Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea

sorafenib has been researched along with n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea in 3 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea)		Trials
(n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea)		Recent Studies (post-2010) (n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea)
6,5207305,25194061

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea (IC50)
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.104
Glycogen synthase kinase-3 betaHomo sapiens (human)0.1269
Glycogen synthase kinase-3 betaMus musculus (house mouse)0.1
Cysteine protease ATG4BHomo sapiens (human)1.6

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Huang, CF; Liu, HS; Ramesh, C; Su, CL; Tseng, CL; Yao, CF1

Other Studies

3 other study(ies) available for sorafenib and n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Using gene expression database to uncover biology functions of 1,4-disubstituted 1,2,3-triazole analogues synthesized via a copper (I)-catalyzed reaction.
    European journal of medicinal chemistry, 2017, May-26, Volume: 132

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Copper; Curcumin; Databases, Genetic; Glycogen Synthase Kinase 3; Humans; Liver Neoplasms; Structure-Activity Relationship; Thiazoles; Triazoles; Urea

2017