Page last updated: 2024-09-05

sorafenib and lopinavir

sorafenib has been researched along with lopinavir in 3 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(lopinavir)
Trials
(lopinavir)
Recent Studies (post-2010) (lopinavir)
6,5207305,2512,3834991,358

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)lopinavir (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)1.7
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 29.12
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.035
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)8.5114
Protease Human immunodeficiency virus 10.025
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.6
Protease Human immunodeficiency virus 10.0175

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Abou-El-Naga, IF; Fawzy Hussien Mogahed, NM; Mady, RF1

Reviews

1 review(s) available for sorafenib and lopinavir

ArticleYear
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Other Studies

2 other study(ies) available for sorafenib and lopinavir

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
In vitro effectivity of three approved drugs and their synergistic interaction against Leishmania infantum.
    Biomedica : revista del Instituto Nacional de Salud, 2020, 05-01, Volume: 40, Issue:Supl. 1

    Topics: Auranofin; Drug Combinations; Drug Synergism; Leishmania infantum; Lopinavir; Parasitology; Ritonavir; Sorafenib

2020