Page last updated: 2024-08-16

sotalol and hydrochlorothiazide

sotalol has been researched along with hydrochlorothiazide in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199010 (38.46)18.7374
1990's2 (7.69)18.2507
2000's6 (23.08)29.6817
2010's8 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Avdeef, A; Tam, KY1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ferguson, HC; McKinney, GR; Perhach, JL1
Bhan, GL; Gupta, RC1
Bennett, JM; Gourassas, J; Konstantinides, S1
Barlow, JB; McKibbin, JK; Millar, RN; Obel, IW; Pocock, WA1
Schoeman, HS; Sommers, DK; van Wyk, M1
Bhigjee, AI; Hoosen, S; Seedat, YK1
Leary, WP; Reyes, AJ; van der Byl, K1
Fillastre, JP; Fourtillan, JB; Ingrand, I; Kher, A; Lefebvre, MA1
Barnes, JN; Drew, PJ; Skehan, JD; Wright, P1
Jäättelä, A1
Millar, RS1
Holzgreve, H; Middeke, M; Richter, WO; Schwandt, P1
Kerchner, K; Sangüeza, OP; Walsh, SN1
Galceran, MT; Huerta-Fontela, M; Ventura, F1

Reviews

1 review(s) available for sotalol and hydrochlorothiazide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for sotalol and hydrochlorothiazide

ArticleYear
Treatment of elderly hypertensives with beta-blocker/thiazide combination.
    Comprehensive gerontology. Section A, Clinical and laboratory sciences, 1987, Volume: 1, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Prospective Studies; Pulse; Sotalol

1987
The effects of two combinations of a beta-blocker and a diuretic on diuresis in normal subjects.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Mar-03, Volume: 65, Issue:9

    Topics: Adult; Atenolol; Chlorthalidone; Clinical Trials as Topic; Diuresis; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Male; Potassium; Sodium; Sotalol; Uric Acid; Urine

1984
Reserpine plus hydrochlorothiazide and sotalol plus hydrochlorothiazide in Black and Indian hypertensive patients.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Jun-09, Volume: 65, Issue:23

    Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Random Allocation; Reserpine; Sotalol

1984
Effects of hydrochlorothiazide plus sotalol on acute urinary electrolyte excretion in normal subjects.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Nov-03, Volume: 66, Issue:18

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Electrolytes; Humans; Hydrochlorothiazide; Male; Random Allocation; Sotalol; Time Factors

1984
Fixed combination of sotalol and hydrochlorothiazide in the treatment of uncomplicated hypertension.
    European journal of clinical pharmacology, 1981, Volume: 19, Issue:6

    Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Sotalol

1981
The effects of antihypertensive combination therapy on lipid and glucose metabolism: hydrochlorothiazide plus sotalol vs. hydrochlorothiazide plus captopril.
    International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Hemoglobin A; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Radioimmunoassay; Sodium Chloride Symporter Inhibitors; Sotalol

1997

Other Studies

19 other study(ies) available for sotalol and hydrochlorothiazide

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Evaluation of antihypertensive agents in the stress-induced hypertensive rat.
    Life sciences, 1975, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Antihypertensive Agents; Chlorisondamine; Disease Models, Animal; Drug Evaluation, Preclinical; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Phentolamine; Propranolol; Rats; Sotalol; Stress, Physiological

1975
Torsade de pointes induced by sotalol and hypokalaemia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Oct-12, Volume: 68, Issue:8

    Topics: Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypokalemia; Male; Middle Aged; Sotalol; Tachycardia

1985
Sotalol, hypokalaemia, syncope, and torsade de pointes.
    British heart journal, 1984, Volume: 51, Issue:2

    Topics: Adult; Aged; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Sotalol; Syncope; Tachycardia

1984
Pharmacokinetics of a fixed combination of sotalol and hydrochlorothiazide in hypertensive patients with moderate renal insufficiency.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:3

    Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Kinetics; Sotalol

1984
Hypokalaemia induced by a combination of a beta-blocker and a thiazide.
    British medical journal (Clinical research ed.), 1982, Jan-09, Volume: 284, Issue:6309

    Topics: Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypokalemia; Middle Aged; Sotalol

1982
Discontinuation of Sotazide.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86, Issue:4

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Contraindications; Drug Combinations; Drug Industry; Drug Utilization; Humans; Hydrochlorothiazide; Sotalol; South Africa; Tachycardia, Ventricular

1996
Challenge. What is your diagnosis? Answer. Primary nodal diffuse large B-cell lymphoma with secondary cutaneous involvement.
    The American Journal of dermatopathology, 2009, Volume: 31, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Disease; Diuretics; Exanthema; Humans; Hydrochlorothiazide; Lisinopril; Lymphoma, Large B-Cell, Diffuse; Male; Platelet Aggregation Inhibitors; Skin Neoplasms; Sotalol; Stents; Ticlopidine

2009
Occurrence and removal of pharmaceuticals and hormones through drinking water treatment.
    Water research, 2011, Volume: 45, Issue:3

    Topics: Atenolol; Carbamazepine; Hormones; Hydrochlorothiazide; Ozone; Pharmaceutical Preparations; Phenytoin; Sotalol; Water Pollutants, Chemical; Water Purification; Water Supply

2011