sorafenib has been researched along with digitoxin in 2 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (digitoxin) | Trials (digitoxin) | Recent Studies (post-2010) (digitoxin) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 5,259 | 90 | 219 |
| Protein | Taxonomy | sorafenib (IC50) | digitoxin (IC50) |
|---|---|---|---|
| STAT3, partial | Homo sapiens (human) | 0.7 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Sodium/potassium-transporting ATPase subunit alpha-1 | Homo sapiens (human) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit beta-1 | Homo sapiens (human) | 0.008 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.23 | |
| Sodium/potassium-transporting ATPase subunit alpha-3 | Homo sapiens (human) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit beta-2 | Homo sapiens (human) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit alpha-2 | Homo sapiens (human) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit alpha-1 | Canis lupus familiaris (dog) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit beta-3 | Homo sapiens (human) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit gamma | Homo sapiens (human) | 0.008 | |
| Sodium/potassium-transporting ATPase subunit alpha-4 | Homo sapiens (human) | 0.008 | |
| Solute carrier organic anion transporter family member 4C1 | Homo sapiens (human) | 0.12 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, PC; Guo, L; Huang, Y; Kwok, HF; Li, B; Li, L; Lin, Y; Meng, C; Neves, H; Xiao, Y; Yan, W | 1 |
2 other study(ies) available for sorafenib and digitoxin
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration.
Topics: Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Cardiotonic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Digitoxin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Sorafenib; Vascular Endothelial Growth Factor A | 2017 |