sorbitol and propofol

sorbitol has been researched along with propofol in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buijs, EJ; van Zuylen, HJ1
Babl, J; Doenicke, AW; Klotz, U; Kugler, J; O'Connor, M; Rau, J; Roizen, MF1
Cox, EH; Danhof, M; Knibbe, CA; Koster, VS; Kuks, PF; Lange, R; Langemeijer, HJ; Langemeijer, MW; Lie-A-Huen, L; Tukker, EE1
Aarts, LP; Danhof, M; Knibbe, CA; Kuks, PF; Naber, H1
Aarts, LP; Boom, FA; Bras, LJ; Danhof, M; Knibbe, CA; Peeters, MY; Tibboel, D1
Chaki, T; Hirata, N; Tachibana, S; Tokinaga, Y; Yamakage, M; Yoshikawa, Y1
Chen, MS; Lin, WC; Lu, PK; Sheu, SM; Shin, HC; Sie, SR1
Chen, HF; Chen, MS; Fang, CL; Lin, WC; Sheu, SM; Yang, KS1

Reviews

1 review(s) available for sorbitol and propofol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for sorbitol and propofol

ArticleYear
Pharmacokinetics and pharmacodynamics of propofol in a new solvent.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Combinations; Electroencephalography; Fat Emulsions, Intravenous; Humans; Injections, Intravenous; Male; Pain; Phospholipids; Propofol; Sleep; Sorbitol

1997
Long-term sedation with propofol 60 mg ml(-1) vs. propofol 10 mg(-1) ml in critically ill, mechanically ventilated patients.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Conscious Sedation; Critical Illness; Drug Combinations; Enteral Nutrition; Fat Emulsions, Intravenous; Humans; Infusions, Intravenous; Metabolic Clearance Rate; Middle Aged; Phospholipids; Propofol; Prospective Studies; Respiration, Artificial; Sorbitol; Time Factors; Triglycerides

2004
Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

    Topics: Aged; Anesthetics; Cardiac Output; Critical Illness; Female; Humans; Liver; Male; Middle Aged; Nonlinear Dynamics; Pilot Projects; Propofol; Software; Sorbitol; Thermodilution

2008

Other Studies

8 other study(ies) available for sorbitol and propofol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Metabolic consequences of a sorbitol overdose during neurosurgery.
    Journal of neurosurgical anesthesiology, 1997, Volume: 9, Issue:1

    Topics: Acidosis, Lactic; Adenosine Diphosphate; Adenosine Triphosphate; Anesthesia, General; Anesthetics, General; Blood Glucose; Dexamethasone; Diuretics, Osmotic; Drug Overdose; Electrolytes; Etomidate; Humans; Insulin; Insulin, Regular, Pork; Intracranial Aneurysm; Lactates; Male; Middle Aged; Neurosurgery; Phosphates; Propofol; Pseudotumor Cerebri; Sorbitol; Sufentanil; Uric Acid

1997
Influence of different fat emulsion-based intravenous formulations on the pharmacokinetics and pharmacodynamics of propofol.
    Pharmaceutical research, 1998, Volume: 15, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Drug Combinations; Electroencephalography; Fat Emulsions, Intravenous; Infusions, Intravenous; Male; Models, Statistical; Phospholipids; Propofol; Rats; Rats, Wistar; Sorbitol; Statistics, Nonparametric

1998
Lipid emulsion, but not propofol, induces skeletal muscle damage and lipid peroxidation.
    Journal of anesthesia, 2019, Volume: 33, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Antioxidants; Drug Combinations; Infusions, Intravenous; Lipid Peroxidation; Male; Malondialdehyde; Muscle, Skeletal; Phospholipids; Propofol; Rats; Rats, Wistar; Sorbitol

2019
Lipofundin Mediates the Major Inhibition of Intravenous Propofol in IL-1β Secretion and Phagocytosis of Staphylococcus aureus-Infected Macrophages.
    Lipids, 2020, Volume: 55, Issue:1

    Topics: Administration, Intravenous; Animals; Down-Regulation; Drug Combinations; Gene Expression Regulation; Interleukin-1beta; Macrophages; Mice; Phagocytosis; Phospholipids; Propofol; RAW 264.7 Cells; Reactive Oxygen Species; Sorbitol; Staphylococcus aureus

2020
Lipofundin mediates major inhibition of intravenous propofol on phorbol myristate acetate and Escherichia coli-induced neutrophil extracellular traps.
    Molecular biology reports, 2022, Volume: 49, Issue:7

    Topics: Administration, Intravenous; Drug Combinations; Emulsions; Escherichia coli; Extracellular Signal-Regulated MAP Kinases; Extracellular Traps; Humans; Hypochlorous Acid; Neutrophils; Phospholipids; Propofol; Reactive Oxygen Species; Solvents; Sorbitol; Tetradecanoylphorbol Acetate

2022