Page last updated: 2024-09-05

sorafenib and sch 527123

sorafenib has been researched along with sch 527123 in 2 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(sch 527123)
Trials
(sch 527123)
Recent Studies (post-2010) (sch 527123)
6,5207305,25118012

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)sch 527123 (IC50)
Bile salt export pumpHomo sapiens (human)10
C-X-C chemokine receptor type 1Homo sapiens (human)0.1021
C-X-C chemokine receptor type 2Homo sapiens (human)0.1183
C-X-C chemokine receptor type 2Mus musculus (house mouse)0.0081

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chu, B; Jiang, Y; Li, Q; Liu, Z; Luo, J; Shi, Z; Xin, Q; Ye, L; Zhan, F; Zhang, X; Zhu, Q1

Other Studies

2 other study(ies) available for sorafenib and sch 527123

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Design, synthesis and anti-tumor evaluation of 1,2,4-triazol-3-one derivatives and pyridazinone derivatives as novel CXCR2 antagonists.
    European journal of medicinal chemistry, 2021, Dec-15, Volume: 226

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyridazines; Receptors, Interleukin-8B; Structure-Activity Relationship; Triazoles

2021