sorafenib has been researched along with thiourea in 4 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (thiourea) | Trials (thiourea) | Recent Studies (post-2010) (thiourea) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 6,959 | 46 | 1,737 |
| Protein | Taxonomy | sorafenib (IC50) | thiourea (IC50) |
|---|---|---|---|
| Urease | Canavalia ensiformis (jack bean) | 0.56 | |
| Serine-protein kinase ATM | Homo sapiens (human) | 0.2 | |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, Z; Wang, ZX; Wei, P; Yang, Z | 1 |
| Chen, J; He, Z; Sun, W; Xu, W; Yao, J | 1 |
| Fu, F; Kong, X; Sun, S; Wang, H; Wang, N; Yao, J; Zhang, J | 1 |
| Al-Ansary, GH; Fayad, W; Mahgoub, S; Nasr, T; Taha, H | 1 |
4 other study(ies) available for sorafenib and thiourea
| Article | Year |
|---|---|
[Synthesis and biological evaluation of sorafenib thiourea derivatives].
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Structure; Niacinamide; Phenylurea Compounds; Sorafenib; Thiourea | 2011 |
Design, synthesis and biological activities of thiourea containing sorafenib analogs as antitumor agents.
Topics: Antineoplastic Agents; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyridines; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Structure-Activity Relationship; Thiourea | 2012 |
Design and Discovery of Quinazoline- and Thiourea-Containing Sorafenib Analogs as EGFR and VEGFR-2 Dual TK Inhibitors.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; ErbB Receptors; Humans; Melanoma, Experimental; Mice, Inbred C57BL; Molecular Docking Simulation; Protein Binding; Quinazolines; Sorafenib; Thiourea; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2017 |
Biphenylurea/thiourea derivatives tagged with heteroarylsulfonamide motifs as novel VEGFR2 inhibitors; Design, synthesis and anti-angiogenic activity.
Topics: Angiogenesis Inhibitors; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Protein Kinase Inhibitors; Sorafenib; Structure-Activity Relationship; Sulfonamides; Thiourea; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2021 |