sorafenib has been researched along with pf-4708671 in 2 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (pf-4708671) | Trials (pf-4708671) | Recent Studies (post-2010) (pf-4708671) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 44 | 0 | 42 |
| Protein | Taxonomy | sorafenib (IC50) | pf-4708671 (IC50) |
|---|---|---|---|
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | 0.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Choi, HN; Hong, SE; Jin, HO; Kim, EK; Kim, HA; Kim, JH; Lee, JK; Noh, WC; Park, IC | 1 |
2 other study(ies) available for sorafenib and pf-4708671
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Inhibition of S6K1 enhances glucose deprivation-induced cell death via downregulation of anti-apoptotic proteins in MCF-7 breast cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Down-Regulation; Female; Gene Knockdown Techniques; Glucose; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Myeloid Cell Leukemia Sequence 1 Protein; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Ribosomal Protein S6 Kinases, 70-kDa; Sorafenib; Survivin; TOR Serine-Threonine Kinases | 2013 |