Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and pd 153035

sorafenib has been researched along with pd 153035 in 1 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(pd 153035)		Trials
(pd 153035)		Recent Studies (post-2010) (pd 153035)
6,5207305,251232261

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)pd 153035 (IC50)
Cyclin-G-associated kinaseHomo sapiens (human)0.26
Mitogen-activated protein kinase 13Homo sapiens (human)6.3
Dihydrofolate reductaseHomo sapiens (human)0.2
Dihydrofolate reductaseMus musculus (house mouse)0.2
Tyrosine-protein kinase ABL1Homo sapiens (human)0.03
Tyrosine-protein kinase transforming protein AblAbelson murine leukemia virus0.4787
Epidermal growth factor receptorHomo sapiens (human)0.1416
Protein kinase C alpha typeBos taurus (cattle)0.4787
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.735
Cyclin-dependent kinase 1Homo sapiens (human)0.4787
Fructose-1,6-bisphosphatase 1Homo sapiens (human)1
Platelet-derived growth factor receptor betaHomo sapiens (human)0.2
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.709
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.4787
Dihydrofolate reductasePneumocystis carinii0.2
Potassium-transporting ATPase subunit betaSus scrofa (pig)0.03
Potassium-transporting ATPase alpha chain 1Sus scrofa (pig)0.03
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.8445
Mitogen-activated protein kinase 12Homo sapiens (human)6.3
Mitogen-activated protein kinase 11Homo sapiens (human)6.3
Mitogen-activated protein kinase 14Homo sapiens (human)6.3
Dihydrofolate reductaseRattus norvegicus (Norway rat)0.2
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)0.63
Histamine H3 receptorRattus norvegicus (Norway rat)1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2.025

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, Y; He, J; Li, Y; Liu, M; Liu, Y; Xiao, J; Yu, W; Zhang, Q1

Reviews

1 review(s) available for sorafenib and pd 153035

ArticleYear
The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.
    Bioorganic & medicinal chemistry, 2019, 02-01, Volume: 27, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Humans; Neoplasms; Protein Kinase Inhibitors; Protein Kinases; Quinazolines

2019