Page last updated: 2024-09-05

sorafenib and gw843682x

sorafenib has been researched along with gw843682x in 3 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(gw843682x)
Trials
(gw843682x)
Recent Studies (post-2010) (gw843682x)
6,5207305,25115011

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)gw843682x (IC50)
Aurora kinase AHomo sapiens (human)4.8
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.62
Platelet-derived growth factor receptor betaHomo sapiens (human)0.16
Cyclin-dependent kinase 2Homo sapiens (human)7.6
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.092
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.36
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.0382
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.002
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.0247

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giranda, VL; Johnson, EF; Luo, Y; Stewart, KD; Woods, KW1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

3 other study(ies) available for sorafenib and gw843682x

ArticleYear
Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.
    Biochemistry, 2007, Aug-21, Volume: 46, Issue:33

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Androstadienes; Binding Sites; Cell Cycle Proteins; Humans; Models, Molecular; Molecular Sequence Data; Peptide Library; Polo-Like Kinase 1; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Substrate Specificity; Wortmannin

2007
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013