sorafenib has been researched along with d-alpha tocopherol in 7 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (d-alpha tocopherol) | Trials (d-alpha tocopherol) | Recent Studies (post-2010) (d-alpha tocopherol) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 32,198 | 2,903 | 7,258 |
| Protein | Taxonomy | sorafenib (IC50) | d-alpha tocopherol (IC50) |
|---|---|---|---|
| Glutathione S-transferase P | Homo sapiens (human) | 0.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, L; Liu, H; Liu, J; Liu, Y; Wang, X; Wang, Z; Yang, J | 1 |
| Du, X; Feng, H; Lei, M; Ma, G; Sha, S; Wang, X; Zhu, Y | 1 |
| Li, A; Liang, Y; Lyu, Y; Tang, X; Xie, D; Zheng, D | 1 |
| Li, X; Li, Z; Lian, D; Liu, J; Ye, L | 1 |
| Capelletti, MM; Manceau, H; Peoc'h, K; Puy, H | 1 |
| Gui, S; Guo, J; He, N; Huang, Y; Li, Z; Liang, X; Tang, M; Tao, Y | 1 |
2 review(s) available for sorafenib and d-alpha tocopherol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Ferroptosis in Liver Diseases: An Overview.
Topics: alpha-Tocopherol; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Cyclohexylamines; Cysteine; Ferroptosis; Glutathione; Heme; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lipid Peroxidation; Lipoxygenase; Liver Diseases; Liver Neoplasms; Oxidative Stress; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Sorafenib; Spiro Compounds; Sulfasalazine; Tumor Suppressor Protein p53 | 2020 |
5 other study(ies) available for sorafenib and d-alpha tocopherol
| Article | Year |
|---|---|
In vitro and in vivo evaluation of redox-responsive sorafenib carrier nanomicelles synthesized from poly (acryic acid) -cystamine hydrochloride-D-α-tocopherol succinate.
Topics: Acrylic Resins; alpha-Tocopherol; Animals; Cell Line, Tumor; Chemistry Techniques, Synthetic; Cystamine; Drug Carriers; Drug Liberation; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Male; Micelles; Nanostructures; Niacinamide; Oxidation-Reduction; Particle Size; Phenylurea Compounds; Rabbits; Rats; Sorafenib; Stereoisomerism | 2016 |
Dual-functionalized liposome by co-delivery of paclitaxel with sorafenib for synergistic antitumor efficacy and reversion of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Hyaluronic Acid; Liposomes; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Polyethylene Glycols; Polymers; Rats; Sorafenib; Vitamin E | 2019 |
Therapeutic Effect of Sorafenib-Loaded TPGS-
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Sorafenib; Vitamin E | 2018 |
Sorafenib-Loaded Nanoparticles Based on Biodegradable Dendritic Polymers for Enhanced Therapy of Hepatocellular Carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Dendrimers; Drug Delivery Systems; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Nanoparticles; Polymers; Sorafenib; Vitamin E; Xenograft Model Antitumor Assays | 2020 |
Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance.
Topics: alpha-Tocopherol; Animals; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Drug Resistance, Multiple; Glycolates; Humans; Lactic Acid; Liver Neoplasms; Mice; Mice, Nude; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sorafenib; Vitamin E | 2022 |