Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and y 27632

sorafenib has been researched along with y 27632 in 2 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010) (y 27632)
6,5207305,2511,9243891

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)y 27632 (IC50)
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)6
Chain I, cAMP-dependent protein kinase inhibitor alphasynthetic construct6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)6
Chain I, cAMP-dependent protein kinase inhibitor alphasynthetic construct6
Rho-associated protein kinase 2Homo sapiens (human)0.1942
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)8.3
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)6.1
C-C motif chemokine 2Homo sapiens (human)2.6303
Rho-associated protein kinase 1Homo sapiens (human)0.3713
Serine/threonine-protein kinase N2Homo sapiens (human)0.6
Rho-associated protein kinase 2Bos taurus (cattle)6.1
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)0.8

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

2 other study(ies) available for sorafenib and y 27632

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013