Page last updated: 2024-09-05

sorafenib and vincaleukoblastine

sorafenib has been researched along with vincaleukoblastine in 4 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(vincaleukoblastine)
Trials
(vincaleukoblastine)
Recent Studies (post-2010) (vincaleukoblastine)
6,5207305,25169064

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)vincaleukoblastine (IC50)
Tubulin beta-4A chainHomo sapiens (human)0.74
Tubulin beta chainHomo sapiens (human)0.74
Tubulin alpha-3C chainHomo sapiens (human)0.74
Proteasome subunit beta type-1Homo sapiens (human)4.28
ATP-dependent translocase ABCB1Mus musculus (house mouse)8.8
Proteasome subunit beta type-5Homo sapiens (human)4.58
Proteasome subunit beta type-2Homo sapiens (human)4.9
Tubulin alpha-1B chainHomo sapiens (human)0.74
Tubulin alpha-4A chainHomo sapiens (human)0.74
Tubulin beta-4B chainHomo sapiens (human)0.74
Tubulin beta-3 chainHomo sapiens (human)0.74
Tubulin beta-2A chainHomo sapiens (human)0.74
Tubulin beta-8 chainHomo sapiens (human)0.74
Tubulin alpha-3E chainHomo sapiens (human)0.74
Tubulin alpha-1A chainHomo sapiens (human)0.74
Tubulin alpha-1C chainHomo sapiens (human)0.74
Tubulin beta-6 chainHomo sapiens (human)0.74
Tubulin beta-2B chainHomo sapiens (human)0.74
Tubulin beta-1 chainHomo sapiens (human)0.74

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aboul-Enein, HY; Ali, I; Lone, MN1
Chen, TL; Hou, MH; Jain, V; Kuppusamy, R; Lee, TC; Lin, YW; Patel, AS; Su, TL1

Reviews

2 review(s) available for sorafenib and vincaleukoblastine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Imidazoles as potential anticancer agents.
    MedChemComm, 2017, Sep-01, Volume: 8, Issue:9

    Topics:

2017

Other Studies

2 other study(ies) available for sorafenib and vincaleukoblastine

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Discovery of Oral Anticancer 1,2-Bis(hydroxymethyl)benzo[
    Journal of medicinal chemistry, 2021, 09-09, Volume: 64, Issue:17

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasms, Squamous Cell; Neovascularization, Pathologic; Phthalazines; Small Cell Lung Carcinoma; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2021