sorafenib has been researched along with bicalutamide in 4 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (bicalutamide) | Trials (bicalutamide) | Recent Studies (post-2010) (bicalutamide) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 1,313 | 212 | 541 |
| Protein | Taxonomy | sorafenib (IC50) | bicalutamide (IC50) |
|---|---|---|---|
| Progesterone receptor | Oryctolagus cuniculus (rabbit) | 5.6 | |
| Progesterone receptor | Homo sapiens (human) | 1.819 | |
| Androgen receptor | Homo sapiens (human) | 0.404 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.7168 | |
| Androgen receptor | Mus musculus (house mouse) | 1.835 | |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 0.12 | |
| Progesterone receptor | Rattus norvegicus (Norway rat) | 0.89 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Beardsley, EK; Chi, KN; Ellard, SL; Hotte, SJ; Kollmannsberger, C; Mukherjee, SD; North, S; Winquist, E | 1 |
1 review(s) available for sorafenib and bicalutamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for sorafenib and bicalutamide
| Article | Year |
|---|---|
A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Anilides; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Niacinamide; Nitriles; Orchiectomy; Phenylurea Compounds; Prostate-Specific Antigen; Prostatic Neoplasms; Pyridines; Sorafenib; Time Factors; Tosyl Compounds; Treatment Failure | 2012 |
2 other study(ies) available for sorafenib and bicalutamide
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |