sorbitol and trehalose

sorbitol has been researched along with trehalose in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19905 (7.14)18.7374
1990's8 (11.43)18.2507
2000's22 (31.43)29.6817
2010's27 (38.57)24.3611
2020's8 (11.43)2.80

Authors

AuthorsStudies
Kageyama, T; Takahashi, SY1
Maclean, DJ; Scott, KJ1
Bechinger, B; Macdonald, PM; Seelig, J1
Marples, RR; McGinley, KJ1
Baust, JG1
Perez, E; Pincet, F; Wolfe, J1
Boutron, P; Peyridieu, JF1
Carpenter, JF; Dong, A; Kendrick, BS; Manning, MC; Meyer, JD1
Ali, R; Bellés, JM; García, MJ; Ríos, G; Serrano, R1
Hoekstra, FA; Linders, LJ; van 't Riet, K; Wolkers, WF1
Pope, JM; Wolfe, J; Yoon, YH1
Lindquist, S; Singer, MA1
Grdadolnik, J; Hadzi, D1
Bradley, TJ; Patrick, ML1
Abadias, M; Magan, N; Teixidó, N; Usall, J; Viñas, I1
Choi, SH; Gu, MB; Kim, SW1
Clark, DS; Dordick, JS; Lindsay, JP; Reimer, JA; Ru, MT; Wu, KC1
Chen, TH; Murata, N1
Carninci, P; Hayashizaki, Y; Mizuno, Y; Muramatsu, M; Shiraki, T1
Sankaranarayanan, R; Saraswathi, NT; Vijayan, M1
Chen, HI; Clarridge, JE; Hulten, K1
Hugenholtz, J; Smid, EJ1
Kumar, S; Lee, G; Mauerer, A; Maury, M; Murphy, K1
Chamarthy, SP; Mao, C; Pinal, R1
Hosseinkhani, S; Khajeh, K; Pazhang, M; Ranjbar, B1
Bakaltcheva, I; Hmel, P; O'Sullivan, AM; Ogbu, H1
Cox, GM; Himmelreich, U; Miller, JL; Mylonakis, E; Perfect, JR; Petzold, EW; Rude, T; Toffaletti, D1
Cho, JS; Hong, SM; Joo, SY; Kim, DI; Yoo, JS1
Colinet, H; Gagneul, D; Kostál, V; Lalouette, L; Renault, D1
Caron, V; Descamps, M; Dudognon, E; Willart, JF1
Leuschner, RG; Murray, BS; Portner, DC1
Bonner, MC; Forbes, RT; Getrost, M; Hulse, WL1
Kaino, T; Takagi, H1
Khajeh, K; Naderi-Manesh, H; Nasiripourdori, A; Ranjbar, B1
Prakash, V; Yadav, JK1
Bhowmick, S; Fowler, A; Sitaula, R; Toner, M1
Llabrés, M; Piñero, MJ; Santoveña, A1
Flores-Herrera, O; Guerra-Sánchez, G; Mendoza-Hernández, G; Miranda-Arango, M; Pardo, JP; Salmerón-Santiago, KG1
Azizi, A; Ganjalikhany, MR; Ghodselahi, T; Hoornam, S; Khajeh, K; Mobasheri, H; Ranjbar, B1
Jain, NK; Roy, I; Solanki, VA1
Aminian, M; Fathi-Roudsari, M; Golestani, A; Khajeh, K; Nazari-Robati, M1
Bie, XM; Lu, YP; Lu, ZX; Lv, FX; Zhang, C1
Esfandiary, R; Hu, L; Iyer, V; Joshi, SB; Liyanage, MR; Maisonneuve, J; Meinke, A; Middaugh, CR; Reinisch, C; Volkin, DB1
Bolko, K; Gašperlin, M; Zvonar, A1
Hosseinkhani, S; Khajeh, K; Robatjazi, SM; Saeedinia, AR; Zeinoddini, M1
Lee, G; Lorenzen, E1
Hagura, Y; Kawai, K; Toh, M1
Myers, JK; Silvers, TR1
Hu, W; Liu, Y; Meng, Z; Shi, R; Xiang, H; Xie, Q; Zhan, L1
Elliott, GD; Weng, L1
Bakker, HJ; Groot, CC1
Hernlem, BJ; Hua, SS; Sarreal, SB; Yokoyama, W1
Li, S; Liu, X; Zhang, G; Zhang, J; Zhong, X1
Barnett, GV; Blake, S; Curtis, RA; Kerwin, BA; Qi, W; Razinkov, VI; Roberts, CJ1
Asadikaram, G; Golestani, A; Nazari-Robati, M1
Lan, H; Wang, X; Wen, L; Yin, Z; Zheng, X1
Attri, P; Cho, AE; Ha Choi, E; Kim, M; Koga, K; Sarinont, T; Seo, H; Shiratani, M1
Jun, SH; Kang, NG; Lee, CK; Lee, SH; Park, SG; Yeom, J1
Ambros, S; Hofer, F; Kulozik, U1
Abramov, D; Burré, J; Carnazza, KE; Dittman, JS; Guiberson, NGL; Kharel, P; Pineda, A; Wragg, RT1
Cho, M; Kossowska, D; Kwak, K1
Cloutier, T; Mody, N; Sathish, HA; Sudrik, C; Trout, BL1
Burg, MB; DuMond, JF; Ferraris, JD; He, Y; Khan, SH; Kumar, R; Thompson, EB1
Frey, A; Haindl, R; Kulozik, U; Neumayr, A1
Aravindan, S; Chen, KY; Chen, S; Choudhry, H; Liu, AYC; Molfetta, C1
Ahmad, A; Mishra, R2
Cristiglio, V; Shalaev, E; Sztucki, M; Wu, C1
Fan, Y; Ge, Y; Guo, M; Huang, R; Ji, X; Li, C; Sun, L; Zhu, J1
Bidart, GN; Gharabli, H; Welner, DH1

Reviews

3 review(s) available for sorbitol and trehalose

ArticleYear
[Carbohydrate metabolism of diapausing insects (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1975, Volume: 20, Issue:14

    Topics: Acid Phosphatase; Adaptation, Physiological; Animals; Bombyx; Carbohydrate Metabolism; Cyclic AMP; Diptera; Female; Glycerol; Glycogen; Glycogen Synthase; Hemolymph; Insecta; Lactates; Ovum; Phosphorylases; Protein Kinases; Sorbitol; Trehalase; Trehalose

1975
Enhancement of tolerance of abiotic stress by metabolic engineering of betaines and other compatible solutes.
    Current opinion in plant biology, 2002, Volume: 5, Issue:3

    Topics: Adaptation, Physiological; Betaine; Choline; Fructans; Genetic Engineering; Glycine; Mannitol; Oxidative Stress; Plants; Plants, Genetically Modified; Proline; Sorbitol; Stress, Mechanical; Trehalose

2002
Nutraceutical production with food-grade microorganisms.
    Current opinion in biotechnology, 2002, Volume: 13, Issue:5

    Topics: Antioxidants; Bacteria; Carbohydrate Metabolism; Folic Acid; Hexoses; Humans; Intestines; Lactococcus lactis; Mannitol; Probiotics; Riboflavin; Sorbitol; Species Specificity; Trehalose; Vitamin B 12

2002

Trials

1 trial(s) available for sorbitol and trehalose

ArticleYear
Freeze-dried whole plasma: evaluating sucrose, trehalose, sorbitol, mannitol and glycine as stabilizers.
    Thrombosis research, 2007, Volume: 120, Issue:1

    Topics: Blood Preservation; Excipients; Freeze Drying; Glycine; Humans; Mannitol; Plasma; Sorbitol; Sucrose; Trehalose

2007

Other Studies

66 other study(ies) available for sorbitol and trehalose

ArticleYear
Identification of glucitol (sorbitol) and ribitol in a rust fungus, Puccinia graminis f. sp. tritici.
    Journal of general microbiology, 1976, Volume: 97, Issue:1

    Topics: Basidiomycota; Carbohydrates; Glucose; Plant Diseases; Solubility; Sorbitol; Spores, Fungal; Sugar Alcohols; Trehalose; Triticum

1976
Deuterium NMR studies of the interactions of polyhydroxyl compounds and of glycolipids with lipid model membranes.
    Biochimica et biophysica acta, 1988, Aug-18, Volume: 943, Issue:2

    Topics: Ethylene Glycol; Ethylene Glycols; Glycerol; Glycolipids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Conformation; Phosphatidylcholines; Sorbitol; Trehalose

1988
Corynebacterium acnes and other anaerobic diphtheroids from human skin.
    Journal of medical microbiology, 1974, Volume: 7, Issue:3

    Topics: Acne Vulgaris; Anaerobiosis; Axilla; Back; Bacteriophage Typing; Caseins; Cheek; Corynebacterium; Deoxyribonucleases; Hemolysis; Humans; Nitrates; Pepsin A; Propionibacterium acnes; Scalp; Skin; Sorbitol; Sucrose; Trehalose

1974
Protective agents: regulation of synthesis.
    Cryobiology, 1983, Volume: 20, Issue:3

    Topics: Adaptation, Physiological; Animals; Cold Temperature; Cryoprotective Agents; Diptera; Disaccharides; Glycerol; Seasons; Sorbitol; Trehalose

1983
Do trehalose and dimethyl sulfoxide affect intermembrane forces?
    Cryobiology, 1994, Volume: 31, Issue:6

    Topics: Adhesiveness; Chemical Phenomena; Chemistry, Physical; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; In Vitro Techniques; Lipid Bilayers; Osmosis; Phosphatidylcholines; Solutions; Sorbitol; Surface Properties; Trehalose

1994
Reduction in toxicity for red blood cells in buffered solutions containing high concentrations of 2,3-butanediol by trehalose, sucrose, sorbitol, or mannitol.
    Cryobiology, 1994, Volume: 31, Issue:4

    Topics: Blood Preservation; Butylene Glycols; Cryopreservation; Cryoprotective Agents; Erythrocytes; Evaluation Studies as Topic; Hemolysis; Humans; In Vitro Techniques; Mannitol; Solutions; Sorbitol; Sucrose; Time Factors; Trehalose

1994
Effect of secondary structure on the activity of enzymes suspended in organic solvents.
    Archives of biochemistry and biophysics, 1996, Oct-15, Volume: 334, Issue:2

    Topics: Chymotrypsin; Freeze Drying; Protein Structure, Secondary; Solvents; Sorbitol; Spectrophotometry, Infrared; Subtilisins; Trehalose

1996
Comparative physiology of salt tolerance in Candida tropicalis and Saccharomyces cerevisiae.
    Microbiology (Reading, England), 1997, Volume: 143 ( Pt 4)

    Topics: Adaptation, Physiological; Candida; Glycerol; Homeostasis; Lithium Chloride; Osmotic Pressure; Potassium Chloride; Saccharomyces cerevisiae; Salts; Sodium Chloride; Sorbitol; Species Specificity; Trehalose

1997
Effect of added carbohydrates on membrane phase behavior and survival of dried Lactobacillus plantarum.
    Cryobiology, 1997, Volume: 35, Issue:1

    Topics: Carbohydrates; Cell Membrane; Desiccation; Food Microbiology; Lactobacillus; Liposomes; Maltose; Molecular Structure; Phospholipids; Sorbitol; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Trehalose

1997
The effects of solutes on the freezing properties of and hydration forces in lipid lamellar phases.
    Biophysical journal, 1998, Volume: 74, Issue:4

    Topics: Biophysical Phenomena; Biophysics; Deuterium Oxide; Dimethyl Sulfoxide; Freezing; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Osmosis; Solutions; Sorbitol; Sucrose; Trehalose; Water

1998
Multiple effects of trehalose on protein folding in vitro and in vivo.
    Molecular cell, 1998, Volume: 1, Issue:5

    Topics: Animals; Betaine; Coleoptera; Fluorescence Polarization; Fungal Proteins; Genes, Reporter; Glucose; Glycerol; Heat-Shock Proteins; Luciferases; Maltose; Mannitol; Molecular Chaperones; Proline; Protein Folding; Sorbitol; Sucrose; Temperature; Trehalose; Yeasts

1998
FT infrared and Raman investigation of saccharide-phosphatidylcholine interactions using novel structure probes.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 1998, Volume: 54A, Issue:12

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Carbohydrate Conformation; Glucose; Hydrogen Bonding; Oligosaccharides; Raffinose; Sorbitol; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Trehalose

1998
Regulation of compatible solute accumulation in larvae of the mosquito Culex tarsalis: osmolarity versus salinity.
    The Journal of experimental biology, 2000, Volume: 203, Issue:Pt 4

    Topics: Adaptation, Physiological; Animals; Culex; Hemolymph; Homeostasis; Larva; Osmolar Concentration; Proline; Sodium Chloride; Sorbitol; Trehalose

2000
Improving water stress tolerance of the biocontrol yeast Candida sake grown in molasses-based media by physiological manipulation.
    Canadian journal of microbiology, 2001, Volume: 47, Issue:2

    Topics: Candida; Culture Media; Glucose; Glycerol; Molasses; Polymers; Proline; Sodium Chloride; Sorbitol; Trehalose; Water

2001
Some observations in freeze-drying of recombinant bioluminescent Escherichia coli for toxicity monitoring.
    Journal of biotechnology, 2001, Jun-15, Volume: 88, Issue:2

    Topics: Biosensing Techniques; Chlorophenols; Cryoprotective Agents; Escherichia coli; Freeze Drying; Luminescent Measurements; Mannitol; Microbiological Techniques; Microscopy, Electron, Scanning; Sorbitol; Sucrose; Toxicity Tests; Trehalose

2001
Towards more active biocatalysts in organic media: increasing the activity of salt-activated enzymes.
    Biotechnology and bioengineering, 2001, Oct-20, Volume: 75, Issue:2

    Topics: Binding Sites; Buffers; Catalysis; Enzyme Activation; Esterification; Freeze Drying; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Microscopy, Electron, Scanning; Organic Chemicals; Polyethylene Glycols; Potassium Chloride; Salts; Sodium Acetate; Sodium Bicarbonate; Solvents; Sorbitol; Subtilisin; Sucrose; Trehalose; Water

2001
Extra-long first-strand cDNA synthesis.
    BioTechniques, 2002, Volume: 32, Issue:5

    Topics: Animals; Buffers; Cloning, Molecular; DNA, Complementary; Gene Library; Mice; Reverse Transcriptase Polymerase Chain Reaction; Sorbitol; Trehalose

2002
Effect of stabilizing additives on the structure and hydration of proteins: a study involving monoclinic lysozyme.
    Acta crystallographica. Section D, Biological crystallography, 2002, Volume: 58, Issue:Pt 7

    Topics: Animals; Chickens; Crystallography, X-Ray; Glycerol; Muramidase; Proteins; Sodium Chloride; Sorbitol; Sucrose; Temperature; Trehalose; Water

2002
Taxonomic subgroups of Pasteurella multocida correlate with clinical presentation.
    Journal of clinical microbiology, 2002, Volume: 40, Issue:9

    Topics: Bacterial Typing Techniques; DNA, Ribosomal; Humans; Pasteurella Infections; Pasteurella multocida; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Respiratory Tract Infections; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sorbitol; Trehalose; Wound Infection

2002
Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 59, Issue:2

    Topics: Humans; Immunoglobulin G; Proteins; Sorbitol; Spectroscopy, Fourier Transform Infrared; Trehalose

2005
Time-dependence of molecular mobility during structural relaxation and its impact on organic amorphous solids: an investigation based on a calorimetric approach.
    Pharmaceutical research, 2006, Volume: 23, Issue:8

    Topics: Algorithms; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Crystallization; Indomethacin; Nonlinear Dynamics; Pharmaceutical Preparations; Sorbitol; Sucrose; Temperature; Thermodynamics; Trehalose

2006
Effects of water-miscible solvents and polyhydroxy compounds on the structure and enzymatic activity of thermolysin.
    Journal of biotechnology, 2006, Dec-15, Volume: 127, Issue:1

    Topics: 1-Propanol; 2-Propanol; Dimethyl Sulfoxide; Dimethylformamide; Enzyme Stability; Glycerol; Hot Temperature; Kinetics; Protein Denaturation; Solvents; Sorbitol; Thermolysin; Trehalose

2006
Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans.
    Infection and immunity, 2006, Volume: 74, Issue:10

    Topics: Animals; Cryptococcosis; Cryptococcus neoformans; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Glucosyltransferases; Glycolysis; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Mutation; Rabbits; Sorbitol; Sugar Phosphates; Temperature; Trehalase; Trehalose; Virulence

2006
Cryopreservation of transgenic rice suspension cells producing recombinant hCTLA4Ig.
    Applied microbiology and biotechnology, 2007, Volume: 73, Issue:6

    Topics: Abatacept; Cell Survival; Cryopreservation; Humans; Immunoconjugates; Mannitol; Oryza; Plants, Genetically Modified; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride; Sorbitol; Sucrose; Time Factors; Trehalose

2007
Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.
    The FEBS journal, 2007, Volume: 274, Issue:7

    Topics: Acclimatization; Alanine; Amino Acids; Amino Acids, Essential; Animals; Arginine; Body Temperature; Cold Temperature; Glucose; Glutamic Acid; Glutamine; Glycerol; Inositol; Lysine; Proline; Ribitol; Sorbitol; Survival Analysis; Temperature; Tenebrio; Threonine; Trehalose; Tropical Climate; Valine

2007
Transformation of pharmaceutical compounds upon milling and comilling: the role of T(g).
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:5

    Topics: Anti-Inflammatory Agents; Budesonide; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Drug Stability; Excipients; Lactose; Mannitol; Models, Chemical; Sorbitol; Technology, Pharmaceutical; Transition Temperature; Trehalose; Water

2007
Optimising the viability during storage of freeze-dried cell preparations of Campylobacter jejuni.
    Cryobiology, 2007, Volume: 54, Issue:3

    Topics: Campylobacter jejuni; Cryoprotective Agents; Freeze Drying; Inositol; Microbial Viability; Peptones; Sorbitol; Trehalose

2007
Do co-spray dried excipients offer better lysozyme stabilisation than single excipients?
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Mar-03, Volume: 33, Issue:3

    Topics: Calorimetry, Differential Scanning; Drug Compounding; Drug Stability; Excipients; Mannitol; Micrococcus; Muramidase; Sorbitol; Thermogravimetry; Trehalose; X-Ray Diffraction

2008
Gene expression profiles and intracellular contents of stress protectants in Saccharomyces cerevisiae under ethanol and sorbitol stresses.
    Applied microbiology and biotechnology, 2008, Volume: 79, Issue:2

    Topics: Ethanol; Gene Expression Profiling; Gene Expression Regulation, Fungal; Glycerol; Glycerolphosphate Dehydrogenase; Phosphoric Monoester Hydrolases; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sorbitol; Trehalose

2008
Co-solvent effects on structure and function properties of savinase: solvent-induced thermal stabilization.
    International journal of biological macromolecules, 2009, May-01, Volume: 44, Issue:4

    Topics: Amides; Bacillus; Bacteriolysis; Enzyme Activation; Enzyme Stability; Protein Binding; Serine Endopeptidases; Solvents; Sorbitol; Temperature; Trehalose

2009
Thermal stability of alpha-amylase in aqueous cosolvent systems.
    Journal of biosciences, 2009, Volume: 34, Issue:3

    Topics: alpha-Amylases; Buffers; Enzyme Stability; Glycerol; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Protein Denaturation; Solvents; Sorbitol; Spectrometry, Fluorescence; Starch; Substrate Specificity; Sucrose; Surface Properties; Temperature; Thermodynamics; Trehalose; Water

2009
A study of the effect of sorbitol on osmotic tolerance during partial desiccation of bovine sperm.
    Cryobiology, 2010, Volume: 60, Issue:3

    Topics: Animals; Cattle; Desiccation; Male; Organ Preservation Solutions; Osmosis; Osmotic Pressure; Semen Preservation; Sorbitol; Sperm Motility; Spermatozoa; Trehalose

2010
Comparison between DSC and TMDSC in the investigation into frozen aqueous cryoprotectants solutions.
    Drug development and industrial pharmacy, 2010, Volume: 36, Issue:12

    Topics: Calorimetry, Differential Scanning; Cryoprotective Agents; Crystallization; Freezing; Glycine; Hot Temperature; Mannitol; Phase Transition; Solutions; Sorbitol; Sucrose; Transition Temperature; Trehalose; Water

2010
Response to osmotic stress and temperature of the fungus Ustilago maydis.
    Archives of microbiology, 2011, Volume: 193, Issue:10

    Topics: Adaptation, Physiological; Cycloheximide; Fungal Proteins; Heat-Shock Response; Hot Temperature; Osmotic Pressure; Protein Synthesis Inhibitors; Proteome; Sodium Chloride; Sorbitol; Tandem Mass Spectrometry; Trehalase; Trehalose; Ustilago

2011
Effects of trehalose and sorbitol on the activity and structure of Pseudomonas cepacia lipase: spectroscopic insight.
    International journal of biological macromolecules, 2011, Nov-01, Volume: 49, Issue:4

    Topics: Burkholderia cepacia; Circular Dichroism; Gold; Hydrolysis; Lipase; Metal Nanoparticles; Sorbitol; Spectrometry, Fluorescence; Structure-Activity Relationship; Surface Plasmon Resonance; Trehalose

2011
Stabilization of tetanus toxoid formulation containing aluminium hydroxide adjuvant against agitation.
    International journal of pharmaceutics, 2012, Feb-28, Volume: 423, Issue:2

    Topics: Adjuvants, Immunologic; Adsorption; Aluminum Hydroxide; Arginine; Chemistry, Pharmaceutical; Drug Compounding; Drug Stability; Enzyme-Linked Immunosorbent Assay; Excipients; Gels; Glucose; Protein Denaturation; Protein Stability; Sorbitol; Stress, Mechanical; Surface Properties; Technology, Pharmaceutical; Tetanus Toxoid; Trehalose

2012
Co-solvent mediated thermal stabilization of chondroitinase ABC I form Proteus vulgaris.
    International journal of biological macromolecules, 2012, Apr-01, Volume: 50, Issue:3

    Topics: Chondroitin ABC Lyase; Cloning, Molecular; Enzyme Stability; Glycerol; Protein Denaturation; Proteus vulgaris; Solvents; Sorbitol; Temperature; Time Factors; Trehalose

2012
Study on the electro-transformation conditions of improving transformation efficiency for Bacillus subtilis.
    Letters in applied microbiology, 2012, Volume: 55, Issue:1

    Topics: Bacillus subtilis; Culture Media; DNA; Electroporation; Genetic Techniques; Mannitol; Plasmids; Sorbitol; Transformation, Genetic; Trehalose

2012
Preformulation characterization of an aluminum salt-adjuvanted trivalent recombinant protein-based vaccine candidate against Streptococcus pneumoniae.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:9

    Topics: Adhesins, Bacterial; Adjuvants, Immunologic; Adsorption; Aluminum Compounds; Aluminum Hydroxide; Bacterial Proteins; Chemistry, Pharmaceutical; Circular Dichroism; Excipients; Hydrogen-Ion Concentration; Light; Lipoproteins; Phosphates; Pneumococcal Vaccines; Protein Conformation; Protein Denaturation; Protein Serine-Threonine Kinases; Protein Stability; Scattering, Radiation; Sorbitol; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Streptococcus pneumoniae; Sucrose; Technology, Pharmaceutical; Temperature; Trehalose; Vaccines, Synthetic

2012
Microencapsulation of self-microemulsifying systems: optimization of shell-formation phase and hardening process.
    International journal of pharmaceutics, 2012, Nov-01, Volume: 437, Issue:1-2

    Topics: Alginates; Drug Compounding; Drug Delivery Systems; Furosemide; Glucuronic Acid; Glycerides; Glycerol; Hexuronic Acids; Lactose; Mannitol; Oleic Acids; Organic Chemicals; Pectins; Sorbitol; Trehalose; Triglycerides

2012
Stabilisation of recombinant aequorin by polyols: activity, thermostability and limited proteolysis.
    Applied biochemistry and biotechnology, 2013, Volume: 170, Issue:2

    Topics: Aequorin; Apoproteins; Calcium; Escherichia coli; Glycerol; Luminescent Proteins; Peptide Hydrolases; Polymers; Protein Stability; Proteolysis; Recombinant Proteins; Sorbitol; Temperature; Trehalose

2013
Trehalose and sorbitol alter the kinetic pattern of inactivation of glutamate dehydrogenase during drying in levitated microdroplets.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:12

    Topics: Animals; Cattle; Desiccation; Enzyme Activation; Enzyme Stability; Glutamate Dehydrogenase; Kinetics; Particle Size; Phase Transition; Sorbitol; Trehalose; Water

2013
Effect of sugar composition on the water sorption and softening properties of cookie.
    Food chemistry, 2014, Feb-15, Volume: 145

    Topics: Adsorption; Calorimetry, Differential Scanning; Chemical Phenomena; Dietary Sucrose; Elasticity; Fast Foods; Food Quality; Food Storage; Hardness; Japan; Rheology; Sorbitol; Sweetening Agents; Temperature; Trehalose; Water

2014
Osmolyte effects on the self-association of concanavalin A: testing theoretical models.
    Biochemistry, 2013, Dec-23, Volume: 52, Issue:51

    Topics: Betaine; Circular Dichroism; Concanavalin A; Dimerization; Hydrogen-Ion Concentration; Indicators and Reagents; Methylamines; Models, Molecular; Osmolar Concentration; Proline; Protein Interaction Domains and Motifs; Protein Stability; Sarcosine; Secondary Metabolism; Sorbitol; Sucrose; Thermodynamics; Titrimetry; Trehalose; Urea

2013
Effects of temperature and additives on the thermal stability of glucoamylase from Aspergillus niger.
    Journal of microbiology and biotechnology, 2015, Volume: 25, Issue:1

    Topics: Aspergillus niger; Circular Dichroism; Enzyme Stability; Glucan 1,4-alpha-Glucosidase; Glycosylation; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Weight; Sorbitol; Spectrometry, Fluorescence; Trehalose

2015
Determination of the relaxation characteristics of sugar glasses embedded in microfiber substrates.
    Materials science & engineering. C, Materials for biological applications, 2014, Volume: 44

    Topics: Desiccation; Glass; Sorbitol; Sucrose; Temperature; Trehalose; Water

2014
A femtosecond mid-infrared study of the dynamics of water in aqueous sugar solutions.
    Physical chemistry chemical physics : PCCP, 2015, Apr-07, Volume: 17, Issue:13

    Topics: Carbohydrates; Glucose; Molecular Dynamics Simulation; Solutions; Sorbitol; Spectrophotometry, Infrared; Time Factors; Trehalose; Water

2015
Intracellular trehalose and sorbitol synergistically promoting cell viability of a biocontrol yeast, Pichia anomala, for aflatoxin reduction.
    World journal of microbiology & biotechnology, 2015, Volume: 31, Issue:5

    Topics: Aflatoxins; Aspergillus flavus; Chromatography, High Pressure Liquid; Culture Media; Microbial Viability; Pest Control, Biological; Pichia; Preservation, Biological; Sorbitol; Time Factors; Trehalose

2015
Metabolic characterization of natural and cultured Ophicordyceps sinensis from different origins by 1H NMR spectroscopy.
    Journal of pharmaceutical and biomedical analysis, 2015, Nov-10, Volume: 115

    Topics: Alanine; Cordyceps; Discriminant Analysis; Fermentation; Hydroxyproline; Least-Squares Analysis; Mannitol; Metabolomics; Multivariate Analysis; Principal Component Analysis; Proton Magnetic Resonance Spectroscopy; Sorbitol; Trehalose

2015
Osmolyte Effects on Monoclonal Antibody Stability and Concentration-Dependent Protein Interactions with Water and Common Osmolytes.
    The journal of physical chemistry. B, 2016, Apr-07, Volume: 120, Issue:13

    Topics: Antibodies, Monoclonal; Immunoglobulin G; Osmolar Concentration; Polyethylene Glycols; Protein Stability; Sorbitol; Sucrose; Thermodynamics; Trehalose; Water

2016
Improvement of proteolytic and oxidative stability of Chondroitinase ABC I by cosolvents.
    International journal of biological macromolecules, 2016, Volume: 91

    Topics: Bacterial Proteins; Chondroitin ABC Lyase; Chymotrypsin; Enzyme Stability; Glycerol; Oxidation-Reduction; Proteolysis; Proteus vulgaris; Solvents; Sorbitol; Trehalose; Trypsin

2016
Bilateral Effects of Excipients on Protein Stability: Preferential Interaction Type of Excipient and Surface Aromatic Hydrophobicity of Protein.
    Pharmaceutical research, 2017, Volume: 34, Issue:7

    Topics: Arginine; Chemistry, Pharmaceutical; Colloids; Excipients; Humans; Hydrophobic and Hydrophilic Interactions; Ovalbumin; Phenylalanine; Propylene Glycols; Protein Conformation; Protein Stability; Serum Albumin, Bovine; Solubility; Solutions; Sorbitol; Sucrose; Surface Properties; Trehalose; Tryptophan; Tyrosine

2017
The protective action of osmolytes on the deleterious effects of gamma rays and atmospheric pressure plasma on protein conformational changes.
    Scientific reports, 2017, 08-18, Volume: 7, Issue:1

    Topics: Atmospheric Pressure; Electricity; Gamma Rays; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Myoglobin; Plasma Gases; Protective Agents; Protein Denaturation; Protein Structure, Secondary; Solutions; Sorbitol; Trehalose; Urea

2017
Optical clearing agent reduces scattering of light by the stratum corneum and modulates the physical properties of coenocytes via hydration.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2018, Volume: 24, Issue:3

    Topics: Epidermis; Fructose; Glycerol; Humans; Hyaluronic Acid; Hygroscopic Agents; Imaging, Three-Dimensional; In Vitro Techniques; Keratinocytes; Light; Microscopy, Confocal; Nonlinear Optical Microscopy; Skin Absorption; Sodium Chloride; Sorbitol; Spectroscopy, Fourier Transform Infrared; Sugar Alcohols; Trehalose; Urea; Water

2018
Protective effect of sugars on storage stability of microwave freeze-dried and freeze-dried Lactobacillus paracasei F19.
    Journal of applied microbiology, 2018, Volume: 125, Issue:4

    Topics: Freeze Drying; Lacticaseibacillus paracasei; Microbial Viability; Microwaves; Polysaccharides; Preservation, Biological; Sorbitol; Trehalose

2018
Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
    Nature communications, 2018, 09-28, Volume: 9, Issue:1

    Topics: Animals; Brain Diseases; Caenorhabditis elegans Proteins; Cell Line, Tumor; Cells, Cultured; HEK293 Cells; Humans; Mice, Knockout; Munc18 Proteins; Mutation, Missense; Neurons; Organic Chemicals; Phenylbutyrates; Protein Aggregates; Protein Aggregation, Pathological; Saccharomyces cerevisiae Proteins; Sorbitol; Trehalose

2018
Do Osmolytes Impact the Structure and Dynamics of Myoglobin?
    Molecules (Basel, Switzerland), 2018, Dec-03, Volume: 23, Issue:12

    Topics: Betaine; Circular Dichroism; Inositol; Myoglobin; Osmosis; Protein Stability; Sorbitol; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Taurine; Temperature; Trehalose

2018
Molecular Computations of Preferential Interaction Coefficients of IgG1 Monoclonal Antibodies with Sorbitol, Sucrose, and Trehalose and the Impact of These Excipients on Aggregation and Viscosity.
    Molecular pharmaceutics, 2019, 08-05, Volume: 16, Issue:8

    Topics: Antibodies, Monoclonal; Buffers; Chemistry, Pharmaceutical; Drug Storage; Excipients; Freeze Drying; Hydrophobic and Hydrophilic Interactions; Immunoglobulin G; Molecular Dynamics Simulation; Protein Aggregates; Sorbitol; Sucrose; Trehalose; Viscosity

2019
NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 08-18, Volume: 117, Issue:33

    Topics: Escherichia coli; Intrinsically Disordered Proteins; Osmotic Pressure; Protein Binding; Protein Folding; Sodium Chloride; Sorbitol; Transcription Factors; Trehalose

2020
Impact of cultivation strategy, freeze-drying process, and storage conditions on survival, membrane integrity, and inactivation kinetics of Bifidobacterium longum.
    Folia microbiologica, 2020, Volume: 65, Issue:6

    Topics: Bifidobacterium longum; Cell Culture Techniques; Culture Media; Desiccation; Freeze Drying; Humans; Hydrogen-Ion Concentration; Kinetics; Microbial Viability; Polysaccharides; Probiotics; Sorbitol; Temperature; Trehalose

2020
Osmolytes dynamically regulate mutant Huntingtin aggregation and CREB function in Huntington's disease cell models.
    Scientific reports, 2020, 09-23, Volume: 10, Issue:1

    Topics: Animals; Autophagy; Cyclic AMP Response Element-Binding Protein; Gene Knockdown Techniques; Glycerol; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Huntingtin Protein; Huntington Disease; Mutation; Osmolar Concentration; PC12 Cells; Protein Aggregation, Pathological; Protein Folding; Rats; Sorbitol; Sucrose; Trehalose

2020
Differential effect of polyol and sugar osmolytes on the refolding of homologous alpha amylases: A comparative study.
    Biophysical chemistry, 2022, Volume: 281

    Topics: alpha-Amylases; Glycerol; Polymers; Sorbitol; Sugars; Trehalose; Urea

2022
Impact of lyoprotectors on protein-protein separation in the solid state: Neutron- and X-ray-scattering investigation.
    Biochimica et biophysica acta. General subjects, 2022, Volume: 1866, Issue:5

    Topics: Glucose; Muramidase; Neutrons; Proteins; Scattering, Small Angle; Sorbitol; Trehalose; X-Ray Diffraction; X-Rays

2022
Trehalose Regulates Starch, Sorbitol, and Energy Metabolism to Enhance Tolerance to Blue Mold of "Golden Delicious" Apple Fruit.
    Journal of agricultural and food chemistry, 2022, May-11, Volume: 70, Issue:18

    Topics: Anacardiaceae; Energy Metabolism; Fruit; L-Iditol 2-Dehydrogenase; Malus; Penicillium; Sorbitol; Starch; Sugars; Trehalose

2022
Polyol and sugar osmolytes stabilize the molten globule state of α-lactalbumin and inhibit amyloid fibril formation.
    Biochimica et biophysica acta. Proteins and proteomics, 2022, 11-01, Volume: 1870, Issue:11-12

    Topics: Amyloid; Animals; Cattle; Circular Dichroism; Glycerol; Humans; Lactalbumin; Molecular Chaperones; Polymers; Prions; Protein Aggregates; Protein Folding; Sorbitol; Sugars; Trehalose

2022
Functional characterization of the phosphotransferase system in Parageobacillus thermoglucosidasius.
    Scientific reports, 2023, 05-02, Volume: 13, Issue:1

    Topics: Acetylglucosamine; Arbutin; Bacteria; Bacterial Proteins; Carbohydrates; Mannitol; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphotransferases; Sorbitol; Trehalose

2023