sorafenib has been researched along with disulfiram in 3 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (disulfiram) | Trials (disulfiram) | Recent Studies (post-2010) (disulfiram) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 3,776 | 175 | 723 |
| Protein | Taxonomy | sorafenib (IC50) | disulfiram (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 10.1 | |
| Spike glycoprotein | Betacoronavirus England 1 | 9.35 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 9.35 | |
| type-1 angiotensin II receptor | Homo sapiens (human) | 6.637 | |
| perilipin-5 | Homo sapiens (human) | 1.622 | |
| perilipin-1 | Homo sapiens (human) | 6.959 | |
| apelin receptor | Homo sapiens (human) | 2.63 | |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | 4.2905 | |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | 85.03 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 9.35 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Carbamate kinase | Giardia intestinalis | 0.6 | |
| Retinal dehydrogenase 1 | Homo sapiens (human) | 0.13 | |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | 3.4 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 4 | |
| Procathepsin L | Homo sapiens (human) | 9.35 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 4.904 | |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | 1.3756 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 9.35 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.356 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.9171 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 3.218 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.158 | |
| D(4) dopamine receptor | Homo sapiens (human) | 3.15 | |
| C-X-C chemokine receptor type 2 | Homo sapiens (human) | 6.013 | |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | 1.51 | |
| Protein-lysine 6-oxidase | Homo sapiens (human) | 0.32 | |
| Lysine-specific demethylase 5A | Homo sapiens (human) | 10 | |
| Caspase-1 | Homo sapiens (human) | 1.8 | |
| Mu-type opioid receptor | Homo sapiens (human) | 3.511 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.084 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 6.103 | |
| C-C chemokine receptor type 2 | Homo sapiens (human) | 2.468 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
| C-C chemokine receptor type 4 | Homo sapiens (human) | 8.395 | |
| Gasdermin-D | Homo sapiens (human) | 0.4 | |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | 0.093 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 4.637 | |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 3 | |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | 0.059 | |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | 0.6 | |
| Monoglyceride lipase | Homo sapiens (human) | 0.8095 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 9.35 | |
| Gasdermin-D | Mus musculus (house mouse) | 0.4 | |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | 1.6 | |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | 0.15 | |
| large T antigen | Betapolyomavirus macacae | 10.73 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, Z; Hou, Y; Liu, X; Ni, X; Wang, L; Weng, X; Yang, C; Ye, C; Yu, X; Zhang, Y; Zheng, Q | 1 |
1 review(s) available for sorafenib and disulfiram
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for sorafenib and disulfiram
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Overcoming the compensatory increase in NRF2 induced by NPL4 inhibition enhances disulfiram/copper-induced oxidative stress and ferroptosis in renal cell carcinoma.
Topics: Animals; Carcinoma, Renal Cell; Copper; Disulfiram; Ferroptosis; Kidney Neoplasms; Mice; NF-E2-Related Factor 2; Oxidative Stress; Sorafenib | 2023 |