sorafenib has been researched along with niclosamide in 2 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (niclosamide) | Trials (niclosamide) | Recent Studies (post-2010) (niclosamide) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 979 | 19 | 465 |
| Protein | Taxonomy | sorafenib (IC50) | niclosamide (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 13.7 | |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | 10 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.28 | |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | 10 | |
| Signal transducer and activator of transcription 3 | Homo sapiens (human) | 0.23 | |
| Anoctamin-1 | Homo sapiens (human) | 0.028 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butte, AJ; Chen, B; Chua, MS; Gill, RM; Ma, L; So, S; Wei, W; Yang, B | 1 |
| An, L; Chen, L; Dai, Z; Feng, Y; Gan, H; Gong, C; Haydon, RC; He, F; He, TC; Huang, B; Huang, S; Ji, X; Lei, J; Liu, B; Liu, F; Liu, W; Luu, HH; Shu, Y; Wang, X; Wu, K; Wu, X; Wu, Y; Yan, S; Yang, C; Yu, X; Yuan, C; Zeng, L; Zeng, Z; Zhang, B; Zhang, L; Zhang, R; Zhang, W; Zhao, C | 1 |
2 other study(ies) available for sorafenib and niclosamide
| Article | Year |
|---|---|
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Proliferation; Chaperonins; Computational Biology; Computer Simulation; Databases, Genetic; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Ethanolamine; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hep G2 Cells; HSP90 Heat-Shock Proteins; Humans; Liver Neoplasms; Male; Molecular Chaperones; Niacinamide; Niclosamide; Phenylurea Compounds; Signal Transduction; Sorafenib; Time Factors; Transcriptome; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells.
Topics: Carcinoma, Renal Cell; Cell Cycle; Drug Synergism; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Neoplasm Proteins; Niacinamide; Niclosamide; Phenylurea Compounds; PTEN Phosphohydrolase; Sorafenib | 2018 |