sorgoleone has been researched along with tiliroside* in 1 studies
1 other study(ies) available for sorgoleone and tiliroside
| Article | Year |
|---|---|
Isolated compounds from Sorghum bicolor L. inhibit the classical pathway of the complement.
The present study evaluated the anticomplement effects from isolated compounds of Sorghum bicolor in classical pathway complement system. Using column chromatograph, three compounds; Sorgoleone-362 (1), Sorgoleone-360 (2) and Sorgoleone-386 (3) were isolated and evaluated for in vitro anticomplement activity. Sorgoleone-386 showed inhibitory activity against complement system with 50% inhibitory concentrations (IC(50)) values of 148.3μg/ml. This is the first report of anticomplement activity of isolated compounds from Sorghum bicolor. Topics: Animals; Benzoquinones; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cinnamates; Complement Inactivating Agents; Complement Pathway, Classical; Depsides; Flavonoids; Hemolysis; Inhibitory Concentration 50; Lipids; Molecular Structure; Plant Extracts; Plant Roots; Rabbits; Rosmarinic Acid; Sheep; Sorghum | 2012 |