sorafenib has been researched along with sphingosine in 3 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (sphingosine) | Trials (sphingosine) | Recent Studies (post-2010) (sphingosine) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 8,325 | 117 | 3,459 |
| Protein | Taxonomy | sorafenib (IC50) | sphingosine (IC50) |
|---|---|---|---|
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | 6.3125 | |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | 0.098 | |
| Sphingosine kinase 2 | Homo sapiens (human) | 1.56 | |
| Sphingosine kinase 1 | Homo sapiens (human) | 3.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beljanski, V; Lewis, CS; Smith, CD | 1 |
| Ara, T; Buettner, R; DeClerck, YA; Jove, R; Jove, V; Nam, S; Seeger, R; Wang, Y; Wu, J; Xin, H; Xu, Y; Yang, F; Yu, H | 1 |
| An, D; Dong, M; Feng, M; Guan, Z; Jiang, S; Kuerban, K; Li, J; Peng, Y; Wang, Q; Ye, L | 1 |
3 other study(ies) available for sorafenib and sphingosine
| Article | Year |
|---|---|
Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts.
Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Carcinoma, Hepatocellular; Flow Cytometry; Hep G2 Cells; Humans; Liver Neoplasms; Lysophospholipids; Mice; Mitogen-Activated Protein Kinases; Niacinamide; Phenylurea Compounds; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Sorafenib; Sphingosine; Xenograft Model Antitumor Assays | 2011 |
Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Janus Kinase 2; Lysophospholipids; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinases; Neuroblastoma; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyridines; Signal Transduction; Sorafenib; Sphingosine; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2012 |
C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Flow Cytometry; Humans; Niacinamide; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Sorafenib; Sphingosine; TOR Serine-Threonine Kinases | 2017 |