Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and ursolic acid

sorafenib has been researched along with ursolic acid in 3 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(ursolic acid)		Trials
(ursolic acid)		Recent Studies (post-2010) (ursolic acid)
6,5207305,2511,577101,083

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)ursolic acid (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)4
Glycogen phosphorylase, muscle formOryctolagus cuniculus (rabbit)8.9708
Basic phospholipase A2 1Naja melanoleuca (forest cobra)2.9
DNA polymerase betaRattus norvegicus (Norway rat)6.65
Neutrophil elastaseHomo sapiens (human)0.416
Receptor-type tyrosine-protein phosphatase FHomo sapiens (human)3.8
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)4.1433
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)3.8872
Liver carboxylesterase 1Homo sapiens (human)0.1
Low molecular weight phosphotyrosine protein phosphataseHomo sapiens (human)7.2
Corticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiens (human)1.9
Delta-type opioid receptorMus musculus (house mouse)3.6
Nuclear receptor ROR-gammaHomo sapiens (human)3.5333
Basic phospholipase A2 PLA-AProtobothrops flavoviridis2.5
Transcription factor p65Homo sapiens (human)0.031
Acidic phospholipase A2 EC-IEchis carinatus (saw-scaled viper)2.3
Ubiquitin carboxyl-terminal hydrolase 7Homo sapiens (human)7
Sentrin-specific protease 1Homo sapiens (human)1.2932
Protease Human immunodeficiency virus 18

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Cheng, JC; Hung, HY; Hwang, TL; Kuo, DH; Kuo, PC; Lee, EJ; Nian, CW; Tai, SH; Wu, TS1
Fan, L; Jiang, K; Li, T; Shao, J; Zhao, R; Zheng, G1
Huang, X; Law, BYK; Li, H; Li, W; Liu, Y; Luo, Z; Yu, Y; Zheng, Y1

Other Studies

3 other study(ies) available for sorafenib and ursolic acid

ArticleYear
Chemical Constituents and Anti-inflammatory Principles from the Fruits of Forsythia suspensa.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: Anti-Inflammatory Agents; Diterpenes; Forsythia; Fruit; Humans; Lignans; Molecular Structure; Neutrophils; Pancreatic Elastase; Superoxides; Taiwan

2017
Simultaneous inhibition of growth and metastasis of hepatocellular carcinoma by co-delivery of ursolic acid and sorafenib using lactobionic acid modified and pH-sensitive chitosan-conjugated mesoporous silica nanocomplex.
    Biomaterials, 2017, Volume: 143

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chitosan; Delayed-Action Preparations; Disaccharides; Drug Synergism; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Lung Neoplasms; Male; Mice; Nanoparticles; Niacinamide; Phenylurea Compounds; Porosity; Rats; Silicon Dioxide; Sorafenib; Triterpenes; Ursolic Acid

2017
Ursolic acid enhances the antitumor effects of sorafenib associated with Mcl-1-related apoptosis and SLC7A11-dependent ferroptosis in human cancer.
    Pharmacological research, 2022, Volume: 182

    Topics: Amino Acid Transport System y+; Apoptosis; Cell Line, Tumor; Ferroptosis; Humans; Neoplasms; Sorafenib; Triterpenes; Ursolic Acid

2022