sorbitan-monooleate and citral

Citral-loaded solid lipid nanoparticles (citral-SLNs) were prepared via a high-pressure homogenization method, using glyceryl monostearate (GMS) as the solid lipid and a mixture of Tween 80 (T-80) and Span 80 (S-80) at a weight ratio of 1:1 as the surfactant. The microstructure and properties of the citral-SLNs were characterized by dynamic light scattering (DLS), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and thermal gravimetric analysis (TGA). The chemical stability of citral in the citral-SLNs was analyzed by solid-phase microextraction gas chromatography (SPME-GC). The GC results showed that 67.0% of the citral remained in the citral-SLN suspensions after 12 days, while only 8.22% remained in the control. Therefore, the encapsulation of citral in the solid lipid can enhance its stability in acidic surroundings.

Topics: Acyclic Monoterpenes; Adult; Beverages; Calorimetry, Differential Scanning; Chromatography, Gas; Female; Food Additives; Glycerides; Hexoses; Humans; Male; Microscopy, Electron, Scanning; Monoterpenes; Nanoparticles; Polysorbates; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Thermogravimetry; X-Ray Diffraction