Page last updated: 2024-09-05

sorafenib and estrone

sorafenib has been researched along with estrone in 3 studies

Compound Research Comparison

Studies (sorafenib)	Trials (sorafenib)	Recent Studies (post-2010) (sorafenib)	Studies (estrone)	Trials (estrone)	Recent Studies (post-2010) (estrone)
6,520	730	5,251	10,266	432	1,372

Protein Interaction Comparison

Protein	Taxonomy	estrone (IC50)
Estrogen receptor	Homo sapiens (human)	0.1261
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	6.589
17-beta-hydroxysteroid dehydrogenase type 1	Homo sapiens (human)	0.4134
Sodium-dependent serotonin transporter	Homo sapiens (human)	5.301
Estrogen receptor beta	Homo sapiens (human)	0.3743
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	3

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Acheampong, F; Halaweish, F; Mahnashi, M; Ostlund, T	1

Reviews

1 review(s) available for sorafenib and estrone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for sorafenib and estrone

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Estrone analogs as potential inhibitors targeting EGFR-MAPK pathway in non-small-cell lung cancer. Chemical biology & drug design, 2023, Volume: 101, Issue:6 Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclin D; ErbB Receptors; Estrone; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Sorafenib	2023

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

Estrone analogs as potential inhibitors targeting EGFR-MAPK pathway in non-small-cell lung cancer.

Chemical biology & drug design, 2023, Volume: 101, Issue:6

Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclin D; ErbB Receptors; Estrone; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Sorafenib

2023