; Finardi, A; Gherli, T; Lepera, G; Maranga, SS; Naccarella, F; Rolli, A	1
Igoumenidis, NE; Kalebubas, MD; Kanoupakis, EM; Kochiadakis, GE; Mavrakis, HE; Vardakis, KE; Vardas, PE	1
Grönefeld, G; Hohnloser, SH; Klingenheben, T; Li, YG	1
Bosch, RF; Dörnberger, V; Kettering, K; Kühlkamp, V; Mewis, C; Vonthein, R	1
Banga, AK; Betageri, GV; Chaturvedula, A; Conjeevaram, R; Sunkara, G	1
Auer, J; Berent, R; Eber, B; Hartl, P; Lamm, G; Lassnig, E; Lehner, E; Ng, CK; Puschmann, R; Schwarz, C; Strasser, U; Weber, T	1
Binder, WD; Fifer, MA; King, ME; Stone, JR	1
Champagne, J; Connolly, SJ; Dorian, P; Fain, E; Gent, M; Hohnloser, SH; Israel, CW; Roberts, R	1
Hii, JT; Horowitz, JD; Ritchie, RH; Wuttke, RD; Zeitz, CJ	1
Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C	1
Alder, AC; Escher, BI; Maurer, M; Richle, P; Schaffner, C	1
Abildstrøm, SZ; Andersen, SS; Folke, F; Fosbøl, E; Gislason, GH; Hansen, ML; Køber, L; Madsen, M; Rasmussen, S; Schramm, TK; Sørensen, R; Torp-Pedersen, C	1
Baranowska, I; Wilczek, A	1
Strickberger, SA; Venkataraman, G	1
Amidon, GL; Dahan, A; Hilfinger, JM; Lennernäs, H; Miller, JM; Yamashita, S; Yu, LX	1
Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y	1
Hariman, RJ; Khin, MM; Zoble, RG	1
Ge, H; Jiang, H; Li, X; Liu, H	1
Ermakov, S; Gerstenfeld, EP; Scheinman, MM; Svetlichnaya, Y	1
Chen, C; Ding, W; Du, Y; Ma, X; Sun, X; Tao, Y	1
Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B	1
Chen, L; Cui, F; Gao, L; Lu, J; Meng, W; Xin, Y; Xu, L	1
He, Y; Lu, Y; Ruan, Y; Sun, H; Xu, J; Zhang, Y; Zhu, H	1
Ballotari, M; Gottardo, R; Tagliaro, F; Taus, F; Utzeri, C	1

Reviews

7 review(s) available for sotalol and metoprolol

Article	Year
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:11 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship	1988
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Comparative pharmacokinetics of beta-blockers]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol	1978
Hypertension and beta-blockers. Are they all the same? International journal of cardiology, 1985, Volume: 7, Issue:4 Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Labetalol; Metoprolol; Pindolol; Receptors, Adrenergic, alpha; Sotalol	1985
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct]. Vutreshni bolesti, 1984, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol	1984

Trials

24 trial(s) available for sotalol and metoprolol

Article	Year
[Central effects of five beta-adrenergic receptor blockers in healthy volunteers: a quantitative EEG study]. Neurophysiologie clinique = Clinical neurophysiology, 1989, Volume: 19, Issue:1 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Brain; Carteolol; Electroencephalography; Humans; Male; Metoprolol; Monitoring, Physiologic; Pindolol; Sotalol	1989
Short-term effects of beta-adrenoceptor blocking drugs with and without cardioselectivity and intrinsic sympathomimetic activity on lipoprotein metabolism in hypertriglyceridaemic patients and in normal men. Clinical science (London, England : 1979), 1985, Volume: 69, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Cholesterol; Cholesterol, HDL; Female; Half-Life; Heart Rate; Humans; Hyperlipoproteinemias; Lipoproteins; Lipoproteins, VLDL; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Sotalol; Triglycerides	1985
Prevention and treatment of supraventricular tachycardia shortly after coronary artery bypass grafting: a randomized open trial. Angiology, 1986, Volume: 37, Issue:8 Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Coronary Artery Bypass; Humans; Metoprolol; Random Allocation; Sotalol; Stroke Volume; Tachycardia	1986
Effect of long term treatment with metoprolol and sotalol on ventricular repolarisation measured by use of transoesophageal atrial pacing. British heart journal, 1986, Volume: 55, Issue:2 Topics: Aged; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Clinical Trials as Topic; Computers; Double-Blind Method; Electrocardiography; Heart Rate; Heart Ventricles; Humans; Long-Term Care; Male; Metoprolol; Middle Aged; Sotalol	1986
Duration of action of beta blockers. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol	1980
beta-Adrenoceptor antagonists and essential tremor. Lancet (London, England), 1981, May-16, Volume: 1, Issue:8229 Topics: Adult; Aged; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Random Allocation; Sotalol; Tremor	1981
Beta-blocker therapy evaluated by radionuclide angiography: a study in chronic stable angina. Clinical cardiology, 1982, Volume: 5, Issue:6 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Cardiac Volume; Chronic Disease; Echocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propranolol; Radionuclide Imaging; Sotalol; Stroke Volume	1982
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients. American heart journal, 1982, Volume: 104, Issue:6 Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Oxprenolol; Practolol; Propranolol; Recurrence; Sotalol; Timolol	1982
[Improved prognosis using beta blockers after myocardial infarct?]. Lebensversicherungs Medizin, 1984, Jan-01, Volume: 36, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Prognosis; Propranolol; Sotalol; Timolol	1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct]. Vutreshni bolesti, 1984, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol	1984
Beta-adrenoreceptor mechanisms in essential tremor; a double-blind placebo controlled trial of metoprolol, sotalol and atenolol. Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:8 Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Pulse; Receptors, Adrenergic, beta; Sotalol; Tremor	1983
Sotalol and metoprolol comparison of their anti-hypertensive effect. European journal of clinical pharmacology, 1981, Volume: 21, Issue:2 Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Sotalol	1981
Effects on exercise tachycardia during forty-eight hours of a series of doses of atenolol, sotalol, and metoprolol. Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:3 Topics: Adolescent; Adult; Atenolol; Dose-Response Relationship, Drug; Half-Life; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Propanolamines; Sotalol; Time Factors	1981
Postextrasystolic potentiation in patients with ischaemic heart disease: influence of inotropic agents. British journal of clinical pharmacology, 1995, Volume: 40, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiac Complexes, Premature; Cardiotonic Agents; Female; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Milrinone; Myocardial Contraction; Myocardial Ischemia; Myocardial Stunning; Phosphodiesterase Inhibitors; Pyridones; Sotalol; Ventricular Function, Left	1995
Metoprolol versus sotalol in the treatment of sustained ventricular tachycardia. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4 Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Angiography; Double-Blind Method; Echocardiography; Electric Stimulation; Electrocardiography; Electrophysiology; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Sotalol; Tachycardia, Ventricular; Treatment Outcome	1995
Comparison of sotalol and metoprolol in the prevention of atrial fibrillation after coronary artery bypass surgery. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Electrocardiography; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Single-Blind Method; Sotalol	1998
Myocardial effect compartment modeling of metoprolol and sotalol: importance of myocardial subsite drug concentration. Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:2 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Area Under Curve; Depression, Chemical; Heart Rate; Humans; Injections, Intravenous; Linear Models; Metoprolol; Models, Biological; Myocardial Contraction; Myocardium; Regression Analysis; Sotalol	1998
Comparison of metoprolol and sotalol in preventing ventricular tachyarrhythmias after the implantation of a cardioverter/defibrillator. The American journal of cardiology, 1998, Sep-15, Volume: 82, Issue:6 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Defibrillators, Implantable; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Secondary Prevention; Sotalol; Survival Rate; Tachycardia, Ventricular; Treatment Outcome	1998
Sotalol vs metoprolol for ventricular rate control in patients with chronic atrial fibrillation who have undergone digitalization: a single-blinded crossover study. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2001, Volume: 3, Issue:1 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Circadian Rhythm; Cross-Over Studies; Digoxin; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Single-Blind Method; Sotalol	2001
Effect of metoprolol and d,l-sotalol on microvolt-level T-wave alternans. Results of a prospective, double-blind, randomized study. Journal of the American College of Cardiology, 2001, Volume: 38, Issue:7 Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Cause of Death; Coronary Disease; Death, Sudden, Cardiac; Double-Blind Method; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Sotalol; Survival Rate; Tachycardia, Ventricular	2001
Efficacy of metoprolol and sotalol in the prevention of recurrences of sustained ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator. Pacing and clinical electrophysiology : PACE, 2002, Volume: 25, Issue:11 Topics: Defibrillators, Implantable; Female; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Recurrence; Sotalol; Tachycardia, Ventricular	2002
A comparison between oral antiarrhythmic drugs in the prevention of atrial fibrillation after cardiac surgery: the pilot study of prevention of postoperative atrial fibrillation (SPPAF), a randomized, placebo-controlled trial. American heart journal, 2004, Volume: 147, Issue:4 Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Metoprolol; Middle Aged; Pilot Projects; Postoperative Complications; Premedication; Sotalol	2004
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial. Circulation, 2006, Jul-11, Volume: 114, Issue:2 Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Carbazoles; Carvedilol; Combined Modality Therapy; Defibrillators, Implantable; Female; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Sotalol; Ventricular Fibrillation; Ventricular Function, Left	2006

Other Studies

74 other study(ies) available for sotalol and metoprolol

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents. Bioorganic & medicinal chemistry, 2020, 05-01, Volume: 28, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured	2020
Beta-adrenergic receptor blocking drugs in spontaneous hypertension. The American journal of medicine, 1976, Volume: 61, Issue:5 Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors	1976
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents. Acta medica Scandinavica. Supplementum, 1977, Volume: 606 Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol	1977
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol	1979
Presence of beta-adrenoreceptors in the hypothalamus; their importance for the pressor response to hypothalamic stimulation. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:3 Topics: Animals; Blood Pressure; Catheterization; Cats; Drug Interactions; Electric Stimulation; Female; Hypothalamus; Isoproterenol; Male; Metoprolol; Practolol; Procaine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol; Stereoisomerism; Tolazoline	1977
Stimulation of normal and abnormal neutrophil motility in vitro by dexpropranolol, metoprolol and sotalol. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Aug-04, Volume: 56, Issue:5 Topics: Adult; Cell Movement; Chemotaxis, Leukocyte; Female; Humans; In Vitro Techniques; Male; Metoprolol; Neutrophils; Propanolamines; Propranolol; Sotalol	1979
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes. Cancer research, 1991, May-01, Volume: 51, Issue:9 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cell Survival; DNA; DNA Damage; DNA Repair; Humans; Liver; Male; Metoprolol; Nadolol; Nitrosamines; Nitrosation; Oxprenolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Nitrite; Sotalol	1991
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors. European heart journal, 1989, Volume: 10 Suppl B Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure; Humans; Infant; Isoproterenol; Metoprolol; Mitral Valve Stenosis; Myocardium; Propranolol; Receptors, Adrenergic, beta; Sotalol; Tetralogy of Fallot	1989
Chronopharmacokinetics of beta-receptor blocking drugs of different lipophilicity (propranolol, metoprolol, sotalol, atenolol) in plasma and tissues after single and multiple dosing in the rat. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 330, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Chemical Phenomena; Chemistry, Physical; Half-Life; Heart Rate; Kinetics; Male; Metoprolol; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Structure-Activity Relationship; Time Factors; Tissue Distribution	1985
Brain levels and acute antihypertensive activity of beta-blockers. European journal of clinical pharmacology, 1985, Volume: 28 Suppl Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Brain Chemistry; Cats; Heart Rate; Infusions, Intra-Arterial; Injections, Intravenous; Metoprolol; Sotalol; Time Factors; Tissue Distribution	1985
Single-dose kinetics of oral propranolol, metoprolol, atenolol, and sotalol: relation to lipophilicity. Arzneimittel-Forschung, 1985, Volume: 35, Issue:10 Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Half-Life; Humans; Kinetics; Lipids; Male; Metoprolol; Propranolol; Solubility; Sotalol	1985
Subsidiary class III effects of beta blockers? A comparison of atenolol, metoprolol, nadolol, oxprenolol and sotalol. Cardiovascular research, 1986, Volume: 20, Issue:10 Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Dose-Response Relationship, Drug; Isomerism; Metoprolol; Muscle Contraction; Nadolol; Oxprenolol; Papillary Muscles; Rabbits; Refractory Period, Electrophysiological; Sotalol	1986
Blockade of central beta-adrenoceptors attenuates tremor induced by 5-hydroxytryptamine (5-HT)-receptor activation in rats. Acta physiologica Scandinavica, 1987, Volume: 129, Issue:3 Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Male; Methoxydimethyltryptamines; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sotalol; Tremor	1987
Altered hemodynamic response to dobutamine in relation to the degree of preoperative beta-adrenoceptor blockade. Anesthesiology, 1988, Volume: 68, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Bupranolol; Dobutamine; Hemodynamics; Humans; Metoprolol; Middle Aged; Myocardial Revascularization; Premedication; Sotalol	1988
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:4 Topics: Acute Disease; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Disease; Cyclic AMP; Electrocardiography; Female; Heart Rate; Lactates; Male; Metoprolol; Phosphates; Phosphocreatine; Propranolol; Sotalol; Swine; Time Factors; Ventricular Fibrillation	1986
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion. European heart journal, 1987, Volume: 8 Suppl G Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduction System; Lidocaine; Male; Metoprolol; Myocardial Infarction; Sotalol; Ventricular Fibrillation; Verapamil	1987
[Electrophysiological effects of sotalol on the sinus node, atrium, AV node and his-bundle cells in the rabbit heart]. Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:5 Topics: Action Potentials; Animals; Atrial Function; Atrioventricular Node; Bundle of His; Female; Heart Conduction System; In Vitro Techniques; Male; Metoprolol; Microelectrodes; Rabbits; Sinoatrial Node; Sotalol	1985
[Cholinergic antagonism by beta-blockers. I. Spectrum of interactions]. Bollettino della Societa italiana di biologia sperimentale, 1980, May-15, Volume: 56, Issue:9 Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Ileum; Isoproterenol; Labetalol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Receptors, Cholinergic; Sotalol	1980
Anticholinesterase effect of sotalol. The Indian journal of medical research, 1981, Volume: 73 Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinesterase Inhibitors; In Vitro Techniques; Metoprolol; Muscle Contraction; Physostigmine; Practolol; Propranolol; Ranidae; Sotalol	1981
Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart. Circulation, 1981, Volume: 64, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Male; Metoprolol; Propranolol; Sotalol; Vascular Resistance	1981
[Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension (author's transl)]. Giornale italiano di cardiologia, 1981, Volume: 11, Issue:12 Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Metoprolol; Middle Aged; Prazosin; Renin; Sotalol; Spironolactone	1981
[Therapy of essential tremor with special reference to the use of beta-blockers]. Der Nervenarzt, 1982, Volume: 53, Issue:8 Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bupranolol; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Pindolol; Prognosis; Propranolol; Sotalol; Tremor	1982
Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism. Clinical endocrinology, 1983, Volume: 18, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Humans; Hyperthyroidism; Metoprolol; Middle Aged; Propranolol; Sotalol; Triiodothyronine; Triiodothyronine, Reverse	1983
In vitro stimulation of neutrophil motility by metoprolol and sotalol related to inhibition of both H2O2 production and peroxidase mediated iodination of the cell and leucoattractant. International journal of immunopharmacology, 1980, Volume: 2, Issue:4 Topics: Cell Movement; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Iodides; Lipopolysaccharides; Metoprolol; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidases; Phagocytosis; Propanolamines; Sotalol; Superoxides	1980
Action of sotalol on potential reentrant pathways and ventricular tachyarrhythmias in conscious dogs in the late postmyocardial infarction phase. Circulation, 1983, Volume: 68, Issue:4 Topics: Action Potentials; Animals; Consciousness; Dogs; Electrocardiography; Heart Conduction System; Metoprolol; Myocardial Infarction; Refractory Period, Electrophysiological; Sotalol; Tachycardia; Time Factors	1983
Effects of three bradycardiac drugs on regional myocardial blood flow and function in areas distal to a total or partial coronary occlusion in dogs. Circulation, 1984, Volume: 69, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Collateral Circulation; Coronary Circulation; Coronary Disease; Depression, Chemical; Dogs; Female; Heart Rate; Male; Metoprolol; Propranolol; Sotalol	1984
Differential effects of sotalol and metoprolol on induction of paroxysmal supraventricular tachycardia. The American journal of cardiology, 1984, Apr-01, Volume: 53, Issue:8 Topics: Adult; Aged; Atrioventricular Node; Female; Humans; Male; Metoprolol; Middle Aged; Recurrence; Sotalol; Tachycardia, Paroxysmal	1984
Central pre- and postsynaptic monoamine receptors in antidepressant therapy. Acta psychiatrica Scandinavica. Supplementum, 1981, Volume: 290 Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Catecholamines; Iontophoresis; Male; Metoprolol; Neurons; Propranolol; Rats; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Sotalol; Synapses	1981
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil	1995
Antifibrillary action of class I-IV antiarrhythmic agents in the model of ventricular fibrillation threshold of anesthetized guinea pigs. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atenolol; Benzopyrans; Chromans; Disease Models, Animal; Electric Stimulation; Electrocardiography; Encainide; Ethanolamines; Guinea Pigs; Heart; Heart Conduction System; Injections, Intravenous; Male; Metoprolol; Nebivolol; Phenethylamines; Piperidines; Sotalol; Sulfonamides; Ventricular Fibrillation; Verapamil	1995
Beta-receptor blockade in preventing sudden death. European heart journal, 1993, Volume: 14, Issue:5 Topics: Adrenergic beta-Antagonists; Atenolol; Death, Sudden, Cardiac; Humans; Metoprolol; Practolol; Sotalol; Ventricular Fibrillation	1993
Relative toxicity of beta blockers in overdose. Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:3 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child, Preschool; Databases, Factual; Drug Overdose; Female; Humans; Infant; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Prospective Studies; Seizures; Sotalol	1996
Circadian variation of sustained ventricular tachycardia in patients subject to standard adrenergic blockade. American heart journal, 1997, Volume: 134, Issue:4 Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Circadian Rhythm; Female; Humans; Incidence; Male; Metoprolol; Middle Aged; Regression Analysis; Sotalol; Tachycardia, Ventricular	1997
Sympathotropic drugs and the distribution of 99mTc-hydroxymethylene diphosphonate. Experimental studies in the mouse. Acta radiologica (Stockholm, Sweden : 1987), 1999, Volume: 40, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Bone and Bones; Contrast Media; Ephedrine; Male; Metoprolol; Mice; Mice, Inbred Strains; Propranolol; Radionuclide Imaging; Sotalol; Sympathomimetics; Technetium Tc 99m Medronate; Terbutaline; Tissue Distribution	1999
Hypotension in patients with coronary disease: can profound hypotensive events cause myocardial ischaemic events? Heart (British Cardiac Society), 1999, Volume: 82, Issue:4 Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Ambulatory; Celiprolol; Chi-Square Distribution; Coronary Disease; Diastole; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Female; Humans; Hypotension; Iatrogenic Disease; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Sotalol	1999
Prospective clinical evaluation and follow-up of a cohort of consecutive VT/VF patients, using a staged-care protocol, including coronary arteriography, programmed electrical stimulation and cardiac surgery. Giornale italiano di cardiologia, 1999, Volume: 29, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Surgical Procedures; Cohort Studies; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Defibrillators, Implantable; Electric Stimulation; Follow-Up Studies; Heart Aneurysm; Heart-Lung Transplantation; Humans; Metoprolol; Middle Aged; Prospective Studies; Sotalol; Tachycardia, Ventricular; Time Factors; Ventricular Fibrillation	1999
Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation. Pharmaceutical research, 2003, Volume: 20, Issue:9 Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Animals; Biological Transport; Chromatography, High Pressure Liquid; Drug Carriers; Injections, Intravenous; Iontophoresis; Irritants; Liposomes; Metoprolol; Oxprenolol; Propranolol; Rats; Skin; Skin Absorption; Sotalol; Stereoisomerism; Timolol	2003
Case records of the Massachusetts General Hospital. Case 26-2005. A 48-year-old man with sudden loss of consciousness while jogging. The New England journal of medicine, 2005, Aug-25, Volume: 353, Issue:8 Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Diagnosis, Differential; Humans; Hypertrophy, Left Ventricular; Jogging; Male; Metoprolol; Middle Aged; Risk Factors; Sotalol; Syncope; Ultrasonography; Unconsciousness	2005
Attenuation of the negative inotropic effects of metoprolol at short cycle lengths in humans: comparison with sotalol and verapamil. Journal of the American College of Cardiology, 2006, Sep-19, Volume: 48, Issue:6 Topics: Aged; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Pacing, Artificial; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Pressure; Sotalol; Systole; Time Factors; Ventricular Function, Left; Verapamil	2006
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Mar-01, Volume: 847, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil	2007
Elimination of beta-blockers in sewage treatment plants. Water research, 2007, Volume: 41, Issue:7 Topics: Adrenergic beta-Antagonists; Adsorption; Atenolol; Chromatography, High Pressure Liquid; Kinetics; Metoprolol; Molecular Structure; Propranolol; Sotalol; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification	2007
Mortality and reinfarction among patients using different beta-blockers for secondary prevention after a myocardial infarction. Cardiology, 2009, Volume: 112, Issue:2 Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Bisoprolol; Female; Humans; Kaplan-Meier Estimate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Recurrence; Registries; Sotalol	2009
Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2009, Volume: 25, Issue:6 Topics: Chromatography, High Pressure Liquid; Glucuronides; Humans; Metoprolol; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Sotalol; Sulfates	2009
Atrial fibrillation degenerates into ventricular fibrillation. Journal of the American College of Cardiology, 2010, Mar-09, Volume: 55, Issue:10 Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Defibrillators, Implantable; Disease Progression; Electrocardiography; Humans; Male; Metoprolol; Recurrence; Signal Processing, Computer-Assisted; Sotalol; Ventricular Fibrillation; Ventricular Premature Complexes	2010
High-permeability criterion for BCS classification: segmental/pH dependent permeability considerations. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Caco-2 Cells; Chemistry, Pharmaceutical; Drug Discovery; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Metoprolol; Permeability; Pharmacokinetics; Rats; Rats, Wistar; Sotalol; Therapeutic Equivalency; United States; United States Food and Drug Administration	2010
Pharmacophore modeling for hERG channel facilitation. Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1 Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis	2012
Wide QRS Tachycardia in a young patient. Archives of internal medicine, 2012, Apr-09, Volume: 172, Issue:7 Topics: Anti-Arrhythmia Agents; Arrhythmogenic Right Ventricular Dysplasia; Blood Pressure; Defibrillators, Implantable; Diagnosis, Differential; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Male; Metoprolol; Mexiletine; Sotalol; Tachycardia; Treatment Outcome; Young Adult	2012
Predictors of Pharmacological Therapy of Ectopic Atrial Tachycardia in Children. Pediatric cardiology, 2017, Volume: 38, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Child; Child, Preschool; China; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Logistic Models; Male; Metoprolol; Multivariate Analysis; Propafenone; Retrospective Studies; Sotalol; Tachycardia, Ectopic Atrial; Treatment Outcome	2017
Use of flecainide in combination antiarrhythmic therapy in patients with arrhythmogenic right ventricular cardiomyopathy. Heart rhythm, 2017, Volume: 14, Issue:4 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmogenic Right Ventricular Dysplasia; Catheter Ablation; Combined Modality Therapy; Drug Monitoring; Drug Therapy, Combination; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Humans; Male; Metoprolol; Middle Aged; Recurrence; Sotalol; Treatment Outcome	2017
Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs. Mikrochimica acta, 2019, 06-21, Volume: 186, Issue:7 Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metal-Organic Frameworks; Metoprolol; Propanolamines; Propranolol; Sotalol; Stereoisomerism	2019
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Oct-15, Volume: 1129 Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil	2019
Hyphenation of field-amplified sample injection and transient isotachophoresis in CE for the determination of sotalol and metoprolol in human urine samples. Journal of separation science, 2020, Volume: 43, Issue:11 Topics: Antihypertensive Agents; Electrophoresis, Capillary; Flow Injection Analysis; Healthy Volunteers; Humans; Isotachophoresis; Male; Metoprolol; Sotalol	2020
Evaluating phospholipid- and protein-water partitioning of two groups of chemicals of emerging concern: Diastereo- and enantioselectivity. Journal of hazardous materials, 2022, 05-15, Volume: 430 Topics: Liposomes; Metoprolol; Molecular Docking Simulation; Phospholipids; Propranolol; Serum Albumin, Bovine; Sotalol; Water	2022
Hair analysis for beta-blockers and calcium-channel blockers by using liquid chromatography-tandem mass spectrometry as a tool for monitoring adherence to antihypertensive therapy. Drug testing and analysis, 2022, Volume: 14, Issue:10 Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bisoprolol; Calcium; Calcium Channel Blockers; Chromatography, Liquid; Hair Analysis; Humans; Labetalol; Metoprolol; Nadolol; Nebivolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry	2022