Page last updated: 2024-09-05

sorafenib and labetalol

sorafenib has been researched along with labetalol in 3 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(labetalol)
Trials
(labetalol)
Recent Studies (post-2010) (labetalol)
6,5207305,2511,980450327

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)labetalol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.016
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.354
Beta-1 adrenergic receptorHomo sapiens (human)0.01
Cytochrome P450 2D6Homo sapiens (human)0.8
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.393
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.354
Alpha-1D adrenergic receptorHomo sapiens (human)0.521
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.393
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.037
Sodium-dependent dopamine transporter Homo sapiens (human)1.607
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.815

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Al-Ach, NN; Al-Tel, TH; Alshihabi, AM; Anbar, HS; El-Awady, R; El-Gamal, MI; El-Gamal, R; Kalla, RR; Munther, MA; Sbenati, RM; Shahin, AI; Shehata, MK; Tarazi, H; Tokatly, RT; Wahba, MM; Zaraei, SO1

Reviews

1 review(s) available for sorafenib and labetalol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for sorafenib and labetalol

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Design and synthesis of new quinoline derivatives as selective C-RAF kinase inhibitors with potent anticancer activity.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Hydroxyquinolines; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Quinolines; Sorafenib; Structure-Activity Relationship

2022