sorbitol has been researched along with betaine in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (10.67) | 18.7374 |
| 1990's | 33 (44.00) | 18.2507 |
| 2000's | 20 (26.67) | 29.6817 |
| 2010's | 12 (16.00) | 24.3611 |
| 2020's | 2 (2.67) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Deguchi, E; Koumoto, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kandziora, J | 1 |
| Edmands, S; Yancey, PH | 1 |
| Nakanishi, T; Sugita, M; Uyama, O | 1 |
| Bornemann, A; Guder, WG; Schmolke, M | 1 |
| Burg, MB; Garcia-Perez, A | 3 |
| Burg, MB; Garcia-Perez, A; Moriyama, T; Olson, AD | 1 |
| Balaban, RS; Wolff, SD | 1 |
| Burg, MB; Garcia-Perez, A; Moriyama, T | 1 |
| Beck, FX; Guder, WG; Schmolke, M | 2 |
| Burg, MB; Nakanishi, T; Turner, RJ | 1 |
| Balaban, RS; James, SL; Stanton, TS; Wolff, SD | 1 |
| Gullans, SR; Heilig, CW; Stromski, ME | 1 |
| Goldstein, L | 1 |
| Burg, MB; Yancey, PH | 1 |
| Chambers, ST; Kunin, CM | 1 |
| Bancons, J; Dubarry, JJ; Gasnier, P; Quinton, A | 1 |
| Abbou, R; Dubrisay, J; Mahoudeau, D; Volteau, M | 1 |
| Burg, MB | 2 |
| Bedford, JJ; Leader, JP; Smiley, M | 1 |
| Bason, LM; Chambers, ST; Hayman, CM; Lever, M; Robson, RA; Sizeland, PC | 1 |
| Bason, LM; Chambers, ST; Lever, M; Robson, RA; Sizeland, PC | 2 |
| Nakahama, H; Nakanishi, T; Sugita, M; Takamitsu, Y | 1 |
| Nakahama, H; Nakanishi, T; Sugita, M; Takamitsu, Y; Uyama, O | 1 |
| García-Pérez, A | 1 |
| Burg, MB; Ferraris, JD; García-Pérez, A; Peters, EM; Williams, CK | 1 |
| Wieckowski, MR; Zabłocki, K | 1 |
| Guder, WG; Keiditsch, E; Schilling, A; Schmolke, M | 1 |
| Foote, RH; Liu, Z | 1 |
| Nakanishi, T; Takamitsu, Y | 1 |
| Burg, MB; Kwon, ED; Peters, EM | 1 |
| Handler, JS; Kwon, HM | 2 |
| Burkovski, A; Krämer, R; Peter, H | 1 |
| Lindquist, S; Singer, MA | 1 |
| Busch, GL; Lang, F; Matskevitch, J; Waldegger, S | 1 |
| Kinne, RK | 1 |
| Beck, FX; Burger-Kentischer, A; Fraek, ML; März, J; Müller, E; Thurau, K | 1 |
| Beck, FX; Dörge, A; Fraek, ML; Müller, E; Thurau, K | 1 |
| Cape, SP; Carpenter, JF; Chi, E; Kim, YS; Manning, MC; Raffen, R; Randolph, TW; Solomon, A; Stevens, FJ; Wilkins-Stevens, P | 1 |
| Dan, M; Ishizaki, A; Kimura, H; Matsusaki, H; Sashihara, T; Sonomoto, K | 1 |
| Fiedler, GM; Grunewald, RW; Jehle, PM; Oppermann, M; Schettler, V; Schuettert, JB | 1 |
| Farnum, CE; Lee, R; O'Hara, K; Urban, JP | 1 |
| Chen, TH; Murata, N | 1 |
| Fogel, JM; Moeckel, GW; Sadrzadeh, SM; Shadman, R | 1 |
| Breyer, MD; Fogo, AB; Hao, CM; Moeckel, GW; Pozzi, A; Zhang, L | 1 |
| Fischer, H; Gullans, SR; Howard, M; Roux, J; Santos, BC; Welch, WJ; Yancey, PH | 1 |
| Banerjee, R; Bhattacharyya, A; Lahiri, S; Mandal, AK; Roy, S; Samaddar, S | 1 |
| Krämer, R; Morbach, S; Steger, R; Weinand, M | 1 |
| Fukui, K; Kurokawa, Y; Sandee, D; Takagi, M; Tungpradabkul, S | 1 |
| Yamauchi, A | 1 |
| Brodelius, PE; Olsson, ME; Picaud, S | 1 |
| Beck, FX; Neuhofer, W | 1 |
| Atkinson, W; Chambers, ST; George, PM; Lever, M; Sizeland, PC | 1 |
| Rau, DC; Stanley, C | 1 |
| Bayley, M; Holmstrup, M; Malmendal, A; Overgaard, J; Petersen, CR | 1 |
| Jackson-Atogi, R; Rösgen, J; Sinha, PK | 1 |
| Myers, JK; Silvers, TR | 1 |
| Singh, LR; Warepam, M | 1 |
| Choudhary, S; Hosur, RV; Kishore, N | 1 |
| Du, H; Massiah, MA; Wright, KM | 1 |
| Ahmad, F; Dar, MA; Hassan, MI; Islam, A | 2 |
| Al-Attar, R; Storey, KB; Zhang, Y | 1 |
| Cho, M; Kossowska, D; Kwak, K | 1 |
| An, L; Chen, J; Liu, Z; Song, X; Wang, M; Yao, L | 1 |
| Baruah, I; Borgohain, G | 1 |
16 review(s) available for sorbitol and betaine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Role of organic osmolytes in adaptation of renal cells to high osmolality.
Topics: Aldehyde Reductase; Animals; Betaine; Choline; Glycerylphosphorylcholine; Kidney; Sodium Chloride; Sorbitol; Urea; Water-Electrolyte Balance | 1991 |
Renal medullary organic osmolytes.
Topics: Animals; Betaine; Glycerylphosphorylcholine; Humans; Inositol; Kidney Medulla; Osmolar Concentration; Sorbitol; Taurine | 1991 |
Regulation of the predominant renal medullary organic solutes in vivo.
Topics: Animals; Betaine; Biological Transport; Diuresis; Glycerylphosphorylcholine; Inositol; Kidney; Kidney Medulla; Osmosis; Sorbitol; Tissue Distribution | 1990 |
Importance of organic osmolytes for osmoregulation by renal medullary cells.
Topics: Alcohols; Amino Acids; Animals; Betaine; Diuresis; Glycerylphosphorylcholine; Humans; Inositol; Kidney Medulla; Methylamines; Sorbitol; Water-Electrolyte Balance | 1990 |
Molecular basis of osmotic regulation.
Topics: Aldehyde Reductase; Animals; Betaine; Biological Transport; Carrier Proteins; Gene Expression; Glycerylphosphorylcholine; Humans; Inositol; Kidney; Kidney Medulla; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Models, Structural; Osmolar Concentration; Protein Structure, Secondary; Sodium Chloride; Sorbitol; Taurine; Urea; Water-Electrolyte Balance | 1995 |
Molecular basis for osmoregulation of organic osmolytes in renal medullary cells.
Topics: Animals; Betaine; Cell Division; Cell Survival; Cells, Cultured; Inositol; Kidney Medulla; Phosphatidylcholines; Sorbitol; Taurine; Water-Electrolyte Balance | 1994 |
Organic osmolytes in the kidney.
Topics: Aldehyde Reductase; Animals; Betaine; Cells, Cultured; Diuresis; Glycerylphosphorylcholine; Humans; Inositol; Kidney; Kidney Concentrating Ability; Osmolar Concentration; Sorbitol; Taurine | 1993 |
[Osmolytes and osmoregulation in renal cells].
Topics: Adaptation, Physiological; Animals; Betaine; Cells, Cultured; Glycerylphosphorylcholine; Inositol; Kidney; Osmolar Concentration; Sorbitol; Taurine; Water-Electrolyte Balance | 1996 |
Kidney cell survival in high tonicity.
Topics: Animals; Betaine; Biological Transport, Active; Cell Survival; Glycerylphosphorylcholine; Humans; Inositol; Kidney Concentrating Ability; Kidney Medulla; Signal Transduction; Sorbitol; Taurine; Water-Electrolyte Balance | 1997 |
Introduction to cell volume regulatory mechanisms.
Topics: Amino Acids; Animals; Betaine; Cell Size; Glycerylphosphorylcholine; Humans; Inositol; Ion Channels; Ion Transport; Membrane Potentials; Osmosis; Osmotic Pressure; Sorbitol; Taurine | 1998 |
Mechanisms of osmolyte release.
Topics: Animals; Betaine; Calcium Signaling; Cell Membrane Permeability; Cell Polarity; Diabetes Mellitus; Glycerylphosphorylcholine; Humans; Hypotonic Solutions; Inositol; Ion Channel Gating; Ion Channels; Ion Transport; Kidney Tubules, Collecting; Loop of Henle; Osmotic Pressure; Rabbits; Rats; Sorbitol; Taurine | 1998 |
Cellular osmoregulation in kidney medulla.
Topics: Amino Acids; Animals; Betaine; Diuresis; Glycerylphosphorylcholine; Heat-Shock Proteins; Humans; Inositol; Kidney Medulla; Mammals; Natriuresis; Osmotic Pressure; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Sorbitol; Stress, Physiological; Urea; Water-Electrolyte Balance | 1998 |
Enhancement of tolerance of abiotic stress by metabolic engineering of betaines and other compatible solutes.
Topics: Adaptation, Physiological; Betaine; Choline; Fructans; Genetic Engineering; Glycine; Mannitol; Oxidative Stress; Plants; Plants, Genetically Modified; Proline; Sorbitol; Stress, Mechanical; Trehalose | 2002 |
[Molecular mechanism in biological transport in the kidney: Osmolyte transporter].
Topics: Animals; Betaine; Biological Transport; Carrier Proteins; GABA Plasma Membrane Transport Proteins; Gene Expression Regulation; Glycerylphosphorylcholine; Heat-Shock Proteins; Humans; Inositol; Kidney Medulla; Membrane Proteins; Osmolar Concentration; Sorbitol; Symporters; Taurine; Transcription Factors; Transcription, Genetic | 2006 |
Cell volume regulation in the renal papilla.
Topics: Adaptation, Physiological; Animals; Betaine; Carrier Proteins; Cell Size; Cell Survival; Cells, Cultured; Extracellular Space; GABA Plasma Membrane Transport Proteins; Inositol; Kidney Medulla; Kidney Tubules, Collecting; Osmotic Pressure; Rats; Sorbitol; Water-Electrolyte Balance | 2006 |
1 trial(s) available for sorbitol and betaine
| Article | Year |
|---|---|
Abnormal glycine betaine content of the blood and urine of diabetic and renal patients.
Topics: Adult; Albuminuria; Betaine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Female; Glycine; Hemoglobins; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Liver Diseases; Male; Middle Aged; Sex Characteristics; Sorbitol | 1994 |
58 other study(ies) available for sorbitol and betaine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Cellular zwitterionic metabolite analogs simultaneously enhance reaction rate, thermostability, salt tolerance, and substrate specificity of α-glucosidase.
Topics: alpha-Glucosidases; Betaine; Enzyme Stability; Ions; Kinetics; Models, Molecular; Protein Conformation; Saccharomyces cerevisiae; Salt Tolerance; Substrate Specificity; Temperature | 2011 |
[Therapeutic experience with the lipotropic hepatic drug Flacar in the internal medicine practice].
Topics: Adult; Aged; Betaine; Drug Combinations; Drug Evaluation; Female; Humans; Internal Medicine; Liver Diseases; Male; Middle Aged; Professional Practice; Sorbitol | 1976 |
Effects on rat renal osmolytes of extended treatment with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Betaine; Body Weight; Imidazoles; Imidazolidines; Kidney; Male; Osmolar Concentration; Rats; Rats, Wistar; Sorbitol; Time Factors; Urine | 1992 |
Osmotically regulated taurine content in rat renal inner medulla.
Topics: Amino Acids; Animals; Aspartic Acid; Betaine; Glycerylphosphorylcholine; Hypotonic Solutions; Inositol; Kidney Medulla; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic; Sodium Chloride; Sorbitol; Taurine; Water-Electrolyte Balance | 1991 |
Distribution and regulation of organic osmolytes along the nephron.
Topics: Animals; Betaine; Glycerylphosphorylcholine; In Vitro Techniques; Inositol; Nephrons; Osmolar Concentration; Rats; Rats, Inbred Strains; Sorbitol | 1991 |
Intracellular betaine substitutes for sorbitol in protecting renal medullary cells from hypertonicity.
Topics: Aldehyde Reductase; Animals; Betaine; Cell Division; Cell Line; Cell Survival; Clone Cells; Glycerylphosphorylcholine; Inositol; Kidney Medulla; Naphthalenes; Rabbits; Saline Solution, Hypertonic; Sorbitol | 1991 |
Factors affecting the ratio of different organic osmolytes in renal medullary cells.
Topics: Animals; Betaine; Cell Line; Culture Media; Glycerylphosphorylcholine; Hypertonic Solutions; Inositol; Kidney Medulla; Osmolar Concentration; Sodium Chloride; Sorbitol; Urea | 1990 |
Regulation and localization of organic osmolytes in mammalian kidney.
Topics: Animals; Betaine; Diabetes Insipidus; Diabetes Mellitus, Experimental; Glycerylphosphorylcholine; Inositol; Kidney; Methylamines; Polymers; Rats; Rats, Brattleboro; Sorbitol; Water-Electrolyte Balance | 1990 |
Osmoregulation of betaine transport in mammalian renal medullary cells.
Topics: Animals; Betaine; Biological Transport; Cell Line; Glycerylphosphorylcholine; Hypertonic Solutions; Inositol; Kidney Medulla; Osmolar Concentration; Sodium Chloride; Sorbitol; Water-Electrolyte Balance | 1990 |
Acute regulation of the predominant organic solutes of the rabbit renal inner medulla.
Topics: Animals; Betaine; Diuresis; Furosemide; Glycerylphosphorylcholine; Homeostasis; Inositol; Kidney Medulla; Magnetic Resonance Spectroscopy; Male; Mannitol; Phosphorus; Rabbits; Sodium; Sorbitol; Urea; Vasopressins | 1989 |
Methylamine and polyol responses to salt loading in renal inner medulla.
Topics: Animals; Betaine; Hypernatremia; Inositol; Kidney Medulla; Male; Methylamines; Rats; Rats, Inbred Strains; Reference Values; Sodium; Sodium Chloride; Sorbitol; Sugar Alcohols | 1989 |
Organic solute profiles and transport in the rat renal medulla.
Topics: Animals; Betaine; Biological Transport; Diabetes Mellitus, Experimental; Glycerylphosphorylcholine; In Vitro Techniques; Inositol; Kidney Medulla; Male; Polyethylene Glycols; Rats; Rats, Inbred Strains; Sorbitol | 1989 |
Distribution of major organic osmolytes in rabbit kidneys in diuresis and antidiuresis.
Topics: Animals; Betaine; Diuresis; Glycerylphosphorylcholine; Inositol; Kidney; Kidney Cortex; Kidney Medulla; Methylamines; Osmolar Concentration; Rabbits; Sorbitol | 1989 |
Osmoprotective activity for Escherichia coli in mammalian renal inner medulla and urine. Correlation of glycine and proline betaines and sorbitol with response to osmotic loads.
Topics: Animals; Betaine; Cattle; Diuresis; Dogs; Escherichia coli; Fasting; Kidney Medulla; Male; Osmolar Concentration; Proline; Rabbits; Rats; Sheep; Sodium Chloride; Sorbitol; Swine; Urine; Water Deprivation | 1987 |
[Steatrope in digestive pathology].
Topics: Adult; Aged; Betaine; Digestion; Female; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Lipotropic Agents; Male; Middle Aged; Sorbitol | 1970 |
[Significance of combined arginine-betaine-sorbitol therapy in the treatment of metabolic liver diseases].
Topics: Adult; Aged; Arginine; Betaine; Humans; Liver Diseases; Middle Aged; Quaternary Ammonium Compounds; Sorbitol | 1965 |
Organic osmolytes in the kidney of domesticated red deer, Cervus elaphus.
Topics: Alanine; Amino Acids; Animals; Animals, Domestic; Betaine; Deer; Glycerylphosphorylcholine; Glycine; Inositol; Kidney; Kidney Cortex; Kidney Medulla; Osmolar Concentration; Osmosis; Sorbitol; Taurine; Tissue Distribution | 1995 |
Short-term response of nonurea organic osmolytes in human kidney to a water load and water deprivation.
Topics: Adult; Betaine; Deamino Arginine Vasopressin; Diuresis; Drinking; Humans; Kidney; Male; Sorbitol; Time Factors; Water Deprivation; Water-Electrolyte Balance | 1995 |
Impairment of renal medullary osmolyte accumulation in potassium-depleted rats.
Topics: Animals; Betaine; Diuresis; Glycerylphosphorylcholine; Inositol; Kidney Concentrating Ability; Kidney Medulla; Male; Osmosis; Potassium Deficiency; Rats; Rats, Wistar; Sodium; Sorbitol; Taurine; Water Deprivation | 1994 |
Organic osmolytes in human and other mammalian kidneys.
Topics: Animals; Betaine; Dogs; Glycerylphosphorylcholine; Humans; Inositol; Kidney Medulla; Male; Osmosis; Rabbits; Sorbitol; Species Specificity; Swine | 1993 |
Determinants of relative amounts of medullary organic osmolytes: effects of NaCl and urea differ.
Topics: Animals; Betaine; Blood; Body Water; Glycerylphosphorylcholine; Inositol; Kidney Medulla; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar; Sodium; Sodium Chloride; Sorbitol; Taurine; Urea | 1993 |
Betaine transporter cDNA cloning and effect of osmolytes on its mRNA induction.
Topics: Amino Acid Sequence; Animals; Base Sequence; Betaine; Carrier Proteins; Cell Line; Cloning, Molecular; DNA, Complementary; GABA Plasma Membrane Transport Proteins; Hypertonic Solutions; Inositol; Kidney Medulla; Molecular Sequence Data; Rabbits; RNA, Messenger; Sequence Homology; Sorbitol; Water-Electrolyte Balance | 1996 |
Intrarenal distribution of organic osmolytes in human kidney.
Topics: Animals; Betaine; Chromatography, High Pressure Liquid; Glycerylphosphorylcholine; Humans; Inositol; Kidney; Kidney Medulla; Rats; Rats, Sprague-Dawley; Sorbitol; Tissue Distribution; Water-Electrolyte Balance | 1996 |
Sodium chloride, osmolyte, and osmolarity effects on blastocyst formation in bovine embryos produced by in vitro fertilization (IVF) and cultured in simple serum-free media.
Topics: Animals; Betaine; Blastocyst; Cattle; Culture Media, Serum-Free; Embryonic and Fetal Development; Fertilization in Vitro; Inositol; Osmolar Concentration; Sodium Chloride; Sorbitol; Zygote | 1996 |
Renal concentrating defect and organic osmolytes. Paradoxical changes of renal medullary taurine contents in potassium-depleted rats.
Topics: Animals; Betaine; Dehydration; Glycerylphosphorylcholine; Inositol; Kidney Medulla; Male; Potassium; Potassium Deficiency; Rats; Rats, Wistar; Reference Values; Sodium; Sorbitol; Taurine; Urea | 1996 |
Glycerophosphocholine and betaine counteract the effect of urea on pyruvate kinase.
Topics: Animals; Betaine; Glycerylphosphorylcholine; Inositol; Kidney Medulla; Pyruvate Kinase; Sorbitol; Taurine; Urea | 1996 |
Osmo-sensing by N- and C-terminal extensions of the glycine betaine uptake system BetP of Corynebacterium glutamicum.
Topics: Amino Acids, Diamino; Anesthetics, Local; Bacterial Proteins; Betaine; Biological Transport; Carrier Proteins; Cations, Monovalent; Corynebacterium; Gene Expression Regulation, Bacterial; Models, Molecular; Mutation; Osmolar Concentration; Osmotic Pressure; Peptide Fragments; Protein Structure, Secondary; Recombinant Proteins; Signal Transduction; Sodium; Sodium Chloride; Sorbitol; Symporters; Tetracaine | 1998 |
Multiple effects of trehalose on protein folding in vitro and in vivo.
Topics: Animals; Betaine; Coleoptera; Fluorescence Polarization; Fungal Proteins; Genes, Reporter; Glucose; Glycerol; Heat-Shock Proteins; Luciferases; Maltose; Mannitol; Molecular Chaperones; Proline; Protein Folding; Sorbitol; Sucrose; Temperature; Trehalose; Yeasts | 1998 |
Hypertonicity-induced accumulation of organic osmolytes in papillary interstitial cells.
Topics: Aldehyde Reductase; Amino Acids; Animals; Betaine; Blotting, Northern; Carrier Proteins; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Fibroblasts; GABA Plasma Membrane Transport Proteins; Glycerylphosphorylcholine; Heat-Shock Proteins; Hypertonic Solutions; In Situ Hybridization; Inositol; Kidney Medulla; Kidney Tubules, Collecting; L-Iditol 2-Dehydrogenase; Male; Membrane Proteins; Osmolar Concentration; Rats; Rats, Wistar; RNA, Messenger; Sorbitol; Symporters | 1999 |
Inner-medullary organic osmolytes and inorganic electrolytes in K depletion.
Topics: Amino Acids; Animals; Betaine; Chlorides; Chromatography, High Pressure Liquid; Electrolytes; Electron Probe Microanalysis; Glycerylphosphorylcholine; Inositol; Kidney Concentrating Ability; Kidney Medulla; Kidney Tubules, Collecting; Male; Potassium, Dietary; Rats; Rats, Wistar; Sodium, Dietary; Sorbitol; Urea; Water-Electrolyte Balance | 2000 |
Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains.
Topics: Amyloid; Amyloidosis; Betaine; Chromatography, High Pressure Liquid; Guanidine; Humans; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Kidney; Kinetics; Lymph Nodes; Sorbitol; Thermodynamics; Urea | 2001 |
Cell and molecular biology of organic osmolyte accumulation in hypertonic renal cells.
Topics: Animals; Betaine; Carrier Proteins; Heat-Shock Proteins; Humans; Hypertonic Solutions; Inositol; Kidney Medulla; Membrane Proteins; Osmosis; Signal Transduction; Sorbitol; Symporters; Trans-Activators; Transcription Factors; Transcriptional Activation | 2001 |
The effect of osmotic stress on the production of nukacin ISK-1 from Staphylococcus warneri ISK-1.
Topics: Bacterial Proteins; Bacteriocins; Betaine; Gene Expression Regulation, Bacterial; Osmolar Concentration; Osmotic Pressure; Sodium Chloride; Sorbitol; Staphylococcus; Transcription, Genetic | 2001 |
Polarized function of thick ascending limbs of Henle cells in osmoregulation.
Topics: Animals; Betaine; Cell Line; Cell Membrane; Cell Polarity; Choline; Glycerylphosphorylcholine; Inositol; Intracellular Membranes; Loop of Henle; Rabbits; Sorbitol; Tissue Distribution; Water-Electrolyte Balance | 2001 |
Volume increase in growth plate chondrocytes during hypertrophy: the contribution of organic osmolytes.
Topics: Amino Acids; Animals; Betaine; Cattle; Cell Differentiation; Cell Size; Chondrocytes; Growth Plate; Hypertrophy; Inositol; Osteogenesis; Ribs; Sorbitol; Water-Electrolyte Balance | 2002 |
Organic osmolytes betaine, sorbitol and inositol are potent inhibitors of erythrocyte membrane ATPases.
Topics: Adenosine Triphosphatases; Betaine; Enzyme Inhibitors; Erythrocyte Membrane; Inositol; Osmolar Concentration; Sorbitol; Urea | 2002 |
COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress.
Topics: Adaptation, Physiological; Aldehyde Reductase; Animals; Apoptosis; Betaine; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dehydration; DNA Fragmentation; Gene Expression; Heat-Shock Proteins; Hypertonic Solutions; In Situ Nick-End Labeling; Inositol; Isoenzymes; Kidney Medulla; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sorbitol; Symporters; Tritium | 2003 |
Mammalian osmolytes and S-nitrosoglutathione promote Delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) protein maturation and function.
Topics: 3T3 Cells; Animals; Betaine; Cells, Cultured; Cystic Fibrosis Transmembrane Conductance Regulator; Inositol; Kidney Tubules, Collecting; Mammals; Mice; Nitric Oxide Donors; Osmolar Concentration; Patch-Clamp Techniques; S-Nitrosoglutathione; Sequence Deletion; Sorbitol; Stress, Mechanical; Taurine; Transfection | 2003 |
Glutamate counteracts the denaturing effect of urea through its effect on the denatured state.
Topics: Amino Acyl-tRNA Synthetases; Animals; Betaine; Carbonic Anhydrases; Cattle; Dose-Response Relationship, Drug; Escherichia coli; Glutamates; Glutamic Acid; Inositol; Kinetics; Methylamines; Oxidants; Potassium Chloride; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Sorbitol; Spectrophotometry; Temperature; Thermodynamics; Time Factors; Trypsin; Tubulin; Urea | 2003 |
LcoP, an osmoregulated betaine/ectoine uptake system from Corynebacterium glutamicum.
Topics: Amino Acid Sequence; Amino Acids, Diamino; Bacterial Proteins; Betaine; Biological Transport; Corynebacterium; Kinetics; Molecular Sequence Data; Osmolar Concentration; Proline; RNA; Sodium Chloride; Sorbitol | 2004 |
Combination of Dsb coexpression and an addition of sorbitol markedly enhanced soluble expression of single-chain Fv in Escherichia coli.
Topics: Antibodies, Monoclonal; Bacterial Proteins; Base Sequence; Betaine; Binding, Competitive; Cell Proliferation; Escherichia coli; Genetic Vectors; Growth Inhibitors; Immunoglobulin Fragments; Membrane Proteins; Molecular Sequence Data; Plasmids; Protein Sorting Signals; Single-Chain Antibodies; Sodium Chloride; Solubility; Sorbitol; Sucrose | 2005 |
Improved conditions for production of recombinant plant sesquiterpene synthases in Escherichia coli.
Topics: Alkyl and Aryl Transferases; Artemisia annua; Betaine; Enzyme Induction; Escherichia coli; Isopropyl Thiogalactoside; Molecular Biology; Osmotic Pressure; Protein Folding; Recombinant Fusion Proteins; Sorbitol; Zingiber officinale | 2007 |
Inter- and intra-individual variations in normal urinary glycine betaine excretion.
Topics: Adult; Age Factors; Betaine; Chromatography, High Pressure Liquid; Creatinine; Humans; Male; Sorbitol; Time Factors | 2007 |
Measuring the interaction of urea and protein-stabilizing osmolytes with the nonpolar surface of hydroxypropylcellulose.
Topics: Algorithms; Betaine; Cellulose; Glycerol; Hydrophobic and Hydrophilic Interactions; Methylamines; Models, Chemical; Organic Chemicals; Osmotic Pressure; Proteins; Scattering, Radiation; Sorbitol; Temperature; Thermodynamics; Urea; X-Rays | 2008 |
Slow desiccation improves dehydration tolerance and accumulation of compatible osmolytes in earthworm cocoons (Dendrobaena octaedra Savigny).
Topics: Acclimatization; Alanine; Analysis of Variance; Animals; Betaine; Dehydration; Denmark; Desiccation; Embryo, Nonmammalian; Glucose; Magnetic Resonance Spectroscopy; Mannitol; Oligochaeta; Osmotic Pressure; Ovum; Sorbitol; Survival Analysis | 2008 |
Distinctive solvation patterns make renal osmolytes diverse.
Topics: Betaine; Inositol; Kidney; Models, Molecular; Molecular Conformation; Osmosis; Phosphorylcholine; Solubility; Solvents; Sorbitol; Taurine | 2013 |
Osmolyte effects on the self-association of concanavalin A: testing theoretical models.
Topics: Betaine; Circular Dichroism; Concanavalin A; Dimerization; Hydrogen-Ion Concentration; Indicators and Reagents; Methylamines; Models, Molecular; Osmolar Concentration; Proline; Protein Interaction Domains and Motifs; Protein Stability; Sarcosine; Secondary Metabolism; Sorbitol; Sucrose; Thermodynamics; Titrimetry; Trehalose; Urea | 2013 |
Osmolyte mixtures have different effects than individual osmolytes on protein folding and functional activity.
Topics: Betaine; Cytosine Nucleotides; Enzyme Stability; Hydrolysis; Methylamines; Osmolar Concentration; Protein Folding; Protein Refolding; Ribonuclease, Pancreatic; Sarcosine; Sorbitol; Thermodynamics | 2015 |
Inhibition of insulin fibrillation by osmolytes: Mechanistic insights.
Topics: Amyloid; Betaine; Calorimetry; Insulin; Kinetics; Models, Biological; Osmolar Concentration; Proline; Protein Aggregation, Pathological; Protein Binding; Sorbitol | 2015 |
Obtaining Soluble Folded Proteins from Inclusion Bodies Using Sarkosyl, Triton X-100, and CHAPS: Application to LB and M9 Minimal Media.
Topics: Betaine; Cholic Acids; Escherichia coli; Glutathione Transferase; Histidine; Inclusion Bodies; Octoxynol; Protein Engineering; Protein Folding; Recombinant Fusion Proteins; Recombinant Proteins; Sarcosine; Solubility; Sorbitol | 2016 |
Effect of mammalian kidney osmolytes on the folding pathway of sheep serum albumin.
Topics: Animals; Betaine; Guanidine; Inositol; Kidney; Osmosis; Protein Denaturation; Protein Folding; Protein Stability; Serum Albumin; Sheep; Sorbitol; Thermodynamics; Urea | 2017 |
TonEBP/NFAT5 regulates downstream osmoregulatory proteins during freeze-thaw stress in the wood frog.
Topics: Adaptation, Physiological; Aldehyde Reductase; Animals; Betaine; Carrier Proteins; Cold Temperature; Crystallization; Dehydration; Freezing; GABA Plasma Membrane Transport Proteins; Gene Expression Regulation; Heat-Shock Proteins; Inositol; Kidney; Liver; Muscle, Skeletal; NFATC Transcription Factors; Osmoregulation; Osmotic Pressure; Ranidae; Sorbitol; Symporters; Transcriptional Activation; Up-Regulation | 2017 |
Counteraction of the deleterious effects of urea on structure and stability of mammalian kidney proteins by osmolytes.
Topics: Animals; Betaine; Guanidine; Inositol; Kidney; Mammals; Osmolar Concentration; Protein Stability; Proteins; Sheep; Sorbitol; Urea | 2018 |
Do Osmolytes Impact the Structure and Dynamics of Myoglobin?
Topics: Betaine; Circular Dichroism; Inositol; Myoglobin; Osmosis; Protein Stability; Sorbitol; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Taurine; Temperature; Trehalose | 2018 |
Osmolytes Can Destabilize Proteins in Cells by Modulating Electrostatics and Quinary Interactions.
Topics: Bacterial Proteins; Betaine; Escherichia coli; Glycerol; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Protein Folding; Protein Stability; Proteins; Sorbitol; Static Electricity; Taurine; Thermodynamics | 2021 |
Temperature dependent molecular dynamics simulation study to understand the stabilizing effect of NADES on the protein β-Lactoglobulin.
Topics: Betaine; Lactoglobulins; Molecular Dynamics Simulation; Solvents; Sorbitol; Temperature; Water | 2023 |