sotalol has been researched along with clonidine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (45.83) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Aghajanian, GK; Cedarbaum, JM | 2 |
| Daly, JW; Skolnick, P | 1 |
| Aghajanian, GK; Bunney, BS | 1 |
| de Champlain, J; Nadeau, RA; Yamaguchi, N | 1 |
| Saarimaa, H | 1 |
| De Schaepdryver, AF; Lambelin, G; Roba, J | 1 |
| Day, MD; Roach, AG | 1 |
| Enna, SJ; Maggi, A; U'Prichard, DC | 1 |
| Jounela, AJ; Juustila, H; Lilja, M; Mattila, MJ | 1 |
| Garvey, HL; Woodhouse, BL | 1 |
| Arai, J; Okada, S; Shimizu, T; Yamaguchi-Shima, N; Yokotani, K; Yorimitsu, M | 1 |
1 review(s) available for sotalol and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for sotalol and clonidine
| Article | Year |
|---|---|
Combination of clonidine and sotalol in hypertension.
Topics: Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Sotalol | 1976 |
Interaction of clonidine and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol | 1980 |
21 other study(ies) available for sotalol and clonidine
| Article | Year |
|---|---|
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the alpha-antagonist piperoxane.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Ventricles; Clonidine; Epinephrine; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Male; Norepinephrine; Piperidines; Rats; Sotalol | 1976 |
Interaction of clonidine with pre- and post-synaptic adrenergic receptors of rat brain: effects on cyclic AMP-generating systems.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Clonidine; Cyclic AMP; Drug Interactions; Drug Synergism; Hydroxydopamines; Isoproterenol; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred F344; Sotalol | 1976 |
Dopamine"autoreceptors": pharmacological characterization by microiontophoretic single cell recording studies.
Topics: Action Potentials; Animals; Apomorphine; Catecholamines; Clonidine; Dextroamphetamine; Feedback; Iontophoresis; Male; Piperoxan; Rats; Receptors, Dopamine; Sotalol; Substantia Nigra; Synaptic Transmission; Trifluoperazine | 1977 |
Regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors.
Topics: Adrenergic Fibers; Animals; Catecholamines; Clonidine; Desipramine; Dogs; Electric Stimulation; Heart; Hemodynamics; Isoproterenol; Norepinephrine; Phenoxybenzamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sotalol | 1977 |
Catecholamine receptors on locus coeruleus neurons: pharmacological characterization.
Topics: Action Potentials; Animals; Apomorphine; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Male; Neurons; Nordefrin; Norepinephrine; Phenylephrine; Piperoxan; Rats; Receptors, Adrenergic; Sotalol; Trifluoperazine | 1977 |
Antihypertensive activity of four blocking agents in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Disease Models, Animal; Heart Rate; Hydralazine; Hypertension; Male; Propranolol; Rats; Sotalol | 1972 |
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors | 1974 |
beta-Adrenergic regulation of alpha 2-adrenergic receptors in the central nervous system.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Dihydroalprenolol; In Vitro Techniques; Isoproterenol; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sotalol | 1980 |
Reversal of clonidine-induced hypotension by beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Female; Heart Rate; Hypertension; Male; Propranolol; Rabbits; Rats; Sotalol; Time Factors | 1980 |
Role of brain adrenoceptors in the corticortopin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats.
Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Clonidine; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Epinephrine; Injections, Intraventricular; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phentolamine; Rats; Rats, Wistar; Receptors, Adrenergic; Sotalol; Sympathetic Nervous System; Time Factors | 2008 |