sorafenib has been researched along with capsaicin in 4 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (capsaicin) | Trials (capsaicin) | Recent Studies (post-2010) (capsaicin) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 11,238 | 661 | 3,410 |
| Protein | Taxonomy | sorafenib (IC50) | capsaicin (IC50) |
|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | Rattus norvegicus (Norway rat) | 0.019 | |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | 0.6 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 3 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.6755 | |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | 0.008 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Dong, LY; Du, C; Gao, JJ; Ni, YH; Qiao, Z; Sun, JY; Wang, K; Wang, LY; Yu, HX; Zhang, JH; Zhang, SS; Zhao, CR | 1 |
| Chen, H; Dai, N; Guo, P; He, Q; Ye, R; Zhang, Q | 1 |
| Badarau, IA; Caruntu, C; Constantin, C; Didilescu, AC; Mihai, GL; Neagu, M; Scheau, C | 1 |
1 review(s) available for sorafenib and capsaicin
| Article | Year |
|---|---|
Capsaicin: Effects on the Pathogenesis of Hepatocellular Carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Capsaicin; Carcinoma, Hepatocellular; Cell Differentiation; Cell Proliferation; Drug Synergism; Humans; Liver Neoplasms; Neovascularization, Pathologic; Oxidative Stress; Signal Transduction; Sorafenib; TRPV Cation Channels | 2019 |
3 other study(ies) available for sorafenib and capsaicin
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Capsaicin enhances the antitumor activity of sorafenib in hepatocellular carcinoma cells and mouse xenograft tumors through increased ERK signaling.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capsaicin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Mice; Niacinamide; Phenylurea Compounds; Sorafenib; Xenograft Model Antitumor Assays | 2018 |
Capsaicin and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capsaicin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sorafenib; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2018 |