Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and sildenafil citrate

sorafenib has been researched along with sildenafil citrate in 4 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(sildenafil citrate)		Trials
(sildenafil citrate)		Recent Studies (post-2010) (sildenafil citrate)
6,5207305,2515,8629562,319

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)sildenafil citrate (IC50)
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.0036

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Booth, L; Chuckalovcak, J; Cruickshanks, N; Dent, P; Hamed, HA; Poklepovic, A; Roberts, JL; Tavallai, M1
Booth, L; Carter, J; Dent, P; McGuire, WP; Poklepovic, A; Roberts, JL; Webb, T1
Booth, L; Dent, P; Poklepovic, A; Roberts, JL1

Other Studies

4 other study(ies) available for sorafenib and sildenafil citrate

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Nexavar/Stivarga and viagra interact to kill tumor cells.
    Journal of cellular physiology, 2015, Volume: 230, Issue:9

    Topics: Apoptosis; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Neoplasm Proteins; Neoplasms; Niacinamide; Phenylurea Compounds; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sorafenib; Sulfonamides; Xenograft Model Antitumor Assays

2015
Celecoxib enhances [sorafenib + sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistance.
    Cancer biology & therapy, 2015, Volume: 16, Issue:11

    Topics: Antineoplastic Agents; Carboplatin; Celecoxib; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Female; Humans; Inhibitory Concentration 50; Niacinamide; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Phenylurea Compounds; Sildenafil Citrate; Sorafenib

2015
PDE5 inhibitors enhance the lethality of [pemetrexed + sorafenib].
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Drug Synergism; Humans; Lung Neoplasms; Mice; Neoplasms, Experimental; Niacinamide; Pemetrexed; Phenylurea Compounds; Phosphodiesterase 5 Inhibitors; Sildenafil Citrate; Sorafenib; Xenograft Model Antitumor Assays

2017