sorafenib has been researched along with givinostat in 1 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (givinostat) | Trials (givinostat) | Recent Studies (post-2010) (givinostat) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 53 | 6 | 50 |
| Protein | Taxonomy | sorafenib (IC50) | givinostat (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.136 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.0793 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.524 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.293 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 0.331 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.287 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.837 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.0983 | |
| Histone deacetylase 9 | Homo sapiens (human) | 0.512 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.532 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.136 | |
| Histone deacetylase | Zea mays | 0.0075 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anichini, A; Carbone, A; Carlo-Stella, C; Cleris, L; Locatelli, SL; Malorni, W; Pierdominici, M; Saba, E; Stirparo, GG; Tartari, S | 1 |
1 other study(ies) available for sorafenib and givinostat
| Article | Year |
|---|---|
BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carbamates; Cell Line, Tumor; Histone Deacetylase Inhibitors; Hodgkin Disease; Humans; Imidazoles; Indoles; Membrane Proteins; Mice; Mice, SCID; Necrosis; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins; Reactive Oxygen Species; Sorafenib; Up-Regulation; Xenograft Model Antitumor Assays | 2014 |