sorafenib has been researched along with gw843682x in 3 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (gw843682x) | Trials (gw843682x) | Recent Studies (post-2010) (gw843682x) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 15 | 0 | 11 |
| Protein | Taxonomy | sorafenib (IC50) | gw843682x (IC50) |
|---|---|---|---|
| Aurora kinase A | Homo sapiens (human) | 4.8 | |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | 0.62 | |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | 0.16 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 7.6 | |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | 0.092 | |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | 0.36 | |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | 0.0382 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 0.002 | |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | 0.0247 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giranda, VL; Johnson, EF; Luo, Y; Stewart, KD; Woods, KW | 1 |
| Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
3 other study(ies) available for sorafenib and gw843682x
| Article | Year |
|---|---|
Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Androstadienes; Binding Sites; Cell Cycle Proteins; Humans; Models, Molecular; Molecular Sequence Data; Peptide Library; Polo-Like Kinase 1; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Substrate Specificity; Wortmannin | 2007 |
Navigating the kinome.
Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology | 2011 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |