sorafenib has been researched along with zileuton in 3 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (zileuton) | Trials (zileuton) | Recent Studies (post-2010) (zileuton) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 551 | 64 | 193 |
| Protein | Taxonomy | sorafenib (IC50) | zileuton (IC50) |
|---|---|---|---|
| Prostaglandin E synthase | Homo sapiens (human) | 0.6 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.4782 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.9656 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | 0.4 | |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | 0.58 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.591 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Mus musculus (house mouse) | 0.19 | |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | 0.42 | |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | 0.42 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 0.42 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for sorafenib and zileuton
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for sorafenib and zileuton
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |