sorafenib has been researched along with trichostatin a in 3 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (trichostatin a) | Trials (trichostatin a) | Recent Studies (post-2010) (trichostatin a) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 3,365 | 7 | 1,382 |
| Protein | Taxonomy | sorafenib (IC50) | trichostatin a (IC50) |
|---|---|---|---|
| Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | Aquifex aeolicus | 0.4 | |
| Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | Aquifex aeolicus | 0.4 | |
| Chain A, Histone deacetylase 7a | Homo sapiens (human) | 0.3 | |
| Chain A, Histone deacetylase 7a | Homo sapiens (human) | 0.3 | |
| Histone deacetylase 8 | Schistosoma mansoni | 3.62 | |
| Histone deacetylase | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 1 | Mus musculus (house mouse) | 0.0047 | |
| Histone deacetylase 3 | Homo sapiens (human) | 0.3388 | |
| 5-hydroxytryptamine receptor 3A | Cavia porcellus (domestic guinea pig) | 7.69 | |
| Histone deacetylase 3 | Mus musculus (house mouse) | 0.0014 | |
| Plasma kallikrein | Homo sapiens (human) | 0.034 | |
| Integrin beta-3 | Homo sapiens (human) | 0.0263 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.02 | |
| Integrin alpha-IIb | Homo sapiens (human) | 0.0263 | |
| Coagulation factor VII | Homo sapiens (human) | 0.034 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.005 | |
| Vitamin D3 receptor | Homo sapiens (human) | 0.087 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.028 | |
| Tissue factor | Homo sapiens (human) | 0.032 | |
| Adenosine receptor A1 | Bos taurus (cattle) | 0.19 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.005 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.1 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.8532 | |
| Histone deacetylase 2 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.2343 | |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | 0.5944 | |
| Histone deacetylase 1 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Adenosine receptor A1 | Sus scrofa (pig) | 0.2 | |
| Histone deacetylase | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 4 | Mus musculus (house mouse) | 0.0014 | |
| Polyamine deacetylase HDAC10 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 3 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | 1.2 | |
| Histone deacetylase 7 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 8 | Mus musculus (house mouse) | 0.0207 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.5052 | |
| Histone deacetylase 11 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.3475 | |
| HD2 type histone deacetylase HDA106 | Zea mays | 0.006 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 0.3266 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.5027 | |
| Histone deacetylase 9 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 7 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 6 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 4 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.4994 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.2559 | |
| Histone deacetylase 9 | Homo sapiens (human) | 0.5627 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.5332 | |
| Histone deacetylase | Plasmodium falciparum (malaria parasite P. falciparum) | 0.0006 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.0138 | |
| Histone deacetylase 6 | Mus musculus (house mouse) | 0.0387 | |
| Histone deacetylase 5 | Mus musculus (house mouse) | 0.0107 | |
| Histone deacetylase | Zea mays | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, D; Goh, WH; Soh, CK; Wang, H | 1 |
| Abuo-Rahma, GEA; Badr, M; Bass, AKA; El-Zoghbi, MS; Mohamed, MFA; Nageeb, EM | 1 |
| Chen, SS; Lee, HY; Lee, S; Liu, YT; Tai, HC; Tuan, YL; Wang, HH; Wang, SW; Yen, JY; Yu, CL | 1 |
1 review(s) available for sorafenib and trichostatin a
| Article | Year |
|---|---|
Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors.
Topics: Androgen Antagonists; Animals; Antineoplastic Agents; Benzimidazoles; Cyclic Nucleotide Phosphodiesterases, Type 5; Daunorubicin; Doxorubicin; fms-Like Tyrosine Kinase 3; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Targeted Therapy; Morpholines; Nicotinamide Phosphoribosyltransferase; Nitric Oxide; Pyrimidines; Quinazolines; Structure-Activity Relationship; Transcription Factors | 2021 |
2 other study(ies) available for sorafenib and trichostatin a
| Article | Year |
|---|---|
Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Screening Assays, Antitumor; Heterografts; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2018 |
Effect of phenylurea hydroxamic acids on histone deacetylase and VEGFR-2.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Molecular Structure; Phenylurea Compounds; Protein Kinase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-2 | 2021 |