Page last updated: 2024-09-05

sorafenib and cortistatin a

sorafenib has been researched along with cortistatin a in 2 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(cortistatin a)
Trials
(cortistatin a)
Recent Studies (post-2010) (cortistatin a)
6,5207305,25129017

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)cortistatin a (IC50)
Rho-associated protein kinase 2Homo sapiens (human)0.22
Cyclin-CHomo sapiens (human)0.005
Cyclin-dependent kinase 8Homo sapiens (human)0.0085
Rho-associated protein kinase 1Homo sapiens (human)0.25
Cyclin-dependent kinase 19Homo sapiens (human)0.01

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kumarasiri, M; Philip, S; Teo, T; Wang, S; Yu, M1
Cai, T; Chen, T; Du, K; Gao, X; Luo, X; Shen, R; Sun, H; Wu, C; Wu, Y; Xi, M; Yu, L1

Reviews

2 review(s) available for sorafenib and cortistatin a

ArticleYear
Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy?
    Journal of medicinal chemistry, 2018, 06-28, Volume: 61, Issue:12

    Topics: Antineoplastic Agents; Cyclin-Dependent Kinase 8; Cytokines; Humans; Male; Molecular Targeted Therapy; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Transcription Factors; Tumor Escape

2018
CDK8 as a therapeutic target for cancers and recent developments in discovery of CDK8 inhibitors.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Colorectal Neoplasms; Cyclin-Dependent Kinase 8; Drug Discovery; Humans; Mediator Complex; Molecular Structure; Neoplasms; Oncogenes; Protein Kinase Inhibitors; Wnt Signaling Pathway

2019