Page last updated: 2024-09-05

sorafenib and pyrazole

sorafenib has been researched along with pyrazole in 2 studies

Compound Research Comparison

Studies (sorafenib)	Trials (sorafenib)	Recent Studies (post-2010) (sorafenib)	Studies (pyrazole)	Trials (pyrazole)	Recent Studies (post-2010) (pyrazole)
6,520	730	5,251	1,152	0	596

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Getlik, M; Grütter, C; Pawar, V; Rabiller, M; Rauh, D; Simard, JR; Wulfert, S	1
Hah, JM; Kim, H; Kim, M; Kim, MH; Sim, T; Yoo, KH; Yu, H	1

Other Studies

2 other study(ies) available for sorafenib and pyrazole

Article	Year
Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors. Journal of the American Chemical Society, 2009, Sep-23, Volume: 131, Issue:37 Topics: Adenosine Triphosphate; Allosteric Regulation; Amino Acid Sequence; Benzenesulfonates; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Stability; Fluorescent Dyes; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Niacinamide; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Reproducibility of Results; Small Molecule Libraries; Sorafenib; Structure-Activity Relationship	2009
Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells. Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6 Topics: Amides; Antineoplastic Agents; Benzenesulfonates; Binding Sites; Cell Line, Tumor; Computer Simulation; Humans; Melanoma; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrazoles; Pyridines; raf Kinases; Sorafenib; Structure-Activity Relationship	2011

Article

Year

Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.

Journal of the American Chemical Society, 2009, Sep-23, Volume: 131, Issue:37

Topics: Adenosine Triphosphate; Allosteric Regulation; Amino Acid Sequence; Benzenesulfonates; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Stability; Fluorescent Dyes; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Niacinamide; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Reproducibility of Results; Small Molecule Libraries; Sorafenib; Structure-Activity Relationship

2009

Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells.

Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

Topics: Amides; Antineoplastic Agents; Benzenesulfonates; Binding Sites; Cell Line, Tumor; Computer Simulation; Humans; Melanoma; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrazoles; Pyridines; raf Kinases; Sorafenib; Structure-Activity Relationship

2011