Page last updated: 2024-09-05

sorafenib and mebendazole

sorafenib has been researched along with mebendazole in 2 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(mebendazole)
Trials
(mebendazole)
Recent Studies (post-2010) (mebendazole)
6,5207305,2512,089184438

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)mebendazole (IC50)
Tyrosine-protein kinase ABL1Homo sapiens (human)5
Vascular endothelial growth factor receptor 2Homo sapiens (human)5.5667
Calmodulin-domain protein kinase 1Toxoplasma gondii0.67

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ghanim, AMH; Saber, S; Younis, NS1

Reviews

1 review(s) available for sorafenib and mebendazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for sorafenib and mebendazole

ArticleYear
Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma.
    Scientific reports, 2019, 12-13, Volume: 9, Issue:1

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyclin D1; Diethylnitrosamine; Hep G2 Cells; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Liver Neoplasms; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Mebendazole; Mice; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Signal Transduction; Sorafenib; Tissue Inhibitor of Metalloproteinase-1; Tumor Burden; Vascular Endothelial Growth Factor A

2019