sorafenib has been researched along with chir 99021 in 3 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (chir 99021) | Trials (chir 99021) | Recent Studies (post-2010) (chir 99021) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 272 | 1 | 258 |
| Protein | Taxonomy | sorafenib (IC50) | chir 99021 (IC50) |
|---|---|---|---|
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | 8.8 | |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 8.8 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 8.8 | |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | 0.0089 | |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | 0.0133 | |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | 8.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
3 other study(ies) available for sorafenib and chir 99021
| Article | Year |
|---|---|
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
Navigating the kinome.
Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology | 2011 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |