Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and bms 777607

sorafenib has been researched along with bms 777607 in 3 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(bms 777607)		Trials
(bms 777607)		Recent Studies (post-2010) (bms 777607)
6,5207305,25152049

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)bms 777607 (IC50)
High affinity nerve growth factor receptorHomo sapiens (human)0.29
Tyrosine-protein kinase LckHomo sapiens (human)0.12
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.594
Hepatocyte growth factor receptorHomo sapiens (human)0.0343
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.144
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.028
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)0.55
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.0319
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.1635
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0167
Macrophage-stimulating protein receptorHomo sapiens (human)0.0389
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)0.0529
Tyrosine-protein kinase MerHomo sapiens (human)0.014
BDNF/NT-3 growth factors receptorHomo sapiens (human)0.19
Aurora kinase BHomo sapiens (human)0.078

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Guo, M; He, J; Jiang, X; Jiang, Y; Li, J; Liu, J; Ouyang, L; Wang, J; Zhang, J; Zhang, S1
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP1

Reviews

1 review(s) available for sorafenib and bms 777607

ArticleYear
Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Antineoplastic Agents; Drug Discovery; Humans; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Quinazolines; Quinolones; Receptors, Vascular Endothelial Growth Factor; Small Molecule Libraries

2016

Other Studies

2 other study(ies) available for sorafenib and bms 777607

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
The target landscape of clinical kinase drugs.
    Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays

2017