sorivudine and 2--3--dideoxythymidine-triphosphate

sorivudine has been researched along with 2--3--dideoxythymidine-triphosphate* in 1 studies

Other Studies

1 other study(ies) available for sorivudine and 2--3--dideoxythymidine-triphosphate

Article	Year
Mechanism of inhibition of DNA synthesis by 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil. Microbiology and immunology, 1993, Volume: 37, Issue:6 The mechanism of the inhibitory action of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl) uracil triphosphate (BV-araUTP) on DNA synthesis by Escherichia coli DNA polymerase I Klenow fragment was studied. Acting as a chain terminator, BV-araUTP inhibited DNA synthesis by Klenow fragment more effectively than 2',3'-dideoxythymidine triphosphate (ddTTP). However, the incorporation sites of BV-araU monophosphate were restricted at consecutive dTMP sequence whereas ddTMP was incorporated at every dTMP site. Topics: Antiviral Agents; Arabinofuranosyluracil; Dideoxynucleotides; DNA Polymerase I; DNA, Bacterial; Escherichia coli; Thymine Nucleotides	1993

Article

Year

Mechanism of inhibition of DNA synthesis by 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.

Microbiology and immunology, 1993, Volume: 37, Issue:6

The mechanism of the inhibitory action of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl) uracil triphosphate (BV-araUTP) on DNA synthesis by Escherichia coli DNA polymerase I Klenow fragment was studied. Acting as a chain terminator, BV-araUTP inhibited DNA synthesis by Klenow fragment more effectively than 2',3'-dideoxythymidine triphosphate (ddTTP). However, the incorporation sites of BV-araU monophosphate were restricted at consecutive dTMP sequence whereas ddTMP was incorporated at every dTMP site.

Topics: Antiviral Agents; Arabinofuranosyluracil; Dideoxynucleotides; DNA Polymerase I; DNA, Bacterial; Escherichia coli; Thymine Nucleotides

1993