sorafenib has been researched along with mitoxantrone hydrochloride in 1 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (mitoxantrone hydrochloride) | Trials (mitoxantrone hydrochloride) | Recent Studies (post-2010) (mitoxantrone hydrochloride) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 23 | 0 | 17 |
| Protein | Taxonomy | sorafenib (IC50) | mitoxantrone hydrochloride (IC50) |
|---|---|---|---|
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | 0.0509 | |
| DNA-(apurinic or apyrimidinic site) endonuclease | Homo sapiens (human) | 2 | |
| DNA-3-methyladenine glycosylase | Homo sapiens (human) | 2.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, N; Li, L; Li, W; Wan, X; Xie, Y; Zhang, W | 1 |
1 other study(ies) available for sorafenib and mitoxantrone hydrochloride
| Article | Year |
|---|---|
A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling.
Topics: Amino Acid Sequence; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Approval; Fungal Proteins; Genomics; Humans; Ligands; Mitogen-Activated Protein Kinases; Mitoxantrone; Molecular Docking Simulation; Protein Conformation; Protein Kinase Inhibitors; Substrate Specificity | 2013 |