sorafenib has been researched along with orlistat in 3 studies
Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (orlistat) | Trials (orlistat) | Recent Studies (post-2010) (orlistat) |
---|---|---|---|---|---|
6,520 | 730 | 5,251 | 1,432 | 274 | 539 |
Protein | Taxonomy | sorafenib (IC50) | orlistat (IC50) |
---|---|---|---|
Phosphatidylserine lipase ABHD16A | Homo sapiens (human) | 0.1 | |
Pancreatic triacylglycerol lipase | Sus scrofa (pig) | 0.4214 | |
Lipoprotein lipase | Homo sapiens (human) | 0.066 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 0.42 | |
Hepatic triacylglycerol lipase | Homo sapiens (human) | 0.003 | |
Pancreatic triacylglycerol lipase | Homo sapiens (human) | 0.3253 | |
Translocator protein | Rattus norvegicus (Norway rat) | 1 | |
Cytochrome P450 2C19 | Homo sapiens (human) | 0.42 | |
Kappa-type opioid receptor | Mus musculus (house mouse) | 0.1903 | |
Fatty acid synthase | Homo sapiens (human) | 2.99 | |
Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 0.01 | |
Platelet-activating factor acetylhydrolase | Homo sapiens (human) | 0.05 | |
Diacylglycerol lipase-alpha | Mus musculus (house mouse) | 0.02 | |
Lysophosphatidylserine lipase ABHD12 | Homo sapiens (human) | 0.1682 | |
Diacylglycerol lipase-beta | Homo sapiens (human) | 0.24 | |
Monoacylglycerol lipase ABHD6 | Homo sapiens (human) | 0.03 | |
Acyl-protein thioesterase 2 | Rattus norvegicus (Norway rat) | 0.17 | |
Diacylglycerol lipase-alpha | Homo sapiens (human) | 0.2677 | |
Endothelial lipase | Homo sapiens (human) | 0.006 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 2 (66.67) | 2.80 |
Authors | Studies |
---|---|
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Chen, J; Chen, T; Cui, Y; Ge, C; Geng, Q; Jin, W; Li, H; Li, J; Lin, H; Liu, T; Miao, C; Tian, H; Xiao, X; Xie, H; Yao, M; Yu, J; Zhao, F; Zhou, Q | 1 |
Cheng, Z; Dai, W; Feng, J; Guo, C; Ji, J; Li, J; Li, Y; Wu, J; Wu, L; Xu, X; Yang, M; Yang, W; Zhang, J; Zheng, Y | 1 |
1 review(s) available for sorafenib and orlistat
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for sorafenib and orlistat
Article | Year |
---|---|
Sperm associated antigen 4 promotes SREBP1-mediated de novo lipogenesis via interaction with lamin A/C and contributes to tumor progression in hepatocellular carcinoma.
Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lamin Type A; Lipogenesis; Liver Neoplasms; Mice; Orlistat; Sorafenib; Sterol Regulatory Element Binding Protein 1 | 2022 |
Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Fatty Acid Synthases; Ferroptosis; Humans; Liver Neoplasms; Orlistat; Sorafenib | 2023 |