Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and triptolide

sorafenib has been researched along with triptolide in 4 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(triptolide)		Trials
(triptolide)		Recent Studies (post-2010) (triptolide)
6,5207305,2511,1586820

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)triptolide (IC50)
Prostaglandin G/H synthase 2Homo sapiens (human)0.04
Proteinase-activated receptor 2Homo sapiens (human)0.0185

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Alsaied, OA; Banerjee, S; Chugh, R; Jensen, EH; Krosch, TC; Saluja, A; Sangwan, V; Vickers, SM1
Lu, YJ; Ma, LM; Tian, WW; Wang, T; Wang, X1
Gong, C; Han, L; Li, Z; Wang, R; Yang, G; Yuan, Y1

Other Studies

4 other study(ies) available for sorafenib and triptolide

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Sorafenib and triptolide as combination therapy for hepatocellular carcinoma.
    Surgery, 2014, Volume: 156, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Drug Synergism; Epoxy Compounds; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Nude; Models, Biological; NF-kappa B p50 Subunit; Niacinamide; Organophosphates; Phenanthrenes; Phenylurea Compounds; Prodrugs; Signal Transduction; Sincalide; Sorafenib; Translational Research, Biomedical; Xenograft Model Antitumor Assays

2014
[Effect of Low-Dose Triptolide and Sorafenib Alone and Their Combination on AML Cell Line MV411 and the Pathway of STAT5].
    Zhongguo shi yan xue ye xue za zhi, 2019, Volume: 27, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Diterpenes; Epoxy Compounds; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Phenanthrenes; Sorafenib; STAT5 Transcription Factor

2019
Sorafenib and triptolide loaded cancer cell-platelet hybrid membrane-camouflaged liquid crystalline lipid nanoparticles for the treatment of hepatocellular carcinoma.
    Journal of nanobiotechnology, 2021, Nov-08, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomimetic Materials; Blood Platelets; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Diterpenes; Epoxy Compounds; Humans; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Phenanthrenes; RAW 264.7 Cells; Sorafenib

2021